Gene tsunami (Slime mold)

tsunami

Species: Slime mold
Alias: tsunami, DdisK135, tsuA, DDB0229382
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: Fused

Sequence

Name Sequence Type Origin Length Description Download
tsunami.AA Protein None 2247 None Fasta, JSON
tsunami.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of tsunami.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase tsunami.AA ULK 5-257 32 6e-111 374.89 In-house 1-329 (329) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-329/329
Sequence Identity: 32% (108 aa)

YKLIGQIGEGSFGKVYKYRKKFT----GQLVACKVISKKGKNEEDIL--------SLRQEIDILKNLS--------HPNIIQFISCFENK--NEFTLVTE
| |. ..|.|||||||| |.| |    ...||||.|.|. .|..  .        .|..||.|.| |         ||||.... .||..  | . ...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YADG-DLSQIISEEKTLSVDL----------IQSICYQLVIALNYLHYKKVIHRDIKPQNILITSG------------GQIKVCDFGFAKTISSN-----
| .| ||.|.|.. |.|. |           ......|.. .. .|| ...||||||||||||. |            |..|..||||||.....     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

SILLTS----LKGTPLYLAPEIIQ----EQPYD-YKADLWSLGIILYQILVGSPPFSANSLADLVHMTLESNIEIPKELN------------------KY
 .. ..    |.||||| ||.|.|    ..||. ||.|.||||.|.|..|.| |||.|.   |.... ....|..|....                    
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PDLVSLFRQLLCKNPDKRIGWPDLLYHPFV
|.. .|.|..|......|| |..|. ||..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase tsunami.AA Fused 5-257 45 2.9e-108 366.0 In-house 1-251 (251) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-251/251
Sequence Identity: 45% (114 aa)

YKLIGQIGEGSFGKVYKYRKKFTGQLVACKVISKKGKNEEDILSLRQEIDILKNLSHPNIIQFISCFENKNEFTLVTEYADGDLSQIISEEKTLSVDLIQ
|     .|.|||| ||| |.|   . || |.|.|.|  .    .||.|..| . . ||.||  |  || . |   ||.|| ..| |. . . ..  . ..
YHVSEMVGQGSFGCVYKARRKYDSKVVAIKFIPKRGRSDKELKNLRRECEIMRRMHHPHIIHMIDSFETDKEVVVVTDYAEMELHQYLEYDGKMPEEQVR

SICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQIKVCDFGFAKTISSNSILLTSLKGTPLYLAPEIIQEQPYDYKADLWSLGIILYQILVGSPPFSAN
 |  .|| || |||   . |||.||||||   .. || ||||||   | | . ||| ||||||.||| . |||||  ||.|||| |||  .|| ||| ||
RIACHLVSALYYLHSHRILHRDMKPQNILLDKNMHIKLCDFGFARNMSINTHVLTSIKGTPLYMAPELVEEQPYDHHADMWSLGCILYELMVGQPPFCAN

SLADLVHMTLESNIEIPKELNKYPDLVSLFRQLLCKNPDKRIGWPDLLYHPFV
|   || | .  ..  |  .   .   .    || | | .|| ||.||.||||
SIFHLVSMIKHDDVKWPSTIT--SCCRNFLQGLLTKDPRHRISWPQLLCHPFV
Kinase tsunami.AA ULK 5-257 32 2.8e-107 362.71 In-house 1-324 (324) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-324/324
Sequence Identity: 32% (106 aa)

YKLIGQIGEGSFG-KVYKYR--KKFT-GQLVACKVISKKGKNEEDIL--------SLRQEIDILKNLS---HPN--IIQFISCFENK--NEFTLVTEYAD
| |. ..|.|||| |||| |  |. | .|.||||.|.||. |.   .        .|..|| |.| |    |||  |.... .||..  | . ...|| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-DLSQIISEEKTLSVDL----------IQSICYQLVIALNYLHYKKVIHRDIKPQNILITSG------------GQIKVCDFGFAKTISSNS---ILLT
| ||.|.| . |.|..            ......|.. .. .|| ...||||||||||||. |            |..|..||||||.. .|.    ...
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SLK------GTPLYLAPEIIQ----EQPYD-YKADLWSLGIILYQILVGSPPFSANSLADLVH------------MTLESNIEIPKELNK-----YPDLV
...      ||||| ||.|.|    ..||. ||.|.||||.|.|..| |..||...   |...            .... |  |.. ...      |.. 
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

SLFRQLLCKNPDKRIGWPDLLYHPFV
.|.|..|......|| |.... ||..
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase tsunami.AA S_TKc 5-257 33 3.7e-101 343.3 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

YKLIGQIGEGSFGKVYKYRKKFTGQLVACKVISKKGKNEEDILSLRQEIDILKNLSHPNIIQFISCFENKNEFTLVTEYADG---DLSQIISEEKT----
|... .||.|.|||||| |.| ||..||.|.|.          ..|.||.|||.  ||||.... .|.. ... .|.||.||   || ..| . ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSVDLIQSICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQIKVCDFGFAKTISSNSILLTSLKGTPLYLAPEIIQEQPYDY-KADLWSLGIILYQI
  ..   .....||.. ||.|.| ...||||.||.|||...  .||.||||.|. .       |.. ||| |.|||..   .|.. |.| ||.|.|||  
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LVGSPPFSANSLADLVHMTLESNIEIPKELNKYPDLVSLFRQLLCKNPDKRIGWPDLLY-------HPFV
|.| |||.   .. . .. .             |.. .. |..|.|.|.||..  ..|        ||..
LCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase tsunami.AA AGC 5-257 22 3.5e-97 251.18 In-house 1-395 (395) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-395/395
Sequence Identity: 22% (88 aa)

YKLIGQIGEGSFGKVYKYRKK------FTGQLVACKVISKKG---KNEE-DILSLRQE------------IDILKNLS----------HPNIIQ-FISCF
....  ||.|||||||  |||       ||.. |.||..||    .... ..     |             .||....          ||.|..   ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ENKNE--FTLVTEYAD----------G-DLSQIIS---EEKTLSVDLIQSICYQ-------LVIALNYLHY-KKVIHRD-IKPQNILITSGGQIKVCDFG
..|.     .| ||.           | .| ...     |.... . .. .. .       .| || |||  ...|||| .|| |||... | || .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKTISSNS--------------------------------------------------ILLTSLKG--TPLYLAPEIIQEQPYDYKADLWS--LGIILY
..| . ..                                                    . ... |  || |.||||.    |.. .| ||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

QILVGSPPFSANSLA----------DLVHMTL------ESNIEIP--------KELNKYPDLVSLFRQLLCKNPDKRIG----------WPDLLYHPFV
. |.| |||....            .. .  .      . ....|        .. .  |....| ..||||.|.||.|            ..  ||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase tsunami.AA Pkinase 5-257 33 2.4e-92 317.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-293/293
Sequence Identity: 33% (100 aa)

YKLIGQIGEGSFGKVYKYRKKFTGQLVACKVISKKGKNE-EDILSLR-QEIDILKNLSHPNIIQFISCFENKNEFTLVTEYADG-----DLSQIIS--EE
|.....||.||||.||| ..| ||..||.|.|.|..... .|.  .| .|| |.|.|.||||.... .||.|..  .|.||..|     ||. .||  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KTL--SVDLIQSICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQI----KVCDFGFAKTI-SSNSILLTSLKGTPLYLAPEIIQ-EQPYDYKADLWSL
...  | . .....||.. .|.|.| ...||||.||.|||| . |.|    |.||||.|| .   |.  .|.. ||| |.|||.|.  |.|..|.| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIILYQILVGSPPFSAN------SLADLVHMTLE--SNIEIPKELNKY-----------------PDLVSLFRQLLCKNPDKRIGWPDLLYHPFV
|.|||. | | |||.        .   .. ....     ..|.. ...                 ... .. . .|||.| ||......| ||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase tsunami.AA CAMKL 5-257 30 8.9e-84 267.21 In-house 1-297 (297) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-297/297
Sequence Identity: 30% (90 aa)

YKLIGQIGEGSFGKVYKYRK-KFTGQLVACKVISKKGKNEEDILS-------------LRQEIDILKNLS---HPNIIQFISCFENKNE------FTLVT
|... ..|.||||||   .  ..||. || |.| ||....... .             .|.|| |.| |.   |||||..  ..|...       . ||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYADGD---LSQIISEE----KTLSVDLIQSICYQLVIALNYLHYKKVIHRDIKPQNILITSGG--QIKVCDFGFAKTISSN----SILLTSLKGTPLYL
||..|    | . | ..    . .. .  . .  |.| |.||.| ....|||||| |||... |  .||..||||.  .  .      .|.   |.| | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIIQE--QPYD-YKADLWSLGIILYQILVGSPPFSANSLA-----DLVHMTLESNIEIPKE-LNKYP-DLVSLFRQLLCKNPDKRIGWPDLLYHPFV
||||.|   .||| .|.| ||.|.||| ...|  || . ...     .   . .. ..   ..   ... |. .| |..| .||.||.   ... ||..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase tsunami.AA CAMK 10-257 20 1.3e-83 269.17 In-house 1-425 (425) Show / Hide 
Range on Protein: 10-257
Range on HMM: 1-425/425
Sequence Identity: 20% (85 aa)

QIGEGSFGKVYKYRKKFTG------------QLVACKVISKKGKN--------------------------EEDILSLRQEIDILKNLS-------HPNI
..|.||||||.. . | |.            | ||.|.|.||                             ..|  ..|.||.|.|.|.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQFISCFEN-------------------KNEFTLVT---EYADGD------LSQIISEEK--------------TLSVDLIQSICYQLVIALNYLHYKKV
|...  .|.                   .... .|.   ||..|       .. |.. ..               .. .  . .  |.. |..|.| ...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPQNILITSG-----------------GQIKVCDFGFAKTISSN-----------------------SILLTSLKGTPLYLA-PEIIQ-------
.|||.|| |||...                  ..||..|||||. . ..                         ...   ||| | | ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EQPYDYKADLWSLGIILYQILVGSPPFSAN-------------SLADLVHMTLESNIE-IPKELNKYP---------------------DLVS
       ...|..|.| ||.|.|||  |.| ||| .              .. .| .. .. . . .|... . .                     .  .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LFRQLLCKNPDKRIGWPDLLYHPFV
| |..|...|.||.   . | ||..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase tsunami.AA Ciliate-E2-Unclassified 5-257 29 8.4e-82 278.07 In-house 1-352 (352) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-352/352
Sequence Identity: 29% (103 aa)

YKLIGQIGEGSFGKVYKYRKKFTGQLV-----ACKVISKK----GKNEEDILSLRQEID----------------ILKNLSHPNIIQFISCFENKNEFTL
||.| |||.|.|||||| ..| .. ..     ..|....|     ... .|.   .|.                 ||.|. ||.|. .. ||..|. . .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VTEYA-DGDLSQIISEEKT-----------------LSVDLIQ-----SICYQLVIALNYLHYKK-VIHRDIKPQNILITSGG---QIKVCDFGFAKTIS
|.||. .|||.|.|.. |.                 ..   ..      ...|.. .|.|||.|. .|||||||.|||....|   .||..|||..| . 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

SN---------------SILLTSLKGTPLYL----APEIIQEQPYD----YKADLWSLGIILYQILVGSPPFSANSLAD----------------LVHMT
.|               . ....  ||| |.    |||..|.| ||    ||.| ||||.|||..| | .||..|.  .                |    
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LESNIEIPKELN---------KYPDLVS-LFRQLLCKNPDKRIGWPDLLYHPFV
.. ||..||. .         .. |... |....| |||.|||.....| ||. 
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase tsunami.AA Ciliate-E2 5-257 26 1.3e-80 274.11 In-house 1-365 (365) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-365/365
Sequence Identity: 26% (99 aa)

YKLIGQIGEGSFGKVYKYRK-----------------------KFTGQLVACKVISKKG-KNEEDILSLRQEID----------ILKNLSHPNIIQFISC
||.| .||.|.||.||| ..                       |......| |...|.. .. . .... .||.          ||..|.|||||... |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NKNEFTLVTEYADG-DLSQIISEEKT---------------LSVDLIQSICY-----------QLVIALNYLHYKK-VIHRDIKPQNILITSGGQI
|.  ..| . ||.||..| || ..| . |.                  .... |..           ... ||.||| |. .|||||||.|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVCDFGFAKTISSNSI---------LLTSLK-----------------------GTPLYLAPEIIQEQP---------YDYKADLWSLGIILYQILVGSP
|..|||..| .. ...         ...  |                       ||| |.||||.. ..         ||||.|.||||.|||. | | |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFSANSLADLVHMTLESNIEIP----------------KELNKYPDLVSLFRQ----LLCKNPDKRIG-WPDLLYHPFV
||            .. .|..|                . ..  ..   |...    .|.|.|.|||. | ..| ||. 
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase tsunami.AA NEK 5-257 32 1.5e-77 263.98 In-house 1-286 (286) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-286/286
Sequence Identity: 32% (93 aa)

YKLIGQIGEGSFGKVYKYRKKFTGQL-----VACKVISKKGKNEEDILSLR-QEIDILKNLSHPNIIQFISCFENKN--EFTLVTEYAD--GDLSQI---
|..| .||.||||||||.|.| .|.      .. | |. .. .|..   .  .|. ||| | ||||. .. .|. ..   .  | ||..  |||.|    
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

ISEEK----TLSVDLIQSICYQLVIALNYLHYK-----KVIHRDIKPQNILITSGGQ----IKVCDFGFAKTISSNSILLTS-LKGTPLYLAPEIIQEQP
| . |     .. . |  ...|...||.|.|..     |..||||||||| .|. .     .|. ||| .|  .... .... . ||| |..||..|..|
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YDYKADLWSLGIILYQILVGSP--PFSAN--SLADLVHMTLESNIEIPKELN-K--Y-PDLVSLFRQLLCKNPDKRIGWPDLLYHPFV
|..|.| |||| .||..   .|  || |.  ..  |.    .   . .. .. .  | .|| .| .|.|.|.|..|    ..| .||.
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKG--PQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase tsunami.AA STE 5-257 24 7.5e-77 261.62 In-house 1-359 (359) Show / Hide 
Range on Protein: 5-257
Range on HMM: 1-359/359
Sequence Identity: 24% (88 aa)

YKLIGQIGEGSFGKVYKYRKK------FTGQL---------VACKVISKKGKN---------------EEDILSLRQEIDILKNLS--HPNIIQFISCFE
...|..||.|.||.||| ...       ||..         .| |..... .|               .|.. .. .||.|.|...  ||||.... |..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NK-------NEFTLVTEYAD-GDLSQIISEE----KTLS----------VDLIQSICYQLVIA-LNYLHYKKVIHRDIKPQNILITSGGQIKVCDFGFAK
..       .|  .. || | | |..|| .     |.|.           ..|  ||.|.. . |.||| ...|||||||.|||.     .| ||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

TISSNSI----------------LLTSLKGTPLYLAPEIIQE------QPYDYKADLWSLGIILYQILVGSPPFSA-NSLADLVHMTLESNIE-------
 .....                   ... ||| . |||.||       ..||.|.| ||||. .   . | ||..  . .  . ... .. ..       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---IPKELNKY----------------------PDLVSLFRQLLCKNPDKRIGWPDLLY--HPFV
    |    .                       |..    .. | |.|.||    .||   |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase tsunami.AA Pkinase_Tyr 5-192 28 2.4e-29 99.99 Pfam 1-205 (270) Show / Hide 
Range on Protein: 5-192
Range on HMM: 1-205/270
Sequence Identity: 28% (60 aa)

YKLIGQIGEGSFGKVYKYRKK----FTGQLVACKVISKKGKNEED--ILSLRQEIDILKNL-SHPNIIQFISCFE-NKNE--FTLVTEYADG-DLSQIIS
 ... ..|||.||.||| . |     |.. || |.. | |  .|.  . .. .|. |.|.| .||||.... .    .      .|.||. . ||     
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----EKTLSVDLIQSICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQIKVCDFGFAKTI--SSNS-ILLTSLKGTPL-YLAPEIIQEQPYDYKADLW
.    .. |..  . ..|.|   ...||. |. ||||.   |.|.|.....|.|||| |..|   ..     .. |  |   .||| |..  .  | | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVW

SLGIILY
| |. ..
SFGVLMW
Kinase tsunami.AA TyrKc 5-256 22 1.4e-19 72.25 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-256
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

YKLIGQIGEGSFGKVYKYRKKFTGQLVACKVISKKGKNEEDILSLRQEIDILKNL--SHPNIIQFISCFENK-------NEFTLVTEYAD-GDLSQIISE
 .|. ..||| ||.||| . |   . || |.. .       .  ...|. |...|  .||||.... .   .           .|.||.. ||| . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

EKT-LSVDLIQSICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQIKVCDFGFAKTISSN-------SILLT----SLKG-TPL-YLAPEIIQEQPYDY
 .  |...   |.|.|     .||| |..||||.   |.|.......|..||| .. | .        .   .    . |.  |.  .||| |..  .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KADLWSLGIILYQIL-VGSPPFSA-----NSLADLVHMTLESNIEIPKELN-------KYPDLVSLFRQLLCKNPDKRIGWPDLLYHPF
| | || |. .. |.  | .| .       | .....   . .   . . .         ... .. .|    .|..|    .. .. |
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase tsunami.AA Med15 500-835 8 1.5e-07 25.6 Pfam 422-463 (945) Show / Hide 
Range on Protein: 500-835
Range on HMM: 422-463/945
Sequence Identity: 8% (29 aa)

IQQQQQQQSQQQQMQQQQQQQQQQQQQQQQQQIPPQSPKVPQSPRVAPPPQSPRVLSSPRIAHSPKNSPRQTNPTSPSPSPRRNSLKSQQTPSLTNLNQA
..|...|| ||||.||||||.|.|.|||||||                                                                    
MRQHCDQQQQQQQQQQQQQQHQAQHQQQQQQQ--------------------------------------------------------------------

LVNPSSSSSSLNSSIPTSSSTNKQIPPLSSNLNQVNLSNNINDNNNIINNNSNNNSNNINNNINNNNNNNSNNINNNINNNINNINNNNNNNSNINNINN
                                                                                                    
----------------------------------------------------------------------------------------------------

INNNNNINSSNNNSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINSSNNNINNINNSNNNINNSNNNININNSNNNINGNRPTSGGNNDLIL
                                                                                                    
----------------------------------------------------------------------------------------------------

NNMLMNNISLSSSIESIASNNNSILVQQQLQQQQQQ
                          ||| |.|||.
--------------------------QQQQQHQQQM
Kinase tsunami.AA OmpH 524-878 6 0.000261 16.98 Pfam 45-115 (165) Show / Hide 
Range on Protein: 524-878
Range on HMM: 45-115/165
Sequence Identity: 6% (23 aa)

QQQQQQQQIPPQSPKVPQSPRVAPPPQSPRVLSSPRIAHSPKNSPRQTNPTSPSPSPRRNSLKSQQTPSLTNLNQALVNPSSSSSSLNSSIPTSSSTNKQ
...|.|..                                                                                            
EFKQWQAE--------------------------------------------------------------------------------------------

IPPLSSNLNQVNLSNNINDNNNIINNNSNNNSNNINNNINNNNNNNSNNINNNINNNINNINNNNNNNSNINNINNINNNNNINSSNNNSSNNNNNNNNN
                                                                                                    
----------------------------------------------------------------------------------------------------

NNNNNNNNNNNNNNNNNNNNNNNNNNIINSSNNNINNINNSNNNINNSNNNININNSNNNINGNRPTSGGNNDLILNNMLMNNISLSSSIESIASNNNSI
                                                                                                    
----------------------------------------------------------------------------------------------------

LVQQQLQQQQQQIQQQQQQIQLL-QQ-----------QQQIQIQQQQQIQQQQQLQ-IQLMQQQQQLN
     ||. |...|..||..|   ..           ||..| .||.  |.|||.|  ...|.||.|.
-----LQKMQKELQKEQQKYQKQIRAGTMSEEQRQKKQQEFQQKQQEFQQYQQQYQPQEMQQKQQELM
Kinase tsunami.AA OmpH 257-523 10 1.441141 3.81 Pfam 46-113 (165) Show / Hide 
Range on Protein: 257-523
Range on HMM: 46-113/165
Sequence Identity: 10% (27 aa)

VKSYNGAHVINNNNLNYNNNNNNNNNNNNNNNNGNRPITSAGGNYLNDNSSSPSISSPIQSLPLISADSLINSLNNNINNNNNNNNNNNNNNNNNNNNNN
.|..                                                                                                
FKQWQAE---------------------------------------------------------------------------------------------

NNNNNNNNNNNNNNNNNNNNNGNINTNGYYQPLQSPTSQNFVNGIPIPILNGISNPFSVYNNNNNMNNNNNNKFNPTSPKHHQTLQQQQQQQQQQQQQQQ
                                                                                    ||. |.. |..||. |
------------------------------------------------------------------------------------LQKMQKELQKEQQKYQ

QQ-QQ-QQQQQQQQQQQQQQQQQQIPPPQSPKTPKVLSPKAVGISIQQQQQQQSQQQQMQ-QQQQQQQQQ
.| ..  . ..| |. ||. |                         |.||. | .|||.| |. ||.||.
KQIRAGTMSEEQRQKKQQEFQ-------------------------QKQQEFQQYQQQYQPQEMQQKQQE
HEAT tsunami.AA HEAT 2009-2039 25 0.001318 16.35 Pfam 1-31 (31) Show / Hide 
Range on Protein: 2009-2039
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

LYGLLKKLLAHPEATVRAKTCNLIGNMFKYN
.  .| |.| .|.. ||. .|. .|.. .. 
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT tsunami.AA HEAT 2051-2081 38 0.000344 18.37 Pfam 1-31 (31) Show / Hide 
Range on Protein: 2051-2081
Range on HMM: 1-31/31
Sequence Identity: 38% (12 aa)

ILPILISRCIDVDLNTRKFACFALGNAAFHS
|||.|.. . | | . |. || .||. . |.
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT tsunami.AA HEAT 2134-2153 25 9.892418 2.93 Pfam 12-31 (31) Show / Hide 
Range on Protein: 2134-2153
Range on HMM: 12-31/31
Sequence Identity: 25% (5 aa)

EDEKTRSNVIGALGNLVRNS
.|.. |.... .||.|....
PDWEVREAACWCLGQLCEHC