Gene SgK288 (Human)

SgK288

Species: Human
Alias: PKK2, ANKK1, SgK288
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 11q23.2,

Classification

Group: TKL
Family: RIPK

Sequence

Name Sequence Type Origin Length Description Download
SgK288.NA RNA Sugen Kinome 2641 None Fasta, JSON
SgK288.AA Protein Sugen Kinome 765 None Fasta, JSON
SgK288.kin_dom Protein Kinase Domain Sugen Kinome 255 None Fasta, JSON

Protein domain

Protein domains of SgK288.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SgK288.AA RIPK 28-285 47 9.80000000001e-162 543.61 In-house 1-290 (290) Show / Hide 
Range on Protein: 28-285
Range on HMM: 1-290/290
Sequence Identity: 47% (138 aa)

VASGGFSQVFQARHRRWRTEYAIKCAPCLPPDAA--SSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQP--------LGIVMEFMANGSLEKVLSTHS---
|..|||..||.||||.|....|.||.||......  .....|..|||..|.|....|||.|||.|...        .|||||.|.||||...|.|..   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

---LCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQ--------YIERSALR-GMLSYIPPEMFLESNKA
   ..|.||.|.|||.|..|..|||..||..|.||||.|||.|.|.||||.||||..||..|...|        |...|..| |.|||.|||.|...||.
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

P----GPKYDVYSFAIVIWELLTQKKPYSG-FNMMMIIIRVAAGMRPSLQPVSDQWPS--EAQQMVDLMKRCWDQDPKKRPCFLDITIET
|    .|||||||||||.||.||||.||.. ..||||......|.||.||||...||.  ...||..||.|||.|||..||||.... .|
PIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase SgK288.AA TKL 28-285 25 1.1e-86 294.36 In-house 1-364 (364) Show / Hide 
Range on Protein: 28-285
Range on HMM: 1-364/364
Sequence Identity: 25% (94 aa)

VASGGFSQVFQARHRRWR--------TEYAIKCAPCLP-----------------------PDAASSDVNYLIEEAAKMKKIKFQHIVSIYG--------
. ||||..|.....| |.        .. |.|  .                           . ||     ..||.  |.... ..||...|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-VCKQP------LGIVMEFMANGSLEKVLSTHSLCWKLRFRIIHETSLAMNFLHSIK------PPLLHLDLKPGNILLDSNMH--------------VKI
 || .|      |.||||.. .|||. .|      | .|.|........||.||| .      ||..| |||. |||.|.|..              .||
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

SDFGLSKWMEQSTRMQYIE---------------RSALRGMLSYIPPEMFLES--------------NKAPGPKYDVYSFAIVIWELLTQKKPYSGFNM-
.|||||..|.||. |. ..               ..  .| . . .||.. ..              ..   .| |||||.||.||.|| ..||..... 
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

---------MMIIIRVAAGMRPSLQPVSD-----QWPSEA-QQMVDLMKRCWDQDPKKRPCFLDITIET
         .|.....  |.|| . |.       .... . ..| .||..|||.||.||| |..|. . 
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase SgK288.AA TKL-Unique 24-285 28 4.6e-52 179.29 In-house 1-290 (290) Show / Hide 
Range on Protein: 24-285
Range on HMM: 1-290/290
Sequence Identity: 28% (86 aa)

DWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDAASSDVNYLIEEAAKMKKIK-FQHIVSIYGVCK----QPL--GIVMEFMANGSLEKVLS-----
.| .. .||..||... .|  ....|||       |  .. .  ...|   |||..    || ..|.|.    .|    ||||..  ||| .||.     
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNN

------THSLCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSN-----MHVKISDFGLSKWMEQSTRMQYIER-----SALRGMLSYIPPEM
       . | ...| ....  ...|..||. .|| .|.|||. |.|.|.|     . .||.||||||   ....| ..|      .   | . ...||.
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

FLESNKAPGPKYDVYSFAIVIWELLTQKK------PYSGFNMMMIIIRVAA---GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIET
.  ...    | |||||.|| ||..| |       ||.|..   ..  |.    . ||   |... .|   ..  ||...||..|| .|| | .|  . 
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRP---PIPNHCP---KEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase SgK288.AA MLK 59-285 28 4.8e-41 140.15 In-house 46-291 (291) Show / Hide 
Range on Protein: 59-285
Range on HMM: 46-291/291
Sequence Identity: 28% (73 aa)

DAASSDVNYLIEEAAKMKKIK-FQHIVSIYGVCKQP---LGIVMEFMANGSLEKVLSTHS---------------LCWKLRFRIIHETSLAMNFLHSIKP
.. . |..  .........   .  |. .||||.||   ..||||....|||  || . .                   . ... .  . .|..||| .|
YCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAP

-PLLHLDLKPGNILLDS------NMHVKISDFGLSKWMEQS-T-RMQYIERSALRGMLSYIPPEMFLE-SNKAPGPKYDVYSFAIVIWELLTQKKPYS-G
 |. | |||. |||.|       ....||.|||.|. . |. | .|        .| . .  ||..    .     | ||.|...|.||.|| . ||. .
KPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMM------SNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQH

FNMMMIIIRVAAGM-RPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIET
 . |.|.. ||.   || . .           .  |||.||.|||.||| |  |  . 
YDPMAIAWWVAYNGLRPPIPST------CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase SgK288.AA S_TKc 26-289 21 1.1e-37 132.41 SMART 5-231 (231) Show / Hide 
Range on Protein: 26-289
Range on HMM: 5-231/231
Sequence Identity: 21% (61 aa)

RLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDAASSDVNYLIEEAAKMKKIKFQHIVSIYGVCK-QPLGIVMEFMAN--GSLEKVLSTHS-------L
|.. .|.|..|...||..   ..|||. .           . .. | . .|| .  .|| .|.|.  . | .|||.. .  |.| ...  .        .
RKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

CWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFLESNKAPGP-KYDVYSFAI
      ...... .|....||     .| |||| |||||.  |.||.||||.. .           . . | . |..||..       |. | |..|. .
PE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGC

VIWELLTQKKPYSGFNMMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIET-----DILL
...|.|. . |..    |. ....                   ... |....|.. ||.|||   ..  .      .  .
ILYEMLCGYPPFP---QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SgK288.AA Pkinase 26-276 24 4.9e-36 128.5 Pfam 5-282 (293) Show / Hide 
Range on Protein: 26-276
Range on HMM: 5-282/293
Sequence Identity: 24% (70 aa)

RLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDAASSDVNYLIE---EAAKMKKIKFQHIVSIYGVC--KQPLGIVMEFMANG----SLEKVLS---TH
| . ||.|..|....|.  . ..|.|   ... . ..|....      |.. ||...  .|| .|...  |. . .|||.. .|    .|  ..|     
RKIGSGSFGCVYKCHHKGTGKIVAVK---IIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHG

SL--CWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHV----KISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFLESNKAPGPKY
..   ..   ... ..  .....||     .| |||| |||.|.|.|.    ||.||||.| ..      .   . . | . |..||  . ...  ||| 
CFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEV-IRGGQYYGPKV

DVYSFAIVIWELLTQKKPYSGF----NMMMIIIRVAAGMRPSLQPVSDQWPSEA-----------------QQMVDLMKRCWDQDPKKRP
|..|. ....|.|. . |..|     | .  . ...  |.| |   ...| |.                  . . |..|.|...||||||
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP
Kinase SgK288.AA TK 33-285 15 1.3e-33 109.43 In-house 12-486 (486) Show / Hide 
Range on Protein: 33-285
Range on HMM: 12-486/486
Sequence Identity: 15% (75 aa)

FS---QVFQARHR---RWRTEYAIK-------------------CAPCLPPDAASSDVNYLI-------------EEAAKMKKIK-----FQHIVSIYGV
|    .|.... |   .|. .....                      .| ...|.|.   .              |||. ||. .      ..||..|||
FGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGV

C--------------KQPLGIVMEFMANGS----LEKVLSTHS---------------------------------------------------------
|              ..|. ||||.|..|.    | . | ...                                                         
CTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPP

--------------------LCWKLRFRIIHETSLAMNFLHSIKP----PLLHLDLKPGNILLDSNMH-----------VKISDFGLSKWME--QSTRMQ
                    |. . .  . .  . .| .||| .      . | ||   |.|...|..           .||.|||||. ..   . ...
LTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIY

---YIERSALRGMLS-------------------------YIPPEMFLES-------NKAPGPKYDVYSFAIVIWELLT--QKKPYSGFNM---------
   .  |.  .|.                           . .|| ...        ..   .| ||.|| ...||..|  |. .| | .          
SDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDN

MMIIIRVAAG--------------MRPSLQPVSDQWP-------SEAQQMV-DLMKRCWDQDPKKRPCFLDITIET
  .. .. .|              ||.   |    |.       ... ... |||..||. ||..|| | ..  . 
QEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SgK288.AA STE 25-276 19 1.9e-28 97.65 In-house 1-346 (359) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-346/359
Sequence Identity: 19% (72 aa)

WRL---VASGGFSQVFQARHRR---------------WRTEYAIKCAP---CLPPDAA-----------SSDVNYLIEEAAKMKKIK--FQHIVSIYGVC
|..   . .|.| .|..|...                  . .|||  .   | . |             ..... ...|   ||| .   ..||  || .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

KQP---------LGIVMEFMANGSLEKVLSTHSLC---------------WKLRFRIIHETSLA-MNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFG
 .          | |.||.|..|||.... .   |                ..  .|....  . ...||| .    | |.||.||||     ||..|||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFG

LSKWMEQS--TRMQYI------------ERSALRGMLSYIPPEMFLES----NKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMM----MII--IRVAA-
... ...|     | .            .|  . |   .  ||. .      .|  . | |..|. ..|.|..| | |.. .. |    ||.  ..... 
VCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ

--------GMRPSLQP-----------VSDQWPSEA---------QQMVDLMKRCWDQDPKKRP
        |  |.|..           .                 . . | ...| . ||.|||
FEQLCIVNGPPPPLPDHLSQNEMISYGG-------SGTTYPHKWSPEFKDFINKCLQKDPNKRP
Kinase SgK288.AA TyrKc 26-288 27 6.3e-26 93.37 SMART 5-280 (280) Show / Hide 
Range on Protein: 26-288
Range on HMM: 5-280/280
Sequence Identity: 27% (80 aa)

RLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDAASSDVNYLIEEAAKMKKI--KFQHIVSIYGVCK---------QPLGIVMEFMANGSLEKVLSTHS
.   .| | .|.... .   .. |.|.            .  ...||  |.|.  . ..|| .||||          .|| ||||.|..|.| . |  | 
KKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQS----TRMQYIERS---ALRGMLSY--IPPEMFLESNKAP
  ||.|    . .  .  |..|||   .. | ||   |.|...| .|||||||||.  .       . .|.  .     ..|| .   .|| .    .  
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF

GPKYDVYSFAIVIWELLTQ-KKPYSG-----FNMMMIIIRVAAGMRPSLQPV-----SDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDIL
 .| ||.|| ...||..|  ..||.|      .   .| .| .|.|.   |      .   .   . | ..||.||. ||..||.| .|    ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase SgK288.AA LRRK 82-176 33 6.5e-25 85.07 In-house 118-233 (351) Show / Hide 
Range on Protein: 82-176
Range on HMM: 118-233/351
Sequence Identity: 33% (39 aa)

HIVSIYGVCKQPLGIVMEFMANGSLEKVLS---THS-------LCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILL---D---------SNMHV
.|||..|.| .|| .|||.. .|.| ..|.    ..       . | |. .|  . . .|..||| .||..| |||. ||||   .          ....
NIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCA

KISDFGLSKWMEQSTRM
||.|||.|  | |...|
KIADFGISR-MFQCFHM
Kinase SgK288.AA Pkinase_Tyr 55-168 31 1.4e-23 80.44 Pfam 35-159 (270) Show / Hide 
Range on Protein: 55-168
Range on HMM: 35-159/270
Sequence Identity: 31% (40 aa)

CLPPDAASSD--VNYLIEEAAKMKKI-KFQHIVSIYGVCK---QP--LGIVMEFMANGSLEKVLSTH-----SLCWKLRFRIIHETSLAMNFLHSIKPPL
.|...| ...     ...||. ||.. . ..||. ||||    .|  . ||||.|..|.| . | .|     .|. |    . .. . .|..|.|..  .
MLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--C

LHLDLKPGNILLDSNMHVKISDFGLSK
 | ||   |.|...|..|||.||||..
IHRDLAARNCLVTENNVVKICDFGLAR
Kinase SgK288.AA ARK 81-174 32 1.1e-20 71.97 In-house 56-157 (280) Show / Hide 
Range on Protein: 81-174
Range on HMM: 56-157/280
Sequence Identity: 32% (33 aa)

QHIVSIYGVCKQP------LGIVMEFMANGSLEKVLSTHSL--CWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQ
.|.|. ||.|. |      | .|||.  .||| ..... ..   | . |.  ... .  | ||. .|...| |||  |.|  .|  .|..|||||. .. 
PHVVYFYGACIEPEPQKQKLCMVMEYCSRGSLYHIMNNNKMDFGWDRFFKWMMQMVRGINCLHNWTPQIVHRDLKSLNLLVNENWTCKVCDFGLSRFNTM

ST
|.
SN
Kinase SgK288.AA Dicty4 208-287 35 3.5e-19 60.8 In-house 199-277 (277) Show / Hide 
Range on Protein: 208-287
Range on HMM: 199-277/277
Sequence Identity: 35% (30 aa)

DVYSFAIVIWELLTQKKPYS--GFNMMMIIIRVAA-GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIE--TDI
|||||.|| ||.|| . ||.  . . | ... |.  ..||   |..|. |       .|...||| ||..|| |  |. .   . 
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRP---PIPDWCP---PSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase SgK288.AA Dicty4 75-170 34 1e-18 59.17 In-house 52-164 (277) Show / Hide 
Range on Protein: 75-170
Range on HMM: 52-164/277
Sequence Identity: 34% (39 aa)

MKKIKFQHIVSIYGVCK----QP--LGIVMEFMANGSLEKVLST--------HSLCWKLRFR---IIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNM
|.||   .|.  .| |     .|  . ||.|.|  |.|...|           .| | |. |   .   . . || ||.  |  .|.|||. |.| | |.
MCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNW

HVKISDFGLSKWM
 ||..|||||. |
RVKVCDFGLSQYM
Kinase SgK288.AA DRK 206-281 38 3.1e-18 58.4 In-house 182-252 (258) Show / Hide 
Range on Protein: 206-281
Range on HMM: 182-252/258
Sequence Identity: 38% (30 aa)

KYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAA-GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDI
| |||||||| ||..| . || | . . ... |   ||||   |.  . |      . ||..||. ||  || . ..
KADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMRP---PMPQWCPP---KYIQLMNDCWNEDPQHRPSMQEC
Kinase SgK288.AA LRRK 206-290 30 3.1e-17 57.53 In-house 262-351 (351) Show / Hide 
Range on Protein: 206-290
Range on HMM: 262-351/351
Sequence Identity: 30% (30 aa)

KYDVYSFAIVIWELLTQK-KPYSGFN-------MMMIIIRVAAGMRPSLQPV-SDQ---WPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLS
| |.|||....||||| .  |. ...       | .|  ..  | ||.. .    .   |.     . ||.. ||..|||||| | .|   ...| .
KVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWH----MYQDLIQHCWQHDPKKRPHFSQI---VKRLSQ
Kinase SgK288.AA DRK 96-167 39 4.2e-14 44.2 In-house 74-147 (258) Show / Hide 
Range on Protein: 96-167
Range on HMM: 74-147/258
Sequence Identity: 39% (29 aa)

IVMEFMANGSLEKVLSTHS--LCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLS
|.||.|  ||| ..|   |  . | |. ..       |..||.  |  .| |||  | | | .  ||..|||||
ICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLS
Kinase SgK288.AA Pkinase_Tyr 208-288 32 1.8e-08 29.28 Pfam 196-270 (270) Show / Hide 
Range on Protein: 208-288
Range on HMM: 196-270/270
Sequence Identity: 32% (27 aa)

DVYSFAIVIWELLT-QKKP-YSGFNMMMIIIRV-AAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDIL
||.|| ...||..|  ..| | |     .. ..   | |  . .  .  | |   . ||||.||..||..|| | .|     .|
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPC-PENCPDE---IYDLMKQCWHYDPEDRPTFSEI---HEQL
Kinase SgK288.AA ARK 258-284 44 6e-06 17.95 In-house 254-280 (280) Show / Hide 
Range on Protein: 258-284
Range on HMM: 254-280/280
Sequence Identity: 44% (12 aa)

QQMVDLMKRCWDQDPKKRPCFLDITIE
.| ..| ..|||||| .||   .| .|
EQLKNLIQCCWDQDPDNRPSCEEIMEE
Kinase SgK288.AA ARK 208-221 50 0.004699 7.3 In-house 197-210 (280) Show / Hide 
Range on Protein: 208-221
Range on HMM: 197-210/280
Sequence Identity: 50% (7 aa)

DVYSFAIVIWELLT
||||..|. ||. .
DVYSMGIIMWEMVY
Ank SgK288.AA Ank 493-525 45 2.7e-09 37.81 Pfam 1-33 (33) Show / Hide 
Range on Protein: 493-525
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

EGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQR
.| ||||.|.. ||.. ||.| ..||...|| .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 625-657 54 3.1e-09 37.56 Pfam 1-33 (33) Show / Hide 
Range on Protein: 625-657
Range on HMM: 1-33/33
Sequence Identity: 54% (18 aa)

VNWTPLHLAARHGEEAVVSALLQCGADPNAAEQ
  .||||||.|.| . ||. |||.|||.||   
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 460-492 36 4.5e-09 36.97 Pfam 1-33 (33) Show / Hide 
Range on Protein: 460-492
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

EGWTPLHLAAQNNFENVARLLVSRQADPNLHEA
.|.||||||.... ..|...|... ||.|..  
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 427-459 45 7.8e-09 36.13 Pfam 1-33 (33) Show / Hide 
Range on Protein: 427-459
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

DGWAPLHFAAQNGDDGTARLLLDHGACVDAQER
||. ||| |...|.   ...||.|||.|.|| .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 691-723 42 1e-07 32.09 Pfam 1-33 (33) Show / Hide 
Range on Protein: 691-723
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

VGWTPAHLAALKGNTAILKVLVEAGAQLDVQDG
 |.|| |||...|.| ..| |...|| ...|| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 658-690 42 1.4e-07 31.6 Pfam 1-33 (33) Show / Hide 
Range on Protein: 658-690
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

SGWTPLHLAVQRSTFLSVINLLEHHANVHARNK
 |.||||||...     |  ||.| |.|.|...
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 592-624 39 2e-07 31.05 Pfam 1-33 (33) Show / Hide 
Range on Protein: 592-624
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

QGWTPLHLAAYKGHLEIIHLLAESHANMGALGA
 |.||||||...||.|.. .| .  |.  |   
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 526-558 39 3e-07 30.43 Pfam 1-33 (33) Show / Hide 
Range on Protein: 526-558
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

NLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQ
. .||||||...| .. .. ||. || ..| | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 394-426 39 1e-06 28.33 Pfam 1-33 (33) Show / Hide 
Range on Protein: 394-426
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

SGYTPLLIAAQDQQPDLCALLLAHGADANRVDE
 |.||| .|..  ... . .|| |||| | .| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 559-591 36 2e-06 27.76 Pfam 1-33 (33) Show / Hide 
Range on Protein: 559-591
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

SGYGPLHTAAARGKYLICKMLLRYGASLELPTH
 |. ||| |. .| . ..|||| .||.. . . 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank SgK288.AA Ank 361-393 39 9.5e-05 21.39 Pfam 1-33 (33) Show / Hide 
Range on Protein: 361-393
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

NKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTA
.  ||||  .  |..| |..|| |  ||. |. 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD