Gene DDB0231281 (Slime mold)

DDB0231281

Species: Slime mold
Alias: DDB0231281, DdisK088
External Links: DictyBase Link ,
Annotation: Secondary Group: Other, Secondary Family: Dicty9

Classification

Group: Other
Family: Dicty9

Sequence

Name Sequence Type Origin Length Description Download
DDB0231281.AA Protein None 1592 None Fasta, JSON
DDB0231281.kin_dom Protein Kinase Domain None 330 None Fasta, JSON
DDB0231281.kin_dom2 Protein Kinase Domain None 174 None Fasta, JSON

Protein domain

Protein domains of DDB0231281.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0231281.AA Dicty9 16-344 50 1.5e-222 745.65 In-house 1-356 (356) Show / Hide 
Range on Protein: 16-344
Range on HMM: 1-356/356
Sequence Identity: 50% (182 aa)

ILNEINNNLEERLISIAKDKSGKLCVLKEIKYLNNKKKLEEFKKEEKNEEGIQKRIYQRNFNLEFNHLKNFSQMNHTSIIKYIEHIESKDEFGLVDRCIF
||.|||.|.|||...|.|.|||||||.|||.|.||..|..||.||..|.|.||...|.|||||||||.| ||.||.|..||..||||..||..|...||.
ILHEINDNNEERNVYIVKNKSGKLCVCKEIDYNNNNNKKDEFDKEKRNREYIQLKQYSRNFNLEFNHIK-FSHMNITKYIKHFEHIEQIDEWYLENKCIY

VTEYYEDGDLSSIK-------EIEFKDIINLFLKMLINLKEFQNVIIHRDIKPENIFLRKFKNNDGKVELDCYLGDYGSAQTLYTQNKS------TLIGT
..|||..||....|       |....|||..|.|||..|||||||||||||||||||.... ||||...|||.|.|.|..|..||.||.      |||||
IMEYYHGGDCNLLKINNDKCNEMDLFDIIYQFCKMLHILKEFQNVIIHRDIKPENIFFKRY-NNDGNIDLDCCLCDFGISQFVYTHNKNDQDLYYTLIGT

NQYIAPEVIEKKGHTNLIDIYSLGKTLLSLSKRNTGFVYNRIYLKLFEIMT-NPFETRPNVNQLIEFMCRHHENLKYTLLVSDFQHRDSIKCLNYLKEKL
|||.|||.....|.|..||||....|....|.|...|.||.|...|...|. |||..||.|.|.|||||....|..||..||||.|..|..|.||.|.|.
NQYQAPEIYQEEGYTCNIDIYNQHYTMDVFSNRVHQFQYNCIMKHLMKMMNCNPFKLRPFVDQMIEFMCCQYDNIRYTIFVSDFTHPNSRDCINYFKNKK

IGILDN---------KTNPLKKIHIDMEFQGKTYHCNGVLRSEYLRN------EYILE
..||.|         |..|...|||||..|.|.|||.|...||||.|      .|...
FNILKNFQLCTLENFKIRPSIDIHIDMKCQQKDYHCYGIIQSEYLHNNTRSIIFYYID
Kinase DDB0231281.AA Ciliate-E2 40-226 18 2.1e-19 63.25 In-house 14-283 (365) Show / Hide 
Range on Protein: 40-226
Range on HMM: 14-283/365
Sequence Identity: 18% (53 aa)

CVLKEIKYLNNKKKL--------------EEFKKEEKNEEGIQKR--IYQRNFNLEF----------NHLKNFSQMNHTSIIKYIEHIESKDEFGLVDRC
.| |  .....|..               |..|. ... . ..|.  ... . . ..          | ... .|.||  |||..|. ..||.    . .
SVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDD----NNI

IFVTEYYEDGDLSS------IKE---------IEFKDIINLFLKML---------------INLKEFQN-V-IIHRDIKPENIFLRKFKNNDGKVELDCY
 .|.||.. ||| .      .|.         .  | |.... . |                 |..  .   |||||||||||..             . 
YLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-------------IK

LGDYGSAQTLYTQNKSTL---------------------------------IGTNQYIAPEVIEKKG---------HTNLIDIYSLG
. | | .. . ..|. ..                                 .||  | |||....|.         ..  .||.|||
IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG
Kinase DDB0231281.AA Ciliate-E2b 134-229 34 3e-17 49.14 In-house 105-200 (272) Show / Hide 
Range on Protein: 134-229
Range on HMM: 105-200/272
Sequence Identity: 34% (37 aa)

KDIINLFLKMLINLKEFQNVIIHRDIKPENIFLRKFKNNDGKVELDCYLGDYGSAQTLYTQNK-----STLIGTNQYIAPEVIE-----KKGHTNLIDIY
...|   .. |  |   .. ||.|||||||| .     ..|     ..| | | | ..|..|       |.|||  | |||.|.      || |   ||.
QFYIASICLCLEYLH--NQNIIYRDIKPENIMV----DHKGY----MKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIW

SLGKTL
|.| .|
SVGICL
Kinase DDB0231281.AA STE 32-226 18 6.9e-16 52.68 In-house 18-255 (359) Show / Hide 
Range on Protein: 32-226
Range on HMM: 18-255/359
Sequence Identity: 18% (51 aa)

AKDK----------------SGKLCVLKEIKYLNNK----------------KKLEEFKKEEKNEEGIQKRIYQRNFNLEFNHLKNFSQMNHTSIIKYIE
|...                .|...  |.... |..                .......|| |     ..                   | |  |.||. 
AMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNH-------------------M-HPNIVKYYG

HIESKDE-FGLVDRCIFVTEYYEDGDLSSIKE------IEFK-----------DIINLFLKM----LINLKEFQNVIIHRDIKPENIFLRKFKNNDGKVE
. . ...  .  | .  . || . | |..| .       ...           ..|  ...     | .... .. |||||||| ||.|           
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL-----------

LDCYLGDYGSAQTLYT------------------QNKSTLIGTNQYIAPEVIEK------KGHTNLIDIYSLG
  . | | | .  |                    |.  |..||  . |||||..      ||..   ||.|||
--VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLG
Kinase DDB0231281.AA AGC 154-226 20 1.4e-15 35.25 In-house 175-292 (395) Show / Hide 
Range on Protein: 154-226
Range on HMM: 175-292/395
Sequence Identity: 20% (26 aa)

IIHRD-IKPENIFLRKFKNNDGKVELDCYLGDYGSA-------------------------------------QTLYTQNK---------------STLI
||||| .||||| | .           . | | |..                                     ..   .|.               .|. 
IIHRDYLKPENILLDED--------GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFC

G--TNQYIAPEVIEKKGHTNLIDIYS--LG
|  | .|.|||..    ..   |..|  ||
GPCTPEYMAPEIL----YGKACDWWSFGLG
Kinase DDB0231281.AA Pkinase 154-226 32 2.2e-13 48.42 Pfam 129-199 (293) Show / Hide 
Range on Protein: 154-226
Range on HMM: 129-199/293
Sequence Identity: 32% (25 aa)

IIHRDIKPENIFLR-KFKNNDGKVELDCYLGDYGSAQ---TLYTQNKSTLIGTNQYIAPEVIE-KKGHTNLIDIYSLG
|||||.|||||..  .  ...     .  ..| |.|    .   .  .|. ||  |.|||||   ....  .|..|.|
IIHRDLKPENILIDNNGHIDA-----CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG
Kinase DDB0231281.AA S_TKc 22-313 17 3.9e-13 15.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-313
Range on HMM: 1-231/231
Sequence Identity: 17% (57 aa)

NNLEERL-------ISIAKDKS-GKLCVLKEIKYLNNKKKLEEFKKEEKNEEGIQKRIYQRNFNLEFNHLKNFSQMNHTSIIKYIEHIESKDEFGLVDRC
  . . .          ...|. |... .|.||                           ...  | . ||.    .|  |.|.......       |. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------EHIRREIQILKK----HHPNIVKLYDVFQD-------DHL

IFVTEYYED--GDLSS-IKE---------IEFKDIINLFLKMLINLKEFQNV-IIHRDIKPENIFLRKFKNNDGKVELDCYLGDYGSAQTLYTQNKSTLI
 .|.|| .   ||| . ||.         .   ..  ..  ..  |.   .  |||||.|||||.| .             ..| |.|  |     .|..
YMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------HIKICDFGLARQL-----TTFC

GTNQYIAPEVIEKKGHTN-LIDIYSLGKTLLSLSKRNTGFVYNRIYLKLFEIMTNPFETRPNVNQLIEFMCRHHENLKYTLLVSDFQHRDSI----KCLN
||  |.||||.   |..   .|..|.| .|  .  . . |     . ..|...                                   .. .    |||.
GTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG---------------------------------SPEAKDFIRKCLQ

YLKEKLIGILDNKT-------NPLK
.  || ... .  .        |  
KDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0231281.AA TKL 154-226 19 6.5e-13 42.84 In-house 161-276 (364) Show / Hide 
Range on Protein: 154-226
Range on HMM: 161-276/364
Sequence Identity: 19% (23 aa)

IIHRDIKPENIFLRKFKNN------DGKVELDCYLGDYGSAQTLYTQN---------------------KSTLIGTNQYIAPEVIEKK------------
|||||.|..||.. .  .|      . . . .| ..|.| .... . .                     ..| .|| .. ||||....            
IIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEF

----GHTNLIDIYSLG
      .  .|.|| |
CKGFEYSEKCDVYSFG
Kinase DDB0231281.AA Ciliate-B1 154-226 31 1.3e-12 40.61 In-house 139-216 (290) Show / Hide 
Range on Protein: 154-226
Range on HMM: 139-216/290
Sequence Identity: 31% (27 aa)

IIHRDIKPENIFLRKF-------KNNDGKVELDCYL---GDYG--SAQTLYTQNKSTLIGTNQYIAPEVIE-KKGHTNLIDIYSLG
|.|||.|||||...|        | ...      |.   .|.|  ..|  | ...|. .||  |.|||... ..  .. .|| |.|
ICHRDLKPENILIHKKNVPIYYNKQQNH------YIFKITDFGISKMQQEY-MMQSC-VGTINYMAPEILNFNQQYDKKVDIWSFG
Kinase DDB0231281.AA RSK 154-226 35 1.4e-11 38.97 In-house 125-199 (278) Show / Hide 
Range on Protein: 154-226
Range on HMM: 125-199/278
Sequence Identity: 35% (28 aa)

IIHRDIKPENIFLRKFKNNDGKVELDCYLGDYGSAQTL---YTQNKSTLIGTNQYIAPEVIE----KKGHTNLIDIYSLG
|||||.||||| .   . |.| .     | | | .  .   ..|   | ..| .|.|||..     ..||.   |..|||
IIHRDLKPENILYDDES-NEGHI----KLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG
Kinase DDB0231281.AA Ciliate-E2-Unclassified 29-226 19 5.3e-10 30.92 In-house 15-257 (352) Show / Hide 
Range on Protein: 29-226
Range on HMM: 15-257/352
Sequence Identity: 19% (52 aa)

ISIAKDKSGK-------LCVLKEIKYLNNKKKLEEFKKEEKNEEGIQ-------KRIYQRNFNLEFNHLKNFSQMNHTSIIKYIEHIESKDEFGLVDRCI
.  ...|. |       ... ...| .. ..|  |.. |.| .. ..       ..| |            .....|  |.|.... ..|.       ..
VYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQ----------ILLNHPHPFIVKMFYCFQDKQN------IY

FVTEYYEDGDLSS-IKE--------------------IEFKDII-----NLFLKMLINL-KEFQNV-IIHRDIKPENIFLRKFKNNDGKVELDCYLGDYG
.|.|| |.|||.  ||.                    .. . ..     ..|   |  | .  ..  |||||||||||.. . ..      . . . |.|
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-----NYYIKIIDFG

SAQ-----------------TLYTQNKSTLIGTNQYI----APEVIEKKGHTNL----IDIYSLG
..                   .. |. .| .||..|.    ||||...... .     .||.|||
ISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG
Kinase DDB0231281.AA CAMK 154-226 20 2.2e-09 25.64 In-house 280-401 (425) Show / Hide 
Range on Protein: 154-226
Range on HMM: 280-401/425
Sequence Identity: 20% (25 aa)

IIHRDIKPENIFLRKFKNNDG---------KVELDCYLGDYGSAQTL-------------------------YTQNKSTLIGTNQYIA-PEVIEK-----
|.|||.||||| | . ....              .  . | | |. .                         ..|  .|  ||  |.| |||...     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KGHTNLIDIYSLG
         ....  .|. |.|
MQNATDEEKPYYGPKCDMWSCG
Kinase DDB0231281.AA Ciliate-B1 116-125 60 0.124822 1.62 In-house 95-104 (290) Show / Hide 
Range on Protein: 116-125
Range on HMM: 95-104/290
Sequence Identity: 60% (6 aa)

VTEYYEDGDL
..||.|.|||
IMEYCEQGDL
Kinase DDB0231281.AA Dicty9 1352-1571 40 2.2e-101 343.15 In-house 26-262 (356) Show / Hide 
Range on Protein: 1352-1571
Range on HMM: 26-262/356
Sequence Identity: 40% (97 aa)

VFRNISFFENKKLFEKFDTNVNFQKEIEFVKNYSKFLNFDISNRIP-REYSILKSIKGMNGVVQIDSWYLENDIIYILMDYFDGQ-NLLEVSQDLINDFT
|   | .  |..  . || ..  ..|  . | ||.  | .  | |. ....|.|.||......|||.|||||..|||...|..|. |||....|..|...
VCKEIDYNNNNNKKDEFD-KEKRNREYIQLKQYSRNFNLEF-NHIKFSHMNITKYIKHFEHIEQIDEWYLENKCIYIMEYYHGGDCNLLKINNDKCNEMD

LFSILNQLSKILFELETVYS-IHHRDLKPDNILIKN-------DLTICLADFGISHFS-KELKNDQDLYYSKDGTLGYQSPEIYSSELRG-NGDIKNQPY
||.|..|..|.|..|..... |.|||.||.||..|.       ||..||.|||||.|. ...||||||||...||..||.||||..|... |.||.||.|
LFDIIYQFCKMLHILKEFQNVIIHRDIKPENIFFKRYNNDGNIDLDCCLCDFGISQFVYTHNKNDQDLYYTLIGTNQYQAPEIYQEEGYTCNIDIYNQHY

KMDVFG-------LRCVMKYLMSKFNSSSSKLKELVEKM
.||||.       ..|.||.||...|....||...|..|
TMDVFSNRVHQFQYNCIMKHLMKMMNCNPFKLRPFVDQM
Kinase DDB0231281.AA Ciliate-E2-Unclassified 1425-1546 23 7.9e-20 65.47 In-house 96-256 (352) Show / Hide 
Range on Protein: 1425-1546
Range on HMM: 96-256/352
Sequence Identity: 23% (38 aa)

IYILMDYFDGQNLLEVSQDLIN----------------DFTLFSIL-----NQLSKILFEL-ETVYS--IHHRDLKPDNILIKNDL---TICLADFGISH
||| |.|..|..|..  ..  .                 || . ..     . .  ||  |    ..  | |||.||.|||..|.     |...||||| 
IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISK

FSKEL------------KNDQDLYYSKDGTLGYQ----SPEIYSSELRGNGDIKNQPYKMDVFGL
....              ..|...... ||..|.    .||.. ..  ..       || |...|
KYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----YKCDIWSL
Kinase DDB0231281.AA Ciliate-E2 1425-1546 20 3.9e-17 55.35 In-house 109-282 (365) Show / Hide 
Range on Protein: 1425-1546
Range on HMM: 109-282/365
Sequence Identity: 20% (37 aa)

IYILMDYFDGQNLLEVSQDL-------------INDFTLFSILNQLSK---------------ILFELETVYSIHHRDLKPDNILIKNDLTICLADFGIS
||. |.|..|..|..  ..              ....    |  |. .                | .|    .| |||.||.|||.     |...|||.|
IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLS

HF-------------SKELKNDQ----------------DLYYSKDGTLGYQSPEIYSSELRGNGDIKN-QPYKMDVFGL
 .             .|.... .                .....  ||.||..|||....  .|   ..   || |.. |
KKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL
Kinase DDB0231281.AA TKL 1472-1523 24 1.6e-14 48.68 In-house 163-244 (364) Show / Hide 
Range on Protein: 1472-1523
Range on HMM: 163-244/364
Sequence Identity: 24% (20 aa)

HRDLKPDNILIKNDLT--------------ICLADFGISHFSKELKNDQDL----------------YYSKDGTLGYQSPEI
|||||..|||.....|              ....|||.| | .. .|..|                  ... ||... .||.
HRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEV
Kinase DDB0231281.AA AGC 1472-1523 24 1.8e-14 32.38 In-house 177-278 (395) Show / Hide 
Range on Protein: 1472-1523
Range on HMM: 177-278/395
Sequence Identity: 24% (26 aa)

HRD-LKPDNILIKNDLTICLADFGISHFSKELKNDQ--------------------------------------------------DLYYSKDG--TLGY
||| |||.|||. .|  |.|.|||   ..||..||.                                                  |. ..  |  |  |
HRDYLKPENILLDEDGHIKLTDFG---LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEY

QSPEI
 .|||
MAPEI
Kinase DDB0231281.AA CAMK 1472-1539 20 6.2e-14 40.59 In-house 202-310 (425) Show / Hide 
Range on Protein: 1472-1539
Range on HMM: 202-310/425
Sequence Identity: 20% (23 aa)

HRDLKPDNILIKND-----------------LTICLADFGISHFSKELKNDQ--------------------DLYYSKDGTLGYQS-PEIYSSELRGNGD
||||||.|||. ..                  .| ..||| . . .. .|.                     ....   ||..| . ||. ... ..|  
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ

IKN-----QPY
  |     .||
--NATDEEKPY
Kinase DDB0231281.AA Pkinase 1472-1539 32 1.6e-12 45.33 Pfam 131-189 (293) Show / Hide 
Range on Protein: 1472-1539
Range on HMM: 131-189/293
Sequence Identity: 32% (24 aa)

HRDLKPDNILIKNDLTI----CLADFGIS-HFSKELKNDQDLYYSKDGTLGYQSPEIYSSELRGNGDIK-NQPY
||||||.||||.|. .|    ...|||.. .|.      .  ...  ||..| .||.          |. .|.|
HRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEV----------IRGGQYY
S_TKc DDB0231281.AA S_TKc 1299-1589 15 4.3e-12 0.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 1299-1589
Range on HMM: 1-231/231
Sequence Identity: 15% (51 aa)

VVDVDV--SGNSSKKKFVRKAI-GSIIDLKIIGKNYGGIDLSNPRSLGTYNLIGDSVFRNISFFENKKLFEKFDTNVNFQKEIEFVKNYSKFLNFDISNR
   ...  .|  .| . .|.   | |  .|||                                                                  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------------------------------------------EH

IPREYSILKSIKGMNGVVQIDSWYLENDIIYILMDYFDG--QNLLEVSQDL--------INDFTLFSILNQLSKILFELETVYSIHHRDLKPDNILIKND
| || .|||.  .   .|..  .. . | .|. |.| ||   .|... ..         ..  .  ... |. . |  .     | ||||||.|||. . 
IRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-

LTICLADFGISHFSKELKNDQDLYYSKDGTLGYQSPEIYSSELRGNGD----------------IKNQPYKMDVFGLRCVMKYLMSKFNSSSSKLKELVE
 .| ..|||.. .           ..  ||. | .||.      | |                     |.  ... .  ...         |. .|....
-HIKICDFGLARQL----------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG---------SPEAKDFIR

KMGFFNYDDRISLKELIE---------CL
|.  .. ..|..  |. .          .
KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0231281.AA Ciliate-E2b 1422-1523 22 1.7e-09 25.22 In-house 72-176 (272) Show / Hide 
Range on Protein: 1422-1523
Range on HMM: 72-176/272
Sequence Identity: 22% (24 aa)

NDIIYILMDYFDGQNLLEV--SQD--LINDFTLFSILNQLSKILFELETVYSIHHRDLKPDNILIKNDLTICLADFGISHFSKELKNDQDLYYSKDGTLG
.. .| .|..  |. |..|   .   |..      .  .. ..| .|    .| .||.|| ||.. ..  . |.|.|.. . .. .      ..  ||. 
DQHMYFMMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLH-NQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPH

YQSPEI
|  |||
YMAPEI
Kinase DDB0231281.AA RSK 1472-1523 37 4.1e-09 29.82 In-house 127-179 (278) Show / Hide 
Range on Protein: 1472-1523
Range on HMM: 127-179/278
Sequence Identity: 37% (21 aa)

HRDLKPDNILIKN---DLTICLADFGISHFSKELKND-QDLYYSKDGTLGYQSPEI
||||||.|||  .   . .| | |||   |.|....|   . ..  .|. |  ||.
HRDLKPENILYDDESNEGHIKLTDFG---FCKQFRCDHNQWTMTFCYTIEYMAPEM
Kinase DDB0231281.AA Ciliate-B1 1470-1501 40 2.6e-07 21.78 In-house 139-182 (290) Show / Hide 
Range on Protein: 1470-1501
Range on HMM: 139-182/290
Sequence Identity: 40% (18 aa)

IHHRDLKPDNILIK------------NDLTICLADFGISHFSKE
| ||||||.||||             | . .  .||||| ...|
ICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQE
Kinase DDB0231281.AA STE 1472-1496 48 5.1e-07 20.97 In-house 175-194 (359) Show / Hide 
Range on Protein: 1472-1496
Range on HMM: 175-194/359
Sequence Identity: 48% (12 aa)

HRDLKPDNILIKNDLTICLADFGIS
|||.||.|||.     . |.|||..
HRDIKPANILL-----VKLCDFGVC
Kinase DDB0231281.AA TyrKc 1372-1589 13 2.1e-05 -135.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 1372-1589
Range on HMM: 1-280/280
Sequence Identity: 13% (41 aa)

VNFQKEI---EF----------------VKNYSKFLNFDISNRIPREYSILKSI--KGMNGVVQIDSWYLEN-------DIIYILMDYFDG---QNLLEV
. . |..   .|                .|...          . || .|....  .  | .|..    ..        . ..|.| | ..   .. |  
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-------REDFMREARIMCKLGGHHPN-IVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

SQDLINDFTLFSILNQLSKILFELETVYSIHHRDLKPDNILIKNDLTICLADFGISHFSKELKND------QDLYY-----SKD--GTLGYQSPEIYSSE
... ..  .| |.  | ..    |.    . ||||   |.|.....|.  .|||    |.....|      .| |      ...    .   .||     
HRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGL---SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---

LRG--------------------NGDIKNQP-----YKMDVFGLRCVMKYLMSKFNS--------SSSKLKELVEKMGFFNYDDRISLKELIECL
  |                    .|.           . .    .    | | .  .         .... .. ..   .. .|| . .|..||.
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0231281.AA Pkinase 1398-1434 33 2.073966 2.53 Pfam 47-84 (293) Show / Hide 
Range on Protein: 1398-1434
Range on HMM: 47-84/293
Sequence Identity: 33% (13 aa)

R--EYSILKSIKGMNGVVQIDSWYLENDIIYILMDYFDG
|  | .|.|...  | .|..  |. ..| ||. |.| .|
RLSEIQIMKRLNHPN-IVRLYDWFEDKDHIYMVMEYCEG