Gene MARK-A (Slime mold)
MARK-A
Sequence
Protein domains of MARK-A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MARK-A.AA | MARK | 109-361 | 55 | 4.7e-166 | 546.61 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-262/262 Sequence Identity: 55% (145 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDP-ETLKMVQREVRIMKLLHHPNIIRLYEVIE--TSRA-LYLIMEYAGEGEVMDFMIAH--G | ..|||| | ..||||. ||. .||||||..| ||.. ...|.|.||..|||.|.|||||.|..||| |.. .|||||||..||..|...|| | YKMLKTIGHGSYAKVKLACHKHTG-RKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG VLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNR--QIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVL |.|. ||..|.|||||.||||||. ||||.||||.|.|.|. .|||||||.|. ..||. |.||||.| |..||..|.|.|.|| ||.||.||||... RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM VTGYLPFDGDN--YVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL |.||.|||||. |.||..|||.|.|.||... .||..||.|.|.|.|..|.|.||| .|||. VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MARK-A.AA | CAMKL | 109-361 | 45 | 3e-163 | 524.96 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-297/297 Sequence Identity: 45% (136 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIIN--KGKLDPETLKM-----------VQREVRIMKLLH---HPNIIRLYEVIETSRA------LYLIM | ..||.|.| ||||||. |.....||||||||. | ..|| ..|. ..||..|||.|. |||||.|||||||.. .||.| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYAGEGE--VMDFMIAH----GVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNR--QIKIIDFGLSNVFTP-----GSYLKTFCGSPTYA ||.. || .|. ..| | ..|..|| .|.|||||.|||||.. ||||.||||.|||.| .|||||||.|| ..| | |||||||| |. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM SPELILR--KEYNGPSVDVWSMGVVLFVLVTGYLPFDGDNYV---------ELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL .||.... |.|.|| ||.||.||.|...|.||||||.|.| .. .... ....|.... .|..||..||.|.|.||.|...| ||||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MARK-A.AA | AMPK | 109-361 | 54 | 1.2e-154 | 462.51 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-254/254 Sequence Identity: 54% (139 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKL-DPETLKMVQREVRIMKLLHHPNIIRLYEVI-ETSRALYLIMEYAGEGEVMDFMIAHGVLTE |.. ||||.| |||||.|.| .. .|||||||.|| |. | .. . .|||..|.||. ||.||.||||| || . ....|||. || |. . || |.| YIIGKTIGEGTFGKVKMGTH-ILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE SQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLP .|. || ||.|.. ||| |||||||||||||.| .||| ||||||. . | .||| |||| ||.||.| | |.|| ||.|| ||.|.... |||| REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP FDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL || .| .|..||..| |.||..|. |.|.||..|| ||| ||.| ..| ||||. FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | MARK-A.AA | CAMK | 114-361 | 32 | 1.8e-145 | 472.11 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 114-361
Range on HMM: 1-425/425
Sequence Identity: 32% (140 aa)
TIGRGQFGKVKLGYHKKIPN-----------EKVAIKIINKGKLD--------------------------PETLKMVQREVRIMKL-------LHHPNI
|.|||.||||||..||. .. .|||||||.| ||. |...|.|.||..|||. |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IRLYEVIE------------TSRA--------LYLIM---EYAGEG----EVMDFMIAH---------------GVLTESQARTFFTQIVSAINYCHSKR
|.||||.| | . .|..| ||. | .. |. ..| | .||..||..| ||.||..||||.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
AVHRDLKPENLLLDCN-----------------RQIKIIDFGLSNVFTP------------------------GSYLKTFCGSPTYAS-PELILR-----
|||||||||.||| | .|||||||..|.|.| | .|||||.| |.. ||....
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------KEYNGPSVDVWSMGVVLFVLVTGYLPFDGD-------------NYVELFQKILAGNYT-IPSYLTH-----------------------ECK
|.| ||..|.||.||.|.....||.||.|| |. |||.||..|.|. .|.|... |||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
SLISRMLVVDPDKRATMEEIINHPWL
.||..||.|||.||.| |.. ||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MARK-A.AA | NuaK | 109-361 | 46 | 3.3e-133 | 352.73 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-252/252 Sequence Identity: 46% (119 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKL-DPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTES | ..|| |.| .|||||.. .. .| |||| | | | |.. . . ||..|| |.||.|| ||| | . . ..|||| || |.. ..|.| YEFQKTLGKGTYGKVKLATEHSTGRE-VAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPER QARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLPF || || |||||. ||| | .||||| || ||| | .|| ||||||.. . |.|||||| ||||| . . |.|| || ||.||.|...| | .|| EARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPF DGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL ||... .| . | |.| | |. || || |.|..|||...| .|.|. DGHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV |
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| Kinase | MARK-A.AA | QIK | 109-361 | 48 | 8.9e-133 | 447.41 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 109-361
Range on HMM: 1-272/272
Sequence Identity: 48% (133 aa)
YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGV-----
| . .|||.| |. |||. | .| .||||||| | .|| | |. . ||| |||.| ||.||.||.|.|| ...|...||. .|| | ...||
YDIERTIGKGNFAVVKLARH-RITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM
---------------LTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSV
..|..|| |.||.||. |||.. |||||| ||.||| | |||.|||.|| |..| |.|.|||| || ||. . |||.|| |
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV
DVWSMGVVLFVLVTGYLPFDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
|.|||||||.|||.| |||||.. .| |..| | . || .. .| .|| .||||||..| |.. |..|.|.
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MARK-A.AA | S_TKc | 109-361 | 36 | 3.8e-110 | 373.15 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-231/231 Sequence Identity: 36% (99 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGE--GEVMDFMIAHGV--- | ....||.| ||||....||| ...||||||. ....||..|.| |||||..||.|... ||..|||.. |...|.. .| YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVL ..| .|| .. ||..|..||||.. .||||||||.||| .|||.||||. .. .||||.| | .||.. |.....|.|| |..|. . RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM VTGYLPFDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIIN-------HPWL ..|| ||. .. ..|.||. ..|.|..|...|..||.|| | |. . |||. LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MARK-A.AA | RAD53 | 109-361 | 35 | 2.1e-108 | 324.09 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-305/305 Sequence Identity: 35% (108 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGK------LDPETLKMVQREVRIMKLLHHPNIIRLYEVIET-SRALYLIMEYAGEGEVMDFMIAH |...|..|.| ||.|||.| || .|||||||.| | .. . . |..||.|.| |.||.|||.|....| .. .|...|... || ... ... YYMSKELGSGNFGTVKLAYEKK-TCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSN GV----LTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNR------------------QIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELIL . ..|......| |.. |..| |.. .|||||||| |.. .. .||| ||||| . ||..||.||.|.| || |. KRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVIT RK---------------EYNGPSVDVWSMGVVLFVLVTGYLPFDGD-----NYVELFQKILA-GNYTI----PSYLTHECKSLISRMLVVDPDKRATMEE | .| ...||.||||..|... .||.||. | . ||..|. |.| . . | |.||..||.|||.|| | .| SKGHNCYHENEERQVQVGY-TKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDE IINHPWL ..||||. ALNHPWM |
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| Kinase | MARK-A.AA | BRSK | 109-361 | 47 | 1.8e-106 | 360.05 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-254/254 Sequence Identity: 47% (122 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLD--PETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTE | . || |.|| |.|||| | .. .||||||||| || . |. | ||. |||| ||.....|.| |... ||||.|. || |... | || YRLEKTLGKGQTGLVKLGVH-CVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTP SQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLP || || ||.||...|||. |||||||||||| ..||| |||. . .. | | |||| ||.|| | .| | |||| ||.|. | .| || KEARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALP FDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL || || .| |. | . .| . | .| |. |||||| ...|| ||| FDDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY |
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| Kinase | MARK-A.AA | Pkinase | 109-361 | 34 | 6.2e-104 | 356.39 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-293/293 Sequence Identity: 34% (101 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQR--EVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEG----EVMDFMI--A | ....||.| ||.|....||. . .||.|||.| . ... .. | |..||| |.||||.|||.. |... .|..|||.. | . .|.. . YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR HGVL--TESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQI----KIIDFGLSNV--FTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWS ||.. .| ... ...||.....||||.. .||||||||.|.| | .| ||.||||. . ..| ..||||.| |..||.|. .| ||.||.|| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS MGVVLFVLVTGYLPFDGD------NYVELFQKILAGNYTIPSYLT---------------------HECKSLISRMLVVDPDKRATMEEIINHPWL .|..|. ...|..||.|. . .....|. . . ... . |||..|...| .|| || | |.| .|||. CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MARK-A.AA | SNRK | 109-361 | 47 | 5.6e-99 | 324.76 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-254/254 Sequence Identity: 47% (120 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGV-LTES | . ||.||| | ||| | ||||.|.| | |.| . . .||| ||| ||||.||||||.| ||||.| ... |... | | |. YDLEKTLGRGHFAVVKLARH-VFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCED QARTFFTQIVSAINYCHSKRAVHRDLKPENLL-LDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLP ||..| ||. ||.||| .. ||||||||| . . .|. ||| || | || |.|.||| |. ||..| .| | ||.||.||.|..|| | .| LARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAP FDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL |. | | .|. ||.|. . .||. || .||| || |||..||| .|.|. FQEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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| Kinase | MARK-A.AA | TSSK | 109-361 | 37 | 2.1e-98 | 323.55 | In-house | 1-289 (289) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-289/289 Sequence Identity: 37% (108 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEK---------------VAIKIINKGKLDPE-TLKMVQREVRIMKL-LHHPNIIRLYEVIETSR-ALYLIMEYAG | | |.||.| ..||...|.|| .. ||||||.. | .. . | || ||. |.|||||..|| .||.. |..|||| YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE EGEVMDFMIAH------GVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGS------YLKTFCGSPTYASPELI | . ... .. | |.|.|||..| |.|||. ||||. |||||| ||.||| .. ||..||| ........ .|||||| ||.|| . HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL LRKEYNGPSVDVWSMGVVLFVLVTGYLPFDG--DNYVELFQKIL--AGNYTI--PSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL . ..|.. .|||||||.|...|.| .||| | . . . .... .. |||.||..|| .| .|....||..|.|. RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM |
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| Kinase | MARK-A.AA | TyrKc | 109-361 | 27 | 1.9e-30 | 108.36 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 109-361 Range on HMM: 1-280/280 Sequence Identity: 27% (81 aa) YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLL--HHPNIIRLYEVIETS-------RALYLIMEYAGEGEVMDFMI .|..|.|.||.| .| | ..||.| ..... ... || |||. | |||||.||| |. .. |...|||. | |. ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR AHGV-LTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPG-------SYLKTFC--GSPT-----YASPELILRKEYN .|. |. .. | .|| . .| |||. .|||| | |.. |...|| ||||| . . .| .. |. | .|| | .... KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT GPSVDVWSMGVVLF-VLVTGYLPFDG-----DNYVELFQKILAGNY-TIPSY--------LTHECKSLISRMLVVDPDKRATMEEIINHPWL . |||| ||... .. | | | . |..... .|.. .| . . | ..... ||..| |..|| | . -TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | MARK-A.AA | Pkinase_Tyr | 109-254 | 34 | 1.7e-27 | 93.78 | Pfam | 1-158 (270) | Show / Hide |
Range on Protein: 109-254 Range on HMM: 1-158/270 Sequence Identity: 34% (55 aa) YLVIKTIGRGQFGKVKLGYHK---KIPNEKVAIKIINKGKLDPET--LKMVQREVRIMKLL-HHPNIIRLYEVIE-TSRA--LYLIMEYAGEGEVMDFMI .|..|.|.||.|..|. | . .. .||.|.. | . ..| ... ||..||| | |||||.||| |. .. .|..|||. | |. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR AH----GVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLS .| . || .. . .|| .. .| .||. .|||| | |...|...|| ||||. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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| UBA_CAMKL | MARK-A.AA | UBA_CAMKL | 490-527 | 48 | 1.1e-15 | 54.33 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 490-527 Range on HMM: 1-41/41 Sequence Identity: 48% (20 aa) DQEIIEELVGL--GFEREELCNSIRQNKY-NDAASTYFLLQ |.|||.|.. . || |||...|.|.||| |.. ||.||. DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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| UBA | MARK-A.AA | UBA | 490-527 | 28 | 5.8e-08 | 33.71 | SMART | 1-38 (38) | Show / Hide |
Range on Protein: 490-527 Range on HMM: 1-38/38 Sequence Identity: 28% (11 aa) DQEIIEELVGLGFEREELCNSIRQNKYNDAASTYFLLQ ..|.|..|...|| |||. . |....|. . ...|.. YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS |
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| UBA | MARK-A.AA | UBA | 489-525 | 21 | 0.000612 | 18.09 | Pfam | 1-38 (38) | Show / Hide |
Range on Protein: 489-525 Range on HMM: 1-38/38 Sequence Identity: 21% (8 aa) LDQEIIEELVGL-GFEREELCNSIRQNKYNDAASTYFL |.|....|. . ||.... |....| .. ...| IDEEMVKQLMEMTGFSMMQCKKALRACNNNVERAVEWL |
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| KA1 | MARK-A.AA | KA1 | 1011-1057 | 43 | 8e-24 | 83.08 | Pfam | 1-48 (48) | Show / Hide |
Range on Protein: 1011-1057 Range on HMM: 1-48/48 Sequence Identity: 43% (21 aa) ETEGVRFSIEICRLP-RLSVNGLKFKRIGGSSWRYKSICKDLLSQMKL |.| |.| |..|..| ||...|..|||..|..| ||..|...|..|.| EPEVVKFEIQVCKVPGRLGLYGVDFKRVSGNQWQYKDLCTKILKEMRL |
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