Gene IrlD (Slime mold)

IrlD

Species: Slime mold
Alias: DdisK095, IrlD, DDB0231221
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: IRE

Sequence

Name Sequence Type Origin Length Description Download
IrlD.AA Protein None 1505 None Fasta, JSON
IrlD.kin_dom Protein Kinase Domain None 273 None Fasta, JSON

Protein domain

Protein domains of IrlD.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IrlD.AA IRE 1057-1324 54 4.8e-179 601.12 In-house 1-292 (292) Show / Hide 
Range on Protein: 1057-1324
Range on HMM: 1-292/292
Sequence Identity: 54% (159 aa)

EFIIGRGSNGTLVFKGIWNDRIPVAIKQMHKAFNPLISKEIEVLITLTNKNCNNIVRYIDQEEDDMFVYLGLTLCNGSLQNLVEKDLEINLISTSNNENN
. |.|||.|||||||||||.|||||.|||.|.|||.||.||..||.|...|..|..||..|||||.||||.|.||.||||..||.....|.|..|||.||
NNILGRGCNGTLVFKGIWNGRIPVAVKQMQKEFNPFISREIQMLIKLESDNHPNVIRYYCQEEDDQFVYLALELCQGSLQDYVEQKKRNNFINSSNNSNN

NNNKLKNFIGSEL---RLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDR---------FIISDLGLSKMEVTSSYSFTMHA---PTGQEGFHPAEV
||....|.. . .   |...|||....|.|.||.|.|||.||.|.||||...|         |.|||.||.||.|...||||...   |||..|.||.|.
NNKNNNNNNNQWQIHIRMWQLIKQCMNGLQHLHSQNIVHRDLKPHNILIHMNRPNQHGENNRFMISDFGLCKMLVEGRYSFTRNIRSGPTGTWGWHPPEM

LLE---KRKTKSVDIFSMGCILFYLMTGGQHPFG-DKFFRMANILTDKPILEPLK-HNLVA----CDLISQMISKNESDRPTTENILLHPFF
|.|   ||||||||||||||...|.||.|||||| ||..|.||||..|..|..|| ||...    ||||.|||......||| ...| ||||
LQEFCQKRKTKSVDIFSMGCVFYYVMTNGQHPFGNDKLHRQANILKGKYNLDQLKHHNHWHIVIACDLIHQMIHHDPQKRPTIKECLNHPFF
Kinase IrlD.AA Pkinase 1054-1324 24 2.6e-34 122.38 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1054-1324
Range on HMM: 1-293/293
Sequence Identity: 24% (78 aa)

RKDEFIIGRGSNGTLVFKGIWNDR-IPVAIKQMHKAFNPLISK--------EIEVLITLTNKNCNNIVRYIDQEEDDMFVYLGLTLCNG-----SLQNLV
 . . .||.|| |. |.|... .  . ||.|.. |  .   .|        ||...  | |  . ||||..|  ||.  .|. . .|.|     .|  ..
YHIGRKIGSGSFGC-VYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-N--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

EKDLEINLISTSNNENNNNNKLKNFIGSELRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDRFI-----ISDLGLSK-MEVTSSYSFTMHAPTGQ
.                   . ..|..||  .   .. |. |....|..||.| || | ||||...  |     |.| ||.| .. . ..|  |. ..| 
ST-----------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS--MTTFCGT

EGFHPAEVLL-EKRKTKSVDIFSMGCILFYLMTGGQHPFG--------DKFFRMANILTDKPILEPLKHN--------------------LVACDLISQM
 .. . ||..  .  ...||..|.||||..... |. ||         |. .....|.  ..  .  . .                      ..|.|. .
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

ISKNESDRPTTENILLHPFF
. |. ..||| | || ||.|
LCKDPKKRPTAEQILQHPWF
Kinase IrlD.AA Ciliate-E2 855-1324 12 8.4e-32 106.43 In-house 56-365 (365) Show / Hide 
Range on Protein: 855-1324
Range on HMM: 56-365/365
Sequence Identity: 12% (71 aa)

EKDLLEQEENEKKRLKEKRKKEEKEKKKQQNLKQKSLITNNTTTTTTTTPIPITVPIPTQTQTPTQTPTQTPIPTPIPTTPIPTTPIPIPIQLTPTTPKT
.|. .|| ..|.. ..|..  .                                                                              
KKNQIEQIKQEIHIMREINC-F------------------------------------------------------------------------------

PKTPKTPKTPTTPKTPITPKTPKNSTLDKQTISTPKTPPPLSVNTTPITPSPPPQTIATTITTTTTTPKTTKTTTTSKIPTLIIELNKYDISIGKFKFSR
                                                                                                    
----------------------------------------------------------------------------------------------------

KDEFIIGRGSNGTLVFKGIWNDRIPVAIKQMHKAFNPLISKEIEVLITLTNKNCNNIVRYIDQEE--DDMFVYLGLTLCNG-SLQNLVEKD-------LE
                                        | |. .  | . |..||.....  .  ||  .|| . .|.| .|. . ..        .|
--------------------------------------Y-KKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE

INLISTSNNENNNNNKLKNFIGSELRLLELIKDIVY---------------GIQFLHQQG-IVHNDLNPRNILIKDDRFIISDLGLSK------------
               . |.|  .|   ....| |..               ....||... |.| |. | |||.      |.|.||||            
-------------K-D-KYF--TEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHK

-----------MEVTSSYS------FTMHAPTGQEGFHPAEVLL---------EKRKTKSVDIFSMGCILFYLMTGGQHPFGDKFFRMANILTDKPILE-
           ...|..|.      .. .   |  |. . |.|          .|. ....||.|.|.||.....| ..||      . .|.  |  .  
QQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG-KPPF------QQQIKQCKIDFPC

----------------PLKHNLVACDLISQ----MISKNESDRPT-TENILLHPFF
                ..|. . . |||..    |. |... |.|  | || ||.|
PEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase IrlD.AA Ciliate-E2-Unclassified 1055-1324 17 6.9e-30 100.86 In-house 2-352 (352) Show / Hide 
Range on Protein: 1055-1324
Range on HMM: 2-352/352
Sequence Identity: 17% (66 aa)

KDEFIIGRGSNGTLVFKGIWNDR--------IPVAIKQMHKAFNPLISKEIEVLITLTNKN-------------------CNNIVRYIDQEEDDMFVYLG
|   .||.|..|. |.| . ..         . ...... |  .  .  ..  .... ||.                   . .||.......|.  .|. 
KIIKQIGQGGFGK-VYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LTLC-NGSLQNLVE-------------------KDLEINLIS---TSNNENNNNNKLKNFIGSELRLLELIKDIVYGIQFLHQQG-IVHNDLNPRNILIK
. .| .|.|..  .                   | .. . ..                         . ... |. |...||... |.| |. | |||..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKA---------------------KFYFAQILQGLEYLHHKNNIIHRDIKPENILFD

DD----RFIISDLGLSK--MEVTSSYSFT------------MHAPTGQEGFH----PAEVLLEKRKT----KSVDIFSMGCILFYLMTGGQHPFGD-KFF
..    .  |.|.|.||   .   .. ..            |.  .|  ..     . ||| ..       ...||.|.|.||.....|  .||.| .  
NNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCE

R----------------MANILTDKPILEPL--------KHNLVACDLIS----QMISKNESDRPTTENILLHPFF
                 . ..  .|.|  |         . .  | |.|.    .|. || . |.| | || ||.|
QHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase IrlD.AA CAMK 1059-1324 16 9.9e-28 85.84 In-house 1-425 (425) Show / Hide 
Range on Protein: 1059-1324
Range on HMM: 1-425/425
Sequence Identity: 16% (72 aa)

IIGRGSNGTLVFKGIWN-DR------------IPVAIKQMHK------------------------------AFN-PLISKEIEVLITLTNKN----CNN
..|||| |. |...|   .               |||| . |                              ...   . .|||.. .| ...      |
TLGRGSFGK-VKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

IVRYIDQEED-------------------DMFVYLGL---TLCNGS------LQNLVEK-------DLEINLISTSNNENNNNNKLKNFIGSELRLL---
|.. ..  ||                   |...|. .    .| |       .. .||.       |                   . .|  | . .   
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFD-------------------QFDIV-ERGRFTER

---ELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDD------------------RFIISDLGLSKMEVTSSYSF---------------------TMHAP
    ... |. .....|...||| || | |||. |.                     |.| |....   .. .|                      |. .
EARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTF

TGQEGFHP-AEVLLEKR--------------KTKSVDIFSMGCILFYLMTGGQHPFGDK---------------FFRMANILTDKP--ILEPLKH---NL
 |  .. .  |||. |.               ....|. |.|.||. . .|   || ..                  . .|.. |   . .....   | 
CGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCG-YPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCN-

V-------------------ACDLISQMISKNESDRPTTENILLHPFF
.                   . |||..|  .. ..|.| | .| ||..
YGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase IrlD.AA S_TKc 1054-1324 24 3.6e-25 90.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 1054-1324
Range on HMM: 1-231/231
Sequence Identity: 24% (68 aa)

RKDEFIIGRGSNGTLVFKGIWND-RIPVAIKQMHKAFNPLISKEIEVLITLTNKNCNNIVRYIDQEEDDMFVYLGLTLCNG---SLQNLVEKDLEINLIS
 .   .||.|. |. |.|.....    ||||...      | .||..|      .. |||...|  .|  ..|. . .|.|   .|  . .|     |  
YEILRKIGKGAFGK-VYKCRHKKTGRIVAIKIIK----EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL--

TSNNENNNNNKLKNFIGSELRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDRFIISDLGLSKMEVTSSYSFTMHAPTGQEGFHPAEVLLEKRKTK
             .|  .| .   ... |. .....|..||.| || | |||. . .  |.| ||..           .   |   . . |||     .|
-------------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGK

-SVDIFSMGCILFYLMTGGQHPFGDKFFRMANILTDKPILEPLKHNLVACDLISQMISKNESDRPTTENILL-------HPFF
 ..|. | ||||. ... |. ||    ..| ...              |.|.|...  |. ..|||   .|        ||.|
CKCDWWSCGCILYEMLC-GYPPFP-QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IrlD.AA TKL 1060-1322 14 4.2e-24 83.7 In-house 1-364 (364) Show / Hide 
Range on Protein: 1060-1322
Range on HMM: 1-364/364
Sequence Identity: 14% (58 aa)

IGRGSNGTLVFKGIWND---------RIPVAIKQMHKAFNPLI---------------------------SKEIEVLITLTNKNCNNIVRYID--QEEDD
||.|. |  |.||.|.            .||.|....  . .                             .|.|..  . . .. |||...   .....
IGSGGFG-EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

MF-----------VYLGLTLC-NGSLQNLVEKDLEINLISTSNNENNNNNKLKNFIGSELRLLELIKDIVYGIQFLHQQG--------IVHNDLNPRNIL
              ..   .| .||| ...                              ... ...||  |...||...        |.| ||...|||
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNIL

IKDD---------------RFIISDLGLSK-MEVTSSYSFTMHA----------------PTGQEGFHPAEVLLEK----------------RKTKSVDI
....               .  |.|.|||. |. ... . ||..                . |  .. . ||| ..                  ....|.
VDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDV

FSMGCILFYLMTGGQHPFG-DKFFRMA---------NILTD---KPILE---------PLKHNL--VACDLISQMISKNESDRPTTENILLHP
.|.| .|. ..|. . |.  .... |           .  |   .| .          .  ..     ..|. .  . . ..||. . || . 
YSFGIVLWEILTRCR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IrlD.AA ULK 1059-1217 22 1.3e-18 61.69 In-house 6-191 (329) Show / Hide 
Range on Protein: 1059-1217
Range on HMM: 6-191/329
Sequence Identity: 22% (46 aa)

IIGRGSNGTLVFKGIWNDR-----IPVAIKQMH---KAFNP----------LISKEIEVLITLT----NKN-CNNIVRYIDQEEDDMF--VYLGLTLCNG
..| || |  |.||. ...     . ||.|..    .  ..          |. .||... .|     .|| . |||...|  |.. .  .|. . .|||
CLGKGSFG-KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNG

-SLQNLVEKD-------LEINLISTSNNENNNNNKLKNFIGSELRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDD-------------RFIISDL
  |... .|.       .                  .. . ||   .. .|.|. | ..||...|.| |. | ||||...             .. |.| 
GDLEQYIKKNKKLPEDTE------------------EKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADF

GLSKM
|..|.
GFAKH
Kinase IrlD.AA STE 1054-1324 17 1.4e-17 58.75 In-house 1-359 (359) Show / Hide 
Range on Protein: 1054-1324
Range on HMM: 1-359/359
Sequence Identity: 17% (67 aa)

RKDEFIIGRGSNGTLVFKGIWND----------------RIPVAIKQMH--------------------KAFNPLISKEIEVLITLTNKNCNNIVRYIDQ
 ..  .||.|. || |.|.. ..                   .|||||.                    .     | |||...  . .  . |||.|.. 
WEGIEKIGKGAFGT-VYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGC

EEDD-------MFVYLGLTLCN-GSLQNLVEKDLEINLISTSNNENNNNNKLKNFIGSELRLLELIKDIVYG-IQFLHQQGIVHNDLNPRNILIKDDRFI
....         ... . ... |||  ....  ...   ..|.         ..  .|  .   ...|. |  ..||...|.| |. | |||.      
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQ------H-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VK

ISDLGLSKMEVTS--------------SYSFTMHAPTGQEGFHPAEVLLE------KRKTKSVDIFSMGCILFYLMTGGQHPFGD-KFFRMANILT----
..| |...  . |              . .      .|   .   ||..       |  . ..|| | || .  . | |..|. | . .|.    .    
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMAT-GKPPWHDMHPMRAMFMIPFNYH

-------------DKPILE------------------PLKHNLVACDLISQMISKNESDRPTTENILL--HPFF
             . | |.                  | |     .| |..   |. ..|||..  |   |||.
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase IrlD.AA ULK 1059-1217 22 3.2e-16 54.11 In-house 6-187 (324) Show / Hide 
Range on Protein: 1059-1217
Range on HMM: 6-187/324
Sequence Identity: 22% (46 aa)

IIGRGSNGTLVFKG--IWND--RIPVAIKQMHKA-FNP------------LISKEIEVLITLT---NKNCNNIVRYID-QEEDDM-FVYLGLTLCNG-SL
..| || |  |.||  . ..     ||.|.. |  .|             |. .||... .|    ..|. .||...| .|...  ..|. . .|||  |
CLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYCNGGDL

QNLVEKD------LEINLISTSNNENNNNNKLKNFIGSELRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDD-------------RFIISDLGLSK
... .|.      .                  .. . ||   .. .|.|. | ..||...|.| |. | ||||...             .. |.| |..|
EQYIKKNKKLPETE------------------EKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAK

M
.
H
Kinase IrlD.AA AGC 1240-1324 19 1.2e-15 35.44 In-house 277-395 (395) Show / Hide 
Range on Protein: 1240-1324
Range on HMM: 277-395/395
Sequence Identity: 19% (24 aa)

EVLLEKRKTKSVDIFS--MGCILFYLMTG-------G-----QHPFGDKFFRMANIL------TDKPILEP---------LKHNLVACDLISQMISKNES
|.|     .|..|. |  .||... ..||             . || ...  . .|.      ..|. . .          .    | |||.... |. .
EIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPE

DRPT----------TENILLHPFF
.|..          .| |  ||.|
KRLGCGGNDFGDKGAEEIKNHPWF
Kinase IrlD.AA TyrKc 1050-1324 18 3.1e-11 -41.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 1050-1324
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

FKFSRKDEFIIGRGSNGTLVFKGIWNDRIPVAIKQMH-KAFNPLISKEIEVLITL--TNKNCNNIVRYIDQE-----EDDMFVYLGLTLCNGSLQNLVEK
 .. .|    .|.|  |. |.||.|.  |.||.| ..  |    . .|....  |   ..|  ... .. |.     ...    .    ..|.|..   |
ITLGKK----LGEGAFGE-VYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

DLEINLISTSNNENNNNNKLKNFIGSELRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDR-FIISDLGLSKMEVTS--------SYSF----TMH
  .                      .   ||.   .|  | ..||.....| ||  ||.|.....   ||| |||.              |.       .
HRPK--------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

--------APTGQEGFHPAEVLLEKRKTKSVDIFSMGCILFYLMTGGQHPFGD------KFFRMANILTDKPILEPLKH----------NLVACDLISQM
        ||         |.. ... |   |..| |  .. ..| || |  .      . ... . . .   ... ..            .   ...| 
TMLPIRWMAP---------ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQC

ISKNESDRPTTENILLHPFF
   . .|||| ..|  | .|
WHEDPEDRPTFSEI--HECF
Kinase IrlD.AA ULK 1240-1324 21 4.1e-10 31.59 In-house 221-329 (329) Show / Hide 
Range on Protein: 1240-1324
Range on HMM: 221-329/329
Sequence Identity: 21% (24 aa)

EVLLEK--RKTKS---VDIFSMGCILFYLMTGGQHPFGDKFFRMA-----NILTDKPIL------EPLKHN---------LVACDLISQMISKNESDRPT
..| ..  .|  .   .||.|.|||.... .|   ...  |.        . . ..| .      .||. .             |||..|. ..|.|| .
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRIS

TENILLHPFF
 | .. ||.|
WEELFNHPWF
Kinase IrlD.AA RSK 1178-1266 27 1.3e-09 31.68 In-house 113-208 (278) Show / Hide 
Range on Protein: 1178-1266
Range on HMM: 113-208/278
Sequence Identity: 27% (27 aa)

IVYGIQFLHQQGIVHNDLNPRNILIKD----DRFIISDLGLSKMEVTSSYSFTMHAPTGQEGFHPAEVLLE--KRK--TKSVDIFSMGCILFYLMTG
||  ...||||||.| || | |||  |     .  ..| |..|     .... .. . .   . . |.| .  ...  .|..|..| |.... . ||
IVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTG
Kinase IrlD.AA ULK 1240-1324 22 1.4e-09 30.18 In-house 217-324 (324) Show / Hide 
Range on Protein: 1240-1324
Range on HMM: 217-324/324
Sequence Identity: 22% (25 aa)

EVLLEK--RKTKS---VDIFSMGCILFYLMTGGQHPFGDKFFRMA----NILTDK---PIL---EPLKHN---------LVACDLISQMISKNESDRPTT
..| ..  .|  .   .||.|.|||.... .|   .|.. |        . .  .   .|.   .|....             |||..|. ..|.|| . 
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISW

ENILLHPFF
| |. ||.|
EEIFNHPWF
Kinase IrlD.AA AGC 1178-1225 19 1.9e-09 19.06 In-house 162-265 (395) Show / Hide 
Range on Protein: 1178-1225
Range on HMM: 162-265/395
Sequence Identity: 19% (20 aa)

IVYGIQFLHQ-QGIVHND-LNPRNILIKDDRFI-ISDLGLSKMEVTS-----------------------------------------------------
|| ....||. .||.| | | | |||. .|  | ..| ||.|. ...                                                     
IVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDR

SYSF
 ..|
TWTF
Kinase IrlD.AA RSK 1299-1324 32 8e-07 21.37 In-house 248-278 (278) Show / Hide 
Range on Protein: 1299-1324
Range on HMM: 248-278/278
Sequence Identity: 32% (10 aa)

DLISQMISKNESDRPT-----TENILLHPFF
|||..|  .....|..     .| |. ||.|
DLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase IrlD.AA Pkinase_Tyr 1167-1228 25 0.001255 12.91 Pfam 109-171 (270) Show / Hide 
Range on Protein: 1167-1228
Range on HMM: 109-171/270
Sequence Identity: 25% (16 aa)

SELRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDRFI-ISDLGLSKME-VTSSYSFTMH
.  .||.   .|  | ..|......| ||  ||.|....... |.| ||..    .. | ....
TMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKR
Kinase IrlD.AA Pkinase_Tyr 1050-1085 34 0.015112 9.25 Pfam 1-36 (270) Show / Hide 
Range on Protein: 1050-1085
Range on HMM: 1-36/270
Sequence Identity: 34% (14 aa)

FKFSRKDEFIIGRGSNGTLVFKGIWN-----DRIPVAIKQM
 .| .|    .|.|. |. |.||.|.     ..||||.| .
ITFGKK----LGEGAFGE-VYKGTWKGDPDNTKIPVAVKML