Gene DDB0229428_C2d (Slime mold)

DDB0229428_C2d

Species: Slime mold
Alias: DDB0229428_C2d, DdisK289, DDB0217274
External Links: DictyBase Link ,
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7

Sequence

Name Sequence Type Origin Length Description Download
DDB0229428_C2d.AA Protein None 694 None Fasta, JSON
DDB0229428_C2d.kin_dom Protein Kinase Domain None 300 None Fasta, JSON

Protein domain

Protein domains of DDB0229428_C2d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229428_C2d.AA CRK7 209-508 57 7.4e-235 786.51 In-house 1-343 (343) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-343/343
Sequence Identity: 57% (198 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMDNE---VEGFPITAIREIKILKELNHANVVNLKEVVTSK--ASASNNHKGSVYMVFEYMDHDLNGL
.|.|.||||||.|||||||||..|..||||||.||||   .||||||||||||||..|||.|.|||||.||.|  ||....||||.|||||||||||.||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MDSPAFKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSSEKKQILTNRVITLWYRPPELLLGTFHY--------
..|.....|...|.||..||||||.||||..|.||||||.||.|..|.|..|.|||||||..||.||....|||||||||||||||||...|        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------GPEIDMWSVGCIMAELLSKKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPKREYNSLSL
                              ||||||||.|||..||..||..|.|.|...||.|||..|||||.|||||.|.||.|...||||.||....
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

KDFYQHENPSFFTKEAFDLLDKLLCMDPKKRITASEALDHQYF
..||.|..|.|..||..|||||.||.|||||.||.|.|.|..|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase DDB0229428_C2d.AA CDK 209-508 48 9.5e-179 576.68 In-house 1-284 (284) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-284/284
Sequence Identity: 48% (158 aa)

HEKIEQIGEGTFGQVYKAKNKSNG-----DIVALKKVIMDN-----EVEGFPITAIREIKILKELNHANVVNLKEVVTSKASASNNHKG----SVYMVFE
 ||.|.|||||.|.||||..| .|     .||||||..|.|     | |||||||||||..|||| |.|.|.|..|...|....|| |.    ..|||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YMDHDLNGLMDSPAFKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGI-----LKLADFGLARPFN-----SSEKKQILTNRVITLWYR
|||||| ..||           ||||..|||.||.|||.|...|||.| .|.|..|||.     ||.||||||| |.     | |. . .|..|.|||||
YMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYR

PPELLLGTFHYG--PEIDMWSVGCIMAELLS---KKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPKREYNSLSLKDFYQHENPSFFTK
.||||||. ||.  ..|||||||||.||..    .| ||||.. ||||.|| ..||.|. .|||.  .|| .                            
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------------

EAFDLLDKLLCMDPKKRITASEALDHQYF
   |||.|.||.||||||.|..||.|.||
---DLLNKMLCYDPKKRISAEQALQHPYF
Kinase DDB0229428_C2d.AA CMGC 209-508 26 1.2e-143 475.48 In-house 1-513 (513) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-513/513
Sequence Identity: 26% (139 aa)

HEKIEQIGEGTFGQVYKAKN--------------KSNGDIVALKKVI---MDN------EVEGFPITAIREIKILKELN-----------------HANV
 |.|..|||||.|.|||...              . .. |||.||.    ...      | .||||.|.|||||||.||                 | |.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNLKEVVTSKASASNNHK---------GSVYMVFEYMDHDLNGLMDSPAF-------KYFAPGQ------------IKCYL------KQLLEGLD--YCH
|.|......| |..|. .          ..|.||||||||| .....  |       ... . .            ||...      .|.|.||.  |||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

RNN--VLHRDIKGSNLLLDNN--------------------GILKLADFGLARPFNSSEKK-------------------QILTNRVITLWYRPPELLLG
...  ..|||.| .|.|...|                    |.||..|||||| ... ...                   . .|..| |.|||.||.|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

TFHY---------GPEIDMWSVGCIMAELLSK--------KTLFPGRNS-----------IDQLDKIYQVCGSPN---------------ANNWPEAMDL
  ||         ...|||||||||.||.. .        |.||||...           ||||.|| .|.|.|.                ..||.  .|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

P----------------FWDAL----------KPKREYNSLSL-----------------------KDFYQHENPSFFT---------KEAFDLLDKLLC
|                .|.            .|.. .....                        ..| .| .  |           ..|.|||.|.|.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSH-K--F-NHQFKRKCCDPQAIDLLKKMLQ

MDPKKRITASEALDHQYF
.||.|||||..||.| ||
YDPDKRITAEQALQHPYF
Kinase DDB0229428_C2d.AA CDC2 209-508 43 2.5e-139 431.14 In-house 1-301 (301) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-301/301
Sequence Identity: 43% (137 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMDNEVEG--FPITAIREIKILKELN-HANVVNLKEVVTSKASASNNHKGSVYMVFEYMDHDLNGLMD
 .||| |||||.| |||.|..  ..||||||.  ..| ||  .| |||||| .||||. | |.| |..|. .          ..||||||.|.||  .||
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---------NKLYMVFEYLDMDLKKYMD

--SPAFKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSSEKKQILTN-RVITLWYRPPELLLGTFHYGPEIDMW
   |  |.. |  .| |..|.|.|...||.. ..|||.| .|.|.|..| .|.||||||| |.   .....|.  |.|||||.||.|||  .|  ..|||
MSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFG-IPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMW

SVGCIMAEL---LSKKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPKREYNSLSLKDFY---QHENPSFFTKEAFDLLDKLLCMDPKKR
|.|||.||.    .|| ||.|   |||| || .. |.|| ..||.  .|| . .  |. . . ||        . .  |. ..|..|||...|. || ||
SIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQ-SCLDPEGIDLLMQMLQYDPQKR

ITASEALDHQYF
|.| |||.| ||
ISAKEALQHPYF
Kinase DDB0229428_C2d.AA PITSLRE 209-508 44 6.9e-133 447.77 In-house 1-295 (295) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-295/295
Sequence Identity: 44% (137 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMD--NEVEGFPITAIREIK-ILKELNHANVVNLKEVVTSKASASNNHKGSVYMVFEYMDHDLNGLMD
 ... .|.|||.| ||.||.|  ..|||||.. |.   | ||||||..|||. ||..|.| |.||.||.|  .       . ..|||.||..||| .||.
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGS------NMDKIYMVMEYVEHDLKSLME

SPA--FKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSSEKKQILTNRVITLWYRPPELLLGTFHYGPEIDMWS
      . | ||.||| . ||| | .. | | ..||| | ||||. ..||||..|||||| . |  |.  .|  |.||||| ||||||.  | . .||||
NMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKP--YTPCVVTLWYRAPELLLGCKKYSTPVDMWS

VGCIMAELLSKKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPKREYNSLSLKDFYQHENPSFFTKEAFDLLDKLLCMDPKKRITASEAL
||||.||....| ||.|.. |||...| .  | |.   ||   .|| | ...  ..|    |.   . ||    .  .|||| ..|. .||.|||||.||
VGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAEN--HISDTGFDLLNQMLTYNPKNRITASDAL

DHQYF
.| .|
KHPWF
Kinase DDB0229428_C2d.AA CDK7 209-508 40 4e-128 343.43 In-house 1-288 (288) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-288/288
Sequence Identity: 40% (124 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVI----MDNEVEGFPITAIREIKILKELNHANVVNLKEVVTSKASASNNHKGSVYMVFEYMDHDLNGLM
 |||..||||.|. ||||  .. | ||| ||.      .    |   |||||||||.|. | ||..|  .          || ....||..|| ||    
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFM--------HKSNIQLVFDFMDWDLEVVI

DSPAFKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSSEKKQILTNRVITLWYRPPELLLGTFHYGPEIDMWSV
       . |  || | ...| || ||||| .||||.|  |||.. ||.||.||||||| . |  .  |.|  |.| ||| |||| |  |||. .|||||
KDKSI-ILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNR--IYTHQVVTRWYRAPELLFGARHYGTGVDMWSV

GCIMAELLSKKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPKREYNSLSLKDFYQHENPSFFTKEAFDLLDKLLCMDPKKRITASEALD
|||.|||.     .|| . |||| .|.|  | |.  .||.   ..    .|.  .|    |.. .     .  . .. ||. ... |.| ||.|....| 
GCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIF-----TAASDDLLDLMCGMWTMNPCKRWTCTQCLK

HQYF
. ||
MPYF
Kinase DDB0229428_C2d.AA CDK9 209-508 43 6.4e-120 404.69 In-house 1-340 (340) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-340/340
Sequence Identity: 43% (148 aa)

HEKIEQIGEGTFG-----------QVYKAKNKSNGDIVALKKVIMDNEVEGFPITAIREIKILKELNHANVVNLKEVVTSKASASNNHKG--SVYMVFEY
 ||.  || ||||            |.||. | |. .||.||| |.|| ||||||| ||||.|. | | ||||| |.   ||.| |  |.  ..|.||..
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFDF

MDHDLNGLMDSPAFKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPF----NSSEKKQILTNRVITLWYRPPELLLG
 .||| ||.  .  | |  | ||  ...|. || | ||| .|||| |  | |   .||||||||||||.|    |..    . ||||.||||||||||||
CEHDLAGLLSNMNVK-FSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLG

TFHYGPEIDMWSVGCIMAELLSKKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDAL-------KPKREYNSLS--LKDFYQ------------
   ||| ||||  ||||||.        |     ||  | | ||| . . ||   ... |...        ||  .  .   .| . .            
DRNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSKTDPFG

---HENPSFFTKEAFDLLDKLLCMDPKKRITASEALDHQYF
    .  |    .| .|.|||| .|||||... ||||| .|
KNVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF
Kinase DDB0229428_C2d.AA CDK5 209-508 45 4.1e-115 365.29 In-house 1-287 (287) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-287/287
Sequence Identity: 45% (136 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMDNEVEGFPITAIREIKILKELNHANVVNLKEVVTSKASASNNHKGSVYMVFEYMDHDLNGLMDSPA
.||.| |||||.| ||||.||  . |||||.| .|.| || | |||||| .|||| | |.| |  |. |      . |    .|||..| ||   |||  
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHS------EKK--LTLVFEFCDQDLKKYMDSCN

FKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSSEKKQILTNRVITLWYRPPELLLGTFHYGPEIDMWSVGCIM
  .  .  || .. ||| || .|| ..||||| |  |||   ||.|||||||||| |    .    .  |.|||||||  |.|  ||   |||||.|||.
G-EMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVR--CYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIF

AELL-SKKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPKREYNSLSLKDFYQHENPSFFTKEAFDLLDKLLCMDPKKRITASEALDHQY
||.  . . |||| .  ||| .|... |.|. ..||   .|| . ..    .| .  ..  .|   |.   ..  ||| |.| ..|..||.| .|| |.|
AEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPN--HQQYPMYPAHQSWQQIVPK-LDEKGMDLLQKMLQCNPNQRISAKAALHHPY

F
|
F
Kinase DDB0229428_C2d.AA S_TKc 209-508 29 2.7e-103 350.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-231/231
Sequence Identity: 29% (93 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMDNEVEGFPITAIREIKILKELNHANVVNLKEVVTSKASASNNHKGSVYMVFEYMDH---DLNGLMD
 |....||.|.||.|||...|. | |||.|..          ....|||.|||. .| |.|.|..|  .         ...|||.||.|.   ||  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIK

SPAF----KYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSSEKKQILTNRVITLWYRPPELLLGTFHYGP-EID
.       ..| . ....|..|....|.|||.....|||.| .|.|||.   .|..|||||| .         |  . |.||..||.|    .||. ..|
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKCD

MWSVGCIMAELLSKKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPKREYNSLSLKDFYQHENPSFFTKEAFDLLDKLLCMDPKKRITAS
.||.|||..|.|. ...||      |........|                                          ..|| |...|.|..||.||.|| 
WWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-

EALD-------HQYF
|||        |..|
EALQDEWDIKCHPWF
Kinase DDB0229428_C2d.AA Pkinase 209-508 34 1.3e-101 348.64 Pfam 1-293 (293) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-293/293
Sequence Identity: 34% (109 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMDNEVEGFPITAIR--EIKILKELNHANVVNLKEVVTSKASASNNHKGSVYMVFEYMDHDLNGLMDS
 .....||.|.||.|||...|..|.|||.|..  ..| .....|..|  ||.|.|.||| |.| |......        |...|||.||....|  .|| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--------KDHIYMVMEYCEGGLY-VMDL

P------AFKYF--APGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGIL----KLADFGLARPFNSSEKKQILTNRVITLWYRPPELLLGTFH
       . . |   . ..|.|..|.|.||.|||.....|||.| .|.|.|||| .    |..|||||. |.   ... .| .. |.||..||...|  .
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQY

YGPEIDMWSVGCIMAELLSKKTLFPGR----NSIDQLDKIYQVCGSPNANNWPEAMDLP--FWDALKPKREYNSLSLKDFYQHENPSFFTKEAFDLLDKL
|||..||||.|||..|.|.....|||.    | .||. .|... | |.  .||.  . .  | .   . .         |   ..    ..|. |.....
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------F-HWTF-HNWSEECKDFIKWC

LCMDPKKRITASEALDHQYF
||.|||||.|| ..| | .|
LCKDPKKRPTAEQILQHPWF
Kinase DDB0229428_C2d.AA CDK10 209-508 42 1.5e-91 310.46 In-house 1-285 (285) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-285/285
Sequence Identity: 42% (128 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMDNEVEGFPITAIREIKILKELNHANVVNLKEVVTSKASASNNHKGSVYMVFEYMDHDLNGLMDSPA
 ||.  .||||.| ||.|.     .||||||| || | .| || ..|||..|... | |.|.|.|||  .      |  |...| .| . ||  |.|   
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQ------HLDSIFLVMQYCEQDLASLLDN-M

FKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSSEKKQILTNRVITLWYRPPELLLGTFHYGPEIDMWSVGCIM
 . |.  |.||   |.| || | |.| ..|||.| ||||.  .| .|.||||||| .  .   . .| ...||||| ||||||.      |||| ||||.
PQPFTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMY--GVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCIL

AELLSKKTLFPGRNSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPKRE-YNSLSLKDFYQHENPSFFTKEAFDLLDKLLCMDPKKRITASEALDHQY
.||| .| |.||   | |.| | .. |.|. | ||   |||  .    |.  || |  | |       .  .    ||. |.  .|||| || |.|. .|
GELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHK-F------HWLSQSGRRLLNFLFMYNPKKRATAEECLESSY

F
|
F
Kinase DDB0229428_C2d.AA PFTAIRE 209-508 40 2.3e-90 306.51 In-house 1-287 (287) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-287/287
Sequence Identity: 40% (124 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMDNEVEGFPITAIREIKILKELNHANVVNLKEVVTSKASASNNHKGSVYMVFEYMDHDLNGLMDSPA
 ||.|  |||..  |||.. . |. .|||| . ...| || | |||||   ||.| |||.| |  ..  |   .        .||||.. ||   ||.  
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQE-EGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLT--------FVFEYVHTDLCQYMDK-H

FKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSSEKKQILTNRVITLWYRPPELLLGTFHYGPEIDMWSVGCIM
     |  .. .| ||| || |||.  |||||.|  |||. . | ||||||||||    |   .   . |.|||||||  |||   |  ..||| ||||.
PGGMHPNNVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLAR--AKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIF

AELLSKKTLFPGR-NSIDQLDKIYQVCGSPNANNWPEAMDLPFWDALKPK-REYNSLSLKDFYQHENPSFF-TKEAFDLLDKLLCMDPKKRITASEALDH
 |..  . .|||  .  |||.||..| |.|. . ||    || .   . . | |.. .|    .|  |.     .|.||. |.| . |..|. | ||. |
VEMMWGQPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKL----CHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQH

QYF
.||
PYF
Kinase DDB0229428_C2d.AA Pkinase_Tyr 210-363 30 1.5e-19 66.86 Pfam 2-159 (270) Show / Hide 
Range on Protein: 210-363
Range on HMM: 2-159/270
Sequence Identity: 30% (52 aa)

EKIEQIGEGTFGQVYKAKNK----SNGDIVALKKV--IMDNE---VEGFPITAIREIKILKEL-NHANVVNLKEVVTSKASASNNHKGS--VYMVFEYMD
......||| ||.|||.. |    ...  || |..    . |    | |    .||.||.|.| .| |.|.|  |.|        ....  .|.|.||| 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCT-------DQGEPNQIYIVMEYMP

H-DLNGLMDSP--AFKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLAR
| ||     ..    . . . .. ..  |  .|..| ...|  |||.   | |...|.. | .||||||
HGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase DDB0229428_C2d.AA TyrKc 209-508 21 8.7e-14 0.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 209-508
Range on HMM: 1-280/280
Sequence Identity: 21% (72 aa)

HEKIEQIGEGTFGQVYKAKNKSNGDIVALKKVIMDNEVEGFPITAIREIKILKEL--NHANVVNLKEVVTSKASASNNHK---GSVYMVFEYMDH-DLNG
 ......||| ||.|||.. |     || |..  |          .||..|...|  .| |.|.|  |.|..           . ...|.|||.| ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMPHGDLKD

LMDSPAFKYFAPGQIKCYLKQLLEGLDYCHRNNVLHRDIKGSNLLLDNNGILKLADFGLARPFNSS--------EKKQ---ILTNRVITLWYRPPELLLG
   ..  | . . .   .  |  .| .| |..|. |||.   | |...|.. | .||||.|   .          ...     .. .. .   .|| .  
YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-N

TFHYGPEIDMWSVGCIMAELLSK-KTLFPG--------RNSIDQLDKIYQVCGSPN----ANNWPEAMDLPFWDALKPKREYNSLSLKDFYQHENPSFFT
.  . .. | || |  | |...  ..  ||        .  | .... |     ||    .                            |         .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------F------VCCP

KEAFDLLDKLLCMDPKKRITASEALDHQYF
.| ...  .    ||..| | ||   |..|
DEMYQIMKQCWHEDPEDRPTFSEI--HECF