Gene DDB0229877 (Slime mold)

DDB0229877

Species: Slime mold
Alias: DdisK140, DDB0229877
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: CDC15

Sequence

Name Sequence Type Origin Length Description Download
DDB0229877.AA Protein None 941 None Fasta, JSON
DDB0229877.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of DDB0229877.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229877.AA Dicty2 13-265 64 1.9e-211 708.75 In-house 1-264 (264) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-264/264
Sequence Identity: 64% (169 aa)

YQIG-EAVGKGAFGKVFKALNAETGDFCAIKQIE----KTIISEKQLPSIIQEIKLLQTLQHPNIVKFIESYETSRYLYFALEFIEGGSLAKIAKRYGCF
|||| |..||||||.|.|.|..|||||.|||||.    ||.|||.|..||.|||.||..|.|.||||.||..||...||..||.||.|||.||.|..|||
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCF

QEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGV---IKLADFGSCT---YSAIDRKLTVVGTPFWMAPEVIQMDMNARSTACDIWSLGCTLL
.|.|...|..||||||.|||..||||||||..||||||||.   |||||||..|   ||..|...||||||.|||||||||..|...|||||||||||..
PESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVVGTPYWMAPEVIQMSGNHCCTACDIWSLGCTII

EMLTGNPPYWDLGTMPAMFAMVNNPHPPIPNNISADLKHFLLACFVRDINKRPTASQLLEHPWI
|.||||||||||..|.|||.||...|||.||.||...|.||..||..|.|.|.||.|||.||||
ELLTGNPPYWDLNPMHAMFRMVQDDHPPLPNDISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase DDB0229877.AA STE 13-265 33 1.3e-115 390.39 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-359/359
Sequence Identity: 33% (121 aa)

YQIGEAVGKGAFGKVFKALNAE---------------TGDFCAIKQIE----KTIISE------------KQLPSIIQEIKLLQTLQ--HPNIVKFIESY
... | .||||||.|.||.| .               ||...||||..    .. . |            ... .|..|||... ..  ||||||.. .|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

ETSR-------YLYFALEFIEGGSLAKIAK-RYGCFQ-------------EPLLSRYFSQVLKG-LAYLHEKGVIHRDIKSDNILITKEGVIKLADFGSC
.          .|. ..|...|||| .| | .|||..             |......  |.||| |.|||....||||||..|||.     .||.||| |
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

TYSAID------------------RKLTVVGTPFWMAPEVIQMDMNA----RSTACDIWSLGCTLLEMLTGNPPYWDLGTMPAMFAMVNN----------
.  . .                  .  |.|||| |||||||| . ..     .| |||||||||..||.||.||. |.  | |||.. .|          
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----PHPPIPN-------------------NISADLKHFLLACFVRDINKRPTASQLLE--HPWI
     |.||.|.                   . | ..|.|.  |...| ||||||||||.  ||.|
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase DDB0229877.AA STE11 13-265 38 2.4e-105 356.29 In-house 1-303 (303) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-303/303
Sequence Identity: 38% (117 aa)

YQIGEAVGKGAFGKVFKALNAETGDFCAIKQIEKTIIS------EKQLPS------IIQEIKLLQTLQHPNIVKFIESYE---TSRYLYFALEFIEGGSL
.| ||  ||||||.|.|..|  || . |.||||   ..      ||.. |      | .||||...|.|.|||... .        ...  .|...||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

AKIAK-RYGC--FQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGV-IKLADFGSCTYSA--IDRKLT----------VVGTPF--------
. . . ..|.  |.|.. ..|  |.|.||.|||..|.|||||| .|||. ..|. .||||||.... |  . .. .          . |||.        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEVIQMDMNA-RSTACDIWSLGCTLLEMLTGNPPYWDLG--TMPAMFAMV-N-NPHPPIPNNIS------ADLKHFLLACFVRDINKRPTASQLLEH
|||||||        ....|||||||| .||.||.||. ...  .| |||  . . .|||||| ..|      .... ||. ||..| .|||||.|||.|
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

PWI
|.|
PFI
Kinase DDB0229877.AA S_TKc 13-265 35 1.6e-103 351.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

YQIGEAVGKGAFGKVFKALNAETGDFCAIKQIEKTIISEKQLPSIIQEIKLLQTLQHPNIVKFIESYETSRYLYFALEFIEG--GSLAKIAKRYGC----
|.|.. .||||||||.|. . .||  .|||.|           .|..||..|.  .||||||.......  .||. .|...|  |.| .. |..|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGVIKLADFGSCTYSAIDRKLTVVGTPFWMAPEVIQMDMNARST-ACDIWSLGCTLLEM
  | |    .|. |....|.|.|..|.||||.| .|||...  .||..|||...        |..|||..|||||.       .. .||.||.||.| ||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEM

LTGNPPYWDLGTMPAMFAMVNNPHPPIPNNISADLKHFLLACFVRDINKRPTASQLLE-------HPWI
|.| ||..   .| .|| ..           | ..|.|.  |...| .||||| ..|.       |||.
LCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0229877.AA Pkinase 13-265 32 3.4e-98 337.32 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-293/293
Sequence Identity: 32% (98 aa)

YQIGEAVGKGAFGKVFKALNAETGDFCAIKQIEKTIISEKQLPSIIQ--EIKLLQTLQHPNIVKFIESYETSRYLYFALEFIEGG----SLAKIAK--RY
|.||. .|.|.||.|.|. .  ||.  |.|.|.|  ...... . .   ||.... |.|||||......|.....|. .|. |||    .|. . .  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GCF--QEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGVI----KLADFGSCT---YSAIDRKLTVVGTPFWMAPEVIQMDMNARSTACDIWS
|||  .|  . .|. |.|.||.|.|..|.||||.|..|||| ..|.|    |..|||..    |       |..|||..||||||. . .  ....|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWS

LGCTLLEMLTGNPPYWDL----GTMPAMFAMVNNPHPPIPNNIS-----------------------ADLKHFLLACFVRDINKRPTASQLLEHPWI
.||.| |||.|.||...     . .  |. .... .||.. ...                        ..|.|.  |. .| .||||| |.|.|||.
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0229877.AA STE11-Unclassified 13-265 36 4.2e-98 332.22 In-house 1-308 (308) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-308/308
Sequence Identity: 36% (112 aa)

YQIGEAVGKGAFGKVFKALNAETGDFCAIKQIEKTIIS------EKQ-LPSIIQEIKLLQTLQHPNIVKFIESY--ETSRYLYFALEFIEGGSLAKIAKR
.| ||  |||.||.|.|..|..|| | |.||||.. ..      .|  ..||..|.|.|..| |.|||. .     .    ..  .| ..|||..   ..
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

YGCFQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGVIKLADFGSCTYSA------------------IDR-KL--------TVVGTPF---
|||| |.. . |  |.|.||||||..|.|||||| .|||| ..|..||.|||.  . .                  ..  ..        .  |||.   
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

WMAPEVIQMDMN-ARSTACDIWSLGCTLLEMLTGNPPYWDLGT---MPAMF-AMVNNPHPPIPNNIS-----------ADLKHFLLACFVRDINKRPTAS
|||||||    . . ... |||||||| .|| || .|. .. .   | |.. .   |  |.||.. |           ...| || .|| .| .|||||.
WMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTAN

QLLEHPWI
||| ||.|
QLLQHPFI
Kinase DDB0229877.AA STE20 13-265 38 2.8e-94 319.5 In-house 1-288 (288) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-288/288
Sequence Identity: 38% (113 aa)

YQIGEAVGKGAFGKVFKALNAETGDF----CAIKQIEKTIISE----KQLPSIIQEIKLLQTLQHPNIVKFIESYETS----RYLYFALEFIEGGSLAKI
|.. | .|.|..|||.|| . .||.     .|||...  . ..    ... .|..||  .. ..||||||...||  .      |. . |. .||||  |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMN--LEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDI

AK---RYGC------FQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGVIKLADFGSCTYSAI-----DR-K-LTVVGTPFWMAPEVIQMDM
 |   . |.      ..|.  .    .||.||.|||....||||||.||||.|..| .|||||| |          .. |  |.||||.|||||||| . 
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

---NARSTACDIWSLGCTLLEMLTGNPPYWDLGTMPAMFAMV--NNPHPPIPN----NISADLKHFLLACFVRDINKRPTASQLLEHPWI
   .   . ||||||| |..||..|.||| |.  | ||| .   .|| |.  .    . | ....|.  | ..| .|||||||||.||.|
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase DDB0229877.AA CAMK 18-265 19 2.1e-78 252.06 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-265
Range on HMM: 1-425/425
Sequence Identity: 19% (85 aa)

AVGKGAFGKVFKALNAETG------------DFCAIKQIEKTIIS--------------------------EKQLPSIIQEIKLLQTLQ-------HPNI
  |.|.||||... . .|.              .||| |.|. ..                          .| . .. .||.....||       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFIESYE------------TSRY--------LYFAL---EFIEGG----S-LAKIA-KRY-------------GCFQEPLLSRYFSQVLKGLAYLHEKG
.|..| ||            | ..        .|. .   |...||      . .|  ...             |.|.|   .||| |.. ...|.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VIHRDIKSDNILITKE-----------------GVIKLADFGSCTYSAIDRKLT-------------------------VVGTPFWMA-PEVIQM----D
..|||.| .|||...                  . ||..|||  ..   . ...                         ..|||  || |||..     .
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

M--------NARSTACDIWSLGCTLLEMLTGNPPYWDLG------------TMPAMFAMVNNPHPP-IPNN-----------------------ISADLK
|           . .||.||.|. |  ||.| ||...              ... .| .. .     .|                         .|.. |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

HFLLACFVRDINKRPTASQLLEHPWI
...  . ..| .||.|..| |.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DDB0229877.AA PAKA 13-265 36 5.6e-78 265.36 In-house 1-260 (260) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-260/260
Sequence Identity: 36% (96 aa)

YQIGEAVGKGAFGKVFKALNAETGDF--CAIKQIEKTIISEKQLPSIIQEIKLLQTLQHPNIVKFIESYETSRYLYFALEFIEGGSLAKIAKRYG-----
|.  | .|.|| |.|..| |..|..   .||||..    . |.|  || ||... . .|.|||..|.||  .. |. ..|. |||.|  . . .      
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKEL--IINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN

CFQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGVIKLADFGSCTYSAI--DRKLTVVGTPFWMAPEVIQMDMNARSTACDIWSLGCTLLEM
 ..|   .    ..|.|| ..|.|..|||||||||||. ..| .|..||| |.       .. |.|||| |||||||.   .  .   ||||||  ..||
YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIR--RKQYDEKVDIWSLGIMAIEM

LTGNPPYWDLGTMPAMFAMVNN--PHPPIPNNISADLKHFLLACFVRDINKRPTASQLLEHPWI
. | ||| .     ||.   .|  |.   |.. | ... || .|   |  .|..|..||.|| .
IEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase DDB0229877.AA Ciliate-E2 13-265 22 6.3e-78 265.21 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

YQIGEAVGKGAFGKVFKALNAETGDF------------------CAIKQIEKTIISEKQLPSIIQEIKLLQ----------------TLQHPNIVKFIES
| . .  |.|.||.|.|. . ...                    ..||.... |....|. .| |||....                .|.||||.|..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YE--TSRYLYFALEFIEGGSLAKIAK------------RYGCFQEPLLSRYFSQVLK---------------GLAYLHEKG-VIHRDIKSDNILITKEGV
..  .  ..|. .|...||.| .. |              ..| |   .... |.|.               .| |||.|. .|||||| .|||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKLADFGSCTYSAIDRK---------------------------------LTVVGTPFWMAPEVIQM-------DMNARSTACDIWSLGCTLLEMLTGNP
||..||| ...  .|..                                  |..|||  ||||....       . .  ...|||||||..| |||.|.|
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYWDLGTMPAMFAMVN--NPHPP----------------IPNNISADLKHFLLA----CFVRDINKRPT-ASQLLEHPWI
|.         .      .   |                .....| . |...      ....| .||.| ..|.|.|||.
PF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DDB0229877.AA ULK 13-265 28 6.9e-72 245.14 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-329/329
Sequence Identity: 28% (93 aa)

YQIGEAVGKGAFGKVFKALNAET----GDFCAIKQIEKT-IISEKQLP-------SIIQEIKLLQTL--------QHPNIVKFIESYETS--RYLYFALE
|.. .  |||.||||.|. | .|    .  .|.|.|.|  .. ....        ....|||....|        .||||||... .|||   ..|. .|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FIEGGSLAKIAKRYGC----------FQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKE------------GVIKLADFGSCTYSAID-----
. .|| | .. |...           . |.    .| | | |. .||....|||||| .||||..             ||.|.|||| .     |     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RKLTVV------GTPFWMAPEVIQ-M--DMNARSTACDIWSLGCTLLEMLTGNPPY--WDLGTMP-----AMFAM-------VNNPHPPIP-----NNIS
  .| |      |||  |||...| .   ..  .  |||||||| . |||.| ||.  |   .         .         ...  . .|     ..||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

ADLKHFLLACFVRDINKRPTASQLLEHPWI
 ..| ..  ....| ..| .  .|..|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase DDB0229877.AA Ciliate-E2-Unclassified 13-265 27 2.6e-71 243.23 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

YQIGEAVGKGAFGKVFKALNAETGDFCAIKQIEKTIISE-KQLPS---------IIQEIK-------------LLQTLQHPNIVKFIESYETSRYLYFAL
| |..  |.|.||||.|. . ... . |.|.. | .|   ||  .         .....|             .|. ..||.|||...  ..  ..|. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFIEGGSLAKIAKRY-----------------GCFQEPLLS-----RYFSQVLKGLAYLHEKG-VIHRDIKSDNILITKEG---VIKLADFGSCTYSA--
|..|||.| .. | .                  .|.|   .     .|| |.|.|| |||.|. .|||||| .|||....|    ||..|||.. ..   
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------IDRKLTVVGTPFWM----APEVIQMDMNARS--TACDIWSLGCTLLEMLTGNPPYWDLGTMP---------------AMFAMVNN
                ..  |..|||  |    ||||.|   .  |   .|||||||. | |||.|..|. |                     ..   ..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

------PHPP--IPNNISADLKHFLL----ACFVRDINKRPTASQLLEHPWI
      ..|.  || ..|   |.|.      ... ..|||.|..|.|.|||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase DDB0229877.AA Pkinase_Tyr 13-262 25 3.6e-32 109.59 Pfam 1-269 (270) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-269/270
Sequence Identity: 25% (71 aa)

YQIGEAVGKGAFGKVFKALNA----ETGDFCAIKQIEKTIISEKQ--LPSIIQEIKLLQTL-QHPNIVKFIESYE-TSRY--LYFALEFIEGGSLAKIAK
 ..|.  |.||||.|.|.       .|.  .|.| . |   ...|  . . ..|.|.. .| .|||||...      ..   .|  .|. ..|.| .  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RY----GCFQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGVIKLADFGSCTYS-AIDRKLTVVGT-----PFWMAPEVIQMDMNARSTACD
.     . .  . |  .  |. ||..||..|. ||||.   |.|.|...|.| .||| . .    |   .....      .|||||.|.      .|. |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK--FTTKSD

IWSLGCTLLEMLT-GNPP-YWDLGTMPAMFAMV--NNPHPPIPNNISADLKHFLLACFVRDINKRPTASQLLEH
.|| | .. |..| |  | |... .   .....  ..   |.| | .... . .. |   | ..||| |...|.
VWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQ
Kinase DDB0229877.AA TyrKc 13-265 23 2.2e-27 98.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YQIGEAVGKGAFGKVFKALNAETGDFCAIKQIEKTIISEKQLPSIIQEIKLLQTL--QHPNIVKFIESYETS-------RYLYFALEFIEGGSLAKIAKR
 . |.  | ||||.|.|.        .|.| . .       .  ...|....  |  .|||||...    ..         |.  .|. ..|.| .  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YGC-FQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGVIKLADFGSCTYSAID------RKLTVV----GTP-----FWMAPEVIQMDMNAR
..  .. . |  .  |. .| .|||.|..||||.   |.|.......| .||| . .   |       .  ..    |.       |||||.|    | .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYG

--STACDIWSLGCTLLEMLT-GNPPYWDL----GTMPAMFAMVNNP-HPPIPNN--------ISADLKHFLLACFVRDINKRPTASQLLEHPWI
  .|. |.|| | .. |..| | .||..      .   ... | .   .|.| |         ....    . |  .| ..||| |..  |  .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF