Gene SGK2 (Human)
SGK2
Sequence
Protein domains of SGK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | SGK2.AA | SGK | 95-352 | 64 | 4.3e-224 | 699.64 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-283/283 Sequence Identity: 64% (182 aa) FDFLKVIGKGNYGKVLLAKRKSD------------------GAFYAVKVLQKKSIL-------KKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKL ||||||||||..|||...|.|.| ..|||.|||||..|. ||||| ||||||.|.|||..|||.|.|.|.|||..|| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE |||.|||||||.|.|||||..|.|.||||||||...|..||||..||||||||||||||.|||..||||||||||....|||.||||||||||||||||. YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFF |.||.|||||||.|||||..|||||||....|||.||..|||||| .....|.||.| ||.||...|||.|.||.|||||.|| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
|||||||||
Kinase | SGK2.AA | AGC | 95-352 | 36 | 1.3e-186 | 487.73 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-395/395 Sequence Identity: 36% (146 aa) FDFLKVIGKGNYGKVLLAKRK------SDGAFYAVKVLQKKS-ILKKK--EQSHIMAE------------RSVLLKNVR---------HPFLVG-LRYSF |.|||||||| .||| |...| . | .||.|||.|| |..|| .. |.|.| | .| | |||.| | ||| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTPEK--LYFVLD----YVN-----GG-ELFFHLQ---RERRFLEPRARFYAAE-------VASAIGYLHS-LNIIYRD-LKPENILLDCQGHVVLTDFG |.... ||||.. ||| || |||.||| .|.|| |.|||||||| ...|. |||| ..||.|| ||||||||| .||. ||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LCKEGVEPE--------------------------------------------------DTTSTFCG--TPEYLAPEVLRKEPYDRAVDWWC--LGAVLY |||||. . |.|.|||| ||||.|||.| |..|.|||. ||...| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMLHGLPPFYSQDVS----------QMYENIL------HQPLQIP----------GGRTVAACDLLQSLLHKDQRQRLGSKAD------FLEIKNHVFF ||| |.||||.... .|...|. ......| .. | ||.. ||.|| ..|||.. . . ||||| .| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
|||||||||
Kinase | SGK2.AA | Akt | 95-352 | 55 | 2.6e-162 | 522.74 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-264/264 Sequence Identity: 55% (148 aa) FDFLKVIGKGNYGKVLLAKRKSDGAFY-AVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLE ||||||.||| .|||.|.| |... .| | |||.|. |..|.. |...|| . |....|||.|.| |||||..|||||.||.||||||.||||.||| | FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNI-LQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE PRARFYAAEVASAIGYLHSLNIIYRD-LKPENILLDCQGHVVLTDFGLCKEG-VEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWC-LGAVLYEMLHG .|||||.||. .||..||| |||||| |||||||.| .||. |||||||||. . |.| ||||||||||||.| . ...||||| ||.|.|||..| DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG LPPFYSQDVSQMYENILHQPLQIP--GGRTVAACDLLQSLLHKDQRQRLGSKAD-FLEIKNHVFF .||||.||. ||...|. ||...| .. ||. .||.|| .|||.. . |||.| .| RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
|||||||||
Kinase | SGK2.AA | PKC | 95-352 | 45 | 6.4e-128 | 416.8 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-262/262 Sequence Identity: 45% (119 aa) FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEP |.||||.|||..|||.||.|| .||.||| | |.. |.|. || .||||..| .|||...|.||. ||||| | || |. ||| |. FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE RARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPF .|||||||...| .||. .||||||| .|.|||. ||. ..|||.|||.. ..||||||||||.|.|||.|. ..| .|||| .| .|||. | .|| HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF YSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKAD----FLEIKNHVFF .| .. ..|.|. .| .. | ....... |. .|||.. . . .|. | || HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
|||||||||
Kinase | SGK2.AA | AktR | 95-352 | 43 | 1.2e-127 | 430.36 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-268/268 Sequence Identity: 43% (117 aa) FDFLKVIGKGNYGKVLLAKRK-SDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLE |...|..|||..||| |...| .. .|| |.. || | ... ..|. || .. . ..|||.| | |.||| |||.|...|. |||||.||.....| | FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE PRARFYAAEVASAIGYLHSL-NIIYRDLKPENILLDCQGHVVLTDFGLCK-EGVE-PEDTTSTFCGTPEYLAPEVLRK-EPYDRAVDWWCLGAVLYEMLH .||||.|.. |. |||. ||||||||||||||| ||| .||||| | .... .... .|||||||.|||...| ......||||..|...|||. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GLPPFYSQDVSQMYENILHQP-LQIPGGRTV--AACDLLQ-SLLHKDQRQRLG-SKADFLEIKNHVFF |.||||... ||...|. .. ...| . .. ||.| || |....||| ..... |||.| .| GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
|||||||||
Kinase | SGK2.AA | PKA | 95-352 | 43 | 9.69999999999e-120 | 404.1 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-263/263 Sequence Identity: 43% (115 aa) FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVG-LRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLE |......|.| .|.| |.. |..| .|| |.| | | . | . |.. |... |.|..|||.| . ..||.. .||.|..||.|||.| .|....|| . FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNI-LQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN PRARFYAA-EVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE-PYDRAVDWWCLGAVLYEMLHGL | |.|||| .. .|. ||||.|||||||||||||.| .||. .|||| |. .. |.| ||||||||||.. . .. ..||||.|| . |||| | PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY PPFYSQ--DVSQMYENILHQPLQIPGGRTVAA---CDLLQSLLHKDQRQRLGSKA-DFLEIKNHVFF |||| |. |.|| |. .. | ...| ||. .|| .| .|.|.. . |||| .| PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
|||||||||
Kinase | SGK2.AA | RSK | 98-352 | 43 | 2.8e-115 | 389.28 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 98-352 Range on HMM: 1-278/278 Sequence Identity: 43% (121 aa) LKVIGKGNYGKVLLAKRK---SDGAFYAVKVLQKKSILKK-KEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERR--- ||| |.| |||| | ... | ||.|||.|. | .. | . | |.||..|. .|||.| | |.|||..||| ...|..||||| |||.|.. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDC---QGHVVLTDFGLCKEG-VEPEDTTSTFCGTPEYLAPEVLR---KEP-YDRAVDWWCLGA | | .|.||.||...|. .||.. ||.|||||||||.| .||..|||||.||.. . . | |||.| ||.|||.|. .. .|.|.||| ||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV VLYEMLHGLPPFYS---QDVSQMYENILHQP--LQIP--GGRTVAACDLLQSLLHKDQRQRLGS-KADFLEIKNHVFF ..|||| | |||.. .. .. ..|.. | .| . .| ||.. .||.| .|||. . | |||.| .| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
|||||||||
Kinase | SGK2.AA | p70 | 95-352 | 41 | 8.60000000001e-109 | 367.73 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-299/299 Sequence Identity: 41% (123 aa) FDFLKVIGKGNYGKVLLAKRKS---DGAFYAVKVLQKKSILK-KKEQSHIM-------------------------AERSVLLKNVRHPFLVGLRYSFQT | |||.||| ||||.. . | || |||.| .|. | | |||.. | | |||.. | |.||| FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNI-LEEVKHPFICDLHYAFQT PEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDT----------TSTFC .||| .|.| ||||| || |. ..| |.||..|. |...||.. ||||||||||..|. |||||||||||||| .. | ||| NGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC GTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP--LQIPGGRTVAACDLLQSLLHKDQRQRLG-SKADFLEIKNHVFF ||.|| |||.|.. ...||||| ||. .| || | ||| . . || |..| | . ||.. || .. ||.| | .|. | || GTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
|||||||||
Kinase | SGK2.AA | Eta | 95-352 | 46 | 6.2e-106 | 358.24 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-261/261 Sequence Identity: 46% (122 aa) FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEP |.|.||.||| .|||.||.|| . ||.|||.| |.. . |.|. .| .|||| | .|||...|.||..|||||.| |..|| |.| || FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP RARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPF ||||||||| .|. .|| ..|||||| .||||| .|| | |||.||||. . ||.||||||.|.|||.|. | .|||| .| ..|||. | ||| RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF YSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKA---DFLEIKNHVFF . ...| ||| | | .|.. . | ..|||. . . .|..| || EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF |
|||||||||
Kinase | SGK2.AA | S_TKc | 95-352 | 36 | 2.6e-104 | 353.75 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-231/231 Sequence Identity: 36% (98 aa) FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNG--GELFFHLQRERR-- ...|..|||| .||| ... |..| .|.|.. ||. |...| | .||..| | ..||. ..||.|..|..| |.|| .... .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG ----FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR-AVDWWCLGAVLY | | .||||......|. |.||..||.||||||||||| |. ..||||... .||||||.|.||||| .|.. ..||| .| .|| LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY EMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFL---EIKNHVFF ||| | |||. .. .|...|. . |.|... .|.|| ..|.. . .||.| .| EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | SGK2.AA | Alpha | 95-352 | 44 | 1.3e-98 | 333.89 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-259/259 Sequence Identity: 44% (114 aa) FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEP | ||.|.||| .|||.|| || ||.|.|.| | | |. || . |||| . |||. ||||. ||||| | .|.|. .| || FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP RARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPF | |||||.| . .||. ||||||| |..|| ||. ..|||.|||.. ...|| ||||||.|.|||. .|| ..|||| | ||||. | ||| HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF YSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGS-KADFLEIKNHVFF | ....| . | . | |. ...| | .|||. . . .|. | || DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF |
|||||||||
Kinase | SGK2.AA | Pkinase | 95-352 | 31 | 1.7e-90 | 311.77 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 95-352 Range on HMM: 1-293/293 Sequence Identity: 31% (94 aa) FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIM-AERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGG----ELFFHLQ--R . ....||.|..|.| ....|..| .|||.. |... ..|.|.|. .| ..... .||. | |...|... ..|.|..|..|| .|| ... | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR ERRF--LEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHV----VLTDFGLCKEG-VEPEDTTSTFCGTPEYLAPEVLR-KEPYDRAVDWWC ...| | ..||. ...... |.|| .||.|||||||||.| .||. ..||||.| . ..||||||.|.||||.| ..|...||.| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS LGAVLYEMLHGLPPFYSQ------DVSQMYENILHQPLQIPGGRT---------------------VAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFF .| .||||| | |||... | ||...|.. || . . ...|.. ..|.|| .|.. . .|..| .| CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF |
|||||||||
Kinase | SGK2.AA | S_TK_X | 353-419 | 31 | 8.8e-18 | 66.31 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 353-419 Range on HMM: 1-79/79 Sequence Identity: 31% (26 aa) SPINWDDLYH--KRLTPPFNPNVT----GPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSA---------FLGFSYAP . |.||.||. |...||| |... .| |.. |||||| |... .|...|.| .. |.||.| RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
|||||||||
Kinase | SGK2.AA | TyrKc | 95-350 | 20 | 5.2e-14 | 3.9 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 95-350 Range on HMM: 1-280/280 Sequence Identity: 20% (60 aa) FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV--RHPFLVGLRYSFQTP-------EKLYFVLDYVNGGELFFHL ..|..| |..|.| ... | |||.|.. . . .| | ..... .|| .| | .. | |. |. |. .| | .| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMRE-ARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL QRERR-FLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEP-------EDTTSTF--CGTP----EYLAPEVLRKEPY .. |. . . .. .|. |||| |.| ||| |.|.. ...| .||||.... . . ... .| .|||.... . RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF DRAVDWWCLGAVLYEML-HGLPPFYS-----QDVSQMYENILHQ--PLQIPG--------GRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHV . | | | ...|.. | .| . . ....|.. . . | | . . .. | | .| | ||. TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDR----PTFSEIHECF |
|||||||||
Kinase | SGK2.AA | Pkinase_C | 372-421 | 40 | 1.9e-13 | 50.54 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 372-421 Range on HMM: 1-46/46 Sequence Identity: 40% (20 aa) NVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPED .|..| | .||||||.|... . ||. .|||. ..| ||.| ..| QVKSPTDTSNFDPEFTDEPPMDTP---PDWR-MSSGDQEPFRGFTYVNPD |
|||||||||
Kinase | SGK2.AA | Pkinase_Tyr | 95-306 | 24 | 2.2e-09 | 32.39 | Pfam | 1-228 (270) | Show / Hide |
Range on Protein: 95-306 Range on HMM: 1-228/270 Sequence Identity: 24% (57 aa) FDFLKVIGKGNYGKVLLAKRK--SDGAFY--AVKVLQKKSILKKKE--QSHIMAERSVLLKNV-RHPFLVGLRYSFQ-TPEK--LYFVLDYVNGGELFFH |.|..|.|..|.| ... | |. . |||.| | ... . |.| .. .|. .|| .| | | .| |. |. .| | . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKI-MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY LQR----ERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTT-STFCGTPE---YLAPEVLRKEPYDRAVD |.. .... .. .....|.. ||.| |.| ||| |.|......| .||||.. ...|. . |.. .|||... . . | LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD WWCLGAVLYEMLH-GLPP-FYSQDVSQMYENI | | ...|.. | | .. . ...|| | VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI |