Gene DDB0230007 (Slime mold)

DDB0230007

Species: Slime mold
Alias: DdisK110, DDB0230007
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
DDB0230007.AA Protein None 854 None Fasta, JSON
DDB0230007.kin_dom Protein Kinase Domain None 236 None Fasta, JSON

Protein domain

Protein domains of DDB0230007.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0230007.AA Ciliate-E2-Unclassified 70-266 27 2.2e-36 123.69 In-house 152-352 (352) Show / Hide 
Range on Protein: 70-266
Range on HMM: 152-352/352
Sequence Identity: 27% (64 aa)

IMNALYYLHSNN-IIYADLKPSNILIDSKG---IFKLNSINNSILIENNNNNNNNNNNNNNNNNNNNNNNQQIMITSRQQIFNLYNNNIDNDNNNNINES
| ..| |||..| ||. |.||.|||.|..|     |.    .|. ...|||.  .|.                      |      ....... . .  .
ILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQ----------------------Q---QKMQIWKQQMMWTFCGT

IYYL----SPEVLKGYTYS----FSSDIWSFGVLLFKCITGYYPFYSNDATK----------------LIESIIYDNYLDPI-------IRLPSDNNDLI
..|.    .||||.|  |.    ...||||.||.|. ...||||||.|. ..                |.. |.  |.  |         ...    |.|
PNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFI

QQQHFNDLISKILEKNPQKRITWPKLFIHPFF
.     ||..|.|.||| ||||..... ||.|
N-----DLLQKMLKKNPNKRITFEQILNHPWF
Kinase DDB0230007.AA AGC 70-266 21 7.9e-36 88.85 In-house 162-395 (395) Show / Hide 
Range on Protein: 70-266
Range on HMM: 162-395/395
Sequence Identity: 21% (57 aa)

IMNALYYLHS-NNIIYAD-LKPSNILIDS-------------KGIF------------KLNSINNSILIENNNNNNNNNNNNNNNNNNNNNNNQQIMITS
|  || |||| ..||. | ||| |||.|.             .|.             |...  |.   .  . |.. . |                   
IVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS-NMD-T-N-------------------

RQQIFNLYNNNIDN------------DNNNNINE--SIYYLSPEVLKGYTYSFSSDIWS--FGVLLFKCITGYYPFYSN----------DATKLIESIIY
  .  |..| . .|            | .. .    .  |..||.|    |... |.||  .|.|..  .||| |||..          .  .. ..|..
--K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMN

DNYLDP-IIRLPSDNNDLIQQ-----QHFNDLISKILEKNPQKRIT----------WPKLFIHPFF
..|  .  ...|.. .  ..      .   |||.| |.|.| ||..             .  ||.|
GRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase DDB0230007.AA Ciliate-E2 54-266 19 6.7e-33 110.27 In-house 139-365 (365) Show / Hide 
Range on Protein: 54-266
Range on HMM: 139-365/365
Sequence Identity: 19% (55 aa)

SDQYLSIDTSIIFSKNIMN---------------ALYYLHSNN-IIYADLKPSNILIDSKGIFKLNSINNSILIENNNNNNNNNNNNNNNNNNNNNNNQQ
  .|...   . ..| | .               || ||||.| ||. |.||.|||.                                           
D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-------------------------------------------

IMI----TSRQQIFNLYNNNIDNDNNNNINESI--------------------------YYLSPEVLK---------GYTYSFSSDIWSFGVLLFKCITG
| |    .|...  . .|. . .  .... .                            .|..||.|.         .  |....||||.||.|. ...|
IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

YYPFYSNDATKLIESIIYDNYLDPIIRLPSDNNDLIQQQHFN---------------DLISK----ILEKNPQKRIT-WPKLFIHPFF
..||             ... ..  |..|. ....   |  .               |||.|    .|.|.|.|||| | ... ||.|
KPPF-------------QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DDB0230007.AA ULK 167-266 27 1.3e-27 93.51 In-house 216-329 (329) Show / Hide 
Range on Protein: 167-266
Range on HMM: 216-329/329
Sequence Identity: 27% (32 aa)

YYLSPEVLK----GYTYS-FSSDIWSFGVLLFKCITGYYPFYSNDATKLIESIIYDNYLDP------IIRLPSD-N---NDLIQQQHFNDLISKILEKNP
.| .|..|.    .  |. . .||||.|.... ...|..|||.. ...... ||.... .|      |   | . .   || .  . . |||.. |....
LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDE

QKRITWPKLFIHPFF
 .||.|. || ||.|
KDRISWEELFNHPWF
Kinase DDB0230007.AA ULK 155-266 20 7.5e-26 88.75 In-house 190-324 (324) Show / Hide 
Range on Protein: 155-266
Range on HMM: 190-324/324
Sequence Identity: 20% (28 aa)

DNDNNNNIN----------ESIYYLSPEVLK----GYTYS-FSSDIWSFGVLLFKCITGYYPFYSNDATKLI----ESII----YDNYLDPIIRLPSDN-
.|. . ...           . .| .|..|.    .  |. . .||||.|.... ...|.|||.|. .....    . |     .  ..     .. .. 
NNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQ-QIYIKNQPIQFPKP

-NDLIQQQHFNDLISKILEKNPQKRITWPKLFIHPFF
 .| .  . . |||.. |.... .||.|. .| ||.|
PKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase DDB0230007.AA Other-Unique 36-256 14 2e-24 80.04 In-house 1-249 (249) Show / Hide 
Range on Protein: 36-256
Range on HMM: 1-249/249
Sequence Identity: 14% (36 aa)

YYLVKRISFEYSFKEFLNSDQYLSIDTSIIFSKNIMNAL-----------------------------YYLHSNNIIYADLKPSNILIDSKGIFKLNSIN
. .. . .. ...|   |..... .. ..   . ... .                             .|.|..|.|.....| .. .... ...... |
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWMN

NSILIENNNNNNNNNNNNNNNNNNNNNNNQQIMITSRQQIFN------LYNNNIDNDNNNNINESIYYLSPEVLKGYTYSFSSDIWSFGVLLFKCITGYY
... |.|.....|||......|.||...||..... ..  .|       .......|.||| | ..|. .   . .. .. ..|.|..|.... . .|.|
CCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFGCY

PFYSNDATKLIESIIYDNYLDPIIRLPSDNNDLIQQQHFNDLISKILEKNPQKRIT
.|  |. ... ....  . ..|....... . ||.|... . .    ..... . .
HFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY
Kinase DDB0230007.AA CAMK 165-266 26 3e-22 67.84 In-house 282-425 (425) Show / Hide 
Range on Protein: 165-266
Range on HMM: 282-425/425
Sequence Identity: 26% (38 aa)

SIYYLS-PEVLKGYT--------------YSFSSDIWSFGVLLFKCITGYYPFYSN-------------DATKLIESIIYDNY--LDPIIRLPSDN----
. .| . ||||.| .              |....|.|| ||.|. . .||.|||.              .  .| | |.  .|   .| .  .| |    
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE

-NDLIQQQ-------HFNDLISKILEKNPQKRITWPKLFIHPFF
  | | ..          |||.|.|...|.||.|      ||..
WWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DDB0230007.AA Pkinase 165-266 22 5.6e-21 75.27 Pfam 174-293 (293) Show / Hide 
Range on Protein: 165-266
Range on HMM: 174-293/293
Sequence Identity: 22% (27 aa)

SIYYLSPEVLK-GYTYSFSSDIWSFGVLLFKCITGYYPFYSN--DATKLIESIIYDNYLDPIIRLPSDNNDLIQQ----------------QHFNDLISK
...|..|||.. |  |. ..|.||.|..|.  ..|. ||..   . . . .  .... ..|... .... . |                  . . |.|..
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

ILEKNPQKRITWPKLFIHPFF
.|.|.|.||.|.. .. ||.|
CLCKDPKKRPTAEQILQHPWF
S_TKc DDB0230007.AA S_TKc 3-266 16 1.8e-14 35.4 SMART 18-231 (231) Show / Hide 
Range on Protein: 3-266
Range on HMM: 18-231/231
Sequence Identity: 16% (51 aa)

IKESF-----------KRIKSDHQNQNQDQINYVDENVKENLSTYYLVKRISF-----EY---SFKEFLNSDQY------LSIDTSIIFSKNIMNALYYL
 ..             ..|..  |   .       .|.   . ...  ... .     .    . .... . ..      ..  .   . . | .|| |.
CRHKKTGRIVAIKIIKEHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYC

HSNNIIYADLKPSNILIDSKGIFKLNSINNSILIENNNNNNNNNNNNNNNNNNNNNNNQQIMIT----SRQQIFNLYNNNIDNDNNNNINESIYYLSPEV
||..||. ||||.|||.|.                                        .|.|.    .||               . .  . .|..|||
HSHGIIHRDLKPENILLDE----------------------------------------HIKICDFGLARQL--------------TTFCGTPWYMAPEV

LKGYTYSF-SSDIWSFGVLLFKCITGYYPFYSNDATKLIESIIYDNYLDPIIRLPSDNNDLIQQQHFNDLISKILEKNPQKRITWPKLFI-------HPF
|    |.. ..|.||.|..|. ...|| ||.  .  .... |                      . . |.|.|.|.|.|.||.|  ...        ||.
L---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

F
|
F
Kinase DDB0230007.AA ULK 48-102 28 3.1e-13 42.61 In-house 107-183 (329) Show / Hide 
Range on Protein: 48-102
Range on HMM: 107-183/329
Sequence Identity: 28% (22 aa)

FKEFLNSDQYLSIDT----------SIIFSKNIMNALYYLHSNNIIYADLKPSNILIDSK------------GIFKL
...... ...|. ||           |.| | |.|.. .||..|||  |.||.||||. .            |..|.
LEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKI
Kinase DDB0230007.AA Ciliate-E2b 68-102 54 1.1e-12 35.06 In-house 109-143 (272) Show / Hide 
Range on Protein: 68-102
Range on HMM: 109-143/272
Sequence Identity: 54% (19 aa)

KNIMNALYYLHSNNIIYADLKPSNILIDSKGIFKL
. |. .| |||..|||| |.||.||..|.||  ||
ASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKL
Kinase DDB0230007.AA AktR 168-266 29 1.6e-12 44.82 In-house 170-268 (268) Show / Hide 
Range on Protein: 168-266
Range on HMM: 170-268/268
Sequence Identity: 29% (32 aa)

YLSPEVLKG-YTYSFSSDIWSFGVLLFKCITGYYPFYS-NDATKLIESIIYD-NYLDPIIRLPSDNNDLIQQQHFNDLISKILEKNPQKRIT-----WPK
|..||...    . .|.|.|.||....  .||. |||. |. ....  .|.. |. .. . . |   ||||         |.| |||.||..     |  
YMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQR--------KLLCKNPNKRLGYYCNGWEE

LFIHPFF
.  ||.|
IKSHPWF
Kinase DDB0230007.AA RSK 168-214 31 1.6e-11 38.73 In-house 174-227 (278) Show / Hide 
Range on Protein: 168-214
Range on HMM: 174-227/278
Sequence Identity: 31% (17 aa)

YLSPEVLK----GYTYSFSSDIWSFGVLLFKCITGYYPFYS---NDATKLIESI
|. ||.||    . ... . |.||.|||..   ||. ||..   |.. .... |
YMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRI
Kinase DDB0230007.AA Pkinase 47-102 29 1.8e-11 41.64 Pfam 90-153 (293) Show / Hide 
Range on Protein: 47-102
Range on HMM: 90-153/293
Sequence Identity: 29% (19 aa)

SFKEFLN--SDQYL--SIDTSIIFSKNIMNALYYLHSNNIIYADLKPSNILIDSKGIF----KL
. ....   ..  .  | .. . . . |  .|.|.||..||. ||||.|||||..|      |.
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKI
Kinase DDB0230007.AA ULK 48-102 27 4e-11 35.79 In-house 104-179 (324) Show / Hide 
Range on Protein: 48-102
Range on HMM: 104-179/324
Sequence Identity: 27% (21 aa)

FKEFLNSDQYLSIDT----------SIIFSKNIMNALYYLHSNNIIYADLKPSNILIDSK------------GIFKL
...... ...|.  |           |.| | |.|.. .||..|||  |.||.||||  .            |..|.
LEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKI
Kinase DDB0230007.AA Ciliate-E2b 167-202 34 5.1e-11 29.88 In-house 170-210 (272) Show / Hide 
Range on Protein: 167-202
Range on HMM: 170-210/272
Sequence Identity: 34% (14 aa)

YYLSPEVLK-----GYTYSFSSDIWSFGVLLFKCITGYYPF
.|. ||...     |  |....||||.|. |.  . || |.
HYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPW
Kinase DDB0230007.AA RSK 69-98 45 1.1e-07 24.58 In-house 112-144 (278) Show / Hide 
Range on Protein: 69-98
Range on HMM: 112-144/278
Sequence Identity: 45% (15 aa)

NIMNALYYLHSNNIIYADLKPSNILIDS---KG
.|  |. .||.  ||. ||||.||| |.    |
EIVLAVEHLHQQGIIHRDLKPENILYDDESNEG
Kinase DDB0230007.AA AktR 73-98 66 1.1e-07 26.07 In-house 113-139 (268) Show / Hide 
Range on Protein: 73-98
Range on HMM: 113-139/268
Sequence Identity: 66% (18 aa)

ALYYLHSN-NIIYADLKPSNILIDSKG
|| |||.. |||| |||| |||.|. |
ALEYLHQHMNIIYRDLKPENILLDEDG
Kinase DDB0230007.AA CAMK 50-109 28 5.1e-07 17.89 In-house 169-235 (425) Show / Hide 
Range on Protein: 50-109
Range on HMM: 169-235/425
Sequence Identity: 28% (20 aa)

EFLNSDQYLSIDTSIIFSKNIMNALYYLHSNNIIYADLKPSNILIDSKG----------IFKLNSINNSI
... .. ... .    . . |  |. |.||.||.  |||| |||.|...          || . . || |
DIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIF-D-WNNNNI
Kinase DDB0230007.AA Pkinase_Tyr 169-193 40 3e-06 21.74 Pfam 181-205 (270) Show / Hide 
Range on Protein: 169-193
Range on HMM: 181-205/270
Sequence Identity: 40% (10 aa)

LSPEVLKGYTYSFSSDIWSFGVLLF
..||... . ..  ||.||||||..
MAPECINYGKFTTKSDVWSFGVLMW
Kinase DDB0230007.AA RSK 241-266 35 7e-06 17.78 In-house 248-278 (278) Show / Hide 
Range on Protein: 241-266
Range on HMM: 248-278/278
Sequence Identity: 35% (11 aa)

DLISKILEKNPQKRIT-----WPKLFIHPFF
|||.| |...|.||..        .  ||.|
DLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
TyrKc DDB0230007.AA TyrKc 5-266 13 4.7e-05 -140.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-266
Range on HMM: 1-280/280
Sequence Identity: 13% (45 aa)

ESF-----------------------KRIKSDHQNQNQDQINYVDENVK-ENL--STYYLVKRISFEYSF----------------------KEFL-NSD
 ..                       | .|.|.      .    .|     .|  .   .|. .    .                       |..| .. 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

QYLSIDTSIIFSKNIMNALYYLHSNNIIYADLKPSNILIDSKGIFKLNSINNSILIENNNNNNNNNNNNNNNNNNNNNNNQQIMIT----SRQQIFNLYN
  |. .. . |.  | .   ||||.|.|  ||   |.|.....                                      .. |.    ||    ..|.
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------------------------------------TVKISDFGLSR----DIYD

N-----NIDNDNNN---NIN--ESIYYLSPEVLKGYTYSFSSDIWSFGVLLFKCITGYYPFYSN------DATKLIESIIYDNYLDPIIR-LPSDNNDLI
      . |        . .    |  ..||... ..... ||.|||||...   |   . |..      ... .|| .   .....    .       .
DDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----P-M

----QQQHFNDLISKILEKNPQKRITWPKLFIHPFF
      .   .....  . .| .| |   .  | .|
SFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DDB0230007.AA Ciliate-E2b 241-266 32 0.000124 10.19 In-house 245-272 (272) Show / Hide 
Range on Protein: 241-266
Range on HMM: 245-272/272
Sequence Identity: 32% (9 aa)

DLISKILEKNPQKRI--TWPKLFIHPFF
.|... |.|.|. |   ..  |  ||.|
KLMLQCLQKMPEVRLGGSYSWLKSHPWF