Gene ULK3 (Human)

ULK3

Species: Human
Alias: FLJ90566, ULK3, DKFZP434C131
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , iHOP , GeneCards
Annotation: Consensus chromosomal location: 15q24-q25,

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
ULK3.NA RNA Sugen Kinome 2769 None Fasta, JSON
ULK3.AA Protein Sugen Kinome 472 None Fasta, JSON
ULK3.kin_dom Protein Kinase Domain Sugen Kinome 257 None Fasta, JSON

Protein domain

Protein domains of ULK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ULK3.AA ULK 14-270 33 7e-119 401.25 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-324/324
Sequence Identity: 33% (108 aa)

FILTERLGSGTYA-TVYKAY-AKKDT-REVVAIKCVAKKSLNKASVE--------NLLTEIEILKGIR---HPH--IVQLKDFQWDS--DNIYLIMEFCA
..| ..||.|... .|||..  |..|  ..||.|.. ||..|| . |        .|  ||.|.| .    ||.  ||.|.|....|  .|||.|||.| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLSRFIHTRRILPEKV----------ARVFMQQLASALQFLHERNISHLDLKPQNILLSSLE----------KPHLKLADFGFAQHMSPWDEKHVLR-
||||. .|.... ||| .          |. |..|.......||..|| | |.||||||..             ...||.||||||.|   ...   .. 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSPLYMAPEMVC----QRQYD-ARVDLWSMGVILYEALFGQPPFASRSFSELE-------------EKIRSNRVIELP---LRPLLSRDCR
         |.||||||. .     | .|. . .|.||.|.|.|| |.|..|| |. |....             . .  |. |. |     | .| .|.
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLLQRLLERDPSRRISFQDFFAHPWV
||..|.|..|.. |||....|.|||.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase ULK3.AA ULK 14-270 33 8.4e-114 384.38 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-329/329
Sequence Identity: 33% (109 aa)

FILTERLGSGTYATVYKAYAKKDT---REVVAIKCVAKKSLNKASVEN--------LLTEIEILKGIR--------HPHIVQLKDFQWDS--DNIYLIME
..| ..||.|....|||.. ||.     |.||.| . |...|. . |.        |  ||.|.| .         ||.||.|.|....|  .|||.|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCAGGDLSRFIHTRRILPEKV----------ARVFMQQLASALQFLHERNISHLDLKPQNILLSSLE----------KPHLKLADFGFAQHMSPW-----
.| ||||. .|.... |||..          |. |..|.......||..|| | |.||||||..             ...||.||||||.|.. .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-DEKHV----LRGSPLYMAPEMVC----QRQYD-ARVDLWSMGVILYEALFGQPPFASRSFSELE-EKIRSNRVI---------ELPLR-------PLLS
     |    |.|.||||||. .     | .|. . .|.||.|.|.|| |.|.||| .  |...   .|.... .           ||.       | .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

RDCRDLLQRLLERDPSRRISFQDFFAHPWV
 .|.||..|.|..|.. |||....|.|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase ULK3.AA S_TKc 14-270 34 3.4e-100 340.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAG--GDLSRFIHTRRI---
. . . .|.|....|||.. || | ..||||..          |... ||.|||  .||.||.|.|.  | |..|..||.| |  ||| ..|. |.    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDA-RVDLWSMGVILY
   .|| .|| .|.|...||...|...| | ||||.||||..    |.|..|||.| ..      . . |.| |||||..   .|.  ..| || |.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFA-------HPWV
| | |.|||      .. .||.             |....|.....|..||..|..  . ..       |||.
EMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ULK3.AA CAMK 19-270 22 5.3e-93 299.98 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-425/425
Sequence Identity: 22% (96 aa)

RLGSGTYATVYKAYAKKDTR-----------EVVAIKCVAKKSLN--------------------------KASVENLLTEIEILKG-------IRHPHI
 ||.|....|.... |..|.           . |||| . || |                             . .|.. ||||.|        ..||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLKDFQWD-------------------SDNIYLIM---EFCAGG----DLSRFIHTR---------------RILPEKVARVFMQQLASALQFLHERNI
..| ..  |                    ...|..|   |.| ||    ||  .|  .               . ..|. || ...|..||....|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHLDLKPQNILLSSLEKP---------------HLKLADFGFAQHMSP------------------------WDEKHVLRGSPLYMA-PEMVCQ------
 |.|||| ||||.. ..                 .|..|||||... |                         .  .   |.| ||| ||.. .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RQYDARVDLWSMGVILYEALFGQPPFASR-------------SFSELEEKIRSNRV--IELPLRPL-------------------LSRDCRD
        . |.  .| ||.|||||  | | ||| .              . .|| |||.. .   .. .. |.                   .| .|.|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLQRLLERDPSRRISFQDFFAHPWV
|....|..||..|.. ..  .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase ULK3.AA AGC 14-270 23 5.3e-90 232.18 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-395/395
Sequence Identity: 23% (94 aa)

FILTERLGSGTYATVYKAYAKK-----DTREVVAIKCVAKKS----LNKASVENLLTE------------IEILKGIR----------HPHIVQ-LKDFQ
| .   .| |.. .|| .  |.     || .. |.|.. ||     ..|  ||. .||             .||. ..          || ||. |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

WDSDN--IYLIMEFCA--------GGDLSRFIHTR-R----ILPEKVARVFMQQ-------LASALQFLHE-RNISHLD-LKPQNILLSSLEKPHLKLAD
 | |.  .|..||..         ||..  |.| . |    ...|..|| .. .       ...||..||. ..| | | ||| |||| .    |.||.|
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED--GHIKLTD

FGFAQHMSPWDEK---------------------------------------------------HVLRG--SPLYMAPEMVCQRQYDARVDLWS--MGVI
||..  .   .||                                                   . . |  .| |||||..    |.  .| ||  .|..
FGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCL

LYEALFGQPPFASRS----------FSELEEKIRS-----NRVIELPLR--------PLLSRDCRDLLQRLLERDPSRRIS----------FQDFFAHPW
.|| |.|.||| . .            |. .||..     |  ...|          . .| ...||...||..||..|.           ...  .|||
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

V
 
F
Kinase ULK3.AA Pkinase 14-270 29 9.8e-87 299.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLT--EIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGG----DLSRFIH--T
. . ...|||....|||.. .|.|...||.|.. |.. ..   ....   ||.|.| ..||.||.|.|.  |.|.||..||.| ||    ||...|.   
YHIGRKIGSGSFGCVYKCH-HKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

RRIL--PEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHL----KLADFGFAQH--MSPWDEKHVLRGSPLYMAPEMVC-QRQYDARVDL
.. .  .|.... .| |....|...|...| | ||||.|||..  ...|.    |..|||.| .    .    ... |.| ||||| .  .. |. .|| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSMGVILYEALFGQPPFASR----SFSELEEKIRSNRVIELPLRPLLS---------------------RDCRDLLQRLLERDPSRRISFQDFFAHPWV
||.|.|||| |.|.||| ..    .  .  ..|. ..  .|.     .                     ..|.|.. ..|..||..|..... . |||.
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase ULK3.AA CAMKL 14-270 30 5e-82 261.55 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-297/297
Sequence Identity: 30% (91 aa)

FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLN-KASVEN------------LLTEIEILKGIR---HPHIVQLKDFQWDSDN------IYLIM
... . || |....|  |  .. |.| |||| . || .. .  ...            .  ||.|.| ..   ||.|..| .   ....      |||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCAGGD--LSRFI--HTRRI--LPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSP---WDEK--HVLRGSPLYM
| | ||.  |  .|  | .|   .||. || . .|. ||....|...| | |.|| ||||..  .  .|..||||. .. |   ....  .   ||| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEMVCQ--RQYD-ARVDLWSMGVILYEALFGQPPFASRS-------FSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWV
|||..    ..||   || ||.|||||  ..|. ||   .          .....      . |  . .| |||||....|...|..|.. ..   |||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase ULK3.AA Ciliate-E2 14-270 24 4e-78 265.87 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

FILTERLGSGTYATVYKAYAKKDTREV-----------------VAIKCVAKKSLNKASVENLLTEIEILKGIR----------------HPHIVQLKDF
... . .|.|....|||.  .|. ...                 |.|| .|.|...|  .|... || |.. |.                ||.|......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

QW--DSDNIYLIMEFCAGGDLSRFIHTRRILP-----------EKVARVFMQQLAS---------------ALQFLHERN-ISHLDLKPQNILLSSLEKP
    | .||||.||.| ||||  .|  ...             || .. .|.|...               ||..||..| | | |.||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

HLKLADFGFAQ-------------HMSPWDEKHV--------------------LRGSPLYMAPEMVC---------QRQYDARVDLWSMGVILYEALFG
 .|..|||...             ..  . . ..                    . |.| |||||..          | .||  .|.||.|||||| |||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

QPPFASRSFSELEEKIRSNRVIELP----------------LRPLLSRDCRDLLQR----LLERDPSRRIS-FQDFFAHPWV
.|||         ...  .  |..|                    .| .| ||...    .|..||. ||. ... . ||| 
KPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase ULK3.AA MARK 14-270 36 6e-72 234.51 In-house 1-262 (262) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-262/262
Sequence Identity: 36% (96 aa)

FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNK-ASVENLLTEIEILKGIRHPHIVQLKDFQW--DSDN-IYLIMEFCAGGDLSRFIHTR--R
. .   .| |.||.|..|  |. |.. |||| . |..||.  . .|.  ||||.| . ||.|..| .     .. . |||||| . ||.|  .|  .  .
YKMLKTIGHGSYAKVKLACHKH-TGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

ILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYD-ARVDLWSMGVILYEA
 |.|. ||.. .|. ||....|..|| | |.||.|||. .  .   |..||||. .  |        |.| |||||.. .. ||   || ||.||.||  
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LFGQPPFASRS--FSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWV
. |. ||   .  . ||..||.. .    | .  .|..||.|.||||  .|..|.. ..   |||.
VCGYFPFDGDTQDYKELYKKILRGKYD-IPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase ULK3.AA STE 14-270 21 8.5e-70 238.19 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-359/359
Sequence Identity: 21% (80 aa)

FILTERLGSGTYATVYKAYAKK-----DTREV---------VAIKCVAKKSLNK---------------ASVENLLTEIEILKGIR--HPHIVQLKDFQW
. . |..|.|.. |||||. .|     .| ||         .||| . ... |.                 ....| ||.|.|  .  ||.||.  .   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DS-------DNIYLIMEFCAGGDLSRFIHTR--------------RILPEKVARVFMQQLASA-LQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGF
.        |.....||...|| |. .|...                .||.. ... .|.  . |..||. .| | |.||.||||        ||.|||.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------VKLCDFGV

AQHMSP----------------WDEKH-VLRGSPLYMAPEMVCQ------RQYDARVDLWSMGVILYEALFGQPPFAS-RSFSELEEKIRSNRVIE----
.  ...                 ..|   . |.| .||||.. |       .||...| || |  . | . |.||..    .. . ........ .    
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----LPLRPLLS----------------------RDCRDLLQRLLERDPSRRISFQDFFA--HPWV
      |  || .                       ...| ... |..||. | . ..     ||..
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase ULK3.AA Ciliate-E2-Unclassified 14-270 24 3.9e-69 236.01 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

FILTERLGSGTYATVYKAYAKKDTREV------VAIKCVAKKSLNKASVENLLTEIEILKG----------------IRHPHIVQLKDFQW--DSDNIYL
... . .|.| ...|||.. ||.  ..        |. ...|. ..   | .. ..|. .                 . |||.. .|.| .  | .|||.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEFCAGGDLSRFI-----------------HTRRILPEKVAR-----VFMQQLASALQFLHERN-ISHLDLKPQNILLSSLE-KPHLKLADFGFAQ---
.||.| ||||. .|                 ..|.|..|. |.      .. |. ..|..||. | | | |.||.|||...   . ..|..|||..    
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-----------HMSPWDEKHV--LRGSPLYM----APEMVCQRQYDAR----VDLWSMGVILYEALFGQPPFASRSFSE---------------LEEKIR
            |. |....     |.| ||    |||. .. .|| .    .| ||.|||||| |||..|| ...  .                 ... 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

SNRVIELPLRPL------LSRDCRDLLQ----RLLERDPSRRISFQDFFAHPWV
 .. |. |  |       .|  . |...    ..|. .|. ||.|.. . ||| 
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase ULK3.AA RSK 16-270 29 3e-65 223.07 In-house 1-278 (278) Show / Hide 
Range on Protein: 16-270
Range on HMM: 1-278/278
Sequence Identity: 29% (83 aa)

LTER--LGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKAS--VENLLTEIEILKGIR-HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRI--
| .   .| | . .. .    .||. . | | . |. . ..   ..  .||..||. .. || ||.|..   . . .|||||.| ||.| . . ....  
LKVLGQGGYGKVFLC-RKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-LPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLE-KPHLKLADFGFAQHMSPWDEK--HVLRGSPLYMAPEMVC---QRQ-YDARVDLWSMG
 . |. |.. | ....|...||.. | | |||| |||. . .   |.|| ||||.  ... ...  .  ...  ||||||.    |.  .|. .|.|| |
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VILYEALFGQPPFAS---RSFSELEEKIRSNRVIELPLR--PLLSRDCRDLLQRLLERDPSRRIS-----FQDFFAHPWV
|..|| |.|.|||..    . .|. ..|.... . |..   . ||....||....|.|||..|..      ..  .||| 
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK-FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase ULK3.AA Pkinase_Tyr 14-159 27 1.1e-29 101.2 Pfam 1-156 (270) Show / Hide 
Range on Protein: 14-159
Range on HMM: 1-156/270
Sequence Identity: 27% (43 aa)

FILTERLGSGTYATVYKAYAK---KDTREVVAIKCVAKKSLNKAS--VENLLTEIEILKGI-RHPHIVQLKDFQW-DSDN--IYLIMEFCAGGDLSRFIH
 .. . ||.| . .|||...|   ..|.  ||.|.. | .  .     | .. |..|.| . .||.||.|      ...   ||..||....|||  . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----RRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFG
.    .. |. |    . .| |.....|...|. | ||   |.|...  . . | .|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFG
Kinase ULK3.AA TyrKc 14-275 22 2.1e-26 94.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGI--RHPHIVQLKDFQWDS-------DNIYLIMEFCAGGDLSRFIH
  | . ||.| . .|||. .|    . ||.|.. . .     .| .. |..|.. .  .||.||.|     ..       . ....||....|||  ...
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TRRI-LPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPW-------DEKHV-----LRG-SPL-YMAPEMVCQRQ
 .|  |. |    |. | |.  ..||..|. | ||   |.|...    . | .||| .             | ...      ..  |.  ||||    . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDARVDLWSMGVILYEAL-FGQPPFAS-----RSFSELEEKIRSNRVIELPLRPL------LSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHM
.    | || || ..| . .||.|         | .|. |.... .  . |  ..       . .  .. ..  ..||. | .|..         | .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HECF
MIT ULK3.AA MIT 280-348 32 6.7e-27 96.62 Pfam 1-71 (71) Show / Hide 
Range on Protein: 280-348
Range on HMM: 1-71/71
Sequence Identity: 32% (23 aa)

SLGRATALVVQAVKKDQ-EGDSAAALSLYCKALDFFVPALHYEVDAQRKEA-IKAKVGQYVSRAEELKAIV
.| .|  || .||..|. .|. ..|. .|..|.. |..|..|| .....|| ...|. .|..|||..|...
YLQKAIELVKKAVEADEDAGNYEEAIQCYQEAIEYFMQAIKYEPNPKWREARLRQKMQEYMDRAEQIKEHL
MIT ULK3.AA MIT 277-354 30 2.9e-18 67.92 SMART 1-81 (81) Show / Hide 
Range on Protein: 277-354
Range on HMM: 1-81/81
Sequence Identity: 30% (25 aa)

SGESLGRATALVVQAVKKDQ--EGDSAAALSLYCKALDFFVPALHYE-VDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQA
    . .|  .. |||| |.  .||...|. .|.|..| .. ...||  |  |..||.||. .|  |.||.|. . .  ..
QRDYYQKAIEYITQAVKADEDEWGDYEQAIEHYQKGIDYLMQGIKYEKPDEKRRHAIWAKCREYLDRMEEIKNCHDWRLCP
MIT ULK3.AA MIT 375-444 30 4.2e-16 59.01 Pfam 1-71 (71) Show / Hide 
Range on Protein: 375-444
Range on HMM: 1-71/71
Sequence Identity: 30% (22 aa)

RLLAALEVASAAMAKEE-AAGGEQDALDLYQHSLGELLLLLAAEPPGRRREL-LHTEVQNLMARAEYLKEQV
 | .|.|... |. ..| |   |. |...||....... ....||  ..||. |.. .|. |.|||..||..
YLQKAIELVKKAVEADEDAGNYEE-AIQCYQEAIEYFMQAIKYEPNPKWREARLRQKMQEYMDRAEQIKEHL
MIT ULK3.AA MIT 372-450 20 8.5e-07 29.83 SMART 1-81 (81) Show / Hide 
Range on Protein: 372-450
Range on HMM: 1-81/81
Sequence Identity: 20% (17 aa)

DKPRLLAALEVASAAMAKEEA-AGGEQDALDLYQHSLGELLLLLAAE-PPGRRRELLHTEVQNLMARAEYLKEQVKMRESR
 .. . .| | .. | . .|  .|  ..|...||. .. |.  .. | |.  ||. .   .. .. |.|..|.... |.  
QRDYYQKAIEYITQAVKADEDEWGDYEQAIEHYQKGIDYLMQGIKYEKPDEKRRHAIWAKCREYLDRMEEIKNCHDWRLCP