Gene TAO3 (Human)

TAO3

Species: Human
Alias: DKFZp666H245, JIK, FLJ31808, MAP3K18, TAO3, DPK, TAOK3
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 12q24.33,

Classification

Group: STE
Family: STE20
Subfamily: TAO

Sequence

Name Sequence Type Origin Length Description Download
TAO3.NA RNA Sugen Kinome 4399 None Fasta, JSON
TAO3.AA Protein Sugen Kinome 898 None Fasta, JSON
TAO3.kin_dom Protein Kinase Domain Sugen Kinome 254 None Fasta, JSON

Protein domain

Protein domains of TAO3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TAO3.AA TAO 24-277 84 1.2e-201 664.83 In-house 1-254 (254) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-254/254
Sequence Identity: 84% (215 aa)

FIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVE
| .|.|||||||||||||...||.||||||||||||||.|||||||.|||.||.|.||||.||||||||.|||.|||||||||||||.|.|||||.||||
FQDLREIGHGSFGAVYFARDKHTEEVVAIKKMSYSGKQSHEKWQDIIKEVRFLQQVKHPNCIEYKGCYLREHTCWLVMEYCLGSASDILDVHKKPMQEVE

IAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFN
||||.||||.||.|||||..||||||||||||||.|||||||||||||..||||||||||||||||||||||||||||||.|||||||||||||||||||
IAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFN

MNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
|||||||||||||||||||.|||.|.|..|||.||||.|||||...|.|||.||
MNAMSALYHIAQNDSPTLQQNEWSDCFHQFVDKCLQKMPQERPSAEECLRHEFV
Kinase TAO3.AA STE20 24-277 47 1.1e-147 496.88 In-house 1-288 (288) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-288/288
Sequence Identity: 47% (137 aa)

FIGLHEIGHGSFGAVYFATNAHTSEV----VAIKKMSYSGK---QTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA----WLVMEYCLG-SASDL
.  |..||.||.|.||.|.. .| |.    ||||||... .   |  ..|.||.||. ...|.|||| ..| |.|||..|.    |.||||| | |..|.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ--DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDI

LE---VHKK-----PLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMAS--------PANSFVGTPYWMAPEVILAMD
..   ...|     |..|..||.|....| ||.||||.  |||||||.|||||| |.||||||| .|.. .        . |.|||||||||||||. |.
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

--EGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIA--QNDSPTLQ---SNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
  ...|| |.||||||||.||.||..||.|.|..|.|...|.  ||..|||.   .. |...|. ||| |||| |..|||. .||.| |.
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase TAO3.AA STE 24-277 33 5.8e-125 421.45 In-house 1-359 (359) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-359/359
Sequence Identity: 33% (124 aa)

FIGLHEIGHGSFGAVYFATNA------HTSEV---------VAIKKMSYSGKQT--------------HEKWQDILKEVKFLRQLK--HPNTIEYKGCYL
. |. .||.|.|| || | |       .| ||         .|||.|... ...              ||..|.||||.|......  ||| ..| |||.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KE-------HTAWLVMEYCL-GSASDLLE---VHKKPLQ----------EVEIAAITHGALHG-LAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSAS
||       .. |..|||.  ||..|...    ..|||.          | .||.|..  |.| |.|||||  ||||||..||||     |||.||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

MASP--------------------ANSFVGTPYWMAPEVILAMDEG---QYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQN-----------
  ..                     |.||||| |||||||. ...|   .|| |.||||||.|.||.|. |||...|. |.|...|..|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----DSPTLQSN------------------EWTDSFRRFVDYCLQKIPQERPTSAELLR--HDFV
    ..|.|...                  .|...|. |.. |||| |..|||. .||.  | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TAO3.AA MST 24-277 43 5.5e-106 337.89 In-house 1-254 (254) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-254/254
Sequence Identity: 43% (114 aa)

FIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYL--KEHTAWLVMEYC-LGSASDLLEVHKKPLQ
|  .  .| ||.| || |..  |...||||...     . |  |.|.||  .. | | ..   | | |.  |. . |.|||||  ||..|.    ...| 
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVP-----VNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLN

EVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASP----ANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAE
|..||.|  ..| ||.|||.   |||||||||||| . |  |||||| ..  .     .|...|||||||||||    |  || |.||||||||.||.||
EQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVI---QEIKYDCKADIWSLGITAIEMAE

RKPPLFNMNAMSALYHIAQNDSPTLQS-NEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
 .||...  .|.|.  | |. .||..   .| . | .||  |||| |..|.|. .|| |.|.
GMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase TAO3.AA YSK 24-277 44 1.1e-101 306.94 In-house 1-257 (257) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-257/257
Sequence Identity: 44% (115 aa)

FIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCL-GSASDLLEV-HKKPLQE
|  .  || |||| || . . .| .|||||       .  .   || .|. || |.. |.   | | |||    | .||||  ||..||.   .  ...|
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDL--EHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDE

VEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMAS----PANSFVGTPYWMAPEVILAMDE-GQYDGKVDIWSLGITCIELAE
  || | .  | || ||||   ||||||| |.||.| |.|||.||| |.         | |||||||||||||  . |  .|| |.|||||||| .|.| 
KYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVI--CQEVSYYDFKADIWSLGITAYEMAK

RKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
  ||.  . .| ..  |  |  |.|. ......|  ||. || | |..||.  ||| | |.
GEPPYCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase TAO3.AA S_TKc 24-277 28 2e-86 294.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

FIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLG---SASDLLEVHKKP--
.  | .||.|.|| || ... .| ..||||...          ..|..|.. |.. .||| . .....   .  ..||||| |   .  |... ....  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDG-KVDIWSLGITCIEL
   . | ... ...  . .|.|.|||  ||||.|  ||||.|  ..|..|||.|      ..|.|||..|||||.      .|.. |.|.||.|.. .|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEM

AERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLR-------HDFV
. ..||      | .....             ..... |.. |||| |..|||  |.|.       | ..
LCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TAO3.AA PAKA 24-277 39 1.1e-78 267.69 In-house 1-260 (260) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-260/260
Sequence Identity: 39% (104 aa)

FIGLHEIGHGSFGAVYFATNAHTSEV--VAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCL-GSASDLLEVHKK---
.  . .|| |. |.|| |||..| .   ||||.|     ..  | . |. | . ... ||.| . |   || ..  |.||||   |.  |...   .   
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNM---KNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQC

-PLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASP----ANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCI
 ...|  ||..    | || ..||.  ||||||  ||||   |.||..||| .   ..     |. ||||||||||||.     ||| ||||||||| .|
NYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRK---QYDEKVDIWSLGIMAI

ELAERKPPLFNMNAMSALYHIAQNDSPTLQSNE-WTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
|..|  ||  |..   |.| ||.|  | ... . |...|..|.| ||.. ...|... |||.| | 
EMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase TAO3.AA Pkinase 24-277 27 2.5e-76 264.67 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

FIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILK--EVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLG-----SASDLLE-VH
.  .  || |||| || ...  |...||.|..... .. ..|.|  ..  |.. .. |.||| .......  .   ..||||| |     . .|...   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KKPL--QEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQV----KLADFGSASM----ASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIW
....  .| |.  .    | ||.|.||.  ||||.|  |||. . |..    |..|||.|       | ...|.|||..||||||.  .   |. |||.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIR--GGQYYGPKVDMW

SLGITCIELAERKPPLFNM----NAMSALYHIAQNDSPTLQSNEW----------------------TDSFRRFVDYCLQKIPQERPTSAELLRHDFV
|.|....|.. ..||  .     | .. .. |... .| | ....                      ..... |...||.| |..||| ...| |...
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TAO3.AA KHS 24-277 41 2.1e-75 253.05 In-house 1-258 (258) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-258/258
Sequence Identity: 41% (108 aa)

FIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYC-LGSASDLLEVHKKPLQEV
.  |  .| | .| || | . ...|..|.| .     .  .  . | .|.  ... .||| . | | ||..   |..||||  ||  |. .|   ||.|.
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKM---EPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVT-GPLSEL

EIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMASPAN---SFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERK
 || ... .|.||.||||.  .|||||  |||||. |.||||||| || ..   .   ||.||||||||||     .| |.   |||..||| ||||| .
QIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQ

PPLFNMNAMSALYHIAQND--SPTLQS-NEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
||.|..  | ||. ... .   |.|.  . |...|  ||  .| | |. |||.  ||.| ||
PPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase TAO3.AA SLK 27-277 40 1.3e-74 251.11 In-house 4-259 (259) Show / Hide 
Range on Protein: 27-277
Range on HMM: 4-259/259
Sequence Identity: 40% (104 aa)

LHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVH-KKPLQEVEIA
. |.| | || || | .  .. . | | .     .  |. .| . |.  | ..|||| ..  . |  ..  |...|.| | | | . |  ..||.|  |.
IGELGDGAFGKVYKAQHKEQKVFAAAKMIEI---KDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

AITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMASPAN---SFVGTPYWMAPEVIL--AMDEGQYDGKVDIWSLGITCIELAERKP
 . .  . .| .|||. .||||.||||||.|  |.|.||||| ||   .. .   .|.||||||||||..   . .  || |.|||||||| ||.|.  |
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PLFNMNAMSALYHIAQNDSPTL-QSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
|  .|| |  |  |.. . ||| |  .|. .|. |.  ||.| || |.|.|.|..| .|
PHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase TAO3.AA PAKL 24-277 41 1.3e-71 244.25 In-house 1-256 (256) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-256/256
Sequence Identity: 41% (109 aa)

FIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKE-HTAWLVMEYC-LGSASDLLEVHKKPLQE
|.     | ||.|.|| |.   |  . ||| ..   | . |  .|| ||.  |   | || . | |    .    |  |.|| |||  |..|.  | |.|
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEI--KESNE-IKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNE

VEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-----SASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAE
 .|. |.  .| || ||||   ||||||| ||||.| .|||.||||       .    ||. .|||||||||.|.  .   |. |.|||||||| ||.|.
KQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQN---YNNKCDIWSLGITAIEMAD

RKPPLFNMNAMSALYHIAQNDSPTLQS-NEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
  ||.  |. | |.| |     ||.     |   |  |.. |..| | .|.   .|| |.| 
GFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase TAO3.AA Ste20-DD1 24-277 40 7.6e-71 241.68 In-house 1-268 (268) Show / Hide 
Range on Protein: 24-277
Range on HMM: 1-268/268
Sequence Identity: 40% (109 aa)

FIGLHEIGHGSFGAVYFA-------TNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQ-LKHPNTIEYKGCYLKEHTAWLVMEYCL-GSASDLLEV
|  .  || |||| |           |    .|.|.| .   .    |      ||.  |.  .. |  ..|.|||.||     |||||  ||  | .. 
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDV-EENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQM

HKKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMAS----PANSFVGTPYWMAPEVILA--MDEGQYDGKVDIWSLG
  | | | .||||  .   || ||||   .||||||||.|. . || ||||||    |       |  .| ||||.||.|      .| || | ||||||
CSKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQG-YDQKADIWSLG

ITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQ-SNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV
|| ||.|| |||.||.|     . |     |||.   .|   |  |.  || . |  ||   .|| | |.
ITAIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase TAO3.AA TyrKc 24-276 23 6e-29 103.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-276
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMS-YSGKQTHEKWQDILKEVKFLRQL--KHPNTIEYKGCYLKE-------HTAWLVMEYC-LGSASDLL
   ....|.| || || .|     . ||.|..  ..        .|...| . ...|  .||| .   |. ...       .  ..||||. .|.  | |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

EVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPA-------NSFV-----GTP-----YWMAPEVILAMDE
  |.. |.  .   . . .  | .||||. .||||. | |.|..|...|| .||| .                .     |.       |||||.|   ..
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NY

GQYDGKVDIWSLGITCIELAER-KPPLFN-----MNAMSALYHIAQNDSPTLQSN-------EWTDSFRRFVDYCLQKIPQERPTSAELLRHDF
| .  | |.|| |... |.  . ..|  .     |..  .. .. | . .    |       . .|   .    | .  | .||| .|. ...|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase TAO3.AA Pkinase_Tyr 24-167 31 3.5e-24 82.52 Pfam 1-156 (270) Show / Hide 
Range on Protein: 24-167
Range on HMM: 1-156/270
Sequence Identity: 31% (50 aa)

FIGLHEIGHGSFGAVYFATNA----HTSEVVAIKKM--SYSGKQTHEKWQDILKEVKFLRQL-KHPNTIEYKGCYL-KEHT--AWLVMEYC-LGSASDLL
 . ....|.|.|| || .|       |   ||.|..  ... .|   ...| ..|.| ..|| .||| . . |. . ..     ..||||. .|.  | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN--CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

EVH---KKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG
  |   |.||   ..  . .    |..||.|. .||||. | |.|.||...|| .|||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase TAO3.AA Pkinase_Tyr 184-214 38 0.010327 9.81 Pfam 180-207 (270) Show / Hide 
Range on Protein: 184-214
Range on HMM: 180-207/270
Sequence Identity: 38% (12 aa)

WMAPEVILAMDEGQYDGKVDIWSLGITCIEL
|||||.|  .    .  | |.|| |... |.
WMAPECINYGK---FTTKSDVWSFGVLMWEI