Gene SLOB2 (Slime mold)
SLOB2
Sequence
Protein domains of SLOB2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | SLOB2.AA | Slob | 131-307 | 38 | 5.4e-111 | 375.05 | In-house | 50-268 (268) | Show / Hide |
Range on Protein: 131-307 Range on HMM: 50-268/268 Sequence Identity: 38% (84 aa) FRTIIKSLEIHPFISVPLLVDFIPEKHVAVSVRPFYADRGSLRDFIHKSKPKMPYADKYDT----------------HLQLN---EKIVSKFGRQILEAL |..|..|........|..||.||..||....|..|...||||.|||.|.|||||.|.||.. |...| .|.|.|..||||||| FMKILMSCHHPYIYPVINLVFFINHKHNYCCVIRFFNKRGSLKDFIYKAKPKMPWARKYCNKQPKSSSSSSSSSSSSHKKQNGLPMKQVQKYCRQILEAL IFLKNHNFPYFHLNSANVLVDD--QICLISDYENSFLGLEPRFSDFIRQHN---EKIDPDVLSFGLVLFEMACGYEMENP------------------HS |||....|||.||.|.||..|| ..|..||.||..||..|...|.|..|. |....||..||..|.||.|||.|.|. |. IFLHSKGFPYGHLHSGNVMIDDSNDCCRLSDIENCLLGMPPFYNDYIMWHRKIHEIENVDVYCFGHCLYEMCCGYPMQNHSVRNFPPCPFIALFCDKEHI VDISIPAHCYPEVRKVLEA ....|..||.|..|..|.. LSCEICKHCMPTMRQLLQM |
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S_TKc | SLOB2.AA | S_TKc | 75-328 | 18 | 0.000188 | -111.62 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 75-328 Range on HMM: 1-231/231 Sequence Identity: 18% (51 aa) YSLQDKIPK--FGSRSDKVYFGVLGNSLNKLENDRIMAMVPVSKHWPIPLNSEAGRTTFRTIIKSLEIHPFISVPLLVDFIPEKHVAVSVRPF----YAD | . .|| | || ||| .. . .||.|. .. ..|.. ..|. | .| .. . . . |.| YEILRKIGKGAFG----KVYKCRHKK------TGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCD R--GSLRDFIHKSKPKMPYADKYDTHLQLNEKIVSKFGRQILEALIFLKNHNFPYFHLNSANVLVDDQICLISDYENSFLGLEPRFSDF----------- |.|.|.|.| ... .. ...| . .. .||..|| .. .|.. . | .|.|.|. |.| . . . | GDLGDLFDYIKKRGRHGLR-------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----TTFCGTPWYMAPEV IRQHNE-KIDPDVLSFGLVLFEMACGYEMENPHSVDISIPAHCYPEVRKVLEAIFKPFYGTPITLEELSK-------MDFF . ... |. |. |.| .|.||.||| . . ||.. .. ... .| |. . . .| L-GYGKCKC--DWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | SLOB2.AA | TKL | 166-241 | 17 | 0.000472 | 10.5 | In-house | 119-198 (364) | Show / Hide |
Range on Protein: 166-241 Range on HMM: 119-198/364 Sequence Identity: 17% (17 aa) YADRGSLRDFIHKSKPKMPYADKYDTHLQLNEKIVSKFGRQILEALIFLKNHN--------FPYFHLNSANVLVDDQI---------------CLISDY |...|||....| .. ..| .. .| ..| . |.|.|.|||. | |.|. YCPGGSLLHYLH-------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDF |