Gene STK33 (Human)

STK33

Species: Human
Alias: STK33
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 11p15.4,

Classification

Group: CAMK
Family: STK33

Sequence

Name Sequence Type Origin Length Description Download
STK33.NA RNA Sugen Kinome 2707 None Fasta, JSON
STK33.AA Protein Sugen Kinome 514 None Fasta, JSON
STK33.kin_dom Protein Kinase Domain Sugen Kinome 266 None Fasta, JSON

Protein domain

Protein domains of STK33.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase STK33.AA CAMK-Unique 116-381 36 3e-159 529.51 In-house 1-363 (363) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-363/363
Sequence Identity: 36% (133 aa)

YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKL------------------LEREVNILKSVKHEHIIHLEQV----FETPK-------
|...||.|.|.||.|.|..|.||..|||.|.|.|...|... |.                  |.||..|.|.|.|..||.|...    |...|       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------KMYLVMELCEDGELKEILDR--------------------KGHFSE--NETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLID----
        .||.|||.|..|.|......                    .|||||  ..|..|.|.|.||.||.|..||||||||||||||..|..|    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

---DNNEINLNIKVTDFGLAVKKQ-SRSEAMLQATCGTPIYMAP--------------EVISAHDYSQQC----DIWSIGVVMYMLLRGEPPFLASSEE-
   .....|..||..||||..... .....|.|..||||.||||              ||| ...|.|||    ||||.||.||..| |.||| ...|. 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------KLFELIRKGEL-HFENAVWNS---ISDCAKSVLKQLMKVDPAHRITAKELLDNQWL
       ..|| |.||.. .|.. .|..   ||..||...|..|.|||.||..|||||..||.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase STK33.AA CAMK 121-381 25 3.7e-113 366.1 In-house 1-425 (425) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-425/425
Sequence Identity: 25% (109 aa)

ILGKGSFGIVIEATDKETE------------TKWAIKKVNKEKAG--------------------------SSAVKLLEREVNILKS-------VKHEHI
.||.||||.| ....|.|             .|.||| ..|.|.                            .  | ..||..|.|.       ..|..|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IHLEQVFE------------TPKK--------MYLVM---ELCEDGEL----------K----------EILDRKGHFSENETRWIIQSLASAIAYLHNN
|.| .|.|            | .|        ||.||   |.|. |||          .          .|. ..|.|.| |.| ... ..||..|.|..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

DIVHRDLKLENIMVKSSLIDDNN--------EINLNIKVTDFGLAVKKQSRS----------------------EAMLQATCGTPIYMA-PEVISA----
.|||||||.|||.. ..  |...        . | |||..|||.| |... .                        ...  |||| ||| |||..     
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------HDYSQQCDIWSIGVVMYMLLRGEPPFLAS-------------SEEKLFELIRKGELHFENAV------------WNSISDC--------A
            |...||.||.||..|..| |.||| ..             ....||| |.||. .|.               |..|||         .
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KSVLKQLMKVDPAHRITAKELLDNQWL
|. ......||| .|.|... |. .|.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase STK33.AA CAMK1 116-381 36 1.6e-108 316.62 In-house 1-276 (276) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-276/276
Sequence Identity: 36% (104 aa)

YTFGRILGKGSFGIVIEATDKET---ETKWAIKKVN-KEKAGSSAV---KLLEREVNILKSV---KHEHIIHLEQVFETPKKMYLVMELCEDGELKEILD
| || ..|.|.|..| ..|.|||   . ..|||  . |.    . .   ..||.|..|.|.|   .|..|| .. ..|.... ||||||.  ||| .   
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

RKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIK--VTDFGLAVKKQSRSEA-MLQATCGTPIYMAPEVISA---HD
 ||...|.. | |.. ..||. |.| ..||||||| ||.  ..      .. .  ||  . ||||.  |.  ..  ...  |||| |.||||.       
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYD------KDEDSKIKRSIADFGLS--KIFDHDENLMKTACGTPGYVAPEVLECKKDKP

YSQQCDIWSIGVVMYMLLRGEPPFLASS-EEKLFELIRKGELHFENAVWNSISDC-AKSVLKQLMKVDPAHRITAKELLDNQWL
|.. ||.|||||. | || | ||| ... ...|||.| |.|. | .  |..|||  ||  .|....|||  |.|... |.  |.
YDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase STK33.AA Ciliate-E2a 116-381 36 7.1e-101 297.66 In-house 1-275 (275) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-275/275
Sequence Identity: 36% (101 aa)

YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSA--VKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELK-EILDRKGHFSE
| | ...|||.|| |  |. |.|  . |.||..| |.  .    . ...|.||.....| .|| |  |.|. .  |||||.|| |||. .|   |  |.|
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

-NETRWIIQSLAS-AIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHD------YSQQC
 .| . |.| | . ...|.|.. |.|||||.|||. |.  .. |.  |..||. ||||| . .. ..  .   |||| |.||||.   .      |...|
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKN--CSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKC

DIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAV-WNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWL
|.||.||..| || |.||| . ...  .....| .. |.  . |. .|. .|  .|.. ..|| .||||...|...| 
DMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase STK33.AA S_TKc 116-381 31 8.2e-97 328.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-231/231
Sequence Identity: 31% (88 aa)

YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCED--GELKEILDRKGH----
|...|..|||.|| |  ...|.|  . |||...         . ..||..|||. .|..|..|  ||.. ...|.|||.|.   |.|.......|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQ-QCDI
  |.| ..| ... ...|..|.|.. |.||||| |||.. .           .||..||||| .            |||| ||||||.    |.   ||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDW

WSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLD-------NQWL
||.|...| .| |.|||    ....|..|.              |. ||. .......||..|.|| |.|         .|.
WSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase STK33.AA CAMKL 116-381 29 2.3e-93 298.28 In-house 1-297 (297) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-297/297
Sequence Identity: 29% (91 aa)

YTFGRILGKGSFGIVIEATD-KETETKWAIKKVNKEKAGSSAVKL-------------LEREVNILKSVK---HEHIIHLEQVFETPKK------MYLVM
|..|. ||||||| |  ||. . |..| ||| ..|.|.    ...             ..||..|.|...   |..||.| .|.|||..      .||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCEDGE--LKEILDRKGH----FSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVK-K-Q-SRSEAMLQAT
|.|. ||  | . ....||    ..|.|.| . . . ||..|.|...|||||.|.|||.. ..          |||..|||.. . . .   .. .|   
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-------NIKIIDFGFSNMYRPCIFGPGQKLKTF

CGTPIYMAPEVISA-HD-YS-QQCDIWSIGVVMYMLLRGEPPFLASSE------EKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKE
||.| |||||...  .. |  .. ||||.||..|... |. || . .        .  .. .. .. ..  .|...|  ... ......|.| .|.|...
CGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ

LLDNQWL
..   |.
IMNHPWM
Kinase STK33.AA RAD53 116-381 34 6.4e-93 277.09 In-house 1-305 (305) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-305/305
Sequence Identity: 34% (105 aa)

YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEK--AGSSAV----KLLEREVNILKSVKHEHIIHLEQVFETP-KKMYLVMELCEDGELKEIL-DRK
| ....||.| ||.| .| .|.|  | ||| ..| |  .... .    . ...||.||| ..|. || .. .|.|| |  |.|.|| ..||| . . ..|
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

GH---FSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLID---------DNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVI
.    |.|.. . .   .  |. |||.| |.||||| |||  ..   .         |  ||.. ||.|||||.  | .    ...  |||| | |||||
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS--KFVGEGSFMKTMCGTPQYVAPEVI

SAH---------------DYSQQCDIWSIGVVMYMLLRGEPPFLAS-----SEEKLFELIRK-GELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKE
                   |.  .|.||.|.. | .| | |||  .     .. .||| |.. | .||.  .| .||. ||.  |.. .||| .|.|..|
TSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDE

LLDNQWL
.|  .|.
ALNHPWM
Kinase STK33.AA Pkinase 116-381 31 6.7e-90 309.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-293/293
Sequence Identity: 31% (96 aa)

YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLER--EVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDG----ELKEILD--RK
|..||..|.|||| | ....| |. ..|.|...|... |.  . . |  |. |.|...|..|. |  .||.....|.|||.|| |    .|....   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GHF--SENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVK-SSLIDDNNEINLNIKVTDFGLAVKK-QSRSEAMLQATCGTPIYMAPEVIS-AHDYSQ
| |  ||.| . ..  ......|.|.. |.|||||.|||...    ||.       .|..||||| ..   ...  ..  |||| |||||||  . .|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA------CVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGP

QCDIWSIGVVMYMLLRGEPPFLAS------SEEKLFELIRKGELHFENAVWNSIS-----------------DCAKSVLKQLMKVDPAHRITAKELLDNQ
 .|.||.|...| .| |.|||  .      .. .....|....|||.   |.|||                 . .|...| . ..||. |.||...|   
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WL
|.
WF
Kinase STK33.AA Ciliate-E2 116-381 21 1.3e-84 287.43 In-house 1-365 (365) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

YTFGRILGKGSFGIVIEATDKETET------------------KWAIKKVNKEKAGSSAVKLLEREVNILK----------------SVKHEHIIHLEQV
| | ...|.|.||.| .......                    | .||.....    . .. ...| .|..                ...| .|| .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TPKKMYLVMELCEDGELKEILDRKGHFS-----------ENETRWIIQSLAS---------------AIAYLHNND-IVHRDLKLENIMVKSSLID
|.  . ...|||||.|. |.|....  . ...           |.| . |.. ...               |. |||..  |.|||.|.|||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

DNNEINLNIKVTDFGLAVKKQSR------------------------------SEAMLQATCGTPIYMAPEVIS---------AHDYSQQCDIWSIGVVM
        ||..||||. | .                                .. | . .|||| |||||...          ..|. .|||||.||..
--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

YMLLRGEPPFLASSEEKLFELIRKGELHFENA--------------VWNSISDCAKSVLKQ----LMKVDPAHRIT-AKELLDNQWL
|..| |.|||        .. | .... | ..               |...|. .|  .|.    ....||  ||| ....|...|.
YEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase STK33.AA Ciliate-E2-Unclassified 116-381 23 4.6e-80 272.29 In-house 1-352 (352) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-352/352
Sequence Identity: 23% (85 aa)

YTFGRILGKGSFGIVIEATDKETE--------TKWAIKKVNKEKAGSSAVKLLEREVN----------------ILKSVKHEHIIHLEQVFETPKKMYLV
|......|.|.||.| .. .|..          |  |.|... .      .. . |.|                ||.. .|..|.... .|.. ...|.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELCEDGELKEILDRKGH-----------------FSENETR-----WIIQSLASAIAYLHNND-IVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGL
||.||.|.|....  ...                 |.|....      ..  . ... ||| .  |.|||.|.|||.....        |..||..|||.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK------NYYIKIIDFGI

AVKKQSR--------------SEAMLQATCGTPIYM----APEVISAHDYSQQ----CDIWSIGVVMYMLLRGEPPFLASSEEK----------------
. | |.               .. |.. .||||.||    ||||.  . |...    ||||| ||..| .| |..|| . ..|.                
SKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQ

LFELIRKGELHFENAVW----NSISDCAKSVLK----QLMKVDPAHRITAKELLDNQWL
|.. | .... | .. |      .|..||  ..    ...|..|  |||....|  .|.
LYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase STK33.AA ULK 116-381 26 3.6e-79 269.31 In-house 1-329 (329) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-329/329
Sequence Identity: 26% (88 aa)

YTFGRILGKGSFGIVIEATDKETE----TKWAIKKVNKEKAGSSAVK--------LLEREVNILKSVK--------HEHIIHLEQVFETP--KKMYLVME
|   ..||||||| | ....|.|.     |.|.|.. |.|   .           ||..|. |.|  |        |..|. |  .|||.  .  |..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCEDGELKEILDRKGH----------FSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLI--DDNNEINLN------IKVTDFGLAVKKQSR
.|..| |.... ....          .||.|.. ... ....  .|| . |.|||.|..||...   .  |.             .|..|||.| . .. 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK-----KVHPNGVLKIADFGFAKHVDND

--SEAMLQATC------GTPIYMAPEVISAH----DYS-QQCDIWSIGVVMYMLLRGEPPFLASSEEKLF-----EL----------IRKGELHFENA-V
  ...|....       |||.||||.... .    .|.   |||||.|...| .| |.||| |.  ....     .|          |.|  | |...  
NMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN

WNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWL
 . ||.  |. .......|.  ||.  ||... |.
DPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase STK33.AA RSK 118-381 29 3.3e-78 266.14 In-house 1-278 (278) Show / Hide 
Range on Protein: 118-381
Range on HMM: 1-278/278
Sequence Identity: 29% (85 aa)

FGRI--LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSA--VKLLEREVNILKSVK-HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGH---
      .|.|.. .. . |.. |..  | | ..| |.  ..  ..   .|.|||. .. |  |..|  .|.|..| ||.||.|. ||| . | ...|   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVIS---AHD-YSQQCD
|||.| . ..  ...|. .||  .|.|||||.|||.      || .  .  ||.||||.. ..  . . ...  |.|  |||||..        ....||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENIL-----YDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACD

IWSIGVVMYMLLRGEPPFLA---SSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRIT-----AKELLDNQWL
.|| ||.||..| | ||| .   .. ..... |.||.. ..   |...|. ||. .......||. |..     |.|.....|.
WWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase STK33.AA Pkinase_Tyr 116-314 28 1.9e-34 117.27 Pfam 1-205 (270) Show / Hide 
Range on Protein: 116-314
Range on HMM: 1-205/270
Sequence Identity: 28% (61 aa)

YTFGRILGKGSFGIVIEATDK----ETETKWAIKKVNKEKAGSSA--VKLLEREVNILKSV-KHEHIIHLEQVFE-TPKK--MYLVMELCEDGELKEILD
 |||. ||.|.|| | ..| |    .|... |.|.. ||.| ...   . . ||..|.|.  .|..|. |  |     .   .|.|||... | |.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----KGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPI---YMAPEVISAH
.    |....  .   . .  |.. .||... ..||||   |..|..         |. .|..|||||   .. ..  .... |...    ||||.|.  
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---------NNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYG

DYSQQCDIWSIGVVMY
 .. . |.|| ||.|.
KFTTKSDVWSFGVLMW
Kinase STK33.AA TyrKc 116-381 22 2.9e-25 91.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 116-381
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSV--KHEHIIHLEQVFETP-------KKMYLVMELCEDGELKEIL-D
 |.|..|| | ||.| ..| |   .. |.|......     .. . || .|....  .|..|. |  |  ..       . ...|||... | ||. | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSR------SEAMLQAT--CGT---PI-YMAPE
......  .   .    |.  .||| . ..||||   |..|.. .          .|..||||. .  .       ..   ...  .|    ||  ||||
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

VISAHDYSQQCDIWSIGVVMY-MLLRGEPPFLA-----SSEEKLFELIRKG-ELHFENAVWNSISD-----CAKSVLKQLMK----VDPAHRITAKELLD
.|  . .. . |.|| ||.|. .. .|..|         | . ..|....|  .     .           | . . . .||     ||. | | .|.  
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----PMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--

NQWL
 . .
HECF