Gene SRM (Human)

SRM

Species: Human
Alias: C20orf148, SRMS, dJ697K14.1, SRM
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 20p11.1-q13.3,

Classification

Group: TK
Family: Src
Subfamily: SRM

Sequence

Name Sequence Type Origin Length Description Download
SRM.NA RNA Sugen Kinome 1547 None Fasta, JSON
SRM.AA Protein Sugen Kinome 488 None Fasta, JSON
SRM.kin_dom Protein Kinase Domain Sugen Kinome 251 None Fasta, JSON

Protein domain

Protein domains of SRM.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 SRM.AA SH3 54-111 28 1.3e-08 35.82 SMART 1-58 (58) Show / Hide 
Range on Protein: 54-111
Range on HMM: 1-58/58
Sequence Identity: 28% (17 aa)

QLFLALYDFTARCGGELSVRRGDRLCALEE-GGGYIFARRLSGQPSAGLVPITHVAKAS
. . ||||..|.  .|||...|| .  ||. ..|   .|. .     |..| ..|..  
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNR-TGQEGWFPSNYVEEID
SH3_2 SRM.AA SH3_2 55-110 11 4e-06 24.21 Pfam 1-68 (68) Show / Hide 
Range on Protein: 55-110
Range on HMM: 1-68/68
Sequence Identity: 11% (8 aa)

LFLALYDFTA-RCGGE-----LSVRRGDRLCAL----EEGGGYIFA-RRLSGQPSA--GLVPITHVAKA
.. .. |... .. .|     |....|| .. .    .. ...... ... ..  .  |..|...|.. 
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETI-WGGRRMRGWFPSQWVEEC
SH3_1 SRM.AA SH3_1 57-78 45 0.000855 15.99 Pfam 1-22 (49) Show / Hide 
Range on Protein: 57-78
Range on HMM: 1-22/49
Sequence Identity: 45% (10 aa)

LALYDFTARCGGELSVRRGDRL
 ||||..|. ..||| ..|| .
VALYDYQAQQPDELSFKKGDII
SH2 SRM.AA SH2 120-197 40 6.1e-33 98.53 Pfam 1-81 (81) Show / Hide 
Range on Protein: 120-197
Range on HMM: 1-81/81
Sequence Identity: 40% (33 aa)

WYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQA---KVCHYRVSMAADGSLYLQKGRLFPGLEELLTYY
||.  .|| .|..||..| |..|.||.|.|||. |.|.|||| .    .| |||.   ..| .|.  .. |. | ||  .|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 SRM.AA SH2 118-203 45 8.8e-32 112.82 SMART 1-87 (87) Show / Hide 
Range on Protein: 118-203
Range on HMM: 1-87/87
Sequence Identity: 45% (40 aa)

QPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSLYLQK--GRLFPGLEELLTYYKANWKL
||||.  .|| .|.|||..| ...|.||.|.|||. |.|.|||| . ||.|||.   .||. |..   .| || | ||. .|. |   
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase SRM.AA SRM 230-481 71 5.6e-219 733.76 In-house 1-253 (253) Show / Hide 
Range on Protein: 230-481
Range on HMM: 1-253/253
Sequence Identity: 71% (182 aa)

FALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSAN-MKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLL
|.|.||||||||||||||||.|...|||||||..| |....|.||||..|.|||...||||||||.|.||||.||||||||||..|......||..|.||
FTLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLL

GFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYE
.|||||||||.|||||...|||||||||||.|...|||.|||||||.||||||||....||.|||||||||||..||||||||||.||||.||||||||.
DFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYP

GMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKLH
|||||||.|||.||||.|.||.||.||..||||||...||.||.|..||||| 
GMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase SRM.AA Src 230-480 56 8.99999999999e-177 593.55 In-house 1-255 (255) Show / Hide 
Range on Protein: 230-480
Range on HMM: 1-255/255
Sequence Identity: 56% (144 aa)

FALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLG-TPEGRALRLPPLL
. | ||||.|.|||||.|.| |. .||.|..|...|. ... .|.|..| ||||.|..|.|||| .||.|||||.|..|.|...|  ..|||.|.|| |.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

GFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLK--DDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCP
 .|.||||||.|||.....|||||||||||.....|||||||||||.|  ||.|.... .|.|.|||||||.||..|..||||||||.||.|..|||..|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YEGMTNHETLQQIMRGYRLPRPAACPAEVYV-LMLECWRSSPEERPSFATLREKL
|.||||||.|||..||||.|.|. ||.|.|  .||.||...||.|| |..|...|
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase SRM.AA SFK-Src 230-484 51 1.3e-141 422.78 In-house 1-259 (259) Show / Hide 
Range on Protein: 230-484
Range on HMM: 1-259/259
Sequence Identity: 51% (134 aa)

FALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLG
 .| .|||.| ||.|| | | ..  ||.|  |.. |      .| | .| |||..||.|.|||  |||.||.||||. | |  .|  |.||.||.| |  
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

FACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLL-KDDI-YSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPY
 | ||| || |||.|  |||||||||||| |   |||.|||..| | .||. | .    | |.|||||||.|.  || ||||||||.|. |. |||  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

EGMTNHETLQQIMR--GYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKLHAIH
.|||| | |||. |  |||.| |  || | |..|..||.  |..|| | .|. ..    
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase SRM.AA Pkinase_Tyr 230-480 44 1.8e-137 466.17 Pfam 1-270 (270) Show / Hide 
Range on Protein: 230-480
Range on HMM: 1-270/270
Sequence Identity: 44% (120 aa)

FALGRKLGEGYFGEVWEGLWL-----GSLPVAIKVIKSANMKL----TDLAKEIQTLKGL-RHERLIRLHAVCS-GGEP--VYIVTELMRKGNLQAFLGT
  .|.||||| ||||..| |      . .|||.|..|   |.      |. .|....| | .|. ..||..||.  |||  .|||.|.| .|.|  .| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

P--EGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLL-KDDIY-SPSSSSKIPVKWTAPEAANYRVFSQKSDVWSF
.  ....| .. ||... |.|.||.|||... .||||||||.||.... .|..||||||.. .|| |   ....|.|.||.|||. ||..|. |||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVLLHEVFTYGQCP-YEGMTNHETLQQI-MRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKL
|||. |.||||. | |.||.|.| ...|  .|||.|.|  ||.|.| ||..||.  ||.||.|. ..|.|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase SRM.AA TyrKc 230-480 38 4.3e-133 449.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 230-480
Range on HMM: 1-280/280
Sequence Identity: 38% (111 aa)

FALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGL--RHERLIRLHAVCSGG-------EPVYIVTELMRKGNLQAFLGTPEGR
  ||.||||| ||||..| |   ..||.|..|.    . |. .|.. .. |  .|. ..||..||. .       ||..||.|.| .|.|. .|  ....
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

ALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDD--------IYSPSS--SSK--IPVKWTAPEAANYRVFSQKSD
 | .. || |. |.|.||.||......||||||||.||.... .|..||||.| ..||         |....  ..|  .|..|.|||. ||..|. |||
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGVLLHEVFTYGQCPYEG-----MTNHETLQQIMRGYRLPRPAA--------CPAEVYVLMLECWRSSPEERPSFATLREKL
||||||.. |.||||| ||.|     |.| | ......|||.|.|.         ||.|.| .|..||.  ||.||.|....|..
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase SRM.AA Frk 230-484 53 1.6e-120 406.7 In-house 1-260 (260) Show / Hide 
Range on Protein: 230-484
Range on HMM: 1-260/260
Sequence Identity: 53% (140 aa)

FALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLG--TPEGRALRLPPL
  | |.|| | |||||||||  . |||.| .|.  |  .|. .| | .| ||| .||.|.|||   ||.||.|||||.| || .|   . .|| .... |
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

LGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLAR-LLKDDI--YSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQ
.  | ||| || |||.|  .|||||||||||.... ||.||||||| |.||..  |      ..|.||||||||||  |. ||||||||.|| |. |||.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

CPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKLHAIH
 || |||| | ||.. .|||.|.|. || ..| .|||||.| |..|| | ||. ||    
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase SRM.AA TK 230-480 25 4.90000000001e-117 394.07 In-house 1-486 (486) Show / Hide 
Range on Protein: 230-480
Range on HMM: 1-486/486
Sequence Identity: 25% (122 aa)

FALGRKLGEGYFG---EVWEGLWLGSL--------------------------PVAIKVIKS-ANMKLTD-----------------LAKEIQTLKG--L
  ||.||||| ||   ||..|.| |                            |||.|..|. ..|  ..                 .| |.. ..   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHERLIRLHAVCSGG------------EPVYIVTELMRKGN----LQAFLG--TPEGRA-----------------------------------------
.|. ..||..||. |            ||..||.|.| .|.    |. .|    |...                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LRLPPLLGFACQVAEGMSYLEEQ------RVVHRDLAARNVLVDDGLA-----------CKVADFG---
                               | .. || ...|.|.||.||...      ..|||||||||.||....            ||.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARLL-KDDIYSPSS------------------------SSKIPVKWTAPEAANYRV---------FSQKSDVWSFGVLLHEVFTYG-QCPYEGM
     ||| . .|| |  .|                        . |.|..|.|||. |.||         |. ||||||||||..|.|||| . .|.||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------HETLQQIMRG--------------YRLPRPAACP--------------AEVYVLMLECWRSSPEERPSFATLREKL
.|         .| .... ||              .|.|.|. ||              .|.| ||..||.  ||.||.|..|.|.|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SRM.AA SrcA 230-480 52 4.3e-114 362.02 In-house 1-250 (250) Show / Hide 
Range on Protein: 230-480
Range on HMM: 1-250/250
Sequence Identity: 52% (132 aa)

FALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLG
 .| |.||.| ||||| | | |.  |||| .|   |      .| | .| |||..|..| || |  ||.||||| | || |  ||  .||..|.|| |  
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

FACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEG
 | |||||| |.|    .|||| | |.|| . |.||.||||||||..|. | .   .| |.|||||||| |  |  ||||||||.|| |. | |  || |
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG

MTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKL
| | | |.|. |||..| |  ||. .. || .|||  ||||| |  |   |
MNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase SRM.AA Src-Unclassified 230-480 41 8.8e-108 364.37 In-house 1-284 (284) Show / Hide 
Range on Protein: 230-480
Range on HMM: 1-284/284
Sequence Identity: 41% (119 aa)

FALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSA---NMKLTDLA--------KEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPE
  | |||| | ||||| | | |.  ||.|  .      |  .           .| |..| .|| .|. | ||||  || ||.||.| .| | ..| .  
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

GRALRLPPL------------LGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGL-----ACKVADFGLA--RLLKDDIYSPSSSSKIPVKWTAPEAAN
|. | .. .               | ||| || |||. . |||||||||||. .         ||.|||||  .|  ||.| .   .. |.||.|||.. 
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRP--AACPAEVYV-LMLECWRSSPEERPSFATLREKL
|  || ||||||.|.|| |..|.|| || || | |.| .. ||||.|.|    ||  .|  .|. ||   |. || | ||   .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase SRM.AA UTK 230-480 35 1.5e-107 363.56 In-house 1-296 (296) Show / Hide 
Range on Protein: 230-480
Range on HMM: 1-296/296
Sequence Identity: 35% (104 aa)

FALGRKLGEGYFGEVWEGLW------LGSLPVAIKVIKSANMKLTDLA------KEIQ---TLKGLR-HERLIRLHAVCSGGEPVYIVTELMRKGNLQAF
 .|||.||.| |||| .. .       . . ||.|| ..  .. .. .      .| .    .| .. |. ..|| .||. .|| .||||.|..|.|...
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LG--TP----EGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDG-------LACKVADFG---LARLLK----------DDIYSPSSSSK
|   .|    .. .|.|  .|..| ..|.||.||.....|||||||||.||..        . ||.||||   ..|...          .. | ...  .
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

IPVKWTAPEAANYR-VFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRG--YRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKL
.|..|.|||| ...  |..|||||||||...|..|.|. ||.||.|.....|...|  ||.|.|..||..|| ||..||...|.|||.| .|....
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase SRM.AA SrcB 230-481 50 5e-107 361.86 In-house 1-251 (251) Show / Hide 
Range on Protein: 230-481
Range on HMM: 1-251/251
Sequence Identity: 50% (126 aa)

FALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLG
  | .||| | ||||| | . ..  ||.| .|   |      .|   .| | |.||.||.|| .  ||.||.|| | || |  || |.||  | || |. 
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVT-KEPIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

FACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEG
.. |.|||| |.|..  .|||| | |.|| . | ||.|||||||.. |. |      | |.||||||| |. .|  ||||||||.|| |. |||. || |
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKLH
||| | .... ||||.|||  || |.| .| .||.. ||||| |  |.  | 
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase SRM.AA Src-Echino1 231-480 47 1.9e-103 349.97 In-house 2-252 (252) Show / Hide 
Range on Protein: 231-480
Range on HMM: 2-252/252
Sequence Identity: 47% (119 aa)

ALGRKLGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGF
 . .|.|.| .||||.|.| |  |||.| .|   |   |.  |   .| .||| .....||||  ||.|||||||..||||..|   ... .... |.  
RMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLIDM

ACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGM
  ..| || ||... |||||||||||||..|  ||.|||||||....|.|      |.|.|||||||| |  |  ||||||||.|. |. |.|. ||.||
GAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPGM

TNHETLQQIMRGYRLPRPAACPAEVYVL-MLECWRSSPEERPSFATLREKL
.|.| |.|. ||||.|..  ||  .| . |. ||   |  || |  | . .
MNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase SRM.AA S_TKc 230-484 23 2.2e-45 158.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 230-484
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

FALGRKLGEGYFGEVWEGLWLG-SLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRK--GNLQAFLGTPEGRA----L
. ..||.|.| ||.|. . . .    ||||.||       .. .||| ||  .|. ...|. |.   . .|.|.|..    |.|  ..    ..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

RLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQ-KSDVWSFGVLLHEVFT
       ...|..... |. .....||||   |.|.|.    |..||||||.|        ..      . |||      ..  |.|.||.|..| | ..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

YGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLRE-----KLHAIH
 |. |..  . ......|.           . |.  ..  |..  ||.||.   . .     |.|   
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SRM.AA Pkinase 230-480 23 3.3e-41 146.77 Pfam 1-293 (293) Show / Hide 
Range on Protein: 230-480
Range on HMM: 1-293/293
Sequence Identity: 23% (69 aa)

FALGRKLGEGYFGEVWEGLWLGS-LPVAIKVIKSANMKLTDLAK-----EIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKG----NLQAFLGTPEG
. .|||.|.| ||.|... . |.   ||.|.||  . |   .       ||| .| |.|.  .||. ..  .  .|.|.|....|     | ... | ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RAL--RLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLAC----KVADFGLARLLKDDIYSPSSSSKIPV---KWTAPEAAN-YRVFSQKSDV
...      .  .. |...|. |. .....||||   |.|.|.   .    |..|||||....   | ..|  . ..    . |||  . ..  ..|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGVLLHEVFTYGQCPYEGM------TNHETLQQIMR-GYRLPRPAACP-------------------AEVYVLMLECWRSSPEERPSFATLREK--L
||.|..|.|... |. |. |       .  . ...||.  .. ..|  |.                    |   ..  |..  |..||... . .   .
WSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF