Gene DhkI (Slime mold)
DhkI
Sequence
Protein domains of DhkI.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| HisKA | DhkI.AA | HisKA | 549-613 | 31 | 8.3e-16 | 58.06 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 549-613 Range on HMM: 1-69/69 Sequence Identity: 31% (22 aa) LKGEFLANISHELLSPMNSIIGMVGLCLD---VAPRN-LKEMLNDVVESSKILLDLLHQILDFTTLESN |..||||.|||| |...|.|.. |..| | ..|.|. . .... ...|. ..|||. .|.. AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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| HisKA | DhkI.AA | HisKA | 549-613 | 23 | 1.4e-15 | 59.02 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 549-613 Range on HMM: 1-89/89 Sequence Identity: 23% (21 aa) LKGEFLANISHELLSPMNSIIGMVGLCLD------------VAPRNL------------KEMLNDVVESSKILLDLLHQILDFTTLESN |..||||.|||| |...|.|.. |..| | . .|.|. . .... ...|. ..||.. .|.. AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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| HATPase_c | DhkI.AA | HATPase_c | 660-907 | 17 | 1.6e-34 | 122.34 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 660-907
Range on HMM: 1-120/120
Sequence Identity: 17% (45 aa)
GDQNRLKQILSNLIDNAIKFSNSSNINNSISIIVEQLTHNQFKKYKDSFRSNSKTHSRLNSHDDYSIDGDYDDQDNNDSYFGRDINVSDNESAVGGFSEL
||..||.|...||.|||||.. .. |.. |..
GDPDRLHQVVWNLVDNAIKHTPEG---GHITVRVHRDD--------------------------------------------------------------
DEKDNSDDDDENDDENDETDENDDDTDDDTSSNTSRNNISNNLLFHNNTSGGGGGGINKREKFKKKDREGFVNLKFSIKDRGIGVPE------DKHDFIF
.. ....| |.|.|. .. . ||
-----------------------------------------------------------------------DHVRITVEDNGPGIPPEMHSIAEDIPRIF
DRFFQVDG-SYSRVQGG--VGLGLSICKKLIEFFGGAIWFESEASQGSTFHFILSIK
..|...|. | | || ||||.||....| .|| ||.||| .|.||.| | .
EPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE
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| HATPase_c | DhkI.AA | HATPase_c | 660-908 | 16 | 2.6e-33 | 117.91 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 660-908
Range on HMM: 1-130/130
Sequence Identity: 16% (46 aa)
GDQNRLKQILSNLIDNAIKFSNS----------SNINNSISIIVEQLTHNQFKKYKDSFRSNSKTHSRLNSHDDYSIDGDYDDQDNNDSYFGRDINVSDN
||..||.|.|.||.|||||.. . . . |.. |.
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------
ESAVGGFSELDEKDNSDDDDENDDENDETDENDDDTDDDTSSNTSRNNISNNLLFHNNTSGGGGGGINKREKFKKKDREGFVNLKFSIKDRGIGVPE---
....| |.|.|.
------------------------------------------------------------------------------------RITVEDNGPGIPPEMH
---DKHDFIFDRFFQVDG--------SYSRVQGG--VGLGLSICKKLIEFFGGAIWFESEASQGSTFHFILSIKS
.. . ||..|...|. | || || ||||||||...| .|| ||.| .||.| | ..
KSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE------TTFTFTLPLER
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| Kinase | DhkI.AA | HisK | 660-907 | 17 | 6.3e-21 | 72.12 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 660-907
Range on HMM: 1-164/164
Sequence Identity: 17% (50 aa)
GDQNRLKQILSNLIDNAIKFSNSSN--INNSISIIVE-------QLTHNQFKKYKDSFRSNSKTHSRLNSHDDYSIDGDYDDQDNNDSYFGRDINVSDNE
|.||.|||| ||| ||.|| . . .|.|.|| . .. | |
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNI----------------------------------------------KY-N-S---
SAVGGFSELDEKDNSDDDDENDDENDETDENDDDTDDDTSSNTSRNNISNNLLFHNNTSGGGGGGINKREKFKKKDREG--------FVNLKFSIKDRGI
|..|. | ....|..| |.
----------------------------------------------------------------------IFIQKIQENMVQEQLQQKNLIQISVQDTGC
GVPEDKHDFIFDRFFQVDG-------SYSRVQG-----GVGLGLSICKKLIEFFG--------GAIWFESEASQGSTFHFILSIK
| ||.. ||. | ..|. ... .. |.||||.||..|... | . | ..|| .|||| | . .
GMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
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| Kinase | DhkI.AA | Dicty3 | 1425-1537 | 31 | 8.2e-05 | 11.6 | In-house | 205-260 (351) | Show / Hide |
Range on Protein: 1425-1537 Range on HMM: 205-260/351 Sequence Identity: 31% (36 aa) NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTNTSNNHTSDPSKSSNSTPETSPPISSPRSNNNNNCSLTTIVGVTTPPQPSSTITTPQFQSPPILSGNS ||||||||||||||||||||||||||.||| . || |.|. . NNNNNNNNNNNNNNNNNNNNNNNNNNTNNNVKIINNN---------------------------------------------------------IYSNKQ GNINLLSSNGTSS . |. ||.. YKQKCYSICGTIH |
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| REC | DhkI.AA | REC | 1550-1670 | 26 | 1.7e-38 | 135.16 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1550-1670 Range on HMM: 1-150/150 Sequence Identity: 26% (43 aa) QKVLVAEDN----TMNQKLIK------TLLTKRGFD--------ITIAKDGK-------QALDFYHESKNKSI--------LYDCILMDIQMP------- ..|...|. ....... ||.| |.. ...| ||. .||. | . | . .|.|.|||.|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG ILSGLEATCAIREIEANEGGHIPIIAVTAHAMKGDKEKFLESGVDDYVTKPINPKLLYEVI ..|.|.. .|| |||..|||.. |... ||.|.|||.|||..|. | ..| GMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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| Response_reg | DhkI.AA | Response_reg | 1552-1671 | 33 | 4.3e-32 | 117.51 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 1552-1671 Range on HMM: 1-115/115 Sequence Identity: 33% (41 aa) VLVAEDNTMNQKLIKTLLT-KRGF-DITIAKDGKQALDFYHESKNKSILYDCILMDIQMPILSGLEATCAI-REIE-ANEGGHIPIIAVTAHAMKGDKEK ||...|. ........|. | |. ... | ||..||. .| . .|.|.|||.|| ..|||.. | |. . . .|||..|||... |... VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-----PDLIIMDINMPGMDGLELCRRIRRQHPHPQ----TPIIMCTAHGDEDDAVE FLESGVDDYVTKPINPKLLYEVIN |. | .||.|||..| |.. |. ALQAGANDYITKPFDPDELHAAIR |
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