DDB0229294

Species: Slime mold
Alias: DDB0229294, DdisK049
External Links: DictyBase Link ,
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-DD1

Sequence

Name Sequence Type Origin Length Description Download
DDB0229294.AA Protein None 636 None Fasta, JSON
DDB0229294.kin_dom Protein Kinase Domain None 277 None Fasta, JSON

Protein domain

Protein domains of DDB0229294.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229294.AA CDK-DD1 64-343 45 5.9e-232 724.56 In-house 1-379 (379) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-379/379
Sequence Identity: 45% (171 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFKGWTEGDRASKEECSLLQQLRHIPYITPVIDIYTNFETSEYIIVFPYFEHDLSGLLSEHR--LSIPQV
| ||||.|.||.|||||||.|.|..||||||||.|...|...|.||..|.||||...|...||...||..|.|..||.||||||....|.|.  .|.|..
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFKDWNQEDGEPKVECKYLMQLRHCKNIVHLIDHFYNFKNSKYVMVFEYFEHDLWKFMSNHQCYMSLPCI

KCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGDLGTATSYTKR--SVFSSKVVTLWYRAPELLLGSTQYGPEIDMWSIGCVLIELVTSRNFL
||.|.||||||||.||.|.||||||.||||.||.|.|.|.|.|..|.||||  ..||..||.||||.||||.||.||||||||||.||.|.|..|.....
KCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVGCILMEMITNFYMF

PGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLP------------VYPSRLR-----------------------------------------
.||.||||||.||||||.||...||.|||||..||..|..            .||||.|                                         
AGSNEQQQLELICKLCGCPTEKNWPGVSQLQGYNQYFHKQQQQQQNENNYSKQYPSRNRNNNNNNNNNNNNNNNNNNNNNNNNNKYNNISTSCLQSPSSS

-----------TVFKN---------FSN----------------------DFIELLEGLLTLNPKKRLTAEQALQSPFF
           |.||.         |||                      .|..|.|..|||.||||.....|||.|.|
PPIGGYASSLSTDFKSNEYNGYNQTFSNEDCLAISQKKLIDKFPHLVLLPSFLDLIERMLTLCPKKRINTKEALQHPWF

Kinase DDB0229294.AA CDK 64-343 34 3.7e-133 428.46 In-house 1-284 (284) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-284/284
Sequence Identity: 34% (111 aa)

YEIISKIGEGISGSVFKAIKKGTE-----EMVALKNFKGWT-----EGDRASK---EECSLLQQLRHIPYITPVIDIYTNFETS---------EYIIVFP
||.. |||||  | |.||. | |      ..|||| .. ..     |..  .     |.|||..|   |.|  ..|...  ...            .||.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YFEHDLSGLLSEHRLSIPQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGS-----LFIGDLGTATSYT-------KRSVFSSKVVTLWYRAPEL
| .|||.....        .|||..|||.|.. .|  ..||||.| .|.|.||.|.     | |.| | |  .        .. .....|||||||||||
YMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

LLGSTQYG--PEIDMWSIGCVLIELVT---SRNFLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVYPSRLRTVFKNFSNDFIELLEGLL
||||..|.  ..|||||.||...|..|    . ..||.||. ||. |...|||||...||.|..|...                         .||...|
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKML

TLNPKKRLTAEQALQSPFF
...||||..||||||.|.|
CYDPKKRISAEQALQHPYF

Kinase DDB0229294.AA CMGC 64-343 22 7.6e-111 365.63 In-house 1-513 (513) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-513/513
Sequence Identity: 22% (114 aa)

YEIISKIGEGISGSVFKAIK--------------KGTEEMVALKNFKGWTEGDRASK-------------EECSLLQQLR----------------HIPY
||||.|||||  | |.|..               . |.|.||.| .|     ..  |              |...|..|.                | ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ITPVIDIYTNFETS---------------EYIIVFPYFEHDLSGLLSEHR----------LSIPQ------------VKCYF------KQLLEGIN--EI
|   .||..  ..                .  .|| | .||| ... ...          ||  .            .|...      .|.|.|..   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HNAG--VMHRDIKAANLLVNNK--------------------GSLFIGDLGTATSYTKRS----------------------VFSSKVVTLWYRAPELLL
| ..  ..|||.| .|.|.|..                    | | |.| | |..| ..|                       ... |||.||||||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GS---------TQYGPEIDMWSIGCVLIELVTS--------RNFLPGSSE-----------QQQLEAICKLCGTPT---------------DEIWPNVSQ
|.         ..|...|||||.||.. |..|         . . ||.||           . ||. |.|..||||               .|.|||...
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

LQNFNQISH------------------------LP-VYPSRLRTVFKNFSN-----------------------------------DFIELLEGLLTLNP
|...|.  .                        .| ..|  .. .|....|                                   ..|.||...|...|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

KKRLTAEQALQSPFF
.||.||||||| |.|
DKRITAEQALQHPYF

Kinase DDB0229294.AA CRK7 139-343 38 2.3e-86 293.2 In-house 89-343 (343) Show / Hide
Range on Protein: 139-343
Range on HMM: 89-343/343
Sequence Identity: 38% (97 aa)

VFPYFEHDLSGLLSEH---RLSIPQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGDLGTATSYTK---RSVFSSKVVTLWYRAPELLLG
|| |  |||.|||        |  |.||..||||||.. .|. ...||||| .|.|.||.| . | |.| |  | .   |  .  .|.|||||.||||||
VFEYMDHDLMGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLG

STQY--------------------------------------GPEIDMWSIGCVLIELVTSRNFLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQ
 ..|                                      |||||||| || |.|| | .. ..|. | .||| | |.||.|. . ||.| .|. .| 
EERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNT

ISHLPVYPSRLRTVFK------NFSNDFIELLEGLLTLNPKKRLTAEQALQSPFF
.     | .|||  |       ... ..  || ..|.|.|||| |||..||...|
MKPKRQYNRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF

Kinase DDB0229294.AA Pkinase 64-343 31 1.5e-81 281.99 Pfam 1-293 (293) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-293/293
Sequence Identity: 31% (97 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFKGWTEGDRASKE-----ECSLLQQLRHIPYITPVIDIYTNFETSEYIIVFPYFEH-----DLSGLLS-
|.|..|||.| .|.|.|...|||...||.| .|  .| .   ..     |..... |.| |.|   .|....   ... .|..| |.     ||. ..| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNH-PNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

--EHRL--SIPQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSL----FIGDLGTATS--YTKRSVFSSKVVTLWYRAPELLLGSTQYGPEIDM
  . ..  |  ..|.|..|.|.|.. .|. |..|||.| .|.|..|.| .     |.| | |    | . | ... ..|.||.|||...|.. |||..||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSIGCVLIELVTSRNFLPGS----SEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVYPSRLRTVFKNFSNDFIELLEGLLTLNPKKRLTAEQAL
||.||.|.|... |   ||.    .   |.. ||.  |.|... ||. .   .|. ..| .     ..|. .| | .........|...||||.||||.|
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL

QSPFF
|.|.|
QHPWF

Kinase DDB0229294.AA CDK7 161-343 41 4.5e-80 212.83 In-house 104-288 (288) Show / Hide
Range on Protein: 161-343
Range on HMM: 104-288/288
Sequence Identity: 41% (76 aa)

VKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGDLGTATSYTK-RSVFSSKVVTLWYRAPELLLGSTQYGPEIDMWSIGCVLIELVTSRNFL
.| | ...| |.   |   . |||.|  |||.|  | | |.| | | .|     .....||| |||||||| |  .||. .||||.||.. ||     .|
IKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYL

PGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVY-PSRLRTVFKNFSNDFIELLEGLLTLNPKKRLTAEQALQSPFF
|| |.  ||. |..  ||||.| |||..........   | |    || .|   |.| ..|..|..|.|| ||.|. |.|..|.|
PGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF

Kinase DDB0229294.AA S_TKc 64-343 24 1.9e-79 271.17 SMART 1-231 (231) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-231/231
Sequence Identity: 24% (72 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFKGWTEGDRASKEECSLLQQLRHIPYITPVIDIYTNFETSEYIIVFPYFEH---DLSGLLSEHR-----
|||. |||.|  |.|.|...|.| . ||.|  |      .  . | ..|..  | |.|   .|.. .   ... .|. | ..   ||  .. ...     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSIPQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGDLGTATSYTKRSVFSSKVVTLWYRAPELLLGSTQYGP-EIDMWSIGCVLIEL
  ..  ....|..|...... .|. |..|||.| .|.|...   . |.| | |. .      .. ..|.||.|||.|    .||. ..|.||.||.|.|.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

VTSRNFLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVYPSRLRTVFKNFSNDFIELLEGLLTLNPKKRLTAEQALQ-------SPFF
.. .   |      |.... |..|                                    | .........|. .|.||.|| .|||        |.|
LCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase DDB0229294.AA CDC2 64-343 34 1.9e-77 237.46 In-house 1-301 (301) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-301/301
Sequence Identity: 34% (106 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFKGW--TEGD---RASKEECSLLQQLR-HIPYITPVIDIYTNFETSEYIIVFPYFEHDLSGLLS-----
|. | |||||  | |.|.. . | ..|||| ..    .|||     .  | |.|. |. | | |.   |.. .   .   .|| | ..||  ..      
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDH-PNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPK

EHRLSIPQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGD--LGTATSYTKRSVFSS-KVVTLWYRAPELLLGSTQYGPEIDMWSIGCVL
.  ..   || |..|.|.|..  |  ..||||.|  |.|...||.. |.|  |. | .. .|       ||||||||||.|||. .|  ..|||||||..
NKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIF

IEL---VTSRNFLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVYPSR-LRTVFKN---------FSNDFIELLEGLLTLNPKKRLTAEQ
.|.   || . . .| ||  ||  | .  |||....||.|.||. ...    | ..   |.....|           .. |.||. .| ..| ||..|..
AEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNT--FPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKE

ALQSPFF
||| |.|
ALQHPYF

Kinase DDB0229294.AA PITSLRE 138-343 40 3.8e-73 249.32 In-house 80-295 (295) Show / Hide
Range on Protein: 138-343
Range on HMM: 80-295/295
Sequence Identity: 40% (88 aa)

IVFPYFEHDLSGLLSEHR-----LSIPQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGDLGTATSYTKR-SVFSSKVVTLWYRAPELLL
.|. | |||| .|.  ..      .....||   ||| |.   |   .|||| | .||| ..|| | |.| | |  |      ... |||||||||||||
MVMEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLL

GSTQYGPEIDMWSIGCVLIELVTSRNFLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVYP-SRLRTVFK---NFSNDFIELLEGLLTLN
|.  | . .||||.||.. |..| .  ..|.||  |.. | |. ||||  ||| .. | ... .  .| || . ||  |.     |    .|| ..||.|
GCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYN

PKKRLTAEQALQSPFF
||.|.||..||. |.|
PKNRITASDALKHPWF

Kinase DDB0229294.AA CDK5 64-343 34 1.5e-72 228.44 In-house 1-287 (287) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-287/287
Sequence Identity: 34% (100 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFKGWTE--GDRASK-EECSLLQQLRHIPYITPVID-IYTNFETSEYIIVFPYFEHDLSGLLSEHR--LS
|| . |||||  | |.||  | |.|.||||  .   |  |  ..   | .||. |.| . |   .| | ..      ..|| .   ||   . .    ..
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKH-KNIVRLHDVIHSE---KKLTLVFEFCDQDLKKYMDSCNGEMD

IPQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGDLGTATSY-TKRSVFSSKVVTLWYRAPELLLGSTQYGPEIDMWSIGCVLIELV-TS
 . .| .  ||| |.   |.  |.||| |  |||.| .| |  .| | |  .      .|. |||||||.|  |.|| .|   |||||.||.. |.. . 
MHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAG

RNFLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFN-QISHLPVYPSRL--RTVFKNFSNDFIELLEGLLTLNPKKRLTAEQALQSPFF
|   ||.... ||  | |. |||. . || ...| ... ..  .|.|| .     . .. .    .||...| .||..|..|..||. |.|
RPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF

Kinase DDB0229294.AA CDK-Unclassified 64-343 27 4.1e-68 223.12 In-house 1-324 (324) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-324/324
Sequence Identity: 27% (89 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALK-----NFKG--------WTEGDRASKEECSLLQQLRHIPYITPVIDIYTNFETSEYI-------------
|... |.|||  |.|.|||.  |   || |     | ||          .     . | |.||.. | . |   .|..     .  .             
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIK-FMDMH--YDHDRCSKNPYYDNLHPSFY

IVFPYFEHDLSGLLSEHRLSIP--QVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKG-----SLFIGDLGTATSYT----------KRS---VFSS
.| .|   .... |   | .    |.. ...|.||||. .| .. |||||| .|... |..      | |.| | |  |            .     .|.
MVMEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYST

KVVTLWYRAPELLLGSTQYGPEIDMWSIGCVLIELVTSRNFLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVYPSR---LRTVFKNFSN
 |.| ||||||||.|| .|....|.||.||.. |..     ..| .|  |.  | |. |||... ||. ...   . |   .  . .   . . .|  |.
QVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPDYCKIFFKYKQKFHWWNRFPKCKHASE

DFIELLEGLLTLNPKKRLTAEQALQSPFF
 ..|..  .. ..|..|......||.| |
NNCEFQ--MVMYQPYNRWKCMEILQHPWF

Kinase DDB0229294.AA CDK10 64-343 36 1e-58 201.39 In-house 1-285 (285) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-285/285
Sequence Identity: 36% (104 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFKGWTEGDR---ASKEECSLLQQLRHIPYITPVIDIYTNFETSEYIIVFPYFEHDLSGLLSE--HRLSI
.| . ..|||  | |..|    ..|.||||  .   | |    ..  |  || |.|| . |  . ..    .     .|  | | ||  ||    .  . 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRH-ENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTE

PQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGDLGTATSYTK-RSVFSSKVVTLWYRAPELLLGSTQYGPEIDMWSIGCVLIELVTSRN
 ||||   |.| |.  .|.  ..|||.| .|||.  || . . | | |  |         |.|||||||||||||...    |||| .||.| ||.  . 
TQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKP

FLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVYPSRLRTVFKNFSNDFIELLEGLLTLNPKKRLTAEQALQSPFF
 .||.|| .|.. | .| ||| ..|||  |.|   .. .        |.  |.  |.   .||. |.  ||||| |||..|.| .|
LMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF

Kinase DDB0229294.AA CRK7 64-96 57 1.1e-09 29.36 In-house 1-33 (343) Show / Hide
Range on Protein: 64-96
Range on HMM: 1-33/343
Sequence Identity: 57% (19 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFK
||.|  ||||  | | ||  | |.|||||| ..
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVR

Kinase DDB0229294.AA CDK7 64-100 41 1.8e-09 20.92 In-house 1-39 (288) Show / Hide
Range on Protein: 64-100
Range on HMM: 1-39/288
Sequence Identity: 41% (16 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFK--GWTE
||.|..||||  . |.||  . |.. || |  |  | ..
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRS

Kinase DDB0229294.AA PITSLRE 64-96 42 8e-08 24.79 In-house 1-33 (295) Show / Hide
Range on Protein: 64-96
Range on HMM: 1-33/295
Sequence Identity: 42% (14 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFK
.... .|.||  | |..|  | |.| |||| .|
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLK

Kinase DDB0229294.AA TyrKc 64-343 18 8e-08 -96.13 SMART 1-280 (280) Show / Hide
Range on Protein: 64-343
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)

YEIISKIGEGISGSVFKAIKKGTEEMVALKNFKGWTEGDRASKEECSLLQQL--RHIPYITPVIDIYTNF-----ETSEYIIVFPYFEH-DLSGLLSEHR
 . . |.|||  | |.|.. |   ..|| |  |  .   ..  .| ... .|  .| | |   . . |       .   . ||. | .| ||   | .||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHH-PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LSIPQVKCYFKQLLEGINEIHNAGVMHRDIKAANLLVNNKGSLFIGDLGTATSYTKR-------SVFS------SK-VVTLWYRAPELLLGSTQYGPE
  |. ..   .  |  .| . .|  .. |||. | | ||....   |.| | .   .         .. .      .| .. .   ||| .     . ..
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTK

IDMWSIGCVLIELVTSRNFLPGSSEQQQLEAICKLCGTPTDEIWPNVSQLQNFNQISHLPVYPSRLRTVFKN-------FSNDFIELLEGLLTLNPKKRL
 | || | .. |. |                   ....|  ..  .     .  .. ..     |..    .        . .  .. .     .|..| 
SDVWSFGVCMWEIFT-------------------YGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP

TAEQALQSPFF
| ..     .|
TFSEI--HECF