Gene Pdk1B (Slime mold)

Pdk1B

Species: Slime mold
Alias: DdisK016, Pdk1B, DDB0216246, pdkB
External Links: DictyBase Link ,
Annotation:

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
Pdk1B.AA Protein None 908 None Fasta, JSON
Pdk1B.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of Pdk1B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Pdk1B.AA PDK1 271-527 46 1.2e-190 589.77 In-house 1-307 (307) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-307/307
Sequence Identity: 46% (144 aa)

FDFIRTIGKGAYGKVKLVIEKET----QLIFASKILNKKLIIKEKKAKYVNTEKTILDSLDN-----PNIVKLFYTFQDENNLYFILEYCPNGDLLGALK
|.|...||.|.|..|.|..||||    . ..|.||..|..||.|||.|||..||.|...|.|     |.||||..|||||..|||.||||||||||...|
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK

K--AGCFSIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGKNQHLKLSDFGSA---KQLSIG-------------SHHKG---------SRSGSFC
|  .|.|..|..|||||||..|||.||..||.|||||||||||.|..|....|||.|   |.|...             .|.||         .|..||.
KQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSFV

GTAEYVCPELLTEKSAGVEADIWSYGCLLYQLVSGKLPFKGF-----NEYQTFLLITKREFSYPDN--FDKCCMNLIDQLLDLDPYKRPT-------ISE
||||||.|||||.|......|||..||..||.|.|..||.|.     |||.||  |.|.....|||  |..|...|...||..||..|.|       ...
GTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQ

IKNHEFF
||.|.||
IKAHPFF
Kinase Pdk1B.AA AGC 271-527 30 3e-152 396.86 In-house 1-395 (395) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-395/395
Sequence Identity: 30% (120 aa)

FDFIRTIGKGAYGKVKLVIEK------ETQLIFASKILNKKL-IIKEK--KAKYVNTE------------KTILDSLD----------NPNIVK-LFYTF
|.|...||||..||| || .|       |. ..| |.|.||  |.. |  . ....||            . ||  ..          .|.||| |.|.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDENN--LYFILEYCP---------NG-DLLGALK---KAGCFSIDVVRFYAAE-------ILIALEYLHG-KGIAHRD-LKPENILLGKNQHLKLSDFG
||...  |||..||.|          | .|.  |.   | |.|. ...||||||       |. ||||||  .|| ||| |||||||| .. |.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

SAKQLSIGSHH----------------------------------------------KGSRSGSFCG--TAEYVCPELLTEKSAGVEADIWS--YGCLLY
..|..  . .                                               |. |  .|||  |.||. || |     | ..|.||  .|||.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

QLVSGKLPFKGFN----------EYQTFLLITKR------EFSYP----------DNFDKCCMNLIDQLLDLDPYKRPT----------ISEIKNHEFF
....|. || | |          ....| .| ..      .  .|          ..|.. ...|| .||  || ||..          ..|||||..|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase Pdk1B.AA S_TKc 271-527 36 4.6e-100 339.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-231/231
Sequence Identity: 36% (101 aa)

FDFIRTIGKGAYGKVKLVIEKETQLIFASKILNKKLIIKEKKAKYVNTEKTILDSLDNPNIVKLFYTFQDENNLYFILEYCPN--GDLLGALKKAGC---
....|.|||||.|||.....|.|. |.| ||..          . .  |  || . . ||||||...||| ..||...|||..  |||.  .|| |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGKNQHLKLSDFGSAKQLSIGSHHKGSRSGSFCGTAEYVCPELLTEKSAGV-EADIWSYGC
   |.  ..|||...|. ||||.| .|| ||||||||||| .  |.|..|||.|.||            .|||| .|. ||.|   . |  ..|.|| ||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LLYQLVSGKLPFKGFNEYQTFLLITKREFSYPDNFDKCCMNLIDQLLDLDPYKRPTISEIKN-------HEFF
.|| ...|. ||   .....| .|           .. . ..|...|. || ||||. |. .       |..|
ILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Pdk1B.AA Pkinase 271-527 32 3.5e-95 327.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-293/293
Sequence Identity: 32% (98 aa)

FDFIRTIGKGAYGKVKLVIEKETQLIFASKILNKKLIIKEKKAKYVN-TEKTILDSLDNPNIVKLFYTFQDENNLYFILEYCPNG----DLLGALK--KA
. ..|.||.|..|.|.. ..| |. |.| ||..|. . ..|.   .. .|  |. .|. ||||.|...|.|....|...|||..|    ||   ..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GCF--SIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGKNQHL----KLSDFGSAKQLSIGSHHKGSRSGSFCGTAEYVCPELLT-EKSAGVEADI
|||  | ....||. .|| .|||.| .|| ||||||||||. .| |.    |..|||.|||..   . ..|   .|||| .|. ||..   .  | ..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSYGCLLYQLVSGKLPFKGF------NEYQTFLLITKREFSYPDNFD---------------------KCCMNLIDQLLDLDPYKRPTISEIKNHEFF
||.||.||....|..||.|       ...| . .| .......   .                     . |  .|. .|..||.||||. .|..|..|
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Pdk1B.AA RSK 274-527 36 3.6e-92 312.51 In-house 1-278 (278) Show / Hide 
Range on Protein: 274-527
Range on HMM: 1-278/278
Sequence Identity: 36% (103 aa)

IRTIGKGAYGKVKLVIEK---ETQLIFASKILNKKLIIKEKK-AKYVNTEKTILDSLD-NPNIVKLFYTFQDENNLYFILEYCPNGDLLGALKKAGC---
..  |.|.|||| |. ..    |. |.| |.|.|. |.. .| .... || .||      |.||.|.|.||.|  || |.|||. |.|.  |.| ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGK---NQHLKLSDFGSAKQLSIGSHHKGSRSGSFCGTAEYVCPELLT---EKS-AGVEADIWS
|| | ..||.|||  |.|.|| .|| ||||||||||.     . |.||.||| .||.   . .....  .||.|.||. ||.|.    ..  .  .|.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF---RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWS

YGCLLYQLVSGKLPFKG---FNEYQTFLLITKRE--FSYP--DNFDKCCMNLIDQLLDLDPYKRPT-----ISEIKNHEFF
 |.|.| . .|..||.|    |  ...  | | .  .. |  ..  . . .|| ..|  || ||..     ..|||.|..|
LGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase Pdk1B.AA CAMK 276-527 24 1e-90 292.47 In-house 1-425 (425) Show / Hide 
Range on Protein: 276-527
Range on HMM: 1-425/425
Sequence Identity: 24% (104 aa)

TIGKGAYGKVKLVIEKETQ------------LIFASKILNKKLIIK-------------------------EKKAKYVNTEKTILDS-------LDNPNI
|.|.|..|||||.|.|.|.              .| ||..|| . .                         .|. | |  |  |. .       || |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLFYTFQD-------------------ENNLYFIL---EYCPNG----DLLGALKKAGC---------------FSIDVVRFYAAEILIALEYLHGKGI
.||. ...|                   ....|...   |||..|    ||.  ... ||               |. . .|.|   |. |..|.| ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENILLGKNQ-----------------HLKLSDFGSAKQLSIGSHHK-------------------GSRSGSFCGTAEYVC-PELLTEKS----
.||||||||||| .|                   .|..||| |...  |.  .                   |     |||| ||.. ||.|  |.    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------AGVEADIWSYGCLLYQLVSGKLPFKGF-------------NEYQTFLLITKREFSYPDNFDKC------------------------CMN
           | ..|.|| |..|| ...|..|| |              |.|..|  |.| ....|. . .                         |..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIDQLLDLDPYKRPTISEIKNHEFF
|| ..|  || ||.||....||...
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Pdk1B.AA AktR 271-527 42 3e-90 306.14 In-house 1-268 (268) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-268/268
Sequence Identity: 42% (114 aa)

FDFIRTIGKGAYGKVKLVIEK-ETQLIFASKILNKKLIIKEKKAKYVNTEKTILD-SLDNPNIVKLFYTFQDENNLYFILEYCPNGDLLGALKKAGCFSI
|.... .||||.||| || .| ..| ..| |.. || ||........ ||..|.    ..| ||||.|.||....|.||.||||.|.|.  ||| . || 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DVVRFYAAEILIALEYLHGK-GIAHRDLKPENILLGKNQHLKLSDFGSAK-QLSIGSHHKGSRSGSFCGTAEYVCPELLTE-KSAGVEADIWSYGCLLYQ
...|||.|.||.|||||| .  |  ||||||||||... |.|..||| .| |  .   |.  .  ||||| ||. || .|. |  .  .|.|. |...| 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMM---HYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYE

LVSGKLPFKGFNEYQTFLLITKRE---FSYPDNFDKCCMNLID-QLLDLDPYKRPT-----ISEIKNHEFF
.|.|  ||   |  | |..| . .   | || .| . |..||  .||. .|.||..     ..|||.| .|
MVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase Pdk1B.AA Ciliate-E2 271-527 26 1.4e-87 297.27 In-house 1-365 (365) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-365/365
Sequence Identity: 26% (101 aa)

FDFIRTIGKGAYG-----KVKLVIE------------------KETQLIFASKILNKKLIIKEKKAKYVN----------TEKTILDSLDNPNIVKLFYT
..||. ||.|..|     ||..| .                  | .. |.| ||..|. |.  |. ....           || || .|..|||.|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DENNLYFILEYCPNGDLLGALK------------KAGCFSIDVVR---------------FYAAEILIALEYLHGKG-IAHRDLKPENILLGKNQH
||  |.||.|...|||  |||.  .|            . ..|..  ..               ||.|.|. |||||| |. | |||.||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKLSDFGSAKQLSI-------GSHHKGSRSGS---------------------FCGTAEYVCPELLTEKS---------AGVEADIWSYGCLLYQLVSGK
.|..||| .|....       ....|     .                     .|||..|..|| |  |.          . ..|||| |..||....||
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPFKGFNEYQTFLLITKREFSYP------------------DNFDKCCMNLIDQ----LLDLDPYKRPT-ISEIKNHEFF
.||        .  | . ....|                  .. .. |..|| .    .|. || ||.| ...|.||..|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Pdk1B.AA CAMKL 271-527 30 2.3e-87 278.83 In-house 1-297 (297) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-297/297
Sequence Identity: 30% (93 aa)

FDFIRTIGKGAYGKVKLVIE-KETQLIFASKILNKKLII-KEKKAKY-----------VNTEKTILDSLD---NPNIVKLFYTFQDENN------LYFIL
.....|.|||..||||| .  . |.   | ||..|| |  .... |            .  |  |. .|.    |||.||. .......      .| ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPNGD--LLGALKKAGC----FSIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGKNQ--HLKLSDFGSAKQLS---IGSHHKGSRSGSFCGTA
|||..|.  |.  ..| |.    .. .  |.|   |. |..|.| .||.|||.||||||| .|.   .|..||| . .     .|   .|     |||. 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFG---PGQKLKTFCGSP

EYVCPELLTE--K-SAGVEADIWSYGCLLYQLVSGKLPFKGFN-------EYQTFLLITKREFSYPDNFDKC--CMNLIDQLLDLDPYKRPTISEIKNHE
.| .||..    |   | ..|||| | .|| .| |.|||.. .        . ........   ||. . .   | .|| ..|  .| ||||| .|.||.
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHP

FF
..
WM
Kinase Pdk1B.AA Akt 271-527 39 1.1e-82 264.07 In-house 1-264 (264) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-264/264
Sequence Identity: 39% (107 aa)

FDFIRTIGKGAYGKVKLVIEKETQLIF-ASKILNKKLIIKEKKAKYVNTEKTILDSLDNPNIVKLFYTFQDENNLYFILEYCPNGDLLGALKKAGCFSID
|||.. .|||..||| || .| || .. | |.| |. ||. .. ... ||. ||   ..| ||.| | ||....|||...||. |.|   |.... || |
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

VVRFYAAEILIALEYLHGKGIAHRD-LKPENILLGKNQHLKLSDFGSAKQLSIGSH-HKG-SRSGSFCGTAEYVCPELLTEKSAGVEADIWS-YGCLLYQ
  |||.|||  |.|.|| |.|  || |||||||. |. |..| ||| .|.     . .|   .  .||||.||  || |  . ..  .|.|.  ||..| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKE-----NIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYE

LVSGKLPFKGFNEYQTFLLITKREFSYP--DNFDKCCMNLIDQLLDLDPYKRP-----TISEIKNHEFF
.  | .||   .  | | .|   .  .|  |.... | .|| .||  || ||.     .. |||.|..|
MMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase Pdk1B.AA Ciliate-E2-Unclassified 271-527 27 2.5e-81 276.5 In-house 1-352 (352) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

FDFIRTIGKGAYGKVKLVIEKETQLIFASKILNKKLIIKEKKAKYV-------NTEKT---------------ILDSLDNPNIVKLFYTFQDENNLYFIL
. .|..||.|..|||.....|......| |...|. |.| |. ...       ....                || ....|.|||.||.|||..|.|...
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCPNGDLLGALKK-----------------AGCFSIDVVR-----FYAAEILIALEYLHGKG-IAHRDLKPENILLGKNQ---HLKLSDFGSAK---QL
|||..|||.  .||                   .|.   ..     ||.|.|| .||||| |. | |||.||||||. .|.   ..|..|||..|   | 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

SIGSHHKG---------SRSGSFCGTAEYV----CPELLTEKSAG----VEADIWSYGCLLYQLVSGKLPFKGFNEYQ----------------TFLLIT
.    ...          .. .|||| .|      ||.| ..  .     ..|||| |..||... |..||.. |..|                 .  | 
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

KREFSYP--------DNFDKCCMNLID----QLLDLDPYKRPTISEIKNHEFF
......|        .. .... ..|     ..|. .| ||.|...|.|| .|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase Pdk1B.AA PKA 271-527 38 8.3e-80 271.45 In-house 1-263 (263) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-263/263
Sequence Identity: 38% (104 aa)

FDFIRTIGKGAYGKVKLVIEKETQLIFASKILNKKLIIKEKKAKYVNTEKTILDSLDNPNIV-KLFYTFQDENNLYFILEYCPNGDLLGALKKAGCFSID
|..|.|.|.| .|.|.|. .|..  ..|.|.|.|  |...|    |..||.|| ....|.|| |. .||||...||...||.| |..   | | |.|| .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

VVRFYAA-EILIALEYLHGKGIAHRDLKPENILLGKNQHLKLSDFGSAKQLSIGSHHKGSRSGSFCGTAEYVCPELLTEK-SAGVEADIWSYGCLLYQLV
. .|||| .|  |||||| . | .|||||||||. || |.|. ||| || .      .. |. . ||| ||  || .. |   |   | |. |.| | ..
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKV------DD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEML

SGKLPFKGF--NEYQTFLLITKREFSYPDNFDKCC---MNLIDQLLDLDPYKRP-TISE----IKNHEFF
.|. ||     .  |..  | . .  .| .||.       ||..||  |. ||  . ..    ||||..|
AGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase Pdk1B.AA TyrKc 271-527 23 4.7e-16 36.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 271-527
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FDFIRTIGKGAYGKVKLVIEKETQLIFASKILNKKLIIKEKKAKYVNTEKTILDSL--DNPNIVKLFYTFQDE-------NNLYFILEYCPNGDLLGALK
  .....| ||.|.| . . |   .  | | |..         .    |  |. .|  ..||||.|.    ..         |. ..||.|.|||.  |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KAGC-FSIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGKNQHLKLSDFGSAKQLSIG-------SHHKGSR--SGSFCGTAEYVCPELLTEKSAG
| .  .. .    ..  |    |||| |.. ||||   |.|.|.|.. | |||| .. .  .       .  . .   .| .        || . ..   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

VEADIWSYGCLLYQLVS-GKLPFKG-----FNEYQTFLLITKREFSY-PDN--------FDKCCMNLIDQLLDLDPYKRPTISEIKNHEFF
 . |.||.| ... . . |. |  |      . .. . .. ...    |.|          .   ... |  . || .||| |||  ||.|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase Pdk1B.AA Pkinase_Tyr 271-414 28 2.1e-12 42.61 Pfam 102-257 (270) Show / Hide 
Range on Protein: 271-414
Range on HMM: 102-257/270
Sequence Identity: 28% (45 aa)

FDFIRTIGKGAYGKVKLVIEK----ETQLIFASKILNKKLIIKE-KKAKYVNTEKTILDSL-DNPNIVKLFYTFQ-DENN--LYFILEYCPNGDLLGALK
  |....|.||.|.|.. . |    .|..  | |.|. .   .. ....  . |  |. .| ..||||.|      ..    .| ..||.|.||||  |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----AGCFSIDVVRFYAAEILIALEYLHGKGIAHRDLKPENILLGKNQHLKLSDFG
|     . ...     ....|  ..|||. |.. ||||   |.|...| . | .|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase Pdk1B.AA Pkinase_Tyr 452-489 21 0.753538 3.5 Pfam 193-233 (270) Show / Hide 
Range on Protein: 452-489
Range on HMM: 193-233/270
Sequence Identity: 21% (9 aa)

VEADIWSYGCLLYQLVS-GKLP-FKGFNEYQTFLLI-TKRE
.. |.||.| |.. ... |. | ..|   .. . .|  ...
TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase Pdk1B.AA Pkinase_Tyr 511-527 58 4.628053 0.83 Pfam 256-270 (270) Show / Hide 
Range on Protein: 511-527
Range on HMM: 256-270/270
Sequence Identity: 58% (10 aa)

DPYKRPTISEIKNHEFF
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DPEDRPTFSEI--HEQL
PDK1_PH Pdk1B.AA PDK1_PH 804-905 39 3.8e-54 186.2 In-house 1-112 (112) Show / Hide 
Range on Protein: 804-905
Range on HMM: 1-112/112
Sequence Identity: 39% (44 aa)

YQWSRFLLPNDEIILACGITEKRSGLIT----KKRQLIITDTPRIFYVDPVKMTQKGEITVD-GSLSAQQK-----SSKHFIINSKGRSRHFYDLDGQSK
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TPWHQFLMPEGEHILKCGWVYKRKGLFAKPKKKRRQLILTDGPRLFYVDPMTMVIKGEIPWSSKDLYVEYKPDRKNNFKHFFIHTPNRTYYFEDPKGCAN

LWVDLINELNML
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KWCEAIEKVCKR