Gene DDB0219953 (Slime mold)
DDB0219953
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
DDB0219953.AA | Protein | None | 605 | None | Fasta, JSON |
DDB0219953.kin_dom | Protein Kinase Domain | None | 286 | None | Fasta, JSON |
Protein domains of DDB0219953.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | DDB0219953.AA | CK2 | 312-597 | 67 | 4.8e-213 | 643.38 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-288/288 Sequence Identity: 67% (193 aa) YEVIQKIGRGKYSEVFSGIDIETSDEV--VIKVLKPVQKLKIQREIKILESLNGGPNIIPLLDSVKDQSSKVCSLVFPFVNKTDIRELVYTLDDYDIRYY ||||.|||||||||||.||.|...... |||.||||.| ||.|||||||.|||||||| |.|.|||..|||..|||..||.||.|.|..||.||||||| YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY IFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKRKLSLIDWGLAEYYHPGKNYNVRVASRHYKPPELLVNMFDYDYSLDMWSLGCLFAGLILDRDPFFNGD .||||||.||.||.||.|||.|| ||.|||.||||.||||||||.||||..||||||||.||.|||||.. .||||||||||||.||..|....|||.|. MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH NNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF .|.|||.||||||||.||...|||.|..|......... ..|..||||| .||...|.|.|||||||.||||..||.||||||.|||| DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF |
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Kinase | DDB0219953.AA | CMGC | 312-597 | 21 | 1.2e-100 | 331.53 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-513/513 Sequence Identity: 21% (109 aa) YEVIQKIGRGKYSEVFSGID--------------IETSDEVVIKVLKPVQKLKIQ---------------REIKILESLN----------------GGPN ||.|.|||.| |..|....| .|| .| || .| .. ..| ||||||. || .| YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN IIPLLDSVKDQSSK---------------VCSLVFPFVNKTDIRELVY-----------TLDDYD------------IRYYI------FELLKAID--YT |. |.|.... |. ||| .. .. . . |.. |.|.. . .|.... | IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC HSKG--IIHRDIKPLNIAIDHSKRK-------------------LSLIDWGLAEYYHPG----------------------KNYNVRVASRHYKPPELLV ||.. |||||.|| || |.| .. | ..|.||| .||| . | .|..|.|..||.|. HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL NMFDYD---------YSLDMWSLGCLFAGLILD-------RDPFFNGDNN-----------NDQLLKIVKVLG------------------TDDLFNFLD .. .|. .. ||||.|| || ... ..|.| |... ||| ||.|||| ... .|... GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK KFGLSLTDE----------QSSL----------IKPRQKSNWERFIPYEN-----------------DDIAQ-------------PDAIDFLDKLLRYDP . . .. . .|. ..... .|....| . .... |.|||.|.|.|.||| LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP TERLTAKEAMKHPYF ..|.||..|..|||| DKRITAEQALQHPYF |
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Kinase | DDB0219953.AA | Pkinase | 312-597 | 24 | 4.4e-74 | 257.22 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-293/293 Sequence Identity: 24% (77 aa) YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQKLKIQR-------EIKILESLNGGPNIIPLLDSVKDQSSKVCSLVFPFVNKT----DIRELVY- |....|||.| ...|. .... |...|..|..| . . . .. ||.|. .| . |||. |.|.. | .. . .|....... | ... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST ----TL--DDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKRK---LSLIDWGLAEY--YHPGKNYNVRVASRHYKPPELLVNMFDYDYSLDM .. .. ... |. ..|....| ||.||||||.|| || ||. . ..|.|||. | .. ..... ...| .||.. .|... || WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM WSLGCLFAGLILDRDPFFNG---DNNNDQLLKIVKVLGTDDLFNFLDK------FGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDKLLR ||.||... ... | || . || .||. .|....|.. |.. . | .. . | . .. . . ....||....|. WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------------F-HWTF-HNWSEECKDFIKWCLC YDPTERLTAKEAMKHPYF .||..|.||.....||.| KDPKKRPTAEQILQHPWF |
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Kinase | DDB0219953.AA | S_TKc | 312-597 | 25 | 2.1e-71 | 244.45 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-231/231 Sequence Identity: 25% (78 aa) YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQKLKIQREIKILESLNGGPNIIPLLDSVKDQSSKVCSLVFPFVNK--TDIRELVYT--------- ||...|||.| ...|. .....| .| ||..| .|.|||.||.. . |||. |.|. | . .|. ... | ... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP LDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKRKLSLIDWGLAEYYHPGKNYNVRVASRHYKPPELLVNMFDYDY-SLDMWSLGCLFAGLI .. ..|.|. ....|..| ||.||||||.|| || .|. . ..| ||| . . . ...| .||.| |.. . |.||.||... .. FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML LDRDPFFNGDNNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMK------ . | | |. .. |..| |.|.||..|.|..||..|.|| ||.. C-GYPPFP------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK -HPYF ||.| CHPWF |
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Kinase | DDB0219953.AA | CDK | 312-597 | 28 | 1.2e-61 | 195.98 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-284/284 Sequence Identity: 28% (93 aa) YEVIQKIGRGKYSEVFSGIDIETS-----DEVVIKVLKPVQ------KLKIQ----REIKILESLNGGPNIIPLLDSVKDQSS---------KVCSLVFP || ..|||.| | .|. ..| .| . | .| .. . | . |||..| | |||. |.| . . .. . ..||. YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE FVNKT-----DIRELVYTLDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKR----KLSLIDWGLAEYYH-------PGKNYNVRVASRHYK .. | |. |.. ||....| ||..|.|||.|| || |.. .| . | ||| .. | . | .| . | YMDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYR PPELLVNMFDYD--YSLDMWSLGCLFAGLILD--RDPFFNGDNNNDQLLKIVKVLGT--DDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDI .|||| .|. . ||||.|| || ...| | |.| ||. ||| || ...|| .| . |. . APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------- AQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF |.|.|.| |||. |..|..|..|||| ------DLLNKMLCYDPKKRISAEQALQHPYF |
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Kinase | DDB0219953.AA | CDC2 | 312-597 | 30 | 5.9e-48 | 145.17 | In-house | 1-301 (301) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-301/301 Sequence Identity: 30% (95 aa) YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQKLKI-------QREIKILESLNGGPNIIPLLDSVKDQSSKVCSLVFPFVNKTDIRELVY----- |. |.||| | | .|. ..| .| . |..| . | . ||| .| |. |||. | | .. . .|| ... | ... YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLD-MDLKKYMDMSIPK --TLDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKR-KLSLIDWGLA-EYYHPGKNYN--VRVASRHYKPPELLVNMFDYDYSLDMWSLGC .. .. |.. .|..... |...|.|||.|| || || . . |.. | ||| | ..| | . | .||.| .|. . ||||.|| NKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIA--DFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC LFAGLILD--RDPFFNGDNNNDQLLKIVKVLGT---------DDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDKLLRYDP .|| . .| . |.| || ||| || ..||| ..| . .|. . |.... .|| .. .. |..|| |...|.||| IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKK-------KNQ-SCLDPEGIDLLMQMLQYDP TERLTAKEAMKHPYF |..||||..|||| QKRISAKEALQHPYF |
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Kinase | DDB0219953.AA | CDK-Unclassified | 312-597 | 27 | 1e-44 | 144.92 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-324/324 Sequence Identity: 27% (91 aa) YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQ---------------KLKIQREIKILESLNGGPNIIPLLDSVKDQSSKVCS------------- |. ..|.|.| . .|. .|| .|. .| || . . |. ||||..| .| ||| ..| . | . || YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHM-NIIKFMDMHYDHDR--CSKNPYYDNLHPSFY LVFPFVNKTD---IRELVYTLDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSK----RKLSLIDWGLAEYYH-------------PGKNYNV .| . . | .| | .|| . .|. | | |...|.|||||| || |.. .| ..| |.| | |.. | . MVMEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYST RVASRHYKPPELLVNMFDYDYSLDMWSLGCLFAGLILDRDPFFNGDNNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIKPRQKSN-WERFIPYEN |. | |. |||| ||. |.||.|| .| .. . | | | . .|. .| |.||| . . | . .. | . . |. || . |.|| . QVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWF-QGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPD--WRYMPDYCKIFFKYKQKFHWWNRFPKCK- DDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF . .... .. |.| .|... |. .||.| ----HASENNCEFQMVMYQPYNRWKCMEILQHPWF |
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Kinase | DDB0219953.AA | Ciliate-E2 | 312-597 | 17 | 3.9e-42 | 142.41 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-365/365 Sequence Identity: 17% (73 aa) YEVIQKIGRGKYSEVFSGIDIETSD-----------------------EVVIKVLKPVQKLKIQREIKILE---------------SLNGGPNIIPLLDS |..|.|||.| .. |. . .... .. .|..|. |. | .||.|. ... |||| . .. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC VKDQSSKVCSLVFPFVNKTDIRELVY--------------TLDDYDIRYYIFELLK---------------AIDYTHSKG-IIHRDIKPLNIAIDHSKRK .... . . ||. ... | ... . .... |.|.. ..|. |. | |||. |||||||| || . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ LSLIDWGLAEYYHPG----------KNYNVRVA-----------------------SRHYKPPELLVNMFD--------YDYSLDMWSLGCLFAGLILDR . .||.||. .|.. |.| . .|..|| | . . |||. |.||||... .. . IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK DPFFNGDNNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQ-------------PDAIDFLDK----LLRYDPTER || .. .. ... . | ..| .| ....|.. | .| .|| .| PPF----------------------------------------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR LT-AKEAMKHPYF .| ......||.| ITGWEQILNHPWF |
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Kinase | DDB0219953.AA | CAMK | 317-494 | 17 | 1.8e-39 | 124.38 | In-house | 1-323 (425) | Show / Hide |
Range on Protein: 317-494 Range on HMM: 1-323/425 Sequence Identity: 17% (57 aa) KIGRGKYSEVFSGIDIETS------------DEVVIKVLK-------------------------------PVQKLKIQREIKILESLNG------GPNI ..||| ...|. .|...| .| ||... |. . ...|||.|. .|.| ||| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IPLLDSVKD-----------QSSK-------VCSLVF---PFVNKT----DIRELV------------------YTLDDYDIRYYIFELLKAIDYTHSKG | |.. | || . .|. .. |. . . .. . |.|. .. |..| ||.. IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN IIHRDIKPLNIAIDHSK----------------RKLSLIDWGLAEYYHP------------------------GKNYNVRVASRHYKP-PELLVN----- |.|||.|| || .|... .. .||.|.| .. | |. .. .. . .| . ||.| IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN --------MFDYDYSLDMWSLGCL |... ||||.|.. MQNATDEEKPYYGPKCDMWSCGVI |
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Kinase | DDB0219953.AA | MAPK | 465-597 | 37 | 8.5e-36 | 121.14 | In-house | 192-328 (328) | Show / Hide |
Range on Protein: 465-597 Range on HMM: 192-328/328 Sequence Identity: 37% (53 aa) VASRHYKPPELLVN--MFDYDYSLDMWSLGCLFAGLILDRDPFFNGDNNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIK------PRQKSNWER || | | ||.. | . .|. . ||||.|| || .. || |.| |.. ||. .|..|||| |. . . .. ..|. ...| .|| VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTP-SEEFIQCICM--SEHARNYIQSLGNLPKYPKKPWEK FIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF .| .| .|.|.|||.|.|.| || .|.|..||. |||| MFPNANF-NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF |
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Kinase | DDB0219953.AA | GSK | 467-597 | 28 | 2.4e-34 | 101.89 | In-house | 181-328 (328) | Show / Hide |
Range on Protein: 467-597 Range on HMM: 181-328/328 Sequence Identity: 28% (43 aa) SRHYKPPELLVNMFDYDYSLDMWSLGCLFAGLILDRDPFFNGDNNNDQLLKIVKVLGTDDL-----FNFLDKFGLSLTDEQSSLIKPRQKSNWER----- ||.| .|||. . .|. . |.||.|| .| ... . |.| ||. .||| |.|.|||.. .|. .. .... . .. .. | . SRYYRAPELIFGCTNYTCQIDVWSCGCVMAEMLK-GQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQT ----------FIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF .. . ..| . |.||.. |.|.|||..||.. ||..||.| YYHKKYRTVYMFKWCHTDMQ--DWIDLISKCLVYDPKKRLSPLEACAHPFF |
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Kinase | DDB0219953.AA | GSK | 312-444 | 26 | 4.1e-26 | 76.26 | In-house | 1-156 (328) | Show / Hide |
Range on Protein: 312-444 Range on HMM: 1-156/328 Sequence Identity: 26% (41 aa) YEVIQKIGRGKYSEVFSGIDI----ETSDE----VVIKVLKPVQKLKIQREIKILESLN--GGPNIIPLLDSVKDQ-SS-----KVCS-LVFPFVNKTDI || ...||.| . |. .... ||... |.|| . .. | .|| .|.. | |||. |. . . .. ..| ||. ....| YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY RELVY------TLDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKRKL ... . ......|..| . ..... | ||.|| |||||| || .|... .| QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVL |
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Kinase | DDB0219953.AA | MAPK | 312-438 | 30 | 1.3e-17 | 57.31 | In-house | 1-151 (328) | Show / Hide |
Range on Protein: 312-438 Range on HMM: 1-151/328 Sequence Identity: 30% (47 aa) YEVIQKIGRGKYSEVFSGIDIETSDE------VVIKVLK-PVQKLK----IQREIKILESLNGGPNIIPLLDSVKD-----QSS----KVCSLVFPFVNK |. ...|| | | |.| || .|.. |.|| . | |.. ..||||.| ... .||| ||| . |.| . .|... YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELME- TDIRELVY---TLDDYDIRYYIFELLKA--IDYTHSKGIIHRDIKPLNIAID || . . . .|.| |.| .. .|.. . | || ..||||.|| ||... TDLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN |
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Kinase | DDB0219953.AA | ERK | 549-597 | 42 | 7.4e-15 | 51.9 | In-house | 262-307 (307) | Show / Hide |
Range on Protein: 549-597 Range on HMM: 262-307/307 Sequence Identity: 42% (21 aa) RQKSNWERFIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF |.. .|| .| | . |.||| |.|.| ||..|.|..|. .|||| RPPKPWENIFPNAN---CNPQAIDLLEKMLVFDPDKRITVEECLEHPYF |
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Kinase | DDB0219953.AA | ERK | 465-524 | 36 | 1.3e-14 | 50.99 | In-house | 177-235 (307) | Show / Hide |
Range on Protein: 465-524 Range on HMM: 177-235/307 Sequence Identity: 36% (22 aa) VASRHYKPPELLVNMFDYDYSLDMWSLGCLFAGLILDRDPFFNGDNNNDQLLKIVKVLGT ||.| |..||.. . .|. . |.|| || ||... |.|.| | . .|. | ...|| VATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLG-RKPLFPGKDYVHQINRIFQIIGT |
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Kinase | DDB0219953.AA | CAMK | 556-597 | 22 | 1.8e-13 | 39.1 | In-house | 365-425 (425) | Show / Hide |
Range on Protein: 556-597 Range on HMM: 365-425/425 Sequence Identity: 22% (14 aa) RFIPYE------------NDDIAQP-------DAIDFLDKLLRYDPTERLTAKEAMKHPYF .|.|.. ||| . ...|.. |.|..||..|.|......|| . DFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | DDB0219953.AA | ERK | 312-372 | 38 | 6.1e-09 | 29.63 | In-house | 1-71 (307) | Show / Hide |
Range on Protein: 312-372 Range on HMM: 1-71/307 Sequence Identity: 38% (27 aa) YEVIQKIGRGKYSEVFSGIDIE-----TSDEVVIKVL-----KPVQKLKIQREIKILESLNGGPNIIPLLD |. |..||.| | |.| || | |.. | ||. .|. . ||||.| ..| .||| |.| YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFD |
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Kinase | DDB0219953.AA | TyrKc | 312-597 | 17 | 3.1e-08 | -89.45 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 312-597 Range on HMM: 1-280/280 Sequence Identity: 17% (56 aa) YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQKLKIQREIKILESL-NGGPNIIPLLDSVKDQ-----SSKVCSLVFPFVNKTDIRELV----YTL . ..|.|.| . ||. |. . .| .|.||. . . ||..|. .| |||. |. . .| ... .|. .. . | .. .| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL DDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSK-RKLSLIDWGLAEYYHPG-------KNYNVRV--ASR-----HYKPPELLVNMFD-YDYS | .. . . .| |||..||||. |. ... . | | | ||. . . . . | .. .. .|| . .. . CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKIS--DFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTTK LDMWSLGCL----FAGLILDRDP-FFNGDNNNDQLLKIVKVLGTDDLFNF----LDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDK | || | . | .. . .|..... || . . | .. .. . . SDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------F------VCCPDEMYQIMKQ LLRYDPTERLTAKEAMKHPYF ..|| .| | .| | .| CWHEDPEDRPTFSEI--HECF |
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Kinase | DDB0219953.AA | ERK | 406-435 | 43 | 0.001969 | 8.87 | In-house | 110-139 (307) | Show / Hide |
Range on Protein: 406-435 Range on HMM: 110-139/307 Sequence Identity: 43% (13 aa) IRYYIFELLKAIDYTHSKGIIHRDIKPLNI . | . .| .. | || ..||||.|| || CQYFMYQILCGLKYIHSANVIHRDLKPSNI |