Gene DDB0230037 (Slime mold)

DDB0230037

Species: Slime mold
Alias: DDB0230037, DdisK087
External Links: DictyBase Link ,
Annotation: Secondary Group: Other, Secondary Family: Dicty9

Classification

Group: Other
Family: Dicty9

Sequence

Name Sequence Type Origin Length Description Download
DDB0230037.AA Protein None 1433 None Fasta, JSON
DDB0230037.kin_dom Protein Kinase Domain None 309 None Fasta, JSON
DDB0230037.kin_dom2 Protein Kinase Domain None 156 None Fasta, JSON

Protein domain

Protein domains of DDB0230037.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0230037.AA Dicty9 14-322 48 5e-203 680.77 In-house 1-356 (356) Show / Hide 
Range on Protein: 14-322
Range on HMM: 1-356/356
Sequence Identity: 48% (172 aa)

LLKSFADKDEERNVYIVLNKSNEKFICKEIIYTQNSN----IDNEKRKSEYINLKKFS-------DTIKYPHLNISKYIEHFIILENQQEKEKIKKQYII
.|....|..||||||||.|||.....||||.|..|.|    .|.|||..|||.||..|       ..||..|.||.|||.||...|...|.....|...|
ILHEINDNNEERNVYIVKNKSGKLCVCKEIDYNNNNNKKDEFDKEKRNREYIQLKQYSRNFNLEFNHIKFSHMNITKYIKHFEHIEQIDEWYLENKCIYI

TEFYDGGDLSSLKITNKKCFSIKNGDIIYLFLKMLIIFKEFQTVIIHRDIKP----------DGSIVNDYYLCDLGSSTQVKTINSS------TLIGTNQ
.|.|.|||...|||.|.||......||||.|.|||.|.||||.|||||||||          ||.|..|..|||.|.|..|.|.|..      |||||||
MEYYHGGDCNLLKINNDKCNEMDLFDIIYQFCKMLHILKEFQNVIIHRDIKPENIFFKRYNNDGNIDLDCCLCDFGISQFVYTHNKNDQDLYYTLIGTNQ

YIAPDVIKRGGYTGTIDIYGLGKTLLLLLNRVQQNQYNKINKILFEMMCSNESTERPTVDQLIEFMVCQYDNISFTEFD-DFTHPLSKDCIEYFKNNKLN
|.||......|||..||||....|.....|||.|.|||.|.|.|..||..|....||.|||.||||.||||||..|.|. |||||.|.|||.||||.|.|
YQAPEIYQEEGYTCNIDIYNQHYTMDVFSNRVHQFQYNCIMKHLMKMMNCNPFKLRPFVDQMIEFMCCQYDNIRYTIFVSDFTHPNSRDCINYFKNKKFN

ILKK---------DVKP---IQIKIKIKEKEYRAYGAIQ-ALLRN------FYYID
|||.         ...|   |.|..|...|.|..||.|| ..|.|      |||||
ILKNFQLCTLENFKIRPSIDIHIDMKCQQKDYHCYGIIQSEYLHNNTRSIIFYYID
Kinase DDB0230037.AA Ciliate-E2b 147-211 34 1.5e-11 31.5 In-house 123-200 (272) Show / Hide 
Range on Protein: 147-211
Range on HMM: 123-200/272
Sequence Identity: 34% (27 aa)

IIHRDIKPDGSIVND---YYLCDLGSSTQVKTINS-----STLIGTNQYIAPDVIK-----RGGYTGTIDIYGLGKTL
||.|||||   .|      .| |.| .   .. |.      |.|||  | ||..|.       |||   ||. .| .|
IIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL
Kinase DDB0230037.AA AGC 164-208 12 4.9e-11 23.26 In-house 370-466 (395) Show / Hide 
Range on Protein: 164-208
Range on HMM: 370-466/395
Sequence Identity: 12% (13 aa)

LCDLGSSTQVKTIN----------------------------------------------------SSTLIG--TNQYIAPDVIKRGGYTGTIDIYG--L
|.| |....... .                                                     .|. |  | .|.|| ..    |. . |...  |
LTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGL

G
|
G
S_TKc DDB0230037.AA S_TKc 9-252 20 5.1e-11 -15.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-252
Range on HMM: 1-231/231
Sequence Identity: 20% (57 aa)

YKIHSLLK--SFADKDEERNVYIVLNKS-NEKFICKEIIYTQNSNIDNEKRKSEYINLKKFSDTIKYPHLNISKYIEHFIILENQQEKEKIKKQYIITEF
|.|. ..   .|.       || . .|. .... .|.|          |. ..|   |||        | || |....|            .. |...|.
YEILRKIGKGAFG------KVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-------HHPNIVKLYDVFQD----------DHLYMVMEY

YDG--GDLSSLKITNKK---CFSIKNGDIIYLFLKMLIIFKEFQTV-IIHRDIKPD----GSIVNDYYLCDLGSSTQVKTINSSTLIGTNQYIAPDVIKR
 ||  ||| ..   ...   .| .   .. ...  ..   .      |||||.||.     .      .|| |...|.     .|..||  |.|| |.  
CDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL--

GGYTG-TIDIYGLGKTLLLLLN-RV----QQNQYNKIN----KILFEMMCSNESTERPTVDQLIE---------FM
 ||..  .|.. .| .|  .|  .     .|  ..||     | . . ..  . ..|||. .. .         ..
-GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0230037.AA Ciliate-E2-Unclassified 147-208 25 7e-10 30.48 In-house 179-271 (352) Show / Hide 
Range on Protein: 147-208
Range on HMM: 179-271/352
Sequence Identity: 25% (24 aa)

IIHRDIKPD----GSIVN--DYYLCDLGSST-----------------QVKTINSSTLIGTNQYI----APDVIKRGGYTGT----IDIYGLG
||||||||.     .  .     ..|.|.|                  . |  ...| .||..|.    || |... .| ..    .||..||
IIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG
Kinase DDB0230037.AA STE 147-208 30 8e-10 30.99 In-house 173-255 (359) Show / Hide 
Range on Protein: 147-208
Range on HMM: 173-255/359
Sequence Identity: 30% (26 aa)

IIHRDIKPDGSIVNDYYLCDLGSSTQVKTI------------------NSSTLIGTNQYIAPDVIKR------GGYTGTIDIYGLG
||||||||.   .    ||| | ..|.  .                  .. |..||  . || ||..      .||.   ||. ||
IIHRDIKPANILL--VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLG
Kinase DDB0230037.AA ASK 147-212 40 5.6e-09 25.79 In-house 115-188 (254) Show / Hide 
Range on Protein: 147-212
Range on HMM: 115-188/254
Sequence Identity: 40% (30 aa)

IIHRDIKPDGSIVNDY----YLCDLGSSTQVKTIN--SSTLIGTNQYIAPDVIKRG--GYTGTIDIYGLGKTLL
|.||||| |  .|| |     . | | .  .  ||  ..|  || ||.||.|| .|  ||    ||. .| |..
IVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTETFTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTMV
Kinase DDB0230037.AA C8 144-211 30 2.7e-08 25.04 In-house 141-226 (226) Show / Hide 
Range on Protein: 144-211
Range on HMM: 141-226/226
Sequence Identity: 30% (26 aa)

QTVIIHRDIKPDGSI---VNDYY----LCDLGSSTQVKTINS---STL---IGTNQYIAPDVIKR-----GGYTGTIDIYGLGKTL
.. |.||||||.       . |     |||.| ..||.   |   |     .|| .|.|| ..|        |.   |.. .|  |
CKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase DDB0230037.AA Ciliate-E2 27-208 17 3.3e-07 20.78 In-house 15-283 (365) Show / Hide 
Range on Protein: 27-208
Range on HMM: 15-283/365
Sequence Identity: 17% (48 aa)

VYIVLNKSNEKFICKEIIYTQNSNIDN---EKRKSEYINLKKFSD---TIKYPHLNISKYIE----------------HFIILENQQEKE--KIKKQYII
|| . .... | . . ||. |.. ...   || |. ....| ..     ..   ..| . |.                |  |..     .  . .. |..
VYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLV

TEFYDGGDLSS-LKITNKKCFSI-------KNGDIIYLFLKML---------------IIFKEFQT-V-IIHRDIKPDGSIVNDYYLCDLGSSTQVKTIN
.|...|||| . .|. .||....       .   |.|.. . |                 ...      ||||||||.  ..    ..|.| |..... |
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--IKIIDFGLSKKYDDDN

SSTL---------------------------------IGTNQYIAPDVIKRGG---------YTGTIDIYGLG
  ..                                 .||  | || ......         |.  .||. ||
QNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG
Kinase DDB0230037.AA Ciliate-C8 147-211 26 3e-06 18.91 In-house 140-238 (238) Show / Hide 
Range on Protein: 147-211
Range on HMM: 140-238/238
Sequence Identity: 26% (26 aa)

IIHRDIKPDGSIVNDY-------YLCD------LGSSTQVKTINS----STLIGTNQY-----------IAPDVIKR------GGYTGTIDIYGLGKTL
|.||||||.   |..         |||      .| ..|..   |    ..  || ||           .|| |.|         ..   |.| .|  |
IMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase DDB0230037.AA Pkinase 147-208 28 2.4e-05 20.01 Pfam 143-213 (293) Show / Hide 
Range on Protein: 147-208
Range on HMM: 143-213/293
Sequence Identity: 28% (21 aa)

IIHRDIKPDGSIVN-DYYL------CDLGSST---QVKTINSSTLIGTNQYIAPDVIK-RGGYTGTIDIYGLG
|||||.||.   .. ....      || |..      .    .|. ||  |.|| ||. . .|.  .|....|
IIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG
Kinase DDB0230037.AA Dicty9 1266-1422 44 3.7e-92 312.49 In-house 87-262 (356) Show / Hide 
Range on Protein: 1266-1422
Range on HMM: 87-262/356
Sequence Identity: 44% (78 aa)

NIERYYLENDKIYAMFPYVNGSCNLSEIDN--LNEMDLLNILYQLCFQLHQLENLG--IFHRDVKPENIISLRYGNG---GIVVFIVDFGISQYKGKHLE
.|...||||..||.|..|..|.|||..|.|  .|||||..|.||.|..||.|....  |.|||.|||||...||.|.   .......||||||....|..
QIDEWYLENKCIYIMEYYHGGDCNLLKINNDKCNEMDLFDIIYQFCKMLHILKEFQNVIIHRDIKPENIFFKRYNNDGNIDLDCCLCDFGISQFVYTHNK

N----YYSRDGTFGYQAPEIYREELRG-DGDIKTQKYKMDVFS-------LGCTMAFLIKKFNITSTYLNDFIDNM
|    ||...||..|||||||.||... ..||..|.|.|||||       ..|.|..|.|..|.....|..|.|.|
NDQDLYYTLIGTNQYQAPEIYQEEGYTCNIDIYNQHYTMDVFSNRVHQFQYNCIMKHLMKMMNCNPFKLRPFVDQM
Kinase DDB0230037.AA Ciliate-E1 1295-1395 29 9.3e-17 51.41 In-house 105-202 (202) Show / Hide 
Range on Protein: 1295-1395
Range on HMM: 105-202/202
Sequence Identity: 29% (30 aa)

NLNEMDLLNILYQLCFQLHQLENLGIFHRDVKPENIISLRYGNGGIVVFIVDFGISQ-YKGKHLENYYSRDGTFGYQAPEIYR-EELRGDGDIKTQKYKM
....  ...| .|| ..| .|....| ||| ||.||.  ..||. .     |||||. .| . ....  .  |  |. || |  .|.    . .. .|| 
QFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC----DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKS

DVF
|..
DIY
Kinase DDB0230037.AA Ciliate-E2-Unclassified 1296-1401 24 7e-14 44.55 In-house 135-260 (352) Show / Hide 
Range on Protein: 1296-1401
Range on HMM: 135-260/352
Sequence Identity: 24% (32 aa)

LNEMDLL-----NILYQLCFQL-HQLENLGIFHRDVKPENIISLRYGNGGI--VVFIVDFGISQYKGKH---------------LENYYSRDGTFGYQ--
. |   .     ....|..  | .  ....| ||| |||||.   . |.|    . | ||||| . ..                 ...... || .|.  
FTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL---FDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQ

--APEIYREELRGDGDIKTQKYKMDVFSLGCTM
  |||.....  ..       || |..|||. .
YTAPEVLQGQNYDHSKA----YKCDIWSLGVIL
Kinase DDB0230037.AA Ciliate-E2 1290-1401 22 2.7e-13 41.96 In-house 133-286 (365) Show / Hide 
Range on Protein: 1290-1401
Range on HMM: 133-286/365
Sequence Identity: 22% (38 aa)

LSEID---NLNEMDLLNILYQLCF---------------QLHQLENLG-IFHRDVKPENIISLRYGNGGIVVFIVDFGISQYKGKHLEN-----------
..||.   ...|   ..| .|..                 |. | . . |.||| |||||.          ..|.|||.|..  .  .|           
NHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYM

--------------------YYSRDGTFGYQAPEIYR-EELRGDGDIKTQK---YKMDVFSLGCTM
                    ...  || ||.||||.. ..  ..   ..||   || |..|||...
FKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---QKQKGYDYKCDIWSLGVIL
Kinase DDB0230037.AA C8 1320-1401 31 5.4e-13 41.53 In-house 144-226 (226) Show / Hide 
Range on Protein: 1320-1401
Range on HMM: 144-226/226
Sequence Identity: 31% (27 aa)

IFHRDVKPENIISLRYGNGGIVVFIVDFGISQYKGKHLENYYSRD----GTFGYQAPEIYREELRGDGDIKTQKYKMDVFSLGCTM
| |||.||.|.     .| |  . . |||.. . .|  . ..|..    ||..| ||||  ..   | . |  . . |.||.|  .
IMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQ---DNQYKQYRIQSDLFSVGLVL
Kinase DDB0230037.AA STE 1315-1401 25 7e-09 27.62 In-house 168-258 (359) Show / Hide 
Range on Protein: 1315-1401
Range on HMM: 168-258/359
Sequence Identity: 25% (27 aa)

LENLGIFHRDVKPENIISLRYGNGGIVVFIVDFGISQYKGKH----------------LENYYSRDGTFGYQAPEIYREELRGDGDIKTQKY--KMDVFS
|....| |||.|| ||           | ..|||..    ..                 .. ..  ||  . |||. . . .|      ..|  | |. |
LHSHHIIHRDIKPANILL---------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R---DKGYDTKCDIWS

LGCTM
||||.
LGCTI
Kinase DDB0230037.AA Pkinase 1312-1402 31 2.3e-08 30.69 Pfam 124-203 (293) Show / Hide 
Range on Protein: 1312-1402
Range on HMM: 124-203/293
Sequence Identity: 31% (30 aa)

LHQLENLGIFHRDVKPENIISLRYGNGGIV---VFIVDFGISQYK-GKHLENYYSRDGTFGYQAPEIYREELRGDGDIKTQKYKMDVFSLGCTMA
.|.    || |||.|||||    . | | .   | | |||..  .   . . .... || .| |||. |       . .   .| |..|.||...
CHSM---GIIHRDLKPENIL---IDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------GGQYYGPKVDMWSCGCILY
Kinase DDB0230037.AA Ciliate-C8 1320-1401 25 2.3e-08 26.44 In-house 140-238 (238) Show / Hide 
Range on Protein: 1320-1401
Range on HMM: 140-238/238
Sequence Identity: 25% (26 aa)

IFHRDVKPENIISLRYGNGGIVVFIVD------FGISQYKGKHLENYYSRD-------------GTFGYQAPEIYREELRGDGDIKTQKYKMDVFSLGCT
| ||| ||.|.      ...  . . |      || . .  |  . |.|.              |..|| |||.. .  |   || . |   |..|.|  
IMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKK--SDSYSVGLV

M
.
L
Kinase DDB0230037.AA Ciliate-E2b 1274-1374 27 1.1e-07 19.57 In-house 72-176 (272) Show / Hide 
Range on Protein: 1274-1374
Range on HMM: 72-176/272
Sequence Identity: 27% (30 aa)

NDKIYAMFPYVNGSCNLSEIDNLN-----EMDLLNILYQLCFQLHQLENLGIFHRDVKPENIISLRYGNGGIVVFIVDFGISQYKGKHLE---NYYSRDG
....| |  ..||   .. | ...     . | . .  ..|  |  | |..| .||.|||||.    |     . ..|.|.. .  |  |     ..  |
DQHMYFMMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKG----YMKLIDMGTAKHMYKKNEQMTRTFTIIG

TFGYQAPEI
|  | ||||
TPHYMAPEI
Kinase DDB0230037.AA ASK 1312-1401 33 4e-06 16.09 In-house 107-187 (254) Show / Hide 
Range on Protein: 1312-1401
Range on HMM: 107-187/254
Sequence Identity: 33% (30 aa)

LHQLENLGIFHRDVKPENIISLRYGNGGIVVFIVDFGISQYKGKHLENYYSRDGTFGYQAPEIYREELRGDGDIKTQKYKMDVFSLGCTM
|. | .  | |||.| .|..   |     || | ||| ..   .      .  ||  | |||.  .  || |         |..|.||||
LKYLHENQIVHRDIKGDNVLVNTYSG---VVKISDFGTCKRLAGINPCTETFTGTLQYMAPEVIDQGQRGYGKP------ADIWSFGCTM
Kinase DDB0230037.AA AGC 1317-1330 62 2.5e-05 8.15 In-house 171-186 (395) Show / Hide 
Range on Protein: 1317-1330
Range on HMM: 171-186/395
Sequence Identity: 62% (10 aa)

N-LGIFHRD-VKPENI
. .|| ||| .|||||
SHMGIIHRDYLKPENI