Gene YANK3 (Human)

YANK3

Species: Human
Alias: STK32C, RP11-140A10.1, MGC23665, PKE, YANK3
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 10q26.3,

Classification

Group: AGC
Family: YANK

Sequence

Name Sequence Type Origin Length Description Download
YANK3.NA RNA Sugen Kinome 2141 None Fasta, JSON
YANK3.AA Protein Sugen Kinome 486 None Fasta, JSON
YANK3.kin_dom Protein Kinase Domain Sugen Kinome 261 None Fasta, JSON

Protein domain

Protein domains of YANK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YANK3.AA YANK 93-353 75 3.4e-230 771.02 In-house 1-261 (261) Show / Hide 
Range on Protein: 93-353
Range on HMM: 1-261/261
Sequence Identity: 75% (196 aa)

FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDT
|||||||||||||||||||||||.|||||||||||.||||||||||||||.|.|..||.||||||||||||||||||.||||||||||||||||.|||||
FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQKMEHPFLVNLWYSFQDEEDMFMVCDLLLGGDLRYHLQQNVHFSEDT

VRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGW
|.||||||..||.||. .||||||.|||||||||.||.|.|||||||..||..|||...|||||||||||........|||..|||||.||.|||.||||
VKLYICEMCMALEYLQEMHIIHRDIKPDNILLDEHGHVHITDFNIATMLKDNQRATSMSGTKPYMAPEIFQCYMDECKGYSYPVDWWSLGVCAYEMLRGW

RPYDIHSSNAVESLVQLFSTVSVQYVPTWSKEMVALLRKLLTVNPEHRLSSLQDVQAAPAL
|||.|||....|.....|||.||.|...|..|||.||||||||.||||.|||||.|..|..
RPYHIHSNTPIEEIYHMFSTNSVHYPSHWCQEMVDLLRKLLTVDPEHRISSLQDIQKHPYM
Kinase YANK3.AA AGC 93-353 25 1.3e-139 363.39 In-house 1-395 (395) Show / Hide 
Range on Protein: 93-353
Range on HMM: 1-395/395
Sequence Identity: 25% (103 aa)

FQILRAIGKGSFGKVCIVQKR------DTEKMYAMKYMNKQQ-CIERD--EVRNVFRE------------LEILQEIE----------HVFLVN-LWYSF
|..|. |||||||||. |.|.      ||.|.|||| ..|.   ....  .|... .|             .||...           | |.|. |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDEED--MFMVVDLLL---------GG-DLRYHLQ---QNVQFSEDTVRLYICE-------MALALDYLRG-QHIIHRD-VKPDNILLDERGHAHLTDFN
||..    ..| ...          || .| .|||   ..  |.|...| |..|       ..|||.||   ..||||| .||.||||||.|| .|||| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IATIIKDGE---------------------------------------------------RATALAG--TKPYMAPEIFHSFVNGGTGYSFEVDWWS--V
 ........                                                   |.. . |  |  ||||||.         |....||||  .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---------YGKACDWWSFGL

GVMAYELLRGWRPYDIHSSN-------AVESLVQLFS------TVSVQYV----------PTWSKEMVALLRKLLTVNPEHRLSS---------LQDVQA
|.. ||.| |. |.  .. .         . . |.        .  |..           . .|.| . |..|||...||.|| .          .....
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

APAL
 |  
HPWF
Kinase YANK3.AA S_TKc 93-353 30 3.9e-84 286.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 93-353
Range on HMM: 1-231/231
Sequence Identity: 30% (85 aa)

FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLG--GDLRYHLQQNVQ---
..||| ||||.||||. .....| . .|.| ..          ... ||..||..  | ..|.| ..||| ....|| ... |  |||. .....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSF-EVDWWSVGV
   |.| ..| |......||.|.  ..|||||.||.||||||  |  ..|| .|...      | . ||  |||||..        ||.. ..||||.|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGC

MAYELLRGWRPYDIHSSNAVESLVQLFSTVSVQYVPTWSKEMVALLRKLLTVNPEHRLSSLQDVQ------AAPAL
. ||.| |  |..         . ..|  .        |.|.  ..||.|...||.|..  .  |      . | .
ILYEMLCGYPPFP--------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YANK3.AA SGK 93-295 37 5.6e-79 243.44 In-house 1-225 (283) Show / Hide 
Range on Protein: 93-295
Range on HMM: 1-225/283
Sequence Identity: 37% (86 aa)

FQILRAIGKGSFGKVCIVQKRDT------------------EKMYAMKYMNKQQCI-------ERDEVRNVFREL-EILQEIEHVFLVNLWYSFQDEEDM
|..|  |||||||||  |.. |.                  .|.||||  .||. |        . |....  |   ||. . | |.||| |.|| ..  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIAT-IIKDGERATALAGTKPYMAPEIFHSF
..| | . ||.. ||||    |.|| .| |  | ..||.||  | ||.|| ||.|||||  ||. ||||  .   ||. .  .  .||  |.|||. .  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLR--

VNGGTGYSFEVDWWSVGVMAYELLRGWRPY
   . ... .||||. |   ||.. |  |.
---KQPHDRTVDWWCLGCVLYEMMYGLPPF
Kinase YANK3.AA Akt 93-295 43 2.8e-74 236.84 In-house 1-203 (264) Show / Hide 
Range on Protein: 93-295
Range on HMM: 1-203/264
Sequence Identity: 43% (91 aa)

FQILRAIGKGSFGKVCIVQKRDTEKMY-AMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSED
|..|. .||||||||  |.| ||.|.| |||   |...|....|.... |  ||| . | |.||| ||||...  ..| |   ||.| ||||.   ||||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

TVRLYICEMALALDYLRGQHIIHRD-VKPDNILLDERGHAHLTDFNIAT-I-IKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWS-VGVMAYE
. | |..|. ||...|  . || ||  || |||.|. ||  ||||  .  . |||..... . ||  |.||||       |.|..  ||||. .|.  ||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILN-----GNGHTKAVDWWGSLGCVMYE

LLRGWRPY
.. |. |.
MMCGRPPF
Kinase YANK3.AA Pkinase 93-353 25 3.8e-68 237.5 Pfam 1-293 (293) Show / Hide 
Range on Protein: 93-353
Range on HMM: 1-293/293
Sequence Identity: 25% (77 aa)

FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVF-RELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGG----DLRYHLQ--QN
..|.| ||.||||.|.. ....|.|..|.| ..|.   .  .....  .|..|.... | . | |...|.|. .. || ... ||    ||  ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VQF--SEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHA----HLTDFNIATI--IKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVD
  |  ||.... |. ... .|.|.  . |||||.||.|||.|..||     ...|| .|    .  .. .| ..|| .|||||.    ..||..|. .||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV----IRGGQYYGPKVD

WWSVGVMAYELLRGWRPYDIH----SSNAVESLVQLFSTVSVQYVPTWS---------------------KEMVALLRKLLTVNPEHRLSSLQDVQAAPA
.||.|.. ||.| |  |.. |    . .    ....     . .   |.                     .|.  .....|...|. |..  ...   | 
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-AEQILQHPW

L
.
F
Kinase YANK3.AA RSK 96-353 32 3.1e-67 229.7 In-house 1-278 (278) Show / Hide 
Range on Protein: 96-353
Range on HMM: 1-278/278
Sequence Identity: 32% (91 aa)

LRAIGKGSFGKVCIVQKR---DTEKMYAMKYMNKQQCIERDE-VRNVFRELEILQEIE-HVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQ---
|.  |.|..||| ...|    ||.. ||||  .|   . |.  .| ...| .||.... | |.|.| |.||.|.  ... ... ||.| .|||. ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDE---RGHAHLTDFNIATI--IKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVG
||||... |. | .||...|  |.||||| ||.|||.|.   .||  ||||  . .  .......    .|  |||||.      .. |..  .|||| |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLG

VMAYELLRGWRPYDI-HSSNAVESLVQLFSTV-SVQYV--PTWSKEMVALLRKLLTVNPEHRLSS----LQDVQAAPAL
|  ||.| | .|.    ..|. | . .  .   |.     .. |.|.  |.||.|...|. ||..    ...... | .
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase YANK3.AA RSK-Unclassified 93-343 34 6.9e-66 205.76 In-house 1-269 (283) Show / Hide 
Range on Protein: 93-343
Range on HMM: 1-269/283
Sequence Identity: 34% (94 aa)

FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQ--QNVQFSE
|   | ||.|.||||  |.|.||...|||| ..|.. | .  .. |  | .|.   .| | | | .||| .  .... .   |||.  |||     .|.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

DTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFN--IAT--------------------IIKDGERATALAGTKPYMAPEIFHSFVNG
| || |. |  .|| ||  . .| || |||||.|.  ||. ||||   |                      |. .| |.    ||  |.|||.       
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIR-----

GTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFSTVSVQYVPTWSKEMVALLRKLLTVNPEHRLSS
. |    ||||  |.. ||.| |  ||    .| . . . .   |..      |..   |..|||. ||  || .
RCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNI-EKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGC
Kinase YANK3.AA AktR 93-341 36 2.8e-63 216.55 In-house 1-252 (268) Show / Hide 
Range on Protein: 93-341
Range on HMM: 1-252/268
Sequence Identity: 36% (94 aa)

FQILRAIGKGSFGKVCIVQKR-DTEKMYAMKYMNKQQCIERDEVRNVFRELEILQ-EIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSE
|.... .||| ||||  |||. |. |.||||   |.  |||   . . .|  |.. .. | |.|.| |.||..|  | . .   ||.| .||... .|||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DTVRLYICEMALALDYLRGQ-HIIHRDVKPDNILLDERGHAHLTDFNIAT--IIK-DGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAY
...| |.... |||.||  . .|| || ||.|||||| ||  .|||  .   ... . |.|. . ||  |||||.         |. . ||||..|.  |
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKK----KGHNKSVDWWAFGIFIY

ELLRGWRPYDIHSSNAVESLVQLFST-VSVQYVPTWSKEMVALLR-KLLTVNPEHRL
|.. |  | . |...  . . ..... ....| .  |..   |.  |||  ||..||
EMVTGCPPFY-HKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRL
Kinase YANK3.AA Ciliate-E2 93-353 20 7.9e-62 211.02 In-house 1-365 (365) Show / Hide 
Range on Protein: 93-353
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

FQILRAIGKGSFGKVCIVQKRDTEKM-----------------------YAMKYMNKQQCIERDEVRNVFRELE----------ILQEIEHVFLVNLWYS
. ... ||.|.||.|. .... . |.                       ||||.|.|.| ..   . ...||..          ||... | ..... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DEEDMFMVVDLLLGGDLRYHLQQN-----------VQFSEDTVRLYICEMAL---------------ALDYLRGQH-IIHRDVKPDNILLDERGHA
||  |.. ...| ... ||||......|            .|.|  .. .. . .                || ||  .. ||||| ||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

HLTDFNIATIIKDG--------------------------------ERATALAGTKPYMAPEIFHS-FVNG---GTGYSFEVDWWSVGVMAYELLRGWRP
 ..|| ......|                                 . .  ..|| .||||||. .   ..   ..||....|.||.||. ||.| | .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

YDIHSSNAVESLVQLFSTVSVQYVPT------------------WSKEMVALLRK----LLTVNPEHRLSSLQDVQAAPAL
.            |      ... .                   ||.|.  |..|    .| ..|| |... ...   | .
F-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase YANK3.AA Delta 93-353 35 1.3e-56 194.37 In-house 1-259 (259) Show / Hide 
Range on Protein: 93-353
Range on HMM: 1-259/259
Sequence Identity: 35% (96 aa)

FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQ-EIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSED
|.... .|||||||| ..  ....| ||.| . |.  .| |.|   . |  .|    || ||  |. .|| .| .| |.. | |||| ||.||  .|.| 
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

TVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIA--TIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELL
  | | ||. ..| .|  . || ||.| ||.|||  || .. || ..   .... ..| .  ||  |.|||| .     |  |.. ||||| ||. ||.|
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGE-KKASTFCGTPDYIAPEIIK-----GQKYNHSVDWWSFGVLMYEML

RGWRPYDIHSSNAVESLVQLFSTVSVQ--YVPTW-SKEMVALLRKLLTVNPEHRLSS----LQDVQAAPAL
 |  |.  .  .      .|| .. ..  . | | .||   .|.||.  .||.|| .      |... .  
IGQSPFHGEDED------ELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase YANK3.AA RSKR 93-289 35 5.8e-52 178.94 In-house 1-209 (296) Show / Hide 
Range on Protein: 93-289
Range on HMM: 1-209/296
Sequence Identity: 35% (76 aa)

FQILRAIGKGSFGKV-CIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIE---------------HVFLVNLWYSFQDEEDMFMVVDLLL-G
. |.. ..||||| | |.  . | .. .| | . |   |.|. || . .|  |   ..               | | . .  . |     .|.       
YRIDHLVAKGSFGVVYCVSDCHDQKQCFAIKMQKKRKIIQRNTVRQCKDEASIQRCCQDVTSDHSHFQRLLPHHPFIHRQYDTWQNRHHLYMMCEYPPCH

GDLRYHLQQNVQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFE
|||     |   |||. .||.| |.|.||.||    ||.||||. |||||..||. ||||  .   | | |.  . ||  ||||||     .|.. |.  
GDLYSLWRQRGHFSEMAIRLFIAELAMALCYLHNAGIIYRDVKMENILLDQWGHIKLTDFGLSKWMKQGARTYTICGTLQYMAPEI----LCGEP-YNHA

VDWWSVGVMAYELL
||||| ||... .|
VDWWSLGVIMCQML
Kinase YANK3.AA TyrKc 93-350 18 1.1e-13 -1.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 93-350
Range on HMM: 1-280/280
Sequence Identity: 18% (55 aa)

FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEI--EHVFLVNLWYSFQDE-------EDMFMVVDLLLGGDLRYHLQ
 . .. .| | ||.|.  . .    . | | ...        ..   ||..|. ..  .|  .|.|     ..       | ...|. .  .|||. .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QNVQ-FSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDG-------ERATALA--GTKP-----YMAPEIFHSFVNG
 .   .. ..   .    |   .||  ...||||    |.|..|....  .||  .  |.|.       .  ..    |.|       |||| .   .  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK--

GTGYSFEVDWWSVGVMAYELL-RGWRPYD------IHSSNAVESLVQLFSTVSVQY-----VPTWSKEMVALLRKLLTVNPEHRLSSLQDVQAA
   .... | || ||. .|.. .|  ||       .  . ..| . | .     ..      .. ..||  . ..    .|| | .  . ..  
---FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase YANK3.AA Pkinase_Tyr 93-235 21 1.8e-07 25.9 Pfam 1-155 (270) Show / Hide 
Range on Protein: 93-235
Range on HMM: 1-155/270
Sequence Identity: 21% (33 aa)

FQILRAIGKGSFGKVCIVQKR----DTEKMYAMKYMNKQQCIERD-EVRNVFRELEILQEI-EHVFLVNLWYSFQ-DEED--MFMVVDLLLGGDLRYHLQ
 .... .|.|.||.|.    .    .|.   | | . |... ...   .  .||..|. ..  |  .|.|      ..|   ...|. .  .|||. .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----NVQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDF
.    . ...  .   .  . | ...||  ...||||.   |.|..| ...  .||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDF
Kinase YANK3.AA RSKR 322-353 40 3e-07 22.01 In-house 265-296 (296) Show / Hide 
Range on Protein: 322-353
Range on HMM: 265-296/296
Sequence Identity: 40% (13 aa)

SKEMVALLRKLLTVNPEHRLSSLQDVQAAPAL
|.|.  |....|..|| ||| ||   |. | .
SHEFCDLMHRMLCQNPNHRLCSLHHLQHHPFF
Kinase YANK3.AA Akt 328-353 26 0.038456 2.55 In-house 235-264 (264) Show / Hide 
Range on Protein: 328-353
Range on HMM: 235-264/264
Sequence Identity: 26% (8 aa)

LLRKLLTVNPEHRLS----SLQDVQAAPAL
|...||. .|..||      .|.... | .
LISGLLNKDPKKRLGGGPNDAQEIKRHPWF