Gene FHAK2 (Slime mold)

FHAK2

Species: Slime mold
Alias: DdisK039, DDB0206066c, FHAK2
External Links: DictyBase Link ,
Annotation:

Classification

Group: CAMK
Family: RAD53

Sequence

Name Sequence Type Origin Length Description Download
FHAK2.AA Protein None 1142 None Fasta, JSON
FHAK2.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of FHAK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FHA FHAK2.AA FHA 480-568 22 5.9e-15 60.69 Pfam 1-73 (73) Show / Hide 
Range on Protein: 480-568
Range on HMM: 1-73/73
Sequence Identity: 22% (22 aa)

IVVGRSSSCDARLI-DNYLT-ISGKHCEI-YRADNLTCLKHIPLCKDKTDCHKNFGMLIVHD--ISSNGSYI--NGELIGNGKTRILRSDDILSLG
...||...|| .|  |   . .|..|||| .. ..                      ....|  .|.|| ..  ||. |..|....|.. |....|
WTIGRDPDCDIVLDND--PSFVSRHHCEIRRYDNG---------------------RWYIRDLGCSTNGTFVTGNGQRIQPGEPHRLHHGDRIRFG
FHA FHAK2.AA FHA 479-551 23 3.4e-09 37.8 SMART 1-49 (49) Show / Hide 
Range on Protein: 479-551
Range on HMM: 1-49/49
Sequence Identity: 23% (18 aa)

RIVVGRSSSCDARLIDNYLTISGKHCEIYRADNLTCLKHIPLCKDKTDCHKNFGMLIVHDIS---SNGSYINGELI
....||.| || .| ..   || .||.|.  |.                        ..| .   .|| |.||. .
TWTIGRHS-CDIQLPHPS--ISRHHCQIR--DGD----------------------YIIDLGEHSTNGTYVNGRRV
Kinase FHAK2.AA RAD53 625-885 40 1.4e-178 537.02 In-house 1-305 (305) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-305/305
Sequence Identity: 40% (122 aa)

YYFVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLK-N---GSTSKSMELVSKEYNALKNIKHRNVIEFFDIVFS-STDCFFIVELATN-DLSNLL--RK
||..||.|||..|.|.....| ....||||.||. | .   ..|.|.|. |..|...||...|...|...||... ........||.|. .|.| .  .|
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

RC---VDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGF---------------SIKITDFGLSSFVEESQYLQTFCGTPLFFAPEVIA-
||   .|||..|....|......|||..||.||||||||||.|.....                .|||||||||.||.|.....|.||||...|||||. 
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

---NNFFSN-------GYGKSCDLWSIGVTLYLSLCKYKPFIVD------CRDLYHSFIN-GNLGFTSKKWAKISNYAKDLVRRLLVIDPEHRITIKEAL
   |....|       ||.|..|.||.|..||..||.|.||..|      |..|.....| |...|....|..||..||||....|..|||.|.||.|||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

NHPWF
||||.
NHPWM
Kinase FHAK2.AA CAMK 630-885 22 5.4e-99 319.63 In-house 1-425 (425) Show / Hide 
Range on Protein: 630-885
Range on HMM: 1-425/425
Sequence Identity: 22% (96 aa)

EIGSGGYGIVYEGLYKLNG------------KRVAIKH-------------------IDLLKNGS-----TSKSMELVSKEYNALKN-------IKHRNV
..|.|..|.|...  |...            ..||||                    ||  |...     . |... | .|.. .|.       ..|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IEFFD-------------------IVFSSTDCFFIV----ELATND------LSNLLRKRC---------------VDEDDIKRICKQLLLGFNYLHNLG
| ...                   .. ........|    |....       .. . ...|               ..|.. .|. .|.. . .|.|...
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPENILYNEFKQG--------------FSIKITDFGLSSFVEE------------------------SQYLQTFCGTPLFFA-PEVIAN----N
||||||||||||... . .              . |||.|||.. ....                         | ..|||||| . | |||.      |
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

FF------SNGYGKSCDLWSIGVTLYLSLCKYKPFIVDC--------------RDLYHSFINGNLGFTSKK------------WAKISNY--------AK
..        .||..|| ||.|| ||  || | ||  ||              ..|..  ..|.  | ...            | .||.         .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLVRRLLVIDPEHRITIKEALNHPWF
||.|..|. |||.|.||...|||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase FHAK2.AA S_TKc 625-885 33 1.1e-87 298.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-231/231
Sequence Identity: 33% (94 aa)

YYFVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLKNGSTSKSMELVSKEYNALKNIKHRNVIEFFDIVFSSTDCFFIVELATN---DLSNLLRKRC---
| ....||.|..| || .  |  |..|||| |.           | . .| . ||. .| |.. ..|.  . .. ... |.. .   ||  ...||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----VDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGFSIKITDFGLSSFVEESQYLQTFCGTPLFFAPEVIANNFFSNGYGK-SCDLWS
     .| .......|.... .|.|..||.|||||||||| .|      |||.||||. ..       |||||| . ||||.       |||| .|| ||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL-------GYGKCKCDWWS

IGVTLYLSLCKYKPFIVDCRDLYHSFINGNLGFTSKKWAKISNYAKDLVRRLLVIDPEHRITIKEALN-------HPWF
.|..||  || | ||  .   ...                 |  |||..|..|. |||.|.|. |||.       ||||
CGCILYEMLCGYPPFP-QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FHAK2.AA Ciliate-E2a 625-885 34 2.2e-75 221.33 In-house 1-275 (275) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-275/275
Sequence Identity: 34% (96 aa)

YYFVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLKNGSTSKSMELVSKEYNALKNIKHRNVIEFFDIVFSSTDCFFIVELAT-NDLSNLLRKRC-VDED
| |.|.||.| .| ||    | .||. |.| ..  |.  . |  | . .| | .....| |.| ....  . .  ... |.    .| . ...    .| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--DIKRICKQLL-LGFNYLHNLGIVHRDLKPENILYN-EFKQG---FSIKITDFGLSSFV--EESQYLQTFCGTPLFFAPEVIANNF--FSNGYGKSCDL
  .|..| .|||  |..|.|...|.||||||||||..   |..   . ||| ||||. |.   | .|. . |||| . ||||..|    ... |...||.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSIGVTLYLSLCKYKPFIV-DCRDLYHSFINGNLGFTSKK-WAKISNYAKDLVRRLLVIDPEHRITIKEALNHPWF
||.|| .|. || . ||   . ..   .  . .. | ..  | |.|. .|||....|. ||..|||...|||||||
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase FHAK2.AA Ciliate-E2 625-885 24 5.3e-75 255.49 In-house 1-365 (365) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YYFVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLK-----------------NGSTSKSMELVSKEYNALKNIK----------------HRNVIEFFD
| |.| ||.|..|.||..  ....|..||| ||  |                 .    .  | ...| . .. |.                | |.|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

IVF--SSTDCFFIVELATN-DLSNLLRKR------------CVDEDDIKRICKQLLL---------------GFNYLHNLG-IVHRDLKPENILYNEFKQ
     . . .... |..   ||  .....            . .|  ||.| ||.|                ...|||. . |.|||.||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

GFSIKITDFGLSSFVEES--------------------------------QYLQTFCGTPLFFAPEVIANNFF-----SNGYGKSCDLWSIGVTLYLSLC
   |||.||||| .. ..                                .  .|.|||| . |||.. .        ..||...||.||.||.||  |.
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

KYKPFIVDCRDLYHSFINGNLGFTSK--------------KWAKISNYAKDLVRR----LLVIDPEHRIT-IKEALNHPWF
.. ||       .   ..... | ..              .| |.|. .||| ..    .|. ||| ||| ....||||||
GKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase FHAK2.AA CAMKL 625-885 28 2.2e-74 236.76 In-house 1-297 (297) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-297/297
Sequence Identity: 28% (87 aa)

YYFVKEIGSGGYGIVYEGLY-KLNGKRVAIKHIDLLKNGSTSKSMEL-----------VSKEYNALKNIK---HRNVIEFFDIV-------FSSTDCFFI
| ..|..| |..| |  ..  ...|..|||| ||  |     ...             . .|.. .| ..   | |.| .....        . .... .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

VELATND---LSNLLRKR-C----VDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFK-QGFSIKITDFGLSSFVEE-----SQYLQTFCGTP
 |.. .    | . ..|. .     .|.. .|. .|.. . ||.|..||||||.||||||  | . .   |||.|||.| . ..      | | ||||.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

LFFAPEVIAN--NFFSNGYGKSCDLWSIGVTLYLSLCKYKPFIVDCR------DLYHSFINGNLGFTSK-KWAKISNYAKDLVRRLLVIDPEHRITIKEA
 . |||...     .   .|.  | ||.||.||  .| | ||  |.       .    .   . | .   .| ..|  ..|| |..|. .||.|.||.. 
PYMAPEIFQGNNKPY---DGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI

LNHPWF
.||||.
MNHPWM
Kinase FHAK2.AA Pkinase 625-885 30 2.1e-73 254.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

YYFVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLKNGSTSKSMELVS-KEYNALKNIKHRNVIEFFDIVFSSTDCFFIVELATN-----DLSNLLR---
| ... ||||..| ||..  | .||.||.| |.. .. | .| ....   |   .|...| |.....|.. ..... .. |.. .     ||. ...   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKS-WKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KRCV--DEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGFS---IKITDFGLSSF--VEESQYLQTFCGTPLFFAPEVIANNFFSNGYGKS
..|.  .|...|....|.| | .|.|. ||.||||||||||..  ..|     .||.||||. .     .. ..|||||| . |||||    ....||..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPK

CDLWSIGVTLYLSLCKYKPFIVDC------RDLYHSFINGN--LGFTSKKWAKIS-----------------NYAKDLVRRLLVIDPEHRITIKEALNHP
.| ||.|..||  ||.. ||  ..      ....  . ..   | | . .|  ||                   .||.....|  ||. |.|....|.||
VDMWSCGCILYEMLCGRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WF
||
WF
Kinase FHAK2.AA CAMK-Unique 625-885 24 4.5e-72 237.16 In-house 1-363 (363) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-363/363
Sequence Identity: 24% (89 aa)

YYFVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLKNGSTSKSMEL------------------VSKEYNALKNIKHRNVIEFFDI----VFSST-----
| ... ||.|..|.|||.. . .||  |.|..   | .  .|.. .                    .| . .|  .| | |...|.    .  ..     
YKMHRIIGHGNFGHVYECMDRETGKKWACKMV--KKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCD

----------DCFFIVELAT-NDLSNLLRK--------------------RCVDED---DIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQ---
          ... . |... .||. .. |                    .....    |. .|. .||   .|.|...|||||||.|||....  .   
LIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN

----------GFSIKITDFGLSSFVEESQYLQ---TFCGTPLFFAP--------------EVIANNFFSNGYGKSC----DLWSIGVTLYLSLCKYKPFI
             ||..||||.  .....      |.||||.. ||              |||..     .|.  |    |.||.||..|. || . || 
HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINM----QCYDQQCSPASDIWSLGVIMYYMLCGCPPFD

VDCRD---------LYHSFINGNL-GFTSKKWAK---ISNYAKDLVRRLLVIDPEHRITIKEALNHPWF
 .| |         .. ..  |..  | .|.|     ||. |||.| .....|| ||...||.| |.|.
CECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase FHAK2.AA CAMK1 721-885 42 1.3e-71 207.42 In-house 107-276 (276) Show / Hide 
Range on Protein: 721-885
Range on HMM: 107-276/276
Sequence Identity: 42% (72 aa)

EDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGFSIK--ITDFGLSSFVEESQ-YLQTFCGTPLFFAPEVIANNFFSNGYGKSCDLWSIGVT
|.|  .| ||.|   .|.| .|||||||||||.||   . .. ||  | ||||| ....   ...| |||| . ||||...     .|.|.||.||||| 
EKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKACDMWSIGVI

LYLSLCKYKPFIVDC--RDLYHSFINGNLGFTSKKWAKISNY-AKDLVRRLLVIDPEHRITIKEALNHPWF
.|  || | ||  .     |.   ... ..| |. | .||.  |||... .|. ||. |.|....|||||.
TYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase FHAK2.AA ULK 625-885 27 6.8e-69 235.2 In-house 1-329 (329) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-329/329
Sequence Identity: 27% (89 aa)

YYFVKEIGSGGYGIVYEGL-YKLN---GKRVAIKHIDLLKNGSTSKS------MELVSKEYNALKNIK--------HRNVIEFFDIVFSSTD--CFFIVE
|.  ...|.| .| ||.|   | .   .. ||.| ||. |    ..       ..|. .|   .| .|        | |.....|.  .|..  ...|.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LATN-DLSNLLRKR-----------CVDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGF---------SIKITDFGLSSFVEES----Q
.    ||.... |.              |. .. ..||.| || .||  .|.|||.||.||| .. ....          .||.|||.. .|...    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

YLQTFC------GTPLFFAPEVIANNFFSNGYG-KSCDLWSIGVTLYLSLCKYKPFIVDCRDLYHSFINGNLG----------FTSKKWAK------ISN
 ..|.       ||||. ||... ..     |. . ||.||.|. .|  |  . ||    .|.|. .|. ..            .  .. |      ||.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

YAKDLVRRLLVIDPEHRITIKEALNHPWF
  ||| ||.|..|.. ||.. | .|||||
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase FHAK2.AA ULK 625-885 28 3.7e-67 229.43 In-house 1-324 (324) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-324/324
Sequence Identity: 28% (93 aa)

YYFVKEIGSGGYG-IVYEGL-YKLN--GKRVAIKHID---LLKNGSTSK---SMELVSKEYNALKNIK---HRN--VIEFFDIVFSSTD--CFFIVELAT
|.  ...|.| .|  ||.|   | |  .. ||.| ||   . |. . .     ..|  .| . .| .|   | |  .....|.  .|..  ...|.|.  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

N-DLSNLLRKR----------CVDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGF---------SIKITDFGLSSFVEES----QYLQT
  ||.... |.             |. .. ..||.. || .||. .|.|||.||.||| .. ....          .||.|||.. .|..     | .||
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FC------GTPLFFAPEVIANNFFSNGYG-KSCDLWSIGVTLYLSLCKYKPFIVDCRDLYH---SFIN-----------GNLGFTSK-KWAKISNYAKDL
..      ||||. ||... ..     |. . ||.||.|. .|  |  . ||  . .|.|.   . ||            .. | .. |  |||.  |||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VRRLLVIDPEHRITIKEALNHPWF
 ||.|..|.. ||.. | .|||||
IRRMLQYDEKDRISWEEIFNHPWF
Kinase FHAK2.AA Ciliate-E2-Unclassified 625-885 25 2.5e-65 223.35 In-house 1-352 (352) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-352/352
Sequence Identity: 25% (92 aa)

YYFVKEIGSGGYGIVYEGLYKLNGKRV-----AIKHIDLLKNGSTSKSMELVSK--EYNALK----------------NIKHRNVIEFFDIVFSSTDCFF
| ..| ||.||.|.||.   | ..  .     ..|...  ..   .|  |.. .  | | .|                |..| ... .|..  .   ...
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IVELATN-DLSNLLRK------------------RCVDEDDIK-----RICKQLLLGFNYLHNLG-IVHRDLKPENILYNEFKQGFSIKITDFGLSSFVE
. |.. . ||.. ..|                  ....|  .|     ....|.|.|..|||  . |.|||.||||||... .. . |||.|||.|.. .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

E----------------SQYLQTFCGTPLFF----APEVIANNFFSNGYGKSCDLWSIGVTLYLSLCKYKPFI-VDCRD----------------LYHSF
.                .| ..|||||| .     ||||. ..  ..   ..|| || || ||  |  | ||   .| .                ||  .
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

INGNLGFTSKKW----AKISNYAKDLVR----RLLVIDPEHRITIKEALNHPWF
...|. | . .|     ..|. |||...    ..|. .|. |||....||||||
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase FHAK2.AA Pkinase_Tyr 625-783 24 4.1e-17 58.57 Pfam 1-171 (270) Show / Hide 
Range on Protein: 625-783
Range on HMM: 1-171/270
Sequence Identity: 24% (44 aa)

YYFVKEIGSGGYGIVYEGLYK----LNGKRVAIKHIDLLKNGSTSK---SMELVSKEYNALKNI-KHRNVIEFFDIVF-SSTD--CFFIVELATN-DLSN
  | |..|.| .| ||.| .|     ..  ||.| .   |.|....   . .. . | . .|.. .| |.. .  ..   .     . ..|.. . || .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML---KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

LLRKR-----CVDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGFSIKITDFGLSSFV-EESQY-LQT
 |||.      ..  |.  .| |   | .||.. ...||||   |.| .|   .. .||.||||.  . ....|  ..
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKR
Kinase FHAK2.AA TyrKc 625-885 21 6.1e-16 35.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 625-885
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

YYFVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLKNGSTSKSMELVSKEYNALKNI--KHRNVIEFFDIVFSS-------TDCFFIVELATN-DLSNLL
  . |..|.| .|.||.| .|     ||.|    ||...    .|   .| . ....  .| |.. .. .. ..          . ..|.. . || . |
ITLGKKLGEGAFGEVYKGTWK---IQVAVK---MLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

RKRC--VDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGFSIKITDFGLSSFVEES--------QYLQTF--CGT---PLF-FAPEVIAN
||.   .  .|   .| |   | .|||  ...||||   |.|..| .    .||.||||| ....          | ..   .|    |.   |||.|  
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

NFFSNGYGKSCDLWSIGVTLY--LSLCKYKPFI-----VDCRDLYHSFINGNLGFTSKK-----WAKISNYAKDLVRRLLVIDPEHRITIKEALNHPWF
  . . .    | || ||...  .....  .       .. .....   .|.     .          .    .. ..    ||| | | .|   |  |
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase FHAK2.AA CAMK1 625-692 36 5.2e-11 28.19 In-house 1-76 (276) Show / Hide 
Range on Protein: 625-692
Range on HMM: 1-76/276
Sequence Identity: 36% (28 aa)

YYFVKEIGSGGYGIVYEGLYKLN---GKRVAIKHIDLLKNGSTSKSM---ELVSKEYNALKN---IKHRNVIEFFDI
| | ||||.|  ..||..  | .   || .||| ||  |     |.|   |.. .| . .|.   |.| |.| |...
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK-KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEW