Gene YakA (Slime mold)
YakA
Sequence
Protein domains of YakA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | YakA.AA | YAK | 205-548 | 63 | 5.5e-293 | 979.61 | In-house | 1-347 (347) | Show / Hide |
Range on Protein: 205-548 Range on HMM: 1-347/347 Sequence Identity: 63% (222 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQHDPEDKN---HILRLLDSFIHKMHLCIVFELLSVNLFELIKQNNF |.|||.||||||||||||.||||.||.|.|..||.||||||...|||.|..||.||||..|| ||||..|.|.||.|.|.|||.||.||.|..|||.| YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF RGLSTNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSPAIKIIDFGSACYEKSTLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELFL .|.|..||.....||||...||.|..|||||||||||.|...|.|.||||||||.|.||...|||||.|||||||..|...||.||||||||||.||||| CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFL GLPLFPGNSEYNQISRIVEMRGIFPSDLLDKGKSSTRYFHRHLGSNSDDNNNNNNNNNGKPYYYTLKSEEDYQRDSKTTLLPSKKYFNYKTLPEIIQNYG |||.||||||||||.||..|.|..||...|.|.....|||.|.|||||||||||||||||||||..|...|||.|.|..|..||.||.||.|..|..... GLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYFHCHDGSNSDDNNNNNNNNNGKPYYYIFKTKQDYQIDEKIQLKESKTYFQYKCLNDIKNYMY FKKSMSPQDIEKEKQHRIVFTDFINGLLQLDPNERWSPMQAKEHPFI ||..|..||..|...||..|.||||.||||.|.|||.||||..|||| FKQFMRNQDDTKNNRHRDCFIDFINQLLQLNPRERWKPMQAMQHPFI |
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Kinase | YakA.AA | DYRK | 205-548 | 41 | 1.3e-173 | 583.09 | In-house | 1-320 (320) | Show / Hide |
Range on Protein: 205-548 Range on HMM: 1-320/320 Sequence Identity: 41% (146 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQHDPEDKNHILRLLDSFIHKMHLCIVFELLSVNLFELIKQNNFRGL |..|. .|.|.|||||||... |.|.|||||..|......|. ||. |. ||.| ||.|| |.....|.|.|..|||||||||| ||.|..|.|.|.|. YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGF -STNLIKVFLIQILDALIVLANA-NIIHCDLKPENILLQNV-NSPAIKIIDFGSACYEKSTLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELFL | ||...|. |||..| .|.. ||||||||||||.|.. | ..||.|||||.|.|. ..|||||||.||.|||..|. || .||||||||| ||||. FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFT GLPLFPGNSEYNQISRIVEMRGIFPSDLLDKG--KSSTRYFHRHLGSNSDDNNNNNNNNNGKPYYYTLKSEEDYQRDSKTTLLPSKKYFNYKTLPEIIQN | |||||..||.|. .|.|..|..|....||| . ...| . . ......... ....|...|. |. . . GWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC--------------------------FMYCECDEWTKQNKITDHYMTPKCHPTKR-G YGFKKSMSPQDIEKEKQHRIVFTDFINGLLQLDPNERWSPMQAKEHPFI .. ......| ... .... |.|||...||.||..|..|.|| .||.. QRRPPGRRNWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF |
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Kinase | YakA.AA | CMGC | 205-548 | 21 | 4.7e-110 | 362.98 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 205-548 Range on HMM: 1-513/513 Sequence Identity: 21% (118 aa) YKVLDSLGQGTFGQVVKCKN--------------CDTDELVAIKILKNKQAYFQQGR-------------LEIQTLKSLNDQHDPED-----------KN |.... .|.||.|.|.||.. ..|.|.||||..||.. | |.. ||. || ||..||| . .| YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN HILRLLDSFIHKM-----------------HLCIVFELLSVNLFELIKQNN--------------------------FRGLSTNLIKVFLIQILDALI-- .|..|.|.| || ||..|||.. .|...||.|. . .. .|. . ||| .| NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK VLANAN--IIHCDLKPENILLQNVNS------------------PAIKIIDFGSACYEKST------------------------LYTYIQSRHYRSPEV . .. |||.||||||||. . . .||.|||.|... . ...|...|.||.||. YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI LVG----------TVYCASIDMWSLGCISAELFLG--------LPLFPGNSE-----------YNQISRIVEMRGIFPSDLLDKGKSS------TRYFHR |.| . |. .|||||.||| ||...| |||||.|| ..|. .|... | .. ...|||.. .. . LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPN HLG--------------------SNSDDNNNNNNNNNGKPYYYTLKSEEDYQRDSKT-------------TLLPSKKYFNYKTLPEIIQNYGFKKSMSPQ ... | . | ..||. ..... ..|. . ... . .| .|| . MIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSH-KFN-------------------H DIEKEKQHRIVFTDFINGLLQLDPNERWSPMQAKEHPFI ..|.|. . |.....||.||..|... || .||.. -QFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF |
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Kinase | YakA.AA | DYRK2 | 205-440 | 46 | 1.1e-100 | 328.2 | In-house | 1-240 (318) | Show / Hide |
Range on Protein: 205-440 Range on HMM: 1-240/318 Sequence Identity: 46% (112 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQHDPEDKNHILRLLDSFIHKMHLCIVFELLSVNLFELIKQNNFRGL | .| .|.| ||||||| |...||||.. ||. . .| ||. |. . ..|. . ..||.|. |.||.|||||.|| |.||.|.| |. YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIR-RQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGF STNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSPAIKIIDFGSACYEKS-TLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELFLGL | .|. | .|| .| | |||||||||||||| | ||.||||| |.|. .||||||| ||.||| .|. | .|||||.||| |||. | SLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGY PLFPGNSEYNQISRIVEMRGIFPSDLLDKG----KSSTRYF ||||| | |. . | |. |....|. .. ..|| PLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYF |
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Kinase | YakA.AA | HIPK | 205-548 | 38 | 5.2e-96 | 302.86 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 205-548 Range on HMM: 1-329/329 Sequence Identity: 38% (133 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQHDPEDKNHILRLLDSFIHKMHLCIVFELLSVNLFELIKQNNFRGL | ||. ||.||||||||| |.|.|||||||| | ||. |.. |. | .. | |..| .. | || | |.|||.| ||.. |||.| | YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQEN--ADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPL STNLIKVFLIQILDALIVLANANIIHCDLKPENILL-QNVNSP-AIKIIDFGSACYE-KSTLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELFL . |. | |.| ||. | . .|| |||||||.| . | .|.|||||| . | ||.|||.|| ||...| .| ..|||||||. ||||| PLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFL GLPLFPGNSEYNQISRIVEMRGIFPSDLLDKGKSSTRYFHRHLGSNSDDNNNNNNNNNGKPYYYTLKSEEDYQRDSKTTLLPSKKYFNYKTLPEIIQNYG | ||.||..||.|| | . . || .. ..|.|.| . | .. || |.. .. .. .|| . | .. .. GWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRD--------------KQSKFRPWRLKHIEEHEQQTSVKSKEARKYI-FNCLDDMPEVN- FKKSMSPQDIEKEKQHRIVFTDFINGLLQLDPNERWSPMQAKEHPFI .|| || | | . .. .|...| .|..| .|||. MLVDPERQDYRVEKIDRREFVHVLKKMCTWDAHKRITPCEALNHPFV |
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Kinase | YakA.AA | DYRK1 | 205-442 | 48 | 3.2e-94 | 319.31 | In-house | 1-239 (321) | Show / Hide |
Range on Protein: 205-442 Range on HMM: 1-239/321 Sequence Identity: 48% (116 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQHDPEDKNHILRLLDSFIHKMHLCIVFELLSVNLFELIKQNNFRGL |.. ..|.| |||||| . |.|||||.|||.....| ..||. | .| .||.|.| .|..| |... |||.|||||| ||..|.. .||| YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMN-KHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGV STNLIKVFLIQILDALIVLA--NANIIHCDLKPENILLQNVNSPAIKIIDFGSACYEKSTLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELFLG | ||.. | |.. ||. .. .||||||||||||| | |||||||||.| .| ||||| |||||||.|. | .||||||||| |. | SLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTG LPLFPGNSEYNQISRIVEMRGIFPSDLLDKGKSSTRYFHR ||| | .| |...|||. |. |....|.. . .||.. EPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEK |
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Kinase | YakA.AA | S_TKc | 205-548 | 24 | 4.3e-82 | 279.96 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 205-548 Range on HMM: 1-231/231 Sequence Identity: 24% (87 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQHDPEDKNHILRLLDSFIHKMHLCIVFELLSV---NLFELIKQNNF |..|. .|.|.||.| ||.. .|...|||||.| .. | ||| ||. . .| .|.|.| . ||..|.|... .||..||... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR RG----LSTNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSPAIKIIDFGSACYEKSTLYTYIQSRHYRSPEVLVGTVYCA-SIDMWSLGCIS .| .. .. .. ||..|| . . .|||.||||||||| . |||.|||.|. .|.. ...|..|||| | ..|.||.||| HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL AELFLGLPLFPGNSEYNQISRIVEMRGIFPSDLLDKGKSSTRYFHRHLGSNSDDNNNNNNNNNGKPYYYTLKSEEDYQRDSKTTLLPSKKYFNYKTLPEI .|.. | |.|| ..... ... YEMLCGYPPFP---QMQMMFKKIG---------------------------------------------------------------------------- IQNYGFKKSMSPQDIEKEKQHRIVFTDFINGLLQLDPNERWSPMQAKE-------HPFI . |||...|| ||..|.. .| . ||.. ---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | YakA.AA | Pkinase | 205-548 | 25 | 2.8e-64 | 224.65 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 205-548 Range on HMM: 1-293/293 Sequence Identity: 25% (96 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRL-----EIQTLKSLNDQHDPEDKNHILRLLDSFIHKMHLCIVFELLSV-----NLFE |... .|.|.||.| ||.. .| ..||.||.| . . .. . ||| .|.|| |. .|.||.|.| | |...|.|.. ||. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HP-----NIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD LIK---QNNFRGLSTNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSP--AIKIIDFGSAC---YEKSTLYTYIQSRHYRSPEVLV-GTVYCA .|. ...| .| . .| .. ||| .| . . .|||.||||||||. | . . .||.|||.|. | .....|. ...|..|||. |. | YISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGP SIDMWSLGCISAELFLGLPLFPGN----SEYNQISRIVEMRG---IFPSDLLDKGK--SSTRYFHRHLGSNSDDNNNNNNNNNGKPYYYTLKSEEDYQRD ..||||.||| .|...| |.||| . ..|. .|.. .| |... .. . . .|. | KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------------------------------- SKTTLLPSKKYFNYKTLPEIIQNYGFKKSMSPQDIEKEKQHR--IVFTDFINGLLQLDPNERWSPMQAKEHPFI . .... |. . |||...|..||..|....|...||.. ---------------------------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | YakA.AA | PRP4 | 205-440 | 36 | 2.4e-63 | 216.75 | In-house | 1-239 (320) | Show / Hide |
Range on Protein: 205-440 Range on HMM: 1-239/320 Sequence Identity: 36% (87 aa) YKVLDSLGQGTFGQVVKCK-NCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQ-HDPEDKNHILRLLDSFIHKMHLCIVFELLSVNLFELIKQN-NF |.| ||| |. |..|. . . | |||||. |. . | |. |. |||. |..|| |..|. ..| |. |.|.||| .| || |..|. YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD RGLSTNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSPAIKIIDFGSACY-EKSTLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELF ||. . . .. |.. || | . ||.| |.|| ||| | . .|..||||| . . . | .|| ||.||...| | ..||||| || .||. VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILV-NESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELY LGLPLFPGNSEYNQISRIVEMRGIFPSDLLDKGKSSTRYF | .||| . . . ...| .| .. ||. .| TGKIMFPGKTNNHMLKLFMDYKGKMPNKMIRKGQFKDNHF |
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Kinase | YakA.AA | CDK | 205-548 | 23 | 1.2e-59 | 189.42 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 205-548 Range on HMM: 1-284/284 Sequence Identity: 23% (91 aa) YKVLDSLGQGTFGQVVKCKNCDTD-----ELVAIKILKNKQ---AYFQQGRL-----EIQTLKSLNDQHDPEDKNHILRLLDSFIHK-----------MH |. |. .|.||.|.| |... .|. ..||.| .. . | || .|| | |. .| .|.| ...| YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL---HP-----NIVKLHDVCHTKNMDRNNKDKHENK LCIVFELLSVNLFELIKQNNFRGLSTNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSPA---IKIIDFGSACYE--------KSTLYT-YIQ | .||| . | .... || .. |.|..| . .|.| |||| |||. | .. .|| ||| |. .. || . LYMVFEYMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVV SRHYRSPEVLV-GTVYC--ASIDMWSLGCISAELFL---GLPLFPGNSEYNQISRIVEMRGIFPSDLLDKGKSSTRYFHRHLGSNSDDNNNNNNNNNGKP . ||.||.| . | .|||||.||| ||.|. . |||||.|| .|. .| .. | | .. | TLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------- YYYTLKSEEDYQRDSKTTLLPSKKYFNYKTLPEIIQNYGFKKSMSPQDIEKEKQHRIVFTDFINGLLQLDPNERWSPMQAKEHPFI |..|..|..||. |.| || .||. ------------------------------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF |
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Kinase | YakA.AA | DyrkP | 205-443 | 39 | 4e-54 | 176.34 | In-house | 1-242 (323) | Show / Hide |
Range on Protein: 205-443 Range on HMM: 1-242/323 Sequence Identity: 39% (95 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQHDPEDKNHILRLLDSFIHKMHLCIVFELLSVNLFELIKQN----N |.... || | . ..|. |. .. .||. | . || | ||. |. .| | ..|| .|| | | || || |. ||| ||.| | | YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKN-VLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQ FRGLSTNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSPAIKIIDFGSACYEKSTLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELF | .. ||| || . .|||||||||||.. .|||||||.|. | |.||| || |||..| | ||||||||| |||. QRYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELW LGLPLFPGNSEYNQISRIVEMRGIFPSDLLDKGKSSTRYFHRH | || . |.. . | || .. |. .| |. TGNVLFQNDNIQGLLARVIGIIGPFPEWMMQEGRLVQNFFTRK |
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Kinase | YakA.AA | CLK | 205-340 | 32 | 2.7e-48 | 142.47 | In-house | 1-147 (350) | Show / Hide |
Range on Protein: 205-340 Range on HMM: 1-147/350 Sequence Identity: 32% (48 aa) YKVLDSLGQGTFGQVVKCKNCDT-DELVAIKILKNKQAYFQQGRLEIQ-TLKSLNDQHDPEDKNH--ILRLLDSFIH-KMHLCIVFELLSVNLFELIKQN |.... ||.|||| ||.|. . .||.|| .| | . ..||. .|..| |||. |. .....|.| . . | ||||||. ......| | YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN N------FRGLSTNLIKVFLIQILDALIVLANANIIHCDLKPENILL | .... . |... |.. |. | ..| |||||||.. NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICF |
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Kinase | YakA.AA | CLK | 341-411 | 37 | 2.5e-21 | 60.04 | In-house | 179-252 (350) | Show / Hide |
Range on Protein: 341-411 Range on HMM: 179-252/350 Sequence Identity: 37% (28 aa) QNVNSPAIKIIDFGSAC---YEKSTLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELFLGLPLFPGNSE . | .. |..|||||| ... .| ...|||| ||| | . | || ||| || .| ||..... WHVKNTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDN |
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Kinase | YakA.AA | TyrKc | 205-528 | 15 | 2.4e-08 | -87.74 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 205-528 Range on HMM: 1-280/280 Sequence Identity: 15% (57 aa) YKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSL--NDQHDPEDKNHILRLLDSFIHK-------MHLCIVFELLSV-NLFE . .. || | ||.|.|.. . ||.| ||. . . |.. ...| . . .|.||. ... |.||.|. . .| . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHP-------NIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD LIKQNNFRGLSTNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSPAIKIIDFGSACYEKST-------LYTYI----QSR-----HYRSPEVL .. . . |.. | .|| . |. |.|| || |.|. . . .|| ||| . . .. | ... .||.. YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI VGTVYCASIDMWSLGCISAELF-LGLPLFPG-----NSEYNQISRIVEMRGIFPSDL----LDKGKSSTRYFHRHLGSNSDDNNNNNNNNNGKPYYYTLK .. | || | |.| .| . || | . | .. . . . . NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------------- SEEDYQRDSKTTLLPSKKYFNYKTLPEIIQNYGFKKSMSPQDI--------EKEKQHRIVFTDFINGL | |... . . | |.. . . ---------------------------------F--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | YakA.AA | PRP4 | 509-548 | 34 | 4.6e-08 | 25.68 | In-house | 280-320 (320) | Show / Hide |
Range on Protein: 509-548 Range on HMM: 280-320/320 Sequence Identity: 34% (14 aa) QDIEKEKQHRIV-FTDFINGLLQLDPNERWSPMQAKEHPFI | | .. . .. | |.. ..|.||| | .. .| .|||| QRIPEDQMKKVHQFKDLLDKCLMLDPKKRITCNEALKHPFI |
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Kinase | YakA.AA | DYRK2 | 521-548 | 50 | 8.9e-07 | 17.71 | In-house | 291-318 (318) | Show / Hide |
Range on Protein: 521-548 Range on HMM: 291-318/318 Sequence Identity: 50% (14 aa) FTDFINGLLQLDPNERWSPMQAKEHPFI |.||| .. || || .| || .||.| FIDFIKRCFEWDPSERMTPSQALKHPWI |
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Kinase | YakA.AA | DYRK1 | 521-548 | 42 | 1.7e-05 | 14.7 | In-house | 294-321 (321) | Show / Hide |
Range on Protein: 521-548 Range on HMM: 294-321/321 Sequence Identity: 42% (12 aa) FTDFINGLLQLDPNERWSPMQAKEHPFI | | | .|| ||..| .|..| .|.|. FKDLIKRMLQYDPKQRITPYYALQHSFF |
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Kinase | YakA.AA | DyrkP | 520-548 | 34 | 0.000561 | 8.23 | In-house | 295-323 (323) | Show / Hide |
Range on Protein: 520-548 Range on HMM: 295-323/323 Sequence Identity: 34% (10 aa) VFTDFINGLLQLDPNERWSPMQAKEHPFI .| ||. .||.| | . | .||.. MFIDFVRQCLQIDFTRRPTAKEALQHPWF |
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Kinase | YakA.AA | Pkinase_Tyr | 205-239 | 33 | 0.000796 | 13.58 | Pfam | 1-39 (270) | Show / Hide |
Range on Protein: 205-239 Range on HMM: 1-39/270 Sequence Identity: 33% (13 aa) YKVLDSLGQGTFGQVVKCKNC----DTDELVAIKILKNK . . ||.| ||.|.|.. .|. ||.|.||.. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG |
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Kinase | YakA.AA | CLK | 501-548 | 35 | 0.002684 | 4.94 | In-house | 308-350 (350) | Show / Hide |
Range on Protein: 501-548 Range on HMM: 308-350/350 Sequence Identity: 35% (17 aa) GFKKSMSPQDIEKEKQHRIVFTDFINGLLQLDPNERWSPMQAKEHPFI ..|..|...| | ||. | | | .| ||. | . .| ||| PLKQYMDCKDPE----HRQLF-DLIRKMLEYDPSKRITCKDALQHPFF |