Gene TAF1 (Slime mold)
TAF1
Sequence
Protein domains of TAF1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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TBP-binding | TAF1.AA | TBP-binding | 3-41 | 34 | 0.000314 | 16.89 | Pfam | 3-48 (77) | Show / Hide |
Range on Protein: 3-41 Range on HMM: 3-48/77 Sequence Identity: 34% (16 aa) KDKEKKG-----NLTGFLFGNVKESGELDVE-ENDQVF-KDLKKDL | .. . |||||||||. |.| |. . . .| . ...|. | DDNDNERNSRGFNLTGFLFGNIDEHGQLEDDDFREQGLDEECKEHL |
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DUF3591 | TAF1.AA | DUF3591 | 839-894 | 29 | 0.000335 | 15.97 | Pfam | 1-61 (494) | Show / Hide |
Range on Protein: 839-894 Range on HMM: 1-61/494 Sequence Identity: 29% (20 aa) FNL--SNDKFYRPVRKPPPRPPNGSTKV-------VIQHSLPGIKLSLV--KTHLTKEDLIYAHRPR ||. |||..| . .. | .|| |.||.| ..|.. |..|.|... |||. FNIIFSNDEYYDMLKE------NHQNKVRQTIGNLNIEHSMPALRLQWPYYKVKLNKREARSFHRPH |
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DUF3591 | TAF1.AA | DUF3591 | 967-1342 | 35 | 8.10000000001e-106 | 362.64 | Pfam | 108-494 (494) | Show / Hide |
Range on Protein: 967-1342 Range on HMM: 108-494/494 Sequence Identity: 35% (139 aa) SDLSARD-GRLVLIEYTEQHPPLVSNVGMGLRIRNYYKKKNTHDTGPKDLN-FEDGELVMLDNNEESPF--LGDINPGQTIQSVVNNLFKVPIHKHNSAN .||. .| . ..|.||.|..||. ||.||| .| |||.||. ||.. .| . || |. . .||| .| . ||.... ||.. .|| ||. .. KDLTLGDNSPVILMEYCEEYPPVMSNFGMGSKIINYYRKKHMEDTHRPKLDDI--GETHVLHPQDKSPFWNFGHVHPGEIVPTLYNNMYRAPIFKHKPEP TDFLLVKSRD----GKRWYIRDVGPIYAAGQILPEVEVPAPNSRNANMFLKSRLQAYIYRQFLKKSNPQRRLKITDICSAF-PSQSETSIRKRLKDCADF ||||...|.. | ..|.| . ....||..| .|||.|.|| .... | ||.. .|| | . .|..|..| || .| | |.| ..|.|||..... TDFLCIRSTTPGGHGQKYYLRNIDHMFCVGQTFPVMEVPGPHSRKVTNMSKNRLKMIVYRLFWGQKSPRHRISIHDITKHFFPDQNEMQNRQRLKEFMKY QRGG-DD-SGWWTVKDNFTLPTE-EEFQKLVTPEAVVSFESMLIGLQRLQDNGIIHFTAPGTIPTILGNLDDEDPIKKSIKPVEDELSITPWNLTGSFLS || | .| .||| |...|||.| || |..||| . . ||| |.|.|.|.|. . ...|||. || ....|.. .|||.| |. QRDGGMDNQGWWKLKEGETLPDEFEEIRKMITPEDCCLYESMQVGQQHLEDAGYNNTDEFKRDYQQIQEDDDEE-TKKVQMKIDLEQMMAPWNTTRNFIN AMQGKGRLQII-SDDPTGREDEYSYLKM-PQKVVNQKQKAIKLALQKNQVTGTDADLRKLSLSASKTVLLELGVDEETINKLARWQRIDL |.||| ||. ||||... .|... ..| .||. . . | .|.||.|..|.... . . || || |... .||...| ATQGKAMLQLHGEGDPTGCGEGFSFIRTKSMKGGFLKQGEGPQDKPKKAVAGTRAKERGGHSYNVAQQQRLYGVPEEEIRRIWYWQKRSL |
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Kinase | TAF1.AA | Bromodomain | 2121-2205 | 26 | 1.4e-19 | 66.15 | Pfam | 1-89 (89) | Show / Hide |
Range on Protein: 2121-2205 Range on HMM: 1-89/89 Sequence Identity: 26% (24 aa) FERILD--KLRTNDEFIAFRHKV--TPKLAPDYHKVIKNPIDLTTMRDRNRHWEYK-SKNQFIDAIKLMVANCFEYNE-KRFSHLLPIAEK ...|.| .. .... .|.| | .. |||...||.|.||.|.. . . .|. . .|. ..|| || .||. .. . .|.| CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYK--DARK |
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BROMO | TAF1.AA | BROMO | 1579-2219 | 5 | 4.8e-15 | 57.24 | SMART | 1-118 (118) | Show / Hide |
Range on Protein: 1579-2219 Range on HMM: 1-118/118 Sequence Identity: 5% (33 aa) DEETKKQRRRIQERLRRLKKNDQREDSFNMNSSNSSIGATIGSSNMINISAGNIPVSNINNNNYNNNNNNNNFSLNTSSSNKPIPPHRSSSSGIGSSGSN |.. .|. .. . ....|... . DPK-QKKCQELLKEVMCHKHDHGDPM-------------------------------------------------------------------------- NNSNTDRDQTRISIVMPNQQANSDSNSSSSTKIRIGQSSSSSSSSSSSSGHPRSSDREHRSSEHRSGEHRSSEHRSSEHRGSEHRSSEHRSGEHSSHHRS ---------------------------------------------------------------------------------------------------- SEHRSGDREHRSSDRGDREHRSSEHRSSEHRSSEHRSSEHRSGDKEHRSDREHRSSEHRSGDREHRSDREHREHRSGDREHRSDREHREHRSERSRNSSS ---------------------------------------------------------------------------------------------------- GSSSSSRDHRDSHHRNSTGSSSDSHSSSHHSSSNRDSNHNGGSSSNNNNNNSNNNHNNNNNSNNNNNNNNNNNNNNNINNNNNNNNNINNINNNNNNNIN ---------------------------------------------------------------------------------------------------- NINNNYNNNNNNNNNNNNNNNNNNNNNNINNNENNNTNNLSNSTNQSPTLSQSGIIIRYNGSNSGNSNNTNGGNNRTEDQSVLNTPLSASSSGSNRKKRT ---------------------------------------------------------------------------------------------------- LDQSNSESPSLSSTTLDGSDKSSRRNRVRKDGSGADVELSNIFERILDKLRTNDEFIAFRHKVTPKL--APDYHKVIKNPIDLTTMRDRNRHWEYKSKNQ | .. . |...|..|. .|||...||||.|| |.. . . ..|.| . -------------------------------------------------NRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEE FIDAIKLMVANCFEYNEKRFSHLLPIAEKLLTSTLQLLAPFDS |.| ..||. ||. ||| . |. |.|| ...... | FVDDFMLMFNNCMTYNE-PDSEVYKMAKKLQKFFEEKWREFPP |
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Kinase | TAF1.AA | Dicty3 | 1654-1972 | 12 | 6.5e-14 | 42.14 | In-house | 300-385 (351) | Show / Hide |
Range on Protein: 1654-1972 Range on HMM: 300-385/351 Sequence Identity: 12% (44 aa) NTSSSNKPIPPHRSSSSGIGSSGSNNNSNTDRDQTRISIVMPNQQANSDSNSSSSTKIRIGQSSSSSSSSSSSSGHPRSSDREHRSSEHRSGEHRSSEHR | N--------------------------------------------------------------------------------------------------- SSEHRGSEHRSSEHRSGEHSSHHRSSEHRSGDREHRSSDRGDREHRSSEHRSSEHRSSEHRSSEHRSGDKEHRSDREHRSSEHRSGDREHRSDREHREHR ---------------------------------------------------------------------------------------------------- SGDREHRSDREHREHRSERSRNSSSGSSSSSRDHRDSHHRNSTGSSSDSHSSSHHSSSNRDSNHNG------------------------GSSS------ | | |. ----------------------------------------------------------------NNKMSSTCRDIQCYYSNEINWKLIDFGLSKNISYYS NNNNNNSNNNHNNNNNSNNNNNNNNNNNNNNNINNNNNNNNNINNINNN |||||| .|| ||||| ||||||||||||||| |||||.||| ..|||| NNNNNNNYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNVKIINNN |
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Kinase | TAF1.AA | Dicty3 | 1973-2101 | 30 | 0.004459 | 5.78 | In-house | 193-251 (351) | Show / Hide |
Range on Protein: 1973-2101 Range on HMM: 193-251/351 Sequence Identity: 30% (39 aa) NNNNINNINNNYNNNNNNNNNNNNNNNNNNNNNNINNNENNNTNNLSNSTNQSPTLSQSGIIIRYNGSNSGNSNNTNGGNNRTEDQSVLNTPLSASSSGS |||| || ||| |||||||||||||||||||||| ||| ||| .. | NNNNNNNYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNVKIINNN--------------------------------------------------- NRKKRTLDQSNSESPSLSSTTLDGSDKSS . . ..|.. -------------------IYSNKQYKQK |