Gene Rio2 (Slime mold)
Rio2
Sequence
Protein domains of Rio2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | Rio2.AA | RIO2 | 71-306 | 51 | 1.3e-144 | 486.67 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 71-306 Range on HMM: 1-260/260 Sequence Identity: 51% (135 aa) YKLTYLGYDFLALKTLVSRGVCSYVGNQIGVGKESDIYIVANDDNQEMVLKLHRLGRVSFKTIKNNRDYLKHRKSASWLYLSRLAALKEFAYMKALYENG |.|| |||.|||||| || | ||||.|||||||||...| . . ...|.||||| ||..|||||||.||| ..||.|||||.| ||...|..||... YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN FPVPTPIDYNRHCIVMSRARGYPLTQIVQLRHPSKVYSDLMNLIVKLASYGLIHGDFNEFNILINDEEE------ITLIDFPQMVSTSHLNAEMYFDRDV |||| ||||||| .||. |||. || . | .||...| .||.|| ||||.||||||..| |. . ...|||||||||.| ||. |||||| FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRDV TCIRVFFEKRFNFIGERWP------------------KFKDCQNIHSLDVEISASGFTRD ||..||.||||. . | |.| | ||.|..||||. DCIHRFFMKRFNYEPKPFPSMLDTEGFGDGYKYAYPDFFRDIQRTDTLDEEVQASGFNKK |
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| Kinase | Rio2.AA | RIO | 71-299 | 35 | 4.1e-109 | 368.8 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 71-299 Range on HMM: 1-276/276 Sequence Identity: 35% (99 aa) YKLTYLGYDFLALKTLVSRGVCSYVGNQIGVGKESDIYIVANDDNQ-----------EMVLKLHRLGRVSFKTIKNNRD---YLKHRKS-ASWLYLSRLA |..| .|. ......|.||. |||.||||||||||...| . . | ..|.||.|| |||..|..|| |.||| . ..|.|..||. YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW ALKEFAYMKALYENGFPVPTPIDYNRHCIVMSRARG-------YPLTQIVQLRHPSKVYSDLMNLIVKLASYG-LIHGDFNEFNILINDEEE------IT | ||...||.||..|||.|.||||.|| .||. . ||. || . ...||...| ....|. . |.|.||||||... |. . .. AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY LIDFPQMVSTSHLNAEMYFDRDVTCIRVFFEKRFNFIGERWPKFKDCQ------------------NIHSLDVEIS .|||||||...| .|. ||.||. |...||.|||. . . . ..| .||.| . MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM |
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| Kinase | Rio2.AA | RIO1 | 106-285 | 28 | 7e-67 | 209.03 | Pfam | 1-200 (200) | Show / Hide |
Range on Protein: 106-285 Range on HMM: 1-200/200 Sequence Identity: 28% (58 aa) DIYIVAN-DDNQ-EMVLKLHRLGRVSFKTIKNNRDYLKH----RKSASWLYLSRLAALKEFAYMKALYENGFPVPTPIDYNRHCIVMS---RARGYPLTQ ..| .. |.. |...|..|.|. .|| .| ||| .. . .|.|..|..| |||...|..|| |.|.| |||.|||..||. ...|.|. . NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR IVQLR--------HPSKVYSDLMN--LIVKLASYGLIHGDFNEFNILINDEEEITLIDFPQMVSTSHLNAEMYFDRDVTCIRVFFEKRFNFI-GERWPKF . .. .. .| ... ...... ||.|||..|.|||. |......||.||.|...| .|.....||...| ||.... . . ... LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI |
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| RIO | Rio2.AA | RIO | 64-287 | 22 | 2.4e-52 | 181.11 | SMART | 1-253 (253) | Show / Hide |
Range on Protein: 64-287 Range on HMM: 1-253/253 Sequence Identity: 22% (57 aa) DGRNYDGYKLTYLGYDFLALKTLVSRGVCSYVG--NQIGVGKESDIYIV----ANDDNQEMVLKLHRLGRVSFKTIKNNRD-YLKHR---KSASWLYLSR | ..|..| ... ... ..|...| ||. . .. ..|..|||...| . . .. |.. | .|... .||....... . . . ..|....| DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR LAALKEFAYMKALYENGFPVPTPIDYNRHCIVMS--RARGYPLTQIVQLRHPS-------KVYSDLMNLIVKLASYG-LIHGDFNEFNILIN-----DEE |.| ||| .. .|| |.|.|.||...|| .||. ..|.| . . . ..|...| ..|.. . |.|.|..|.|.|. ... LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC EITLIDFPQMVSTSHLNAEMYFDRDVTCIRVFFEKRF--NF--IGERWPKFKD .. .||..| |...| .. .. ||...|. ||... .. | . .... KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG |
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| Rio2_N | Rio2.AA | Rio2_N | 8-89 | 55 | 2.2e-51 | 175.76 | Pfam | 1-84 (84) | Show / Hide |
Range on Protein: 8-89 Range on HMM: 1-84/84 Sequence Identity: 55% (47 aa) LRYLSKDDFRTLVAVEMGMKNHELVPVSLICTIANLK-YGGTKKSIQTLHKFKLLFH-DGRNYDGYKLTYLGYDFLALKTLVSR .|||||.|||.| ||||||.|||.||..||..|..|. ||...... |.|.||. | .. ||||.|||.|||.|||.|.|.| MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR |
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| Kinase | Rio2.AA | Ciliate-C3 | 217-245 | 48 | 4.3e-07 | 21.79 | In-house | 112-140 (140) | Show / Hide |
Range on Protein: 217-245 Range on HMM: 112-140/140 Sequence Identity: 48% (14 aa) LASYGLIHGDFNEFNILINDEEEITLIDF | . ..||| ||||| ..|| .||| LHEHNIVHGDIKFSNILINSKDEIKIIDF |
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| Kinase | Rio2.AA | APH | 95-219 | 13 | 0.000198 | 15.99 | Pfam | 1-112 (248) | Show / Hide |
Range on Protein: 95-219 Range on HMM: 1-112/248 Sequence Identity: 13% (18 aa) VGNQIGVGKESDIYIVANDDNQ-EMVLKLHRLGRVSFKTIKNNRDYLKHRKSASWLYLSRLAALKEFAYMKALYENGF--PVPTPID-------YNRHCI . .|. | ... | . .|| . ..||.. .... .. .. .|.. ...| ..|. ||| ... . .. WWRPISGGWSNRTYYRTTDD-RPRYVLRR-------------------YPPP-----WWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGWPWY VMSRARGYPLTQ-I-VQLRHPSKVYSDLMNLIVKLAS .|.. | .|.. . ... ... .| ....| . LMEWLPGEDLWRWHALHCAQRPALLEALARFLARLHQ |
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| Kinase | Rio2.AA | APH | 221-245 | 27 | 0.007422 | 10.62 | Pfam | 171-199 (248) | Show / Hide |
Range on Protein: 221-245 Range on HMM: 171-199/248 Sequence Identity: 27% (8 aa) GLIHGDFNEFNILIN---DEEEI-TLIDF ...||||. |.... |.... .||. CWCHGDFHPGNVMWDPRPDGGRVTGVIDW |
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