Gene IrlF (Slime mold)

IrlF

Species: Slime mold
Alias: DdisK097, DDB0229362, IrlF
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: IRE

Sequence

Name Sequence Type Origin Length Description Download
IrlF.AA Protein None 1400 None Fasta, JSON
IrlF.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of IrlF.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IrlF.AA IRE 953-1235 49 2.3e-170 572.24 In-house 1-292 (292) Show / Hide 
Range on Protein: 953-1235
Range on HMM: 1-292/292
Sequence Identity: 49% (156 aa)

SNILGRGSNGTLVFKGIWSDKIPVAIKQMQKAFNPLINKEVEALITLTNKNCSNMIRYIDKEEDKHFVYLGLTLCDVSLQYLVENGKLNEFINSSGKS--
.||||||.||||||||||...||||.|||||.|||.|..|...||.|...|..|.|||...|||..||||.|.||. |||..||..|.|.|||||..|  
NNILGRGCNGTLVFKGIWNGRIPVAVKQMQKEFNPFISREIQMLIKLESDNHPNVIRYYCQEEDDQFVYLALELCQGSLQDYVEQKKRNNFINSSNNSNN

-----------------LNELAKDIINGVQFLHSHDIVHNDLNPRNILTLSTNKNNNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSKMEVESSY
                 ...|.|...||.|.|||..|||.||.|.|||.  ..   .|...                  .||.|.|||.||.||.||..|
NNKNNNNNNNQWQIHIRMWQLIKQCMNGLQHLHSQNIVHRDLKPHNILIHMNR---PNQHG------------------ENNRFMISDFGLCKMLVEGRY

SFTTNV---PTGQGGYHPVEVLQS---KRMTKSVDIFSLGCILFYLFTNGQHPFGNDKLFRIYNIMLNKVNLELLG-HNLLA----CDLIKSMISNDESK
|||.|.   |||..|.||.|.||.   ||.||||||||.||...|..||||||||||||.|..||. .|.||. |  ||...    ||||..||..|..|
SFTRNIRSGPTGTWGWHPPEMLQEFCQKRKTKSVDIFSMGCVFYYVMTNGQHPFGNDKLHRQANILKGKYNLDQLKHHNHWHIVIACDLIHQMIHHDPQK

RPTIENVLNHPLF
||||...||||.|
RPTIKECLNHPFF
Kinase IrlF.AA Pkinase 950-1235 21 6.2e-29 103.39 Pfam 1-293 (293) Show / Hide 
Range on Protein: 950-1235
Range on HMM: 1-293/293
Sequence Identity: 21% (72 aa)

RNESNILGRGSNGTLVFKGIWSDK-IPVAIKQMQKAFNPLINK-------EVEALITLTNKNCSNMIRYIDKEEDKHFVYLGLTLCDV-----SLQYLVE
     ..|.|| |. |.|... .  . ||.|.. |  .    .       |.. .  | |  . | .|..|  |||  .|. . .|.      .|  ...
YHIGRKIGSGSFGC-VYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

---NGKL--NEFINSSGKSLNELAKDIINGVQFLHSHDIVHNDLNPRNILTLSTNKNNNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSK-MEVE
   .|..   |        .   .. |. |....||. |.| || | |||  ... ..                          .. |.| ||.| .. .
TWRHGCFYFSEWE------CKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-------------------------CVKICDFGLAKQFD-Y

SSYSFTTNVPTGQGGYHPVEVLQ-SKRMTKSVDIFSLGCILFYLFTNGQHPFGND-------KLFRIYNIMLNKVNLELLGHN-----------------
 ..|  .....|  .| . ||.. ..  ...||..|.||||..... |. || ..       ....|..||  ..  .    .                 
-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFH

---LLACDLIKSMISNDESKRPTIENVLNHPLF
     ..|.||...  | .||||.| .|.|| |
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase IrlF.AA Ciliate-E2 950-1235 17 1.4e-27 91.69 In-house 1-365 (365) Show / Hide 
Range on Protein: 950-1235
Range on HMM: 1-365/365
Sequence Identity: 17% (70 aa)

RNESNILGRGSNGTLVFKGIWSDKIPVA----------------IKQMQKAFNPLINKEVEALITLTNKN--------------------CSNMIRYIDK
 .  ...|.|. |.      |...  .|                 |....| . ......|..    . .                    . | |.... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

EE--DKHFVYLGLTLCDV-SLQYLVENGKLNEF----------INSSGKSLNELAK-----------DIINGVQFLHSHD-IVHNDLNPRNILTLSTNKN
 .  |.. .|| . .|.  .|... .| |....          ..  ..   ....            || ....|||   |.| |. | |||       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

NNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSK-----------------------MEVESSYS------FTTNVPTGQGGYHPVEVLQ------
                              |.|.||||                       ... ..|.      ...|   |  || . |.|.      
----------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDN

---SKRMTKSVDIFSLGCILFYLFTNGQHPFGNDKLFRIYNIMLNKVNLE-----------------LLGHNLLACDLIKS----MISNDESKRPT-IEN
   .|. ....||.|||.||... . |..||       . .|. .|...                   . . . . ||||     |.  |..||.| .| 
QQKQKGYDYKCDIWSLGVILYEMLF-GKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQ

VLNHPLF
.|||| |
ILNHPWF
Kinase IrlF.AA CAMK 955-1235 18 3.8e-22 67.51 In-house 1-425 (425) Show / Hide 
Range on Protein: 955-1235
Range on HMM: 1-425/425
Sequence Identity: 18% (82 aa)

ILGRGSNGTLVFKGIWS-DK------------IPVAIKQMQK------------------------------AFN-PLINKEVEALITLTNKN----CSN
.||||| |. |...|   ..              |||| . |                              ...   . .|.| . .| ...      |
TLGRGSFGK-VKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

MIRYIDKEEDKHF-------------------VYLGL---TLCDVS------LQYLVENGKLNEF-----INSSGKSLNELA-----KDIINGVQFLHSH
 |. ..  ||.|.                   .|. .    .|.        ..|.||.|.  |      |  . . ..|       . |. .|...|||
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

DIVHNDLNPRNILTLSTNKNNN--------NNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSKMEVESSYSF---------------------TTNV
.||| || | |||  . |....                             ..||   |.| |....  ... .|                       . 
NIVHRDLKPENILLDDNNDDSDPVEHDEIFD--------------------WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKT

PTGQGGYHP-VEVLQSKR--------------MTKSVDIFSLGCILFYLFTNGQHPFGNDKLFRIYN------------IMLNKVNLELLGHNLL-----
. |  .| .  |||..|.               ....|. |.|.||. . . |  ||  |.  .|..             .  | . .   . .      
FCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLC-GYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCN

--------------------ACDLIKSMISNDESKRPTIENVLNHPLF
                    . |||..|   | .||.||| .|||| .
YGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase IrlF.AA Ciliate-E2-Unclassified 946-1235 16 5.1e-22 73.19 In-house 1-352 (352) Show / Hide 
Range on Protein: 946-1235
Range on HMM: 1-352/352
Sequence Identity: 16% (65 aa)

FKFNRNESNILGRGSNGTLVFKGIWSDK--------IPVAIKQMQKAFNPLINKEVEALITLTNKN-------------------CSNMIRYIDKEEDKH
.|...    ..|.|..|. |.| . ...        . ......||  .  .  ..  .... ||.                   . . ..... ..|| 
YKIIK----QIGQGGFGK-VYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ

FVYLGLTLCDVS--LQYLVENGK-------------------LNEFI---NSSGKSLNELAKDIINGVQFLHSHD-IVHNDLNPRNILTLSTNKNNNNNN
 .|. . .|.    .||. ...|                    .. .            ... |..| ..||.   |.| |. | |||  . .|      
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKA------KFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK------

KSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSK--MEVESSYSFT------------TNVPTGQGGYH----PVEVLQSKRMT----KSVDIFSLGCILF
                    |.   |.|.|.||   . . .. ..            ..  .|  .|     . ||||..       ...||.|||.||.
--------------------NYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILY

YLFTNGQHPFGNDKLFR----------------IYNIMLNK---VNLELL-----GHNLLACDLIK----SMISNDESKRPTIENVLNHPLF
.. ..  .||.  .                   .|.. ..|   .. .       . .  | |.|.    .|. .. .||.|.| .||||.|
EMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase IrlF.AA S_TKc 950-1235 20 1.1e-21 79.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 950-1235
Range on HMM: 1-231/231
Sequence Identity: 20% (63 aa)

RNESNILGRGSNGTLVFKGIWSD-KIPVAIKQMQKAFNPLINKEVEALITLTNKNCSNMIRYIDKEEDKHFVYLGLTLCDV---SLQYLVENGK------
    ...|.|. |. |.|... . .  ||||..       | .|.. |      .. | ....|  .| ...|. . .||    .|  . .. .      
YEILRKIGKGAFGK-VYKCRHKKTGRIVAIKIIK----EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LNEFINSSGKSLNELAKDIINGVQFLHSHDIVHNDLNPRNILTLSTNKNNNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSKMEVESSYSFTTN
 ..|           ... |.......||| |.| || | |||  .                                  |.| ||..           .
PFPE-H------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------------------------HIKICDFGLARQL---------T

VPTGQGGYHPVEVLQSKRMTK-SVDIFSLGCILFYLFTNGQHPFGNDKLFRIYNIMLNKVNLELLGHNLLACDLIKSMISNDESKRPTIENVLN------
   |   | . |||     .| ..|. |.||||. ... |. ||    .........             |.|.|. .   | .||||.  .|.      
TFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPLF
 || |
CHPWF
Kinase IrlF.AA ULK 950-1081 25 7e-19 62.61 In-house 21-182 (329) Show / Hide 
Range on Protein: 950-1081
Range on HMM: 21-182/329
Sequence Identity: 25% (42 aa)

RNESNILGRGSNGTLVFKGIWSDK-----IPVAIKQMQ---KAFNP----------LINKEVEALITLT----NKN-CSNMIRYIDKEEDKHF--VYLGL
 . ...|| || |  |.||.  ..     . ||.|...   .  ..          |...|.. . .|     .|| . | ....|  |....  .|. .
YCLNHCLGKGSFG-KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

TLCDV-SLQ-YLVENGKLNEFI----NSSGKSLNELAKDIINGVQFLHSHDIVHNDLNPRNIL
 .|.   |. |. .|.||.|      . | .   .  |.|.|| ..||.| |.| |. | |||
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNIL
Kinase IrlF.AA TKL 1054-1233 18 5.5e-18 61.37 In-house 137-364 (364) Show / Hide 
Range on Protein: 1054-1233
Range on HMM: 137-364/364
Sequence Identity: 18% (44 aa)

LAKDIINGVQFLHSHD--------IVHNDLNPRNILTLSTNKNNNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSKMEVES--------------
.|.||  |...|||..        |.| ||...|||  . ..|.. |      .          | |..    |.|.|||..  .|              
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NYM----Y----------NPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESA

---SYSFTTNVPTGQGGYHPVEVLQSK----------------RMTKSVDIFSLGCILFYLFTNGQHPFG-NDKLFRI---------YNIMLNKVNLELL
   ... ||. . |  .. . |||. .                  ....|..| | .|. ..|  . |.  ..   .|         . . ...  ... 
EHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIP

GHNL--------LAC-----DLIKSMISNDESKRPTIENVLNHP
 . .          |     .|..   . | .|||. . .| . 
PIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IrlF.AA ULK 950-1081 26 9.5e-18 59.61 In-house 34-191 (324) Show / Hide 
Range on Protein: 950-1081
Range on HMM: 34-191/324
Sequence Identity: 26% (42 aa)

RNESNILGRGSNGTLVFKGIWSDK----IPVAIKQMQKA-FNP------------LINKEVEALITLT---NKNCSNMIRYIDKEEDKHF--VYLGLTLC
 . ...|| || |  |.||.  ..      ||.|...|  .|             |...|.. . .|    ..|. . ....|  |....  .|. . .|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

DV-SLQ-YLVENGKLNEFI----NSSGKSLNELAKDIINGVQFLHSHDIVHNDLNPRNIL
.   |. |. .|.||.|      . | .   .  |.|.|| ..||.| |.| |. | |||
NGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNIL
Kinase IrlF.AA WEE 1054-1178 24 3e-13 40.87 In-house 116-234 (297) Show / Hide 
Range on Protein: 1054-1178
Range on HMM: 116-234/297
Sequence Identity: 24% (33 aa)

LAKDIINGVQFLHSH-DIVHNDLNPRNILTLSTN--------KNNNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSKMEVESSYSFTTNVPTGQG
.  ||..|....||. ..||.|. | ||.  .           . |||.                   .|. . | |.|..  ...|  . ...   | .
ILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDW----------------W-FNMMCKIGDFGHV-TDMNSNNNNPHQEQEGDS

GYHPVEVLQ-SKRMTKS--VDIFSLGCILFYLFTNGQ
 | . |.||  ...|..   ||||||. .. | .| .
RYMAPEILQGYYHYTHLYKADIFSLGITIYELACNMD
Kinase IrlF.AA CMGC 950-1193 15 4.3e-12 35.1 In-house 1-370 (513) Show / Hide 
Range on Protein: 950-1193
Range on HMM: 1-370/513
Sequence Identity: 15% (60 aa)

RNESNILGRGSNGTLVFKGIW---------------SDKIPVAIKQMQKAFNPLINK--------------EVEALITL----------------TNKN-
    . .|.|. |  |.|..                 ..  |||| . ..|..   |              |.. |  |                 ..| 
YEIIKKIGEGTYG-VVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CSNMIRYIDKEEDK--------------HFVYLGLTLCDVSLQYLVENGK----------LNEFI---NSSGKSLNE----------LA------KDIIN
. ... ..  ....                .||   ..| .|  . .| .          |.|             .          .       . |..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKH-------PHRRPPHNIKYFMIHIRYMYQILR

GVQ--FLHSHD--IVHNDLNPRNILTLSTNKN---------NNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSKMEVES----------------
|.   ..|||.  |.| || | |||  .....         . . |.                 ..|    | | ||.. . .                 
GLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSED-W-NPC----------------QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVN

-----SYSFTTNVPTGQGGYHPVEVLQSKRM----------TKSVDIFSLGCILFYLFTN-------GQHPFG---------------NDKLFRIYNIM
     .  .|..| |    | . |.| . .           |...|. |.|||.. ..|.       |.  |                 | ||.| ...
KDDKPNRPYTHYVVTRW--YRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVL
Kinase IrlF.AA AGC 1058-1171 17 5.6e-10 20.47 In-house 162-296 (395) Show / Hide 
Range on Protein: 1058-1171
Range on HMM: 162-296/395
Sequence Identity: 17% (28 aa)

IINGVQFLHS-HDIVHND-LNPRNIL------------------------------TLSTNKNNNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLS
|. ....||| ..|.| | | | |||                              . .....  |... . |.  |.. . |           . ....
IVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSN-MKFHW-HNKKY-Q-KS--NMD-T-N-----------K-CNPN

KMEVESSYS----------FTTNVPTG--QGGYHPVEVLQSKRMTKSVDIFS--LGCILF
..  .  .|          ..|.   |     | . |.|     .|..|. |  |||...
NWQRNN-MSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY
Kinase IrlF.AA TyrKc 950-1235 18 6.3e-10 -62.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 950-1235
Range on HMM: 1-280/280
Sequence Identity: 18% (59 aa)

RNESNILGRGSNGTLVFKGIWSDKIPVAIKQMQ-KAFNPLINKEVEALITL--TNKNCSNMIRYIDKEEDKHFVYLGLTLCDVSLQYLVENGKLNEFINS
     .||.|  |. |.||.|.  |.||.| ..  |    . .| . .  |   ..|  ... .. ... . |.| .  .    .  ....| |.... .
ITLGKKLGEGAFGE-VYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMI---VMEYMPHGDLKDYLRK

SG-----KSLNELAKDIINGVQFLHSHDIVHNDLNPRNILTLSTNKNNNNNNKSNNKIKSNNNSNNNSNNNSNNSFIISDLGLSKMEVES--------SY
..     | | . . .| .| ..|||. ..| ||  ||.| .. |.                               ||| |||.   .          |
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL-VGENH----------------------------TVKISDFGLSRDIYDDDQQGESKDYY

SF----TTN--VPTGQGGYHPVEVLQSKRMTKSVDIFSLGCILFYLFTNGQHPFGN-----DKLFRIYNIMLNK--VNLELL--------GHNLLACDLI
.      ..  .|       . |... .. |   |..| |  .. .||.|| |  .      . .....   .                  .  .   ..
RKKEHKGGKTMLPI---RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IM

KSMISNDESKRPTIENVLNHPLF
|.    | ..||| ...  | .|
KQCWHEDPEDRPTFSEI--HECF
Kinase IrlF.AA ULK 1150-1235 25 1e-09 30.15 In-house 221-329 (329) Show / Hide 
Range on Protein: 1150-1235
Range on HMM: 221-329/329
Sequence Identity: 25% (28 aa)

EVLQSK--RMTKS---VDIFSLGCILFYLFTNGQHPFGNDKLFRIY-NIMLNKVNL----------ELLGHN---------LLACDLIKSMISNDESKRP
..||..  ..  .   .||.|||||.... . |. || .   .  | .|. . .|.          . |  .             |||. |.  ||..| 
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLY-GKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRI

TIENVLNHPLF
..| ..|||.|
SWEELFNHPWF
Kinase IrlF.AA ULK 1150-1235 23 3.7e-09 28.69 In-house 217-324 (324) Show / Hide 
Range on Protein: 1150-1235
Range on HMM: 217-324/324
Sequence Identity: 23% (26 aa)

EVLQSK--RMTKS---VDIFSLGCILFYLFTNGQHPFGNDKLFRIY-------------NIMLNKVNLELL------GHNLLACDLIKSMISNDESKRPT
..||..  ..  .   .||.|||||.... . |. || ..     |              |. .. ...               |||. |.  ||..| .
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLY-GKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRIS

IENVLNHPLF
.| ..|||.|
WEEIFNHPWF
Kinase IrlF.AA AGC 1208-1235 34 3.6e-07 13.05 In-house 358-395 (395) Show / Hide 
Range on Protein: 1208-1235
Range on HMM: 358-395/395
Sequence Identity: 34% (13 aa)

ACDLIKSMISNDESKRPT----------IENVLNHPLF
| |||| ..  | .||..          .| . ||| |
AKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase IrlF.AA WEE 1210-1235 42 1.6e-05 14.54 In-house 272-297 (297) Show / Hide 
Range on Protein: 1210-1235
Range on HMM: 272-297/297
Sequence Identity: 42% (11 aa)

DLIKSMISNDESKRPTIENVLNHPLF
.|||.|.  | ..|||..  |.||. 
QLIKWMMHPDPEQRPTCQQLLQHPVL
Kinase IrlF.AA CMGC 1207-1235 48 2.4e-05 12.5 In-house 485-513 (513) Show / Hide 
Range on Protein: 1207-1235
Range on HMM: 485-513/513
Sequence Identity: 48% (14 aa)

LACDLIKSMISNDESKRPTIENVLNHPLF
.| ||.| |   | .||.|.|  |.|| |
QAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase IrlF.AA TKL 956-981 28 0.000634 10.03 In-house 33-66 (364) Show / Hide 
Range on Protein: 956-981
Range on HMM: 33-66/364
Sequence Identity: 28% (10 aa)

LGRGSNGTLVFKGIWSD---------KIPVAIKQM
.|.|. |  |.||.|             .||.|..
IGSGGFG-EVYKGKWRGWGGKCPSDTGKDVAVKKF