Gene DDB0216386 (Slime mold)

DDB0216386

Species: Slime mold
Alias: DDB0216386, DdisK005
External Links: DictyBase Link ,
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
DDB0216386.AA Protein None 411 None Fasta, JSON
DDB0216386.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of DDB0216386.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0216386.AA MAST 86-348 43 1.7e-191 590.98 In-house 1-337 (337) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-337/337
Sequence Identity: 43% (145 aa)

YYFIKPISKGGYGQVFLAITK-SNKFFAIKSINKRDTIGKHMVKELMVERNILVQYQNQSIVKLFECFQT--KKKLYMVMEFLHGGDCASLLHSLN-TLE
..|||.||||.||.|.|...| .|..||.|.||..||| |..|....||||||..|||...||.|..|||  ||.|.||||...||||||||.... ...
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EREAKNIIAQIVNGLEFIHSCGIIHRDLKVENLIFDKNGIIKIVDFGFSEVGFTG-----------------------NSIKNGNKK-------------
|..||..||..|..||..||.||.|||||..|...|.||.||..|||.|.|||..                       ...|| ...             
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

------------------------NNKCLGTPYYMSPEVINKRG-YGKTIDWWALGIIIFELLSGETPFVGDNQN-MIFEKITNYTNEINFPSY------
                        |..|.|||.|..||||...| |||..|||..|||..|.|.|..||.||... |||..|.|...||..|..      
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

--FSEVAIDLIQKLLQVDPLKRLGANGADEVKRHPFF
  .|..|.|||.||||..|.||||||||||.|.||||
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
Kinase DDB0216386.AA MAST 86-348 42 6.00000000001e-172 558.9 In-house 1-334 (334) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-334/334
Sequence Identity: 42% (142 aa)

YYFIKPISKGGYGQVFLAITK-SNKFFAIKSINKRDTIGKHMVKELMVERNILVQYQNQSIVKLFECFQTKKKLYMVMEFLHGGDCASLLHSLNTLEERE
..||||||||.||.|.|...| .|..||.| |.|.|.| |.||....|||||| .|||. .||.|..||||..|.||||...|||||||||......|. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AKNIIAQIVNGLEFIHSCGIIHRDLKVENLIFDKNGIIKIVDFGFSEVGFTG----------------------NSIKNGNKK-----------------
||..||..|..||..||.||.|||||..|...|.||.||..|||.|.|||.                       |........                 
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

--------------------NNKCLGTPYYMSPEVINKRG-YGKTIDWWALGIIIFELLSGETPFVGDNQNMIFEKITNYT---NEINFP------SYFS
                    |..|.|||.|..||||...| .||..|||..|||..|.| | .||..|....||..|.|..   .|....      ...|
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

EVAIDLIQKLLQVDPLKRLGAN-GADEVKRHPFF
..|.|||.||||.||.|||||| ||||||.||||
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase DDB0216386.AA AGC 86-348 29 1.4e-154 402.98 In-house 1-395 (395) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-395/395
Sequence Identity: 29% (118 aa)

YYFIKPISKGGYGQVFLAITK-------SNKFFAIKSINKRD---TIGKHMVKELMVE------------RNILVQYQ----------NQSIVK-LFECF
. |.|.|.||..|.|.|.  |       ..|..|.| ..|..    . |.||.  |.|            ||||....          .. ||| |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTKKK--LYMVMEFLH--------GGDCASLLHSLN-----TLEEREAKNIIAQ-------IVNGLEFIHS-CGIIHRD-LKVENLIFDKNGIIKIVDFG
|.|..  ||.|||..         ||.| ..||  .     ...| .|. ..|.       || .||..||  |||||| || ||. .|..| ||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSEVGFTGN---------------------------------SIKNG-----------NKKNNKCLG--TPYYMSPEVINKRGYGKTIDWWA--LGIIIF
.. .| ...                                   .|.           .....   |  || ||.||..    |||. |||.  ||....
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLSGETPFVGDN----------QNMIFEKITNY----TNEINFP----------SYFSEVAIDLIQKLLQVDPLKRLGAN-------GADEVKRHPFF
|.|.| .|| |||          .. .|.|| |.    .... ||          ..||. | |||.|||..|| ||||..       ||.|.|.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase DDB0216386.AA S_TKc 86-348 35 1.9e-97 330.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-231/231
Sequence Identity: 35% (97 aa)

YYFIKPISKGGYGQVFLAITKS-NKFFAIKSINKRDTIGKHMVKELMVERNILVQYQNQSIVKLFECFQTKKKLYMVMEFLHG--GDCASLLHSLNT---
| ....| ||..|.|.... |. .. .||| |.          . .. |..|| . .   ||||...||. ..||||||.. |  ||  ..... ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LEEREAKNIIAQIVNGLEFIHSCGIIHRDLKVENLIFDKNGIIKIVDFGFSEVGFTGNSIKNGNKKNNKCLGTPYYMSPEVINKRGYGK-TIDWWAL
   . | .|. ...||...||..|| |||||||| ||. .|.   ||| |||.. .              . . |||.||.|||.   ||||  .|||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GIIIFELLSGETPFVGDNQNMIFEKITNYTNEINFPSYFSEVAIDLIQKLLQVDPLKRLGANGADE----VKRHPFF
|.|..|.|.|..||   ...|.|.||             |. |.|.|.|.||.|| ||..|  | .    .| ||.|
GCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0216386.AA AktR 86-348 40 1.1e-90 307.61 In-house 1-268 (268) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-268/268
Sequence Identity: 40% (111 aa)

YYFIKPISKGGYGQVFLAITK--SNKFFAIKSINKRDTIGKHMVKELMVERNILV-QYQNQSIVKLFECFQTKKKLYMVMEFLHGGDCASLLHSLNTLEE
. ..|.. ||..|.|.|.  |  ..|..|.|.| | . | . . . .  ||||.  . ..  ||||..|||||.||. .||.  ||.  . | . ....|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

REAKNIIAQIVNGLEFIHSC-GIIHRDLKVENLIFDKNGIIKIVDFGFSEVGFTGNSIKNG---NKKNNKCLGTPYYMSPEVINK-RGYGKTIDWWALGI
 .|. ..|||. .||. |.   || |||| ||.  |..| .||.||| |.       . .    . |... .||| ||.||.|.|  |..|..||||.||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGI

IIFELLSGETPFVGDNQNMIFEKITNYT-NEINFPSYFSEVAIDLIQ-KLLQVDPLKRLG--ANGADEVKRHPFF
 |.|...| .||  .||| .|.|| ... |....|||||. . |||| |||. .| ||||  .||..|.|.||.|
FIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase DDB0216386.AA RSK 89-348 35 1.1e-84 287.65 In-house 1-278 (278) Show / Hide 
Range on Protein: 89-348
Range on HMM: 1-278/278
Sequence Identity: 35% (101 aa)

IKPISKGGYGQVFLAITK----SNKFFAIKSINKRDTIGKHM-VKELMVERNILVQYQ-NQSIVKLFECFQTKKKLYMVMEFLHGGDCASLLHSLNT---
.|   .|||| |||   .    ... .| | ..|.  . .   ..  | |||||  .|  . ||.|.. |||..|||..||...||.    |    .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LEEREAKNIIAQIVNGLEFIHSCGIIHRDLKVENLIFDK---NGIIKIVDFGFSEVGFTGNSIKNG-NKKNNKCLGTPYYMSPEVIN----KRGYGKTID
. |.||. ..|.||  .|..|. |||||||| || ..|    .| ||..||||.  .      ..  |.. ..  .|  || ||...    ..|..|  |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACD

WWALGIIIFELLSGETPFVG---DNQNMIFEKITNYTNEINFP--SYFSEVAIDLIQKLLQVDPLKRLG--ANGADEVKRHPFF
|| ||....|.|.| .|| |   .|.. |...| . .   ..|  .| |. | |||.|.|..|| ||||   ..|.|.|.||.|
WWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase DDB0216386.AA CAMK 91-348 22 6.6e-82 263.59 In-house 1-425 (425) Show / Hide 
Range on Protein: 91-348
Range on HMM: 1-425/425
Sequence Identity: 22% (98 aa)

PISKGGYGQVFLAITK-SN------------KFFAIKSINKRDTIGKH-------------------------MVKELMVERNILVQ-------YQNQSI
 . .|..|.|.|.| | ..            . .||| |.|.   .|.                         . |... | .|. .        .   |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLFECFQ------------TKKK--------LYMVM---EFLHGG----DCASLLHSL---------------NTLEEREAKNIIAQIVNGLEFIHSCG
.||.| ..            | .|        .||||   |.  ||    |. . . .                  ..||||. .. ||. .....||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKVENLIFDKN-----------------GIIKIVDFGFSEVGFTGNS------IKNGNKKNNK-------------CLGTPYYMS-PEVINK---
|.||||| ||. .|.|                 . |||.||||. . . |..      .|.|.   ..             . |||.||. |||.|.   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-----------RGYGKTIDWWALGIIIFELLSGETPFVGD-------------NQNMIFEKITNYTNEINFPS----------------------YFSEV
           ..||. .| |..|.| . .|.|. || ||             |.. .||||..   .   |                       ..|. 
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

AIDLIQKLLQVDPLKRLGANGADEVKRHPFF
..|||.|.||||| ||.    ......||..
CKDLIRKMLQVDPEKRM---TIEQCLNHPWM
Kinase DDB0216386.AA Pkinase 86-348 30 1.5e-80 278.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-293/293
Sequence Identity: 30% (94 aa)

YYFIKPISKGGYGQVFLAITKSN-KFFAIKSINKRDTIGKHMVKELMV--ERNILVQYQNQSIVKLFECFQTKKKLYMVMEFLHGG----DCASLLH--S
| ....| .|..|.|.... |.. | .|.| |.|| .. . . ...    |  |.   .   ||.|...|..|...|||||.. ||    | .....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

LNTL--EEREAKNIIAQIVNGLEFIHSCGIIHRDLKVENLIFDKNGII----KIVDFGFSEVGFTGNSIKNGNKKNNKCLGTPYYMSPEVIN-KRGYGKT
 ...  .|.|.|... ||. |||..||.|||||||| ||. .|.|| |    || |||....          |  ..   |||.||.||||.  ..||. 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

IDWWALGIIIFELLSGETPFVGD------NQNMIFEKITNYTNEINFPSYFS-------------------EVAIDLIQKLLQVDPLKRLGANGADEVKR
.|.|..|.|..|.|.|..|| |.      .|. ....|    .. ..|   |                   | ..|.| ..|..|| ||..   |.... 
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQ

HPFF
||.|
HPWF
Kinase DDB0216386.AA Ciliate-E2 86-348 25 2.2e-80 273.34 In-house 1-365 (365) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YYFIKPISKGGYGQVFLAITKSN------------------------KFFAIKSINKRDTIGKHMVKELM----------VERNILVQYQNQSIVKLFEC
| ||| | .|..|.|...  ...                        |..|.|...|.. . . ... .|           |.||| | ..  |.|..||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TKKKLYMVMEFLHGGD--------CASLLHSLN---TLEEREAKNIIAQIVN---------------GLEFIHSCG-IIHRDLKVENLIFDKNGII
||  .....|.|||.. |||        . . .| ..    . |.|.|.|..||..               .||..|| . |||||.| ||..|     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIVDFGFSE------VGFTGNSIKNGNKKNNK---------------------CLGTPYYMSPEVINKRG---------YGKTIDWWALGIIIFELLSGE
||.|||.|          |.    ...... |                     ..|||.||.||..|. .         |.. .|.|.||.|..|.|.|.
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

TPFVGDNQNMIFEKITNYTNEINFP------------------SYFSEVAIDLIQK----LLQVDPLKRLGANGADEVKRHPFF
.||           . .  ..|.||                   . |. ..|||.|    .||.|| ||..  |..... ||.|
PPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase DDB0216386.AA Ciliate-E2-Unclassified 86-348 25 9.4e-78 264.63 In-house 1-352 (352) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-352/352
Sequence Identity: 25% (92 aa)

YYFIKPISKGGYGQVFLAITKSNKFF-----AIKSINKRDTIGKH-----MVKELMVERN-------------ILVQYQNQSIVKLFECFQTKKKLYMVM
| .|| | .||.|.|.... |..|..     ..|.... . . ..     . .. | ...             ||.. ..  |||.|.|||.|...|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFLHGGDCASLLHSLNT-----------------LEEREAK-----NIIAQIVNGLEFIHSCG-IIHRDLKVENLIFDKNG---IIKIVDFGFSE-----
|.. |||    . . ..                 ..|..||     ...|||..|||..|. . |||||.| ||..||.||    ||| |||.|      
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

VGFTGNSI-----KNGNKKNNKCLGTPYYM----SPEVINKRGYGKT----IDWWALGIIIFELLSGETPFVG--------------------DNQNMIF
.... ..       . ... . . |||.||    .|||. . .|...    .|.|.||.|..|.| |. || .                      .. |.
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

EKITNYTNEIN--FPSYFSEVAIDLIQ----KLLQVDPLKRLGANGADEVKRHPFF
.|.... .. .  .|   |. |.|.|.    |.|...| ||.   ...... ||.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF
Kinase DDB0216386.AA NDR 86-246 35 3.7e-44 133.68 In-house 1-167 (350) Show / Hide 
Range on Protein: 86-246
Range on HMM: 1-167/350
Sequence Identity: 35% (59 aa)

YYFIKPISKGGYGQVFLAITK-SNKFFAIKSINKRDTIGKHMVKELMVERNILVQYQ--NQSIVKLFECFQTKKKLYMVMEFLHGGDCAS---LLHSLNT
. .||.|.||..|.|.|.  | .....|.| ..| . . |. |. .  || |... .  |. .|||.  || |. || |||.. |||  .   ||  ...
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LEEREAKNIIAQIVNGLEFIHSCGIIHRDLKVENLIFDKNGIIKIVDFGFSEVGFTGNSIKNGNKKN
..| .|.  || .|  .| .|. |.||||.| .|.  || | ||  ||| .  |...   |.  .|.
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKK
Kinase DDB0216386.AA NDR 251-348 43 3.3e-43 130.68 In-house 243-350 (350) Show / Hide 
Range on Protein: 251-348
Range on HMM: 243-350/350
Sequence Identity: 43% (47 aa)

GTPYYMSPEVINK-RGYGKTIDWWALGIIIFELLSGETPFVGDNQNMIFEKITNYTNEI-----NFP--SYFSEVAIDLIQKLLQVDPLKRLGANG--AD
||| || |||... .||..|.||| || | .|.| | .||..|. . ...|| |. .       .||    .|. | |||..|. .|| .|||..|  .|
GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVD

EVKRHPFF
|.| ||||
EIKSHPFF
Kinase DDB0216386.AA Akt 251-348 42 3e-42 132.79 In-house 164-264 (264) Show / Hide 
Range on Protein: 251-348
Range on HMM: 164-264/264
Sequence Identity: 42% (44 aa)

GTPYYMSPEVINKRGYGKTIDWWA-LGIIIFELLSGETPFVGDNQNMIFEKITNYTNEINFP--SYFSEVAIDLIQKLLQVDPLKRLG--ANGADEVKRH
||| |..||..|. |..|. |||. ||....|.. |  ||  ...   |.|| |  ....||  ...|  . ||| .||. || ||||   |.|.|.|||
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKN--QPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRH

PFF
|.|
PWF
Kinase DDB0216386.AA Akt 86-230 38 1.4e-36 114.42 In-house 1-148 (264) Show / Hide 
Range on Protein: 86-230
Range on HMM: 1-148/264
Sequence Identity: 38% (57 aa)

YYFIKPISKGGYGQVFLAITKS-NKFF-AIKSINKRDTIGKHMVKELMVERNILVQYQNQSIVKLFECFQTKKKLYMVMEFLHGGDCASLLHSLNTLEER
 .|.| . || .|.|||.  |. .|.. |.|.. |.  | |  |.  . |||||. .... ||.|   |||..|||.||..  ||.  ..|.  ..  | 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EAKNIIAQIVNGLEFIHSCGIIHRD-LKVENLIFDKNGIIKIVDFGFS
.|.  .|.|. ..|. ||..|| || || ||.  ||.| |.. ||| .
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC
Kinase DDB0216386.AA TyrKc 86-348 21 4.4e-15 21.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 86-348
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YYFIKPISKGGYGQVFLAITKSNKFFAIKSINKRDTIGKHMVKELMVERNILVQY--QNQSIVKLFECFQTK-------KKLYMVMEFLHGGDCASLLHS
  ..| .  | .|.|.... |     |.|....        ....| | .|. ..  ... ||.|. .  ..       . |..|||.  .||. . |..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LNT-LEEREAKNIIAQIVNGLEFIHSCGIIHRDLKVENLIFDKNGIIKIVDFGFSEVGFTG-------NSIKNGNKKNNKCLGTPYYMSPEVINKRGYGK
    |  ..  ..  || .| |..|| ..|||||   |   ..|...|| ||| |  .  .         ..   .|. | .     |.||.||.. .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

TIDWWALGIIIFELLS-GETPFVG------DNQNMIFEKITNYTNEINFPSY--------FSEVAIDLIQKLLQVDPLKRLGANGADEVKRHPFF
  | |. |. ..|... |..|  |      .|| .|    . |  ..  | .         ..   .....  . || .|   .       | .|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQ--PPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase DDB0216386.AA Pkinase_Tyr 86-209 24 2e-07 25.77 Pfam 1-137 (270) Show / Hide 
Range on Protein: 86-209
Range on HMM: 1-137/270
Sequence Identity: 24% (34 aa)

YYFIKPISKGGYGQVFLAITK-----SNKFFAIKSINKRDTIGKH-MVKELMVERNILVQY-QNQSIVKLFECFQ-TKKK--LYMVMEFLHGGDCASLLH
  |.| . .| .|.|.... |      .   |.|.. | ..  .. . ...| | .|. |. ... ||.|  .    ..   .|.|||.  .||  . |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

S----LNTLEEREAKNIIAQIVNGLEFIHSCGIIHRDL
.     . |   .  .. .|| .|.|. .| ..|||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL