Gene LvsG (Slime mold)
LvsG
Group:
Other
Family:
Other-Unique
Sequence
Protein domains of LvsG.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | LvsG.AA | SgK071 | 419-456 | 44 | 1.2e-08 | 26.18 | In-house | 112-149 (283) | Show / Hide |
Range on Protein: 419-456 Range on HMM: 112-149/283 Sequence Identity: 44% (17 aa) QLIQLFSFLHQREIVHGDLQPSNIHLNNQMWLGLEGFS |.. .||.|.|.| || |||| | .|| . | |. QMLHAIEYLHHRNIIHRDLKPSNIYLTDQMHCKLQDFG |
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| Kinase | LvsG.AA | DYRK2 | 416-447 | 37 | 7e-07 | 18.06 | In-house | 107-138 (318) | Show / Hide |
Range on Protein: 416-447 Range on HMM: 107-138/318 Sequence Identity: 37% (12 aa) MIYQLIQLFSFLHQREIVHGDLQPSNIHLNNQ ......| .|||.. |.|.|| | || |. . FAHSILQCLRFLHKNNIIHCDLKPENILLKQW |
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| Kinase | LvsG.AA | ERK7 | 415-445 | 38 | 8e-06 | 15.61 | In-house | 104-134 (292) | Show / Hide |
Range on Protein: 415-445 Range on HMM: 104-134/292 Sequence Identity: 38% (12 aa) FMIYQLIQLFSFLHQREIVHGDLQPSNIHLN ...|||.. ..| ...| || |||| |. YIMYQLLRAIKYMHSGNVIHRDLKPSNILLD |
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| Kinase | LvsG.AA | Dicty3 | 416-447 | 30 | 2.6e-05 | 13.26 | In-house | 309-341 (351) | Show / Hide |
Range on Protein: 416-447 Range on HMM: 309-341/351 Sequence Identity: 30% (10 aa) MIYQLIQLFSFLHQRE-IVHGDLQPSNIHLNNQ .| .|. . ...| . |.|.|. . || |.|. IICDLVKTLNYIHKNCHIIHRDIKCDNIMLDND |
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| Kinase | LvsG.AA | CDC2 | 417-447 | 45 | 5.5e-05 | 10.69 | In-house | 109-139 (301) | Show / Hide |
Range on Protein: 417-447 Range on HMM: 109-139/301 Sequence Identity: 45% (14 aa) IYQLIQLFSFLHQREIVHGDLQPSNIHLNNQ .||..| .|.||| |.| || |.|| .... MYQILQGVHFCHQRRIMHRDLKPQNILIDKK |
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| Kinase | LvsG.AA | PLK1 | 415-448 | 32 | 0.000469 | 8.93 | In-house | 103-136 (253) | Show / Hide |
Range on Protein: 415-448 Range on HMM: 103-136/253 Sequence Identity: 32% (11 aa) FMIYQLIQLFSFLHQREIVHGDLQPSNIHLNNQM . .||... .||. .|.| ||. |. ||... YYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHL |
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| Kinase | LvsG.AA | CDKL | 417-457 | 26 | 0.000916 | 8.75 | In-house | 104-145 (286) | Show / Hide |
Range on Protein: 417-457 Range on HMM: 104-145/286 Sequence Identity: 26% (11 aa) IYQLIQLFSFLHQREIVHGDLQPSNIHLN-NQMWLGLEGFSF ..|... .|.|. ..| | | || .. . . | .| | MWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGF |
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| Kinase | LvsG.AA | CMGC-Unique | 417-444 | 43 | 0.003948 | 6.29 | In-house | 319-348 (352) | Show / Hide |
Range on Protein: 417-444 Range on HMM: 319-348/352 Sequence Identity: 43% (13 aa) IYQLIQLFSFLHQREIVHGDLQP--SNIHL ..||.| ||| || || | . | | MKQLMQCLHFLHRMDYVHRDLKPRIYRILL |
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| Kinase | LvsG.AA | Ciliate-E2 | 81-442 | 5 | 0.07053 | 2.21 | In-house | 123-192 (365) | Show / Hide |
Range on Protein: 81-442
Range on HMM: 123-192/365
Sequence Identity: 5% (19 aa)
DLIK---DKSTSILLQYANKHNDHDLNKNKNNNNNSEENNNNSGEGDEDNTGEKAPPPAPSSPLSPSSSSSTSTTTTPLSTSISLNDLNSMPRKRTTIKY
|.|| |.....
DYIKNNKKKRNHEIE-------------------------------------------------------------------------------------
KQGSFEASSYDGDEISIQVVKKNWINNSNDNNSQQRPRLYERSLKTSQQQQQQQQQQFKFQPNETLSLWEYFDEINSPPMLYNIDQNNLNFTNNYIVQEK
----------------------------------------------------------------------------------------------------
LNSLDNKDDDDNNNNNNNSNSQSFTFNKEFIKSVLQSFSTYISSLPNSIHFTDTNIPPSIDYTSPNVLKLHPNLLPIIEIIYNDIDNNDNDNDDDDDKNN
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NNLNDKIFIIYKKYNYTLDGLLRYSLQYLQ-----RNQKITTFMIYQLIQLFSFLHQRE-IVHGDLQPSNI
. . ..|. .... | || |.| ..|. . .||.. |.| |. |.||
---------K-D-KYFTEKEIKYIMKQILQGFKTKA-----EFYIACIILALEYLHSKNNIIHRDIKPENI
|
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| Beach | LvsG.AA | Beach | 475-774 | 24 | 2.9e-59 | 208.0 | Pfam | 1-286 (286) | Show / Hide |
Range on Protein: 475-774 Range on HMM: 1-286/286 Sequence Identity: 24% (88 aa) MNKWINGELSNFNYLMILNHLAHRHIGDPMNHPVLPWVI-DFTTSPINIDNDNDSRDDVDNSSSSNNNNNNNNEDQ--SGKTVGWRDLTK------TKYR ..||.||..||| |||.|| .. | |....|| |||| |.|.. ...| | . . .|||.| .. | TEKWQNGQISNFEYLMWLNIFSGRSFNDLSQYPVFPWVISDYTSE-TTLD------------------------DLNGN-DPSTYRDLSKPMGAQMNEER LNKGDEQLDFQFFNTGNSTTLGDDSMGGGIGSIGSTGGITNSSNNGGGGGSGNSGKAHHISDILSELTYYSYLARRTSVP--LLRRFVRTNY--EPNEYP |.| .|.... . .| . |. | . .. ..|| | | | . . |... LQKFKERYKE-MDDMG---------------------------------------PFHYGSHYSCPMIVCHYLIR--MEPFTTLHIDLQGGKFDHPDRLF ATMERLYRWTP--------DECIPEFFTDSTIFKSIHS-----------DMPDLQLPDWVPNQSTQEFIKIHMNALESDHVSKQLHSWIDLTFGYLLSGE .|....... .|.|||||.. .|| .. .. | .|| | ..| ..|. .| |||||.||..|| |||| ||| .|. HSIEEAWNSCTNKNNMNDFRELIPEFFCCPEFFKNSNHFDFGRQDGKEGKVDDVELPPWC-HKSPYDFVYKHRKALESDYVSQHLHHWIDLIFGYKQRGK EAIKAKNL-------------ALMD--------TTIPRNNGIV--QLFNHPHPKK |||.|.|. .. | .. .| | . |||. |||.. EAIEANNVFHPLTYEDIWDLDNINDDPMEREAIEAQIHNFGQCPQQLFTKPHPQR |
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| Kinase | LvsG.AA | Ciliate-E2 | 1307-1400 | 13 | 2.5e-10 | 31.64 | In-house | 275-365 (365) | Show / Hide |
Range on Protein: 1307-1400
Range on HMM: 275-365/365
Sequence Identity: 13% (15 aa)
KSNDMFALGCIIAELYQGYPLFTSKGLENHFLNHSNSSNNNNNNNNNNNNNNKNGSFM--------------ITSNLPNNVKEIVDK----LIQPNPMER
.. |...||.|. |. |.| | ... ... . .. .. ......| . | ..| .| .|
YKCDIWSLGVILYEMLFGKPPF----------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR
SE-VNELLSSSLF
...| |
ITGWEQILNHPWF
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| Kinase | LvsG.AA | CMGC-Unique | 1296-1406 | 33 | 2.1e-08 | 25.13 | In-house | 181-290 (352) | Show / Hide |
Range on Protein: 1296-1406 Range on HMM: 181-290/352 Sequence Identity: 33% (38 aa) NNKEQSNLEILKSNDMFALGCIIAELYQGYPLFTSKGLENHFLNHSNSSNNNNNNNNNNNNNNKNGSFMITSNLPNNVKEIVDKLIQP--NPMERSEVNE |. . |. .. |. || ..|||. |. || ||. |.| | | ||||||||...||||| . | .. |. | .. | | . .. . NHHKLSYRIYWKKMDMWSAGCIFHEMIQGKQLFNNPNLDN---NNNNNNNNNNNNNNFHGNNNKNVIHNIVKFNGNHFKWDNNQNIDNNFNNWPEMMMQQ LLSSSLFPNYFKQ | .. || ... LMQFINFPVPWEK |
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| Kinase | LvsG.AA | DYRK2 | 1310-1328 | 73 | 9.8e-08 | 20.87 | In-house | 184-202 (318) | Show / Hide |
Range on Protein: 1310-1328 Range on HMM: 184-202/318 Sequence Identity: 73% (14 aa) DMFALGCIIAELYQGYPLF || .|||.|||| ||||| DMWSFGCIMAELYTGYPLF |
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| Kinase | LvsG.AA | CMGC | 1310-1328 | 44 | 3.3e-07 | 18.73 | In-house | 458-484 (513) | Show / Hide |
Range on Protein: 1310-1328 Range on HMM: 458-484/513 Sequence Identity: 44% (12 aa) DMFALGCIIAELYQG--------YPLF || ..|||.||.|.| .||| DMWSVGCIFAEMYTGYQSLIFRGKPLF |
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| Kinase | LvsG.AA | PLK1 | 1310-1400 | 20 | 1e-06 | 17.4 | In-house | 181-253 (253) | Show / Hide |
Range on Protein: 1310-1400 Range on HMM: 181-253/253 Sequence Identity: 20% (19 aa) DMFALGCIIAELYQGYPLFTSKGLENHFLNHSNSSNNNNNNNNNNNNNNKNGSFMITSNLPNNVKEIVDKLIQPNPMERSEVNELLSSSLF |....|||. | | | | .| |.. .. |. ..| |.. . .... |...|.| .| .....|. | DIWSIGCIMYILLFGQPPFETKCLKETYSRI------------------KKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF |
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| Kinase | LvsG.AA | CDKL | 1310-1328 | 47 | 0.00011 | 11.95 | In-house | 182-200 (286) | Show / Hide |
Range on Protein: 1310-1328 Range on HMM: 182-200/286 Sequence Identity: 47% (9 aa) DMFALGCIIAELYQGYPLF |. |.||..||. .| ||. DIWAIGCVMAEMIDGQPLW |
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| Kinase | LvsG.AA | ERK7 | 1310-1328 | 47 | 0.000545 | 9.18 | In-house | 189-207 (292) | Show / Hide |
Range on Protein: 1310-1328 Range on HMM: 189-207/292 Sequence Identity: 47% (9 aa) DMFALGCIIAELYQGYPLF || .|||..|. .| |.| DMWSIGCILGEMLRGKPMF |
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| Kinase | LvsG.AA | CDC2 | 1310-1328 | 45 | 0.001733 | 6.0 | In-house | 188-209 (301) | Show / Hide |
Range on Protein: 1310-1328 Range on HMM: 188-209/301 Sequence Identity: 45% (10 aa) DMFALGCIIAEL---YQGYPLF || ..|||.||. . ||| DMWSIGCIFAEMFMDVTKKPLF |
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| Kinase | LvsG.AA | Dicty3 | 1368-1395 | 25 | 0.005258 | 5.54 | In-house | 324-351 (351) | Show / Hide |
Range on Protein: 1368-1395 Range on HMM: 324-351/351 Sequence Identity: 25% (7 aa) NLPNNVKEIVDKLIQPNPMERSEVNELL ...|. |.. . | .| |. ..||. HVSNFCKNFIQHCWQIDPNHRWDMHELI |
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| Kinase | LvsG.AA | Pkinase | 1310-1336 | 29 | 0.023652 | 9.4 | Pfam | 194-223 (293) | Show / Hide |
Range on Protein: 1310-1336 Range on HMM: 194-223/293 Sequence Identity: 29% (9 aa) DMFALGCIIAELYQGYPLFTSK----GLENH ||...|||..|.. |.|.| .. . .. DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQ |
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| Kinase | LvsG.AA | Pkinase | 1368-1400 | 18 | 0.030491 | 9.01 | Pfam | 261-293 (293) | Show / Hide |
Range on Protein: 1368-1400 Range on HMM: 261-293/293 Sequence Identity: 18% (6 aa) NLPNNVKEIVDKLIQPNPMERSEVNELLSSSLF |.. . |..........| .| ..| . | NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | LvsG.AA | CDKL | 1376-1400 | 24 | 0.03505 | 3.26 | In-house | 262-286 (286) | Show / Hide |
Range on Protein: 1376-1400 Range on HMM: 262-286/286 Sequence Identity: 24% (6 aa) IVDKLIQPNPMERSEVNELLSSSLF .. |. . .| || . .|.....| FMKKCLHMDPDERMTCEQLMHHPYF |
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| Kinase | LvsG.AA | CMGC | 1331-1400 | 18 | 0.124585 | 0.08 | In-house | 438-513 (513) | Show / Hide |
Range on Protein: 1331-1400 Range on HMM: 438-513/513 Sequence Identity: 18% (15 aa) KGLENHFLNHSNSSNNNNNNNNNNNNNNKNGS-FMITSN----------LPNNVKEIVDKLIQPNPMERSEVNELLSSSLF | ..| | .|.| .. | |.. .... |. .. . . |. .. . ..|. | .| .| . . |. | KPWKNLFPWHPNWDD-N-NKK-AMVF-NW-IYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF |
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| WD40 | LvsG.AA | WD40 | 1856-1894 | 22 | 1.9e-12 | 38.41 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 1856-1894 Range on HMM: 1-39/39 Sequence Identity: 22% (9 aa) GNIVAQYKEHNASIKSLAVSPS-EERFISGSKDNLVKIWS .. .. . .|.... ..|..|. ...||| |. ..||. WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 1855-1894 | 20 | 3.1e-10 | 41.26 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1855-1894 Range on HMM: 1-46/46 Sequence Identity: 20% (10 aa) QGNIVAQYKEHNA--SIKSLAVSPSE------ERFISGSKDNLVKIWS . . |. .| |.. .. .....|. ....||| |. ..||. T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 1898-1933 | 22 | 0.031045 | 9.05 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 1898-1933 Range on HMM: 1-39/39 Sequence Identity: 22% (9 aa) TKSLTTYNQHMHTAHTVHFVSS---LVASCDI-TSIQVWD | ..|. | |. . .. . ..||. .| .|| WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 1897-1933 | 18 | 0.042784 | 9.0 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1897-1933 Range on HMM: 1-46/46 Sequence Identity: 18% (9 aa) STKSLTTYNQHMH--TAHTVHFVSS--------LVASCDITS-IQVWD . | . |.. | . ..| . .. ..||.. . | .|| T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 1936-1974 | 18 | 0.33241 | 3.38 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1936-1974 Range on HMM: 1-46/46 Sequence Identity: 18% (9 aa) SKIKVNVFYEPTG--SFSCFEPISS-------KYLIASTCESTLSFYD . | .| || . .| .. .||... .|. ..| T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 1937-1974 | 17 | 8.606949 | 2.02 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 1937-1974 Range on HMM: 1-39/39 Sequence Identity: 17% (7 aa) KIKVNVFYEPTGSFSCFEPISS-KYLIASTCE-STLSFYD . . .| . |.. .| . ..|| .. .|. .| WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 1994-2039 | 19 | 0.275867 | 6.32 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 1994-2039 Range on HMM: 1-39/39 Sequence Identity: 19% (9 aa) IRCIATSNDHLIGSNSNQFSSSSFIASATPTWVATGSSSGMITLLD |..| | . .. .. . ....|.|| | | . | WKCKHTF-GHTHWVTCCAWHPD------MGHYLASGSRDGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 1977-2039 | 15 | 0.356264 | 3.19 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 1977-2039 Range on HMM: 1-46/46 Sequence Identity: 15% (10 aa) MGSLTHEWSLAYQTGQ--AIRCIATSNDHLIGSNSNQFSSSSFIASATPTWVATGSSSGMITLLD ...|... . ...|.. . |. . |...|.|| | | . | T-KCVHTFK---GHTGNSWVTCVCWHPDGGSD--------------DYPNYLASGS-DGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 2042-2080 | 20 | 0.00179 | 17.7 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 2042-2080 Range on HMM: 1-46/46 Sequence Identity: 20% (10 aa) TGTILEQWKSHHDS--PVNKLIAQGS-------RYLISCGDKSVIQWD | . . .| |.. .|. . . .||.|..|... || T-KCVHTFK-GHTGNSWVTCVCWHPDGGSDDYPNYLASGSDGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 2043-2080 | 17 | 0.258761 | 6.4 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 2043-2080 Range on HMM: 1-39/39 Sequence Identity: 17% (7 aa) GTILEQWKSHHDSPVNKLIAQGS--RYLISCGD-KSVIQWD .. . .| ..|. . . .||.|... ... || WKCKHTF--GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 2142-2179 | 18 | 0.022349 | 10.78 | SMART | 1-46 (46) | Show / Hide |
Range on Protein: 2142-2179 Range on HMM: 1-46/46 Sequence Identity: 18% (9 aa) DGLKLNTPK--QS--NILSLSFFPLH------HVLLAGTDDGFIKICQ . . | | .. ...... | . ..|..| || |.| T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD |
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| WD40 | LvsG.AA | WD40 | 2151-2179 | 26 | 0.793242 | 5.0 | Pfam | 10-39 (39) | Show / Hide |
Range on Protein: 2151-2179 Range on HMM: 10-39/39 Sequence Identity: 26% (8 aa) QSNILSLSFFPL-HHVLLAGTDDGFIKICQ .. . .... | |.|. | .|| |.| THWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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