Gene VwkA (Slime mold)

VwkA

Species: Slime mold
Alias: VwkA, DdisK256, DDB0216405, vwkA
External Links: DictyBase Link ,
Annotation:

Classification

Group: Atypical
Family: Alpha
Subfamily: VWL

Sequence

Name Sequence Type Origin Length Description Download
VwkA.AA Protein None 625 None Fasta, JSON
VwkA.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of VwkA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Alpha_kinase VwkA.AA Alpha_kinase 391-592 30 6e-98 332.62 SMART 1-255 (255) Show / Hide 
Range on Protein: 391-592
Range on HMM: 1-255/255
Sequence Identity: 30% (79 aa)

SYEMKLNEITISIKIAPNPFSHGACRLAYLGID--------EHGKKVVLKQSKYIGGRENSKKRYFE--------SMECQTVAAKFALEFNKQLSLTSSE
.....  |....| ..|.||..||.|..| |.|         ||...|.|. |..  |. ...|||.        ..|.|... ..| |||...... ..
DNKWTCQETCVKI-KEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQHNPCP

HQITFTVAKVLQMK-------HSEKPMY----------------FGIETFINGEYQKYNSNCGWLKDDAMSEI-----------LQTFSHWTYQESKNKA
..|.|... |....       . ..|..                |..| |..||..|||.|.|| .|.....            .|.||||||..|.   
KKIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTTSQRRTEMFEYCQAFSHWTYEWSNHQM

IVVDIQGVKTSKGY--LLTDPAIHSTD--TLRFGSCNLGKPGIIKFFQSHKCNQHC
.|.|||||....|.  ..|||.||..|  .  ||..|||. || ||||.|.|||.|
LVCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Kinase VwkA.AA Alpha_kinase 410-592 30 2.2e-74 258.22 Pfam 1-225 (225) Show / Hide 
Range on Protein: 410-592
Range on HMM: 1-225/225
Sequence Identity: 30% (70 aa)

FSHGACRLAYLGIDE------HGKKVVLKQSKYIGGRENSK-------KRYFESMECQTVAAKFALEFNKQLS-LTSSEHQITFTVAK-VLQMKHSEK--
|..||.| .....|       .... |.|. |.|. ..|.|       . ||. ...|... ... .||..|.   . ...|.| ..  |.......|  
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIK-NYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHNKPD

-------------PMYFGIETFING-EYQKYNSNCGWL-----KDDAMSEILQTFSHWTYQESKNKAIVVDIQGVKTSKG--YLLTDPAIHSTDTLR---
             ..|. .|..|.| |..|||.|.||      ..| . ...|.|||.||..|  . .|.||||| . ..  |.||||.||..|  .   
CYQGFFSYRTDWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGY-NNKCYYLTDPQIHTKDGNYEMD

F--GSCNLGKPGIIKFFQ-SHKCNQHC
|  | .|||. || |||| .||||..|
FDEGMGNLGQEGIEKFFQNQHKCNHIC
Kinase VwkA.AA Alpha 399-592 30 2.3e-53 150.13 In-house 1-215 (215) Show / Hide 
Range on Protein: 399-592
Range on HMM: 1-215/215
Sequence Identity: 30% (69 aa)

ITISIKIAPNPFSHGACRLAYLGIDEH-GKKVVLKQSKYI--GGRENSKKRYFESMECQTVAAKFALEFNKQLSLTSSEHQI--TF------TVAKVLQM
.  .|...  ||. || | |.   | .  .| |.|| |..  .  . ..... . .| |.|.    .|||..|    .|. .  .|      ... .  .
QCTKIQMSSYPFMEGAMRYAMHAWDCWLHQKMVKKQHKKQWKSF-KYVWHHWIKDVERQMVCHHCVREFNQRL----WEQEYTTHFNQMKPQPIKQFVHC

-------KHSEKPMYFGIETFINGEYQKYNSNCGWLK----DDAMSEILQTFSHWTYQESKNKAIVVDIQ-GVKTSKG-YLLTDPAIHS---TDT-LRFG
       .|.  . |. .| .. |||||||.| || .    |.  ... |.|||||.| |.   .|||.| ||    |  .|||| ||.    |.  .||
YIYELIHCHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQWGV----GEWKLTDPQIHCPAKLDQGMKFG

SCNLGKPGIIKFFQSH--KCNQHC
  |.|. |. .|| .|  .|| .|
DGNCGYEGMFRFFYTHHVQCNHYC
Kinase VwkA.AA VWL 488-597 41 2.9e-42 123.82 In-house 96-206 (206) Show / Hide 
Range on Protein: 488-597
Range on HMM: 96-206/206
Sequence Identity: 41% (47 aa)

KHSEKPMYFG-IETFINGEYQKYNSNCGW--LKDDAMSEILQTFSHWTYQESKNKAIVVDIQGVKTSKGYLLTDPAIHSTDT-LRFGSCNLGKPGIIKFF
.| ......  .| .| |.||||| | ||  ..|.  . . | ||| |.| |.    .||.||.    | .|||| ||  |   .||  ||| .|. .||
HHYNHNIKYYFVENYIEGDYQKYNNNAGWCNQTDMEYNQLSQAFSHFTWQYSQGYCMIVDLQGNE--DG-MLTDPQIHCLDQSHKFGQGNLGYEGMLRFF

QSHKCNQHCKKLGL
 .|.||..|.|| |
MTHQCNKYCQKLQL
Kinase VwkA.AA Alpha-Unclassified 448-592 29 1.6e-27 86.7 In-house 59-215 (215) Show / Hide 
Range on Protein: 448-592
Range on HMM: 59-215/215
Sequence Identity: 29% (47 aa)

FESMECQTVAAKFALEFNKQLSLTSSEHQITFTVAKVLQMKHSEKPM-YFGIETFINGEYQKYNSNCG----WLK-DDAMSEILQTFSHWTYQESKNKAI
|   | |  |  .  |||| |       ||   .  .|  .       .  .|  . ||. ||..| |     .| ..   .  .|..||||| .  . |
FTDVERQMTAQHYVTEFNKRLYEQNIPTQIFYIPPIFLIHREDKNIKGCISVEPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDI

VVDIQG-VK--TSKGYLLTDPAIHSTDTLRFG--SCNLGKPGIIKFFQSH--KCNQHC
|.| || |    .|   .|||.||. .  |..    | |. .| ..|..|  .||. |
VCDLQGWVDENDKKTWKMTDPQIHTIRQ-RYQGFKTNCGMRFIDYWFNNHHVQCNHYC
Kinase VwkA.AA ChaK 495-592 37 3.1e-14 52.65 In-house 119-219 (219) Show / Hide 
Range on Protein: 495-592
Range on HMM: 119-219/219
Sequence Identity: 37% (39 aa)

YFGIETFINGEYQKYNSNCG--WLKDDAMSEILQTFSHWTYQESKNKAIVVDIQGVKTSKGYLLTDPAIHSTDTLR-----FGSCNLGKPGIIKFFQSHK
.| || .. ||. ||| | |   .    . ||.  ||||||   .   .|.|.|||    |  ||||..   .  .     ||  |||   |  |   | 
WFTIEKCMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGV----GENLTDPSVIKPEEKQSCDMVFGPANLGEDAIRNFRAKHH

CNQHC
||  |
CNSCC
Kinase VwkA.AA VWL 399-419 42 0.005956 4.74 In-house 1-21 (206) Show / Hide 
Range on Protein: 399-419
Range on HMM: 1-21/206
Sequence Identity: 42% (9 aa)

ITISIKIAPNPFSHGACRLAY
|  ...|   ||. || | ||
IKTKVRISNIPFAEGAMRYAY