Gene DDB0231558 (Slime mold)

DDB0231558

Species: Slime mold
Alias: DDB0231558, DdisK010
External Links: DictyBase Link ,
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
DDB0231558.AA Protein None 1350 None Fasta, JSON
DDB0231558.kin_dom Protein Kinase Domain None 327 None Fasta, JSON

Protein domain

Protein domains of DDB0231558.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0231558.AA NDR 756-1082 43 9.3e-212 660.28 In-house 1-350 (350) Show / Hide 
Range on Protein: 756-1082
Range on HMM: 1-350/350
Sequence Identity: 43% (152 aa)

FTLIEKIGEGGFGQVFLAKKKDTGEIVAIKRMSKELIWSKNKVSHIKNERDILAQGKN-HRWIVSLVYSFQDDQYLYLAMEYVPGGDLRS---LLSALNS
|. |. ||.|.||.|.|..|||||.|.|.|.| |.... ||.| |...||||.|. .| ..|.|.|.|||||.|||||.|||.||||...   ||. .. 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LDEDSARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISRDGHVKLADFGLSKNVVTRYHLRSASADNTINTTTSTPTTSSNINQLSSSMIEHTPMKFGAA
..|| ||||.||||.|..|.|..||.|||.||.|||| .|||.|| ||||......|.|.......... ||.|| .......... .| ||.|..| ..
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPM-TTYST-FHWTHNSWYYQNMKEHRPQDFMDN

ANGNG---------PLNSSV----TDFGSFKDLSVAARLAYSVVGSPFYMAPEVLQATRGYGDEVDWWSLGCMFYEFIFGVPPFDGDSPEEVMETVLKWK
.| |.         ......    .... ....    .||||.||.|.||||||.| ..||....|||||||..||...|.||| .|.|.|... ...||
WNSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWK

TMLQRP---DG----VSDELWDLISGLIN-DGSTRLGSGEKGVENIKNHIFF
.....|   ..    .|.| ||||  |.. | ..||||..|||..||.| ||
QTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase DDB0231558.AA AGC 756-1082 29 2.7e-162 423.43 In-house 1-395 (395) Show / Hide 
Range on Protein: 756-1082
Range on HMM: 1-395/395
Sequence Identity: 29% (126 aa)

FTLIEKIGEGGFGQVFLAKKK------DTGEIVAIKRMSKEL---IWSKNKVSHIKNE------------RDILAQGKN---------HRWIVS-LVYSF
| ..  ||.|.||.|.|..||      |||.. |.| ..|.    |  ||.| |...|            |.||.. ..         | .||. | |||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDDQY--LYLAMEYVP--------GGDLRSLLSALN-----SLDEDSARFYMAE-------MVEAVDSCHR-LGYCHRD-LKPENFLISRDGHVKLADFG
||...  ||. |||.|        ||.. ..|.  .     ..||. ||||.||       .| |... |. .|. ||| ||||| |. .|||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKNVVTRYHLRSASADNTINTTTSTPTTSSNINQLSSSMIEHTPMKFGAAANGNGPLNSSVTDFGSFKDLSVA-----------ARLAYSVVG--SPFY
|.| ...... ... ..  .  ..... ..... | .|.|   | .                .  .  . .. .             .... .|  .| |
LCKEGMNDGEKGQQ-SQ-SN--MKFHW-HNKKY-Q-KSNMD--T-N----------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEY

MAPEVLQATRGYGDEVDWWS--LGCMFYEFIFGVPPFDGDSPE----------EVMETVL------KWKTMLQRP--------DGVSDELWDLISGLIN-
||||.|     || ..||||  |||..||...| ||| ||.|.          |... ..      .||  . .|        . .|.|..|||..|.. 
MAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCK

DGSTRLGSGEK-----GVENIKNHIFF
| . |||.|..     |.| |||| .|
DPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase DDB0231558.AA S_TKc 756-1082 28 5.6e-100 339.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 756-1082
Range on HMM: 1-231/231
Sequence Identity: 28% (96 aa)

FTLIEKIGEGGFGQVFLAKKKDTGEIVAIKRMSKELIWSKNKVSHIKNERDILAQGKNHRWIVSLVYSFQDDQYLYLAMEYVPG--GDLRSLLSALNS--
.....|||.|.||.|.....|.||.|||||...           ||..|..|| .  .| .|| | ..||| ..||. |||..|  |||....   ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LDEDSARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISRDGHVKLADFGLSKNVVTRYHLRSASADNTINTTTSTPTTSSNINQLSSSMIEHTPMK
    ..|  |||||.....|.. ||..| .|||||||| |...  |.|..||||.. .                                          
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------

FGAAANGNGPLNSSVTDFGSFKDLSVAARLAYSVVGSPFYMAPEVLQATRGYGD-EVDWWSLGCMFYEFIFGVPPFDGDSPEEVMETVLKWKTMLQRPDG
                               ....|.|.|||||||    |||  ..||||.||..||.. | |||.   ...... ..           
-------------------------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------

VSDELWDLISGLIN-DGSTRLGSGEKGV--ENIKNHIFF
 |.|..|.|... . | . |..  |     . ||.| .|
-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0231558.AA DMPK 756-900 48 2.1e-87 215.83 In-house 1-145 (270) Show / Hide 
Range on Protein: 756-900
Range on HMM: 1-145/270
Sequence Identity: 48% (71 aa)

FTLIEKIGEGGFGQVFLAKKKDTGEIVAIKRMSKELIWSKNKVSHIKNERDILAQGKNHRWIVSLVYSFQDDQYLYLAMEYVPGGDLRSLLSALN-SLDE
|  .  || | ||.| . . | |... | | |.|    ..  ..  . ||||.. | | |||. | | |||..|||. ||| ||||| .|.|     ..|
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHG-NSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPE

DSARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISRDGHVKLADFG
| |||| |||| |..| |..|| ||| ||.| |..| ||.||||||
DMARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFG
Kinase DDB0231558.AA AktR 756-1082 30 1.7e-86 293.66 In-house 1-268 (268) Show / Hide 
Range on Protein: 756-1082
Range on HMM: 1-268/268
Sequence Identity: 30% (101 aa)

FTLIEKIGEGGFGQVFLAKKK-DTGEIVAIKRMSKELIWSKNKVSHIKNERDILAQGKNHRWIVSLVYSFQDDQYLYLAMEYVPGGDLRSLLSALNSLDE
|.... .|.|.||.|.|..|| |.....|.|  .|. |  .|. .|. .||.|..  .||  || |.|.||.. .|...|||.|||.| . |.  . ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DSARFYMAEMVEAVDSCHRL-GYCHRDLKPENFLISRDGHVKLADFGLSKNVVTRYHLRSASADNTINTTTSTPTTSSNINQLSSSMIEHTPMKFGAAAN
. ||||.|... |..  |       ||||||| |.  |||||..||||||                                                  
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK--------------------------------------------------

GNGPLNSSVTDFGSFKDLSVA---ARLAYSVVGSPFYMAPEVLQATRGYGDEVDWWSLGCMFYEFIFGVPPFDGDSPEEVMETVLKWK-TMLQRPDGVSD
                 | .      .|||..|.| |||||...   |..  ||||..|.  || ..| |||. .. ..  .  ..      . |  .|.
-----------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSS

ELWDLISG--LINDGSTRLGSGEKGVENIKNHIFF
.. ||| .  | ..   |||.. .| | ||.| .|
QCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase DDB0231558.AA RSK 759-1082 31 3.6e-82 279.28 In-house 1-278 (278) Show / Hide 
Range on Protein: 759-1082
Range on HMM: 1-278/278
Sequence Identity: 31% (108 aa)

IEKIGEGGFGQVFLAKKK---DTGEIVAIKRMSKELIWSKNK-VSHIKNERDILAQGKNHRWIVSLVYSFQDDQYLYLAMEYVPGGDLRSLLSALNS---
..  |.||.| ||| .|.   ||| | | |  .|  |  ..| . | . ||.||.  ..|  ||.| |.||....||| |||..||.|   |.   .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDEDSARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISR---DGHVKLADFGLSKNVVTRYHLRSASADNTINTTTSTPTTSSNINQLSSSMIEHTPMKF
..|| |.||||| | ||.  | .|  |||||||| |      .||.|| |||..|                                             
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

GAAANGNGPLNSSVTDFGSFKDLSVAA--RLAYSVVGSPFYMAPEVLQ---ATRGYGDEVDWWSLGCMFYEFIFGVPPFDG---DSPEEVMETVLKWK--
                        ..    .... ...  |||||.|      .|..  .||||||.  ||  .| ||| |   ....|.|. ..| |  
------------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFS

TMLQRPDGVSDELWDLISGLIN-DGSTRLGSGEKGVENIKNHIFF
 .. ... .|.|  |||...   | . |||.| ...| ||.| .|
LTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase DDB0231558.AA Ciliate-E2 756-1082 23 4.2e-72 245.87 In-house 1-365 (365) Show / Hide 
Range on Protein: 756-1082
Range on HMM: 1-365/365
Sequence Identity: 23% (100 aa)

FTLIEKIGEGGFGQVFLAKKKDTGE-----------------------IVAIKRMSKELIWSKNKVSHIK----------NERDILAQGKNHRWIVSLVY
. .|.|||.|.||.|...|.. ...                       |.|.|.|.|  | ..... ||           ||. || |  ||  |. ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQ-LNHPNIIKMYE

SFQ--DDQYLYLAMEYVPGGDLRSLLS------------ALNSLDEDSARFYMAEMVE---------------AVDSCHRLG-YCHRDLKPENFLISRDG
.||  ||...|| |||. ||||....             . ....|  ....|.. ..               |. ..|  .  .|||.|||| |.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

HVKLADFGLSKNVVTRYHLRS-----ASADNTINTTTSTPTTSSNINQLSSSMIEHTPMKFGAAANGNGPLNSSVTDFGSFKDLSVAARLAYSVVGSPFY
 .|..||||||.. . .  |.         .  | |. ||. ..   |                                     .   ......|.| |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD---Q------------------------------------IIQQNMFNTICGTPGY

MAPEVLQ--------ATRGYGDEVDWWSLGCMFYEFIFGVPPFDGDSPEEVMETVLKWKT--MLQRP------------------DGVSDELWDLISG--
||||.|.        .  ||. ..|.||||...||..|| |||            .. .    .. |                  . .|.|  |||.   
MAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFG

---LINDGSTRLGSGEKGVENIKNHIFF
   |  | . |..    | | |.|| .|
KRMLQKDPEKRIT----GWEQILNHPWF
Kinase DDB0231558.AA MAST 756-903 44 5.8e-68 218.08 In-house 154-300 (334) Show / Hide 
Range on Protein: 756-903
Range on HMM: 154-300/334
Sequence Identity: 44% (66 aa)

FTLIEKIGEGGFGQVFLAKKKDTGEIVAIKRMSKELIWSKNKVSHIKNERDILAQGKNHRWIVSLVYSFQDDQYLYLAMEYVPGGDLRSLLSALNSLDED
|. |. |. |..|.|.|.|.|.|....|.|.. |     || |.. . ||.|||. .|  ..|.. |||| ..||.. |||. |||. |||......||.
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNP-FVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEW

SARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISRDGHVKLADFGLSK
 |..|.||.| ...  |. |  ||||||.| ||. .||.||.||||||
MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase DDB0231558.AA MAST 756-903 41 1.9e-67 204.86 In-house 157-306 (337) Show / Hide 
Range on Protein: 756-903
Range on HMM: 157-306/337
Sequence Identity: 41% (63 aa)

FTLIEKIGEGGFGQVFLAKKKDTGEIVAIKRMSKELIWSKNKVSHIKNERDILAQGKNHRWIVSLVYSFQD--DQYLYLAMEYVPGGDLRSLLSALN-SL
|  |. |. |..|.|.|.|.|.|....|.|.. .  .  || | ... ||.||.. .|  ..|.. ||||   ..||.. |||. |||  |||.... ..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNP-FVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCM

DEDSARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISRDGHVKLADFGLSK
.|. |..|.|| | ...  |  |  ||||||.| ||  .||.||.||||||
PEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase DDB0231558.AA Akt 756-908 46 1.4e-60 192.29 In-house 235-389 (264) Show / Hide 
Range on Protein: 756-908
Range on HMM: 235-389/264
Sequence Identity: 46% (72 aa)

FTLIEKIGEGGFGQVFLAKKKDTGEIV-AIKRMSKELIWSKNKVSHIKNERDILAQGKNHRWIVSLVYSFQDDQYLYLAMEYVPGGDLRSLLSALNSLDE
|.... .| | ||.|||.|||||...  |.|  .|. |  ||.| |.| || || |  ||  ||.|.||||. ..||. |.|..||.| ..|.  .  .|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNIL-QHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

DSARFYMAEMVEAVDSCHRLGYCHRD-LKPENFLISRDGHVKLADFGLSK-NVVTR
| |||| ||.. | .  |  .   || ||||| |...|||..|.||||.| |....
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKD
Kinase DDB0231558.AA SGK 756-903 36 4.7e-55 168.23 In-house 1-173 (283) Show / Hide 
Range on Protein: 756-903
Range on HMM: 1-173/283
Sequence Identity: 36% (64 aa)

FTLIEKIGEGGFGQVFLAKKKDT------------------GEIVAIKRMSKELIW-------SKNKVSHIKNER-DILAQGKNHRWIVSLVYSFQDDQY
| .. .||.|.|| |...|.||.                  . . |.|  .|. |         |... ||. || .||   | |  ||.| |.|| ...
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMK-HPFIVNLHYAFQTKWK

LYLAMEYVPGGDLRSLLSALNSLDEDSARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISRDGHVKLADFGLSK
||. |.|| ||.. . |   ... || ||||.|| | | .  | .   .||||||| |   .||..| ||||.|
LYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK
Kinase DDB0231558.AA Pkinase 756-903 37 1.9e-54 192.02 Pfam 1-160 (293) Show / Hide 
Range on Protein: 756-903
Range on HMM: 1-160/293
Sequence Identity: 37% (60 aa)

FTLIEKIGEGGFGQVFLAKKKDTGEIVAIKRMSKELIWSKNKVSHIK-NERDILAQGKNHRWIVSLVYSFQDDQYLYLAMEYVPGG----DLRSLLS--A
.....|||.|.||.|.....|.||.|||.|...|. . |. ...|.. .|  |..   ||  || | ..|.|....|. |||..||    || ...|  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

LNSL--DEDSARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISRDGHV----KLADFGLSK
 ...  .|. ..||| ....... ||. | .||||||||.||...||.    |..||||.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK
Kinase DDB0231558.AA MAST 980-1082 38 4.9e-35 104.01 In-house 227-337 (337) Show / Hide 
Range on Protein: 980-1082
Range on HMM: 227-337/337
Sequence Identity: 38% (44 aa)

SVVGSPFYMAPEVLQATRG-YGDEVDWWSLGCMFYEFIFGVPPFDGDSPEE-VMETVLKWKTMLQRPDG--------VSDELWDLISGLIN-DGSTRLGS
...|.| |.||||.   .| ||  |||||.| . |||. |.||| ||.||| . . ... . ..  |..        .|.|  |||. | . . ..|||.
QCCGTPDYIAPEVI-LGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGA

GEKGVENIKNHIFF
.  |.. ||.| ||
N--GADEIKQHPFF
Kinase DDB0231558.AA DMPK 982-1082 40 2e-33 79.31 In-house 162-270 (270) Show / Hide 
Range on Protein: 982-1082
Range on HMM: 162-270/270
Sequence Identity: 40% (45 aa)

VGSPFYMAPEVLQATRG-----YGDEVDWWSLGCMFYEFIFGVPPFDGDSPEEVMETVLKW-KTMLQRPDGVS----DELWDLISGLINDGSTRLGSGEK
|| | |..||||||  .     || |.||||.|   || ..|  ||  ||  |     .   |..|. || ..     |  |||  |. | ..||| .  
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRN--

GVENIKNHIFF
|.| .|.| ||
GYEDFKCHPFF
Kinase DDB0231558.AA SGK 983-1082 41 8.6e-30 88.8 In-house 187-283 (283) Show / Hide 
Range on Protein: 983-1082
Range on HMM: 187-283/283
Sequence Identity: 41% (42 aa)

GSPFYMAPEVLQATRGYGDEVDWWSLGCMFYEFIFGVPPFDGDSPEEVMETVLKWKTMLQRPDGVSDELWDLISGLIN-DGSTRLGSGEK-GVENIKNHI
|.| |.|||||.  .... .||||.|||  ||...| |||     ..  .  .. .  ||.| ..| . |||| || . | . |||.  | . . ||||.
GTPEYLAPEVLRK-QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQP--LQIPPQMSNDAWDLIQGLLQKDPKKRLGT--KRDFMEIKNHP

FF
||
FF
Kinase DDB0231558.AA MAST 980-1082 35 1.2e-29 92.47 In-house 223-334 (334) Show / Hide 
Range on Protein: 980-1082
Range on HMM: 223-334/334
Sequence Identity: 35% (41 aa)

SVVGSPFYMAPEVLQATRG-YGDEVDWWSLGCMFYEFIFGVPPFDGDSPEEVMETVLKWK---TMLQRP------DGVSDELWDLISGLIND-GSTRLGS
...|.| |.||||.   .| .|  |||||.| ..|||. |.|||..|.|||. . .|. .   ...  .      .  | |  |||. | .   ..|||.
QCCGTPDYIAPEVILG-QGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGA

GEKGVENIKNHIFF
.  |.. .|.| ||
NN-GADEVKQHPFF
Kinase DDB0231558.AA Pkinase 962-1082 25 4.6e-27 96.79 Pfam 153-293 (293) Show / Hide 
Range on Protein: 962-1082
Range on HMM: 153-293/293
Sequence Identity: 25% (38 aa)

VTDFGSFKDL-SVAARLAYSVVGSPFYMAPEVLQATRGYGDEVDWWSLGCMFYEFIFGVPPFDGD------SPEEVMETVLKWKTMLQRPDGVS------
..|||. | .     . .....|.|.||||||..  ..|| .||.||.||..||...| |||.|.      .. .... ... ... ..|   |      
ICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFF

-------------DELWDLISGLIN-DGSTRLGSGEKGVENIKNHIFF
             .|. |.|..... | . |..      | |..| .|
RHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase DDB0231558.AA Akt 978-1082 37 3.2e-25 77.52 In-house 159-264 (264) Show / Hide 
Range on Protein: 978-1082
Range on HMM: 159-264/264
Sequence Identity: 37% (41 aa)

AYSVVGSPFYMAPEVLQATRGYGDEVDWWS-LGCMFYEFIFGVPPFDGDSPEEVMETVLKWKTMLQRP--DGVSDELWDLISGLIN-DGSTRLGSGEKGV
.... |.| |.|||.|.   |..  ||||. ||| .||...| |||  .  .. ..  .  .  .. |  | .|.|  |||||| | | . |||.|....
TKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQP--VKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDA

ENIKNHIFF
. ||.| .|
QEIKRHPWF
Kinase DDB0231558.AA TyrKc 756-1076 18 1.2e-12 -18.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 756-1076
Range on HMM: 1-280/280
Sequence Identity: 18% (68 aa)

FTLIEKIGEGGFGQVFLAKKKDTGEIVAIKRMSKELIWSKNKVSHIKNERDILAQG-KNHRWIVSLVYSFQDD-------QYLYLAMEYVPGGDLRSLLS
 ||..|.||| ||.|.... |   . ||.| . ..       .  . .|  |. .  ..|  || |.    ..       . |.. |||.|.|||.. | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ALNSLDEDSARFYMAEMVE-AVDSC------HRLGYCHRDLKPENFLISRDGHVKLADFGLSKNVVTR-YHLRSASADNTINTTTSTPTTSSNINQLSSS
.          . |..... ... .      |. .. ||||   | |......|| .|||||...     .                             
KHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG----------------------------

MIEHTPMKFGAAANGNGPLNSSVTDFGSFKDLSV----AAR--LAYSVVGSPFYMAPEVLQATRGYGDEVDWWSLGCMFYEFI-FGVPPFDG-----DSP
                           | .  ..     ..  | .        ||||..  .. .  . | || | . .|   .| .|  |      |.
--------------------------ESKDYYRKKEHKGGKTMLPI------RWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSN

EEVMETVLKWKTMLQRPDG-------VSDELWDLISGLIND------GSTRLGSGEKGVENI
.||.| | . . | | |..        .||. ....   .         . .      .| .
QEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase DDB0231558.AA Pkinase_Tyr 756-846 31 2.2e-11 39.18 Pfam 96-193 (270) Show / Hide 
Range on Protein: 756-846
Range on HMM: 96-193/270
Sequence Identity: 31% (31 aa)

FTLIEKIGEGGFGQVFLAKKK----DTGEIVAIKRMSKELIWSKN-KVSHIKNERDILAQGKNHRWIVSLVYSFQ-DDQY--LYLAMEYVPGGDLRSLL
 |...|.||| ||.|.... |    .|.  ||.| . ||   ... .     .|  |. |  .|  ||.|.     ...   .|. |||.|.|||.. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL
Kinase DDB0231558.AA Pkinase_Tyr 887-905 36 0.007351 10.31 Pfam 143-161 (270) Show / Hide 
Range on Protein: 887-905
Range on HMM: 143-161/270
Sequence Identity: 36% (7 aa)

LISRDGHVKLADFGLSKNV
|......|| .||||.. .
LVTENNVVKICDFGLARDI