Gene DhkC (Slime mold)

DhkC

Species: Slime mold
Alias: DhkC, DdisK266, DDB0185038
External Links: DictyBase Link ,
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
DhkC.AA Protein None 1225 None Fasta, JSON
DhkC.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of DhkC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA DhkC.AA HisKA 419-484 31 3.5e-18 66.34 Pfam 1-69 (69) Show / Hide 
Range on Protein: 419-484
Range on HMM: 1-69/69
Sequence Identity: 31% (22 aa)

KSIDMISHLSHELRTPIHSVIASIQLFRS-TILTVTQ--NEYLSIIDTSANTLLELVSNVLDYKRIRSG
   ......|||||||...... ..| .  | |.  |   |||..|. .|. ...|....||. ||..|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA DhkC.AA HisKA 419-484 24 1.4e-17 65.65 SMART 1-89 (89) Show / Hide 
Range on Protein: 419-484
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

KSIDMISHLSHELRTPIHSVIASIQLFRS----------TILTVTQ-------------NEYLSIIDTSANTLLELVSNVLDYKRIRSG
   ......|||||||...... ..| .           | |.  |              |||..|. .|. ...|....||. ||..|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HATPase_c DhkC.AA HATPase_c 531-653 28 9.3e-38 132.68 SMART 1-130 (130) Show / Hide 
Range on Protein: 531-653
Range on HMM: 1-130/130
Sequence Identity: 28% (43 aa)

GDPIRLRQVLLNLIGNGLKYTNK--------------GQVCISVEPEQVNEHCMYLHFQVKDSGIGIKE------ENMSKLFAGFSQVNN-------GGT
|||.||||||.||..|..|.| .              |.. ..|.           ...|.|.|.|| .      | ....|  | .. .       ...
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-----------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSR

TQEALG--SGLGLAISKDLVELMGGKIWCSSNATQNNGEAGCTFHFVIPLET
...  |  .||||.|.| .||..||.||..           .||.| .|||.
SRKYGGGLTGLGLSICKRIVEQHGGTIWVE-----------TTFTFTLPLER
HATPase_c DhkC.AA HATPase_c 531-652 32 3.5e-35 124.67 Pfam 1-120 (120) Show / Hide 
Range on Protein: 531-652
Range on HMM: 1-120/120
Sequence Identity: 32% (42 aa)

GDPIRLRQVLLNLIGNGLKYTNK-GQVCISVEPEQVNEHCMYLHFQVKDSGIGIKE------ENMSKLFAGFSQVNNGGTTQEALG--SGLGLAISKDLV
|||.||.||..||..|..|.| . |.. ..|...       .....|.|.|.|| .      |.....|  | .. . .. ..  |  .||||.|.. .|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIV

ELMGGKIWCSSNATQNNGEAGCTFHFVIPLE
|..||.||..|.      . |.||.| .|||
EQHGGTIWVESEP-----GGGTTFTFTLPLE
Kinase DhkC.AA HisK 531-628 26 5.2e-28 97.66 In-house 1-145 (164) Show / Hide 
Range on Protein: 531-628
Range on HMM: 1-145/164
Sequence Identity: 26% (38 aa)

GDPIRLRQVLLNLIGNGLKYTNKG----QVCISVEPEQVNEHCM------------------------YLHFQVKDSGIGIKEENMSKLFAGFSQV----
 || |..|.|.|||.| ||.|.||    |. |... || |..                          .. ..|.|.|.|..||.. |.|  |...    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-------NNGGTTQEALGSGLGLAISKDLVELMG--------GKI
       |.    .   | ||||.|.. |....|        ..|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGI
Response_reg DhkC.AA Response_reg 670-723 26 0.001048 15.84 Pfam 1-53 (115) Show / Hide 
Range on Protein: 670-723
Range on HMM: 1-53/115
Sequence Identity: 26% (15 aa)

VLVVDKNPYIQTVLCQYLE-GWNC-QVIKSSDIKEASNKLKDLRREQIEVVMIDID
||.||..| .. .| |.||  . .  |   .| .|| .... ..   . .. .||.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH---PDLIIMDIN
REC DhkC.AA REC 1077-1196 25 1.8e-35 125.12 SMART 1-150 (150) Show / Hide 
Range on Protein: 1077-1196
Range on HMM: 1-150/150
Sequence Identity: 25% (42 aa)

TKIMILDDN----PVSLKLMQ------RILESRGFE--------CYPFDCSE-------KAVAQLDQV-------------NPAIIFMDCEMP-------
 .|.| ||.    || .....      |.||. |.|        .  . . |        |...|..              .| .|.||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

KMNGFECTQLIRKREQESLCLLKDRKIIIALTAHINPEIQVKCFDAGMNDFISKPFKPQCLELIL
.|.|.| .. ||               ||.|||| ..|  |....||..|.|.|||.|. |   .
GMDGIELCRRIR--------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg DhkC.AA Response_reg 1079-1197 31 6.8e-24 88.15 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1079-1197
Range on HMM: 1-115/115
Sequence Identity: 31% (39 aa)

IMILDDNPVSLKLMQRILE-SRGF-ECYPFDCSEKAVAQLDQVNPAIIFMDCEMPKMNGFECTQLIRKREQ-ESLCLLKDRKIIIALTAHINPEIQVKCF
..| ||.|. ......||| . |. ..  .|  | |......  | .|.||..||.|.|.| .. ||....  .         ||..||| ...  |...
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ-------TPIIMCTAHGDEDDAVEAL

DAGMNDFISKPFKPQCLELILR
.||.||.|.|||.|. |  ..|
QAGANDYITKPFDPDELHAAIR