Gene SGK1 (Human)
SGK1
Sequence
Protein domains of SGK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | SGK1.AA | SGK | 193-450 | 66 | 7.2e-229 | 714.66 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-283/283 Sequence Identity: 66% (189 aa) FHFLKVIGKGSFGKVLLARHKAE------------------EVFYAVKVLQKKAIL-------KKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKL |.|||||||||||||....||.. . |||.|||||..|. ||||.||||.||||.|||.||||.|.||..|||..|| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ |||.||.||||.|||||||..|.|.|||||||||..||.||||..|.||||||||||||.|||..|||||||||.|..| ||.||||||||||||||.|| YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFF |.||||||||||.|||||.||||||||||...|||||.|.|||..|...|.|..|..||||||..||||.|.||||||.|.|| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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Kinase | SGK1.AA | AGC | 193-450 | 36 | 2.3e-195 | 510.91 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-395/395 Sequence Identity: 36% (147 aa) FHFLKVIGKGSFGKVLLARHK------AEEVFYAVKVLQKKA-ILKKK--EEKHIMSE------------RNVLLKNVK---------HPFLVG-LHFSF |.||||||||||||| |.|.| . . .||.|||.|| |..|| ...|.|.| ||.| | . |||.| ||.|| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTADK--LYFVLDYIN---------GG-ELFYHLQ---RERCFLEPRARFYAAE-------IASALGYLHS-LNIVYRD-LKPENILLDSQGHIVLTDFG |. |. ||||..|.. || |||.||| .|..| |.|||||||| |..|| |||| ..|..|| |||||||||..||| ||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LCKENI--------------------------------------------------EHNSTTSTFCG--TPEYLAPEVLHKQPYDRTVDWWC--LGAVLY ||||.. . . .|.|||| ||||.|||.| |....|||. ||...| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMLYGLPPFYSRN----------TAEMYDNIL------NKPLQLK----------PNITNSARHLLEGLLQKDRTKRLGAKDD------FMEIKSHVFF |||.|.||||. | .||...|. |..... ..... |..|...||.||..||||.... . |||.| .| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | SGK1.AA | Akt | 193-450 | 56 | 3.3e-172 | 554.86 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-264/264 Sequence Identity: 56% (149 aa) FHFLKVIGKGSFGKVLLARHKA-EEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLE | ||||.||||||||.|.. |. ....|| |||.|. |..|.. .|.. |||. |....|||.|.||.||||.||||||.||.|||||||||||.| | | FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNI-LQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE PRARFYAAEIASALGYLHSLNIVYRD-LKPENILLDSQGHIVLTDFGLCKEN-IEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWC-LGAVLYEMLYG .|||||.||| .|...||| ||.||| |||||||.|..||| |||||||||| | .. .| ||||||||||||.| .. ....|||| ||.|.|||..| DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG LPPFYSRNTAEMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKRLG-AKDDFMEIKSHVFF .||||... .|...|.|.|.. . ..| . .. |..|||.||..|||| ...| |||.| .| RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | SGK1.AA | AktR | 193-450 | 44 | 1.4e-129 | 436.76 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-268/268 Sequence Identity: 44% (119 aa) FHFLKVIGKGSFGKVLLARHK-AEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLE ||..|..||| |||| |...| . .|| |.. || | ... ..|. |||.. . ..|||.| ||..||| .||.|...|. |||||.||.... | | FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE PRARFYAAEIASALGYLHSL-NIVYRDLKPENILLDSQGHIVLTDFGLCK-ENIE-HNSTTSTFCGTPEYLAPEVLHK-QPYDRTVDWWCLGAVLYEMLY .||||.|.| || |||. ||.||||||||||||. ||. .||||| | .... . .. .|||||||.|||.. | ......||||..|...|||.. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GLPPFYSRNTAEMYDNILNKP-LQLKPN--ITNSARHLLE-GLLQKDRTKRLG-AKDDFMEIKSHVFF |.||||. |. .|...|..|. .. ... ... .. |.. .||.|. .|||| .. .. ||||| .| GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | SGK1.AA | PKC | 193-450 | 46 | 1.2e-128 | 419.2 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-262/262 Sequence Identity: 46% (123 aa) FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEP |.||||.||||||||.||..| . .||.||| | .|.. | |. || |||||..|| .||| |.|.||. |.||| | .| |. | | |. FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE RARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF .||||||||..|| .||. .|.||||| .|.|||. ||| ..|||.||||. .|||||||||.|.|||.| |.| |||| .| .|||. | .|| HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF YSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDD----FMEIKSHVFF . |. ..|... .. | ....|...|. .||||.. . ...|..| || HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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Kinase | SGK1.AA | PKA | 193-450 | 44 | 2.6e-126 | 425.95 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-263/263 Sequence Identity: 44% (118 aa) FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVG-LHFSFQTADKLYFVLDYINGGELFYHLQRERCFLE | .....|.||||.| |.||| . .|| |.| | | . | . |...|.|. |.|.||||.| . ..||....||.|..|..|||.|..|.....| . FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNI-LQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN PRARFYAA-EIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ-PYDRTVDWWCLGAVLYEMLYGL | |.|||| .| .|| ||||.||.||||||||||.|..||| .|||| |. .. |.| ||||||||||.. .. . ||||.|| . |||| | PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY PPFYSR--NTAEMYDNILNKPLQLKPNITNSA---RHLLEGLLQKDRTKRLGAKD-DFMEIKSHVFF |||| .....|. |.| .. ..... | ..|.. |||.|.|||.| .. . || | .| PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | SGK1.AA | RSK | 196-450 | 44 | 2.4e-125 | 422.72 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 196-450 Range on HMM: 1-278/278 Sequence Identity: 44% (124 aa) LKVIGKGSFGKVLLARHK---AEEVFYAVKVLQKKAILKK-KEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC--- ||| |.|..||| | | . . . ||.|||.|. | .. | .| | |||.|. .|||.| || .||| .||| ...|..|||||.|||.|.. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDS---QGHIVLTDFGLCKE-NIEHNSTTSTFCGTPEYLAPEVLH---KQP-YDRTVDWWCLGA | | .|.||.|||..|. .||.. |..|||||||||.|. .|||.|||||.||. ...||. | |||.| ||.|||.| .| .|. .||| ||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV VLYEMLYGLPPFYS---RNTAEMYDNILNKP--LQLK--PNITNSARHLLEGLLQKDRTKRLGA-KDDFMEIKSHVFF ..|||| | |||.. | .| ..|... | .. ..... |..|. ..|..| ||||. ..| |||.| .| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | SGK1.AA | RSK-Unclassified | 193-450 | 41 | 4.2e-113 | 356.71 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-283/283 Sequence Identity: 41% (118 aa) FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQ--RERCFL | . ||.|.|||| | | | . || |||.|. ..... | .| |.|.. .||| | | .|||| |.|| ...| ||..| ||| .|.|| FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMAT-TNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFC EPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKEN---------------------IEHNSTTSTFCGTPEYLAPEVLHKQPY | ..||||.|. || ||| . ..||||||.||.|. ||. ||||.| .. ..| . | |||| ||||||.. EDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGH DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKRLGAKDD-FMEIKSHVFF . |||| || |.|||| |.||.| |. |.. ||. ..... | | .| |. |||. ||||.| .|| | || TKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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Kinase | SGK1.AA | p70 | 193-450 | 42 | 4.6e-112 | 378.61 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-299/299 Sequence Identity: 42% (126 aa) FHFLKVIGKGSFGKVLLARHKA---EEVFYAVKVLQKKAILK-KKEEKHIM-------------------------SERNVLLKNVKHPFLVGLHFSFQT | |||.||| .|||.. | . . || |||.| |. | | |||. | |||||.. ||..||| FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNI-LEEVKHPFICDLHYAFQT ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNST----------TSTFC ||| .|.|. |||||.|| |. ..| |.||..|| ||..||.. |.||||||||..|..|||.|||||||||| |. . | ||| NGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC GTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP--LQLKPNITNSARHLLEGLLQKDRTKRLG-AKDDFMEIKSHVFF ||.|| |||.| . ... |||| ||. .| || | ||| | .. | || |.| | |...| |. || .. |.|.| .| .|..| || GTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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Kinase | SGK1.AA | S_TKc | 193-450 | 38 | 1.8e-108 | 367.56 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-231/231 Sequence Identity: 38% (104 aa) FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYING--GELFYHLQRERC-- ...|..||||.|||| ..||| .|.|.. .||..|...| | .||..| |. .||. |.||.|..|..| |.|| .... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG ----FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR-TVDWWCLGAVLY | | .||||...|..|| |.||..|..|||||||||||. || ..||||... .||||||.|.||||| .|.. .||| .| .|| LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY EMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFM---EIKSHVFF |||.| |||. . ..|...|. . .|.......|||| .||..| . . .||.| .| EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | SGK1.AA | Eta | 193-450 | 46 | 1.2e-106 | 360.57 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-261/261 Sequence Identity: 46% (122 aa) FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEP |.|.||.||||||||.||..| . ||.|||.| .|.. . | |. .| ||||| || .||| |.|.||..|.|||.| ...|| | | || FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP RARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF ||||||||. .|| .|| ...||||| .||||| .|| | |||.||| | .. ||.||||||.|.|||.|. . | .|||| .| ..|||. | ||| RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF YSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAK---DDFMEIKSHVFF | .... ||. . . | .| . . | .||||. .. .|..| || EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF |
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Kinase | SGK1.AA | Pkinase | 193-450 | 33 | 1.2e-91 | 315.61 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 193-450 Range on HMM: 1-293/293 Sequence Identity: 33% (101 aa) FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIM-SERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGG----ELFYHLQ--R .|....||.||||.| ...|| .. .|||.. |. . ..|.. |. || .... .||. | |. .|.. |..|.|..| .|| .|| ... | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR ERCF--LEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHI----VLTDFGLCKEN-IEHNSTTSTFCGTPEYLAPEVLH-KQPYDRTVDWWC ..|| | ..||. .|...| |.|| .|..|||||||||.|..||| ..||||.| . .|| ..||||||.|.||||. |.|.. ||.| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS LGAVLYEMLYGLPPFYSR------NTAEMYDNILNKPLQLKPNIT---------------------NSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFF .| .||||| | |||... . .|...|. .|| . .........|.|| .||.. ...|. | .| CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF |
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Kinase | SGK1.AA | S_TK_X | 451-520 | 33 | 7.1e-20 | 73.28 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 451-520 Range on HMM: 1-79/79 Sequence Identity: 33% (28 aa) SLINWDDLIN--KKITPPFNPNVS----GPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAA-------EAFLGFSYAP . |.||.| | |.|.||| |... .| |.. ||||||||.. .||. ...|. . . . |.||.| RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM----LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | SGK1.AA | TyrKc | 193-448 | 20 | 7.6e-14 | 1.16 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 193-448 Range on HMM: 1-280/280 Sequence Identity: 20% (61 aa) FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKN-VKHPFLVGLH-FSFQTA------DKLYFVLDYINGGELFYHLQ ...|..| | ||.| ... | . |||.|.. | .. .|.| ... | .|| .| |. | . |. |. | .| | .|. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR RERC-FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEH-------NSTTSTF--CGTP----EYLAPEVLHKQPYD . | . . .. ||. |||| |.. ||| |.|....... .||||... .. ... .| .|||.. . . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT RTVDWWCLGAVLYEML-YGLPPFYS-----RNTAEMYDNILNKPLQLKPNI---------TNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHV | | | ...|.. || .| . . .|.. .. . .| . . . . | .| | ||.. TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP----TFSEIHECF |
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Kinase | SGK1.AA | Pkinase_C | 470-522 | 32 | 3.2e-12 | 46.26 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 470-522 Range on HMM: 1-46/46 Sequence Identity: 32% (17 aa) NVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPT .|..| | ..||||||.||.. . . . . ... |.| ||.| .| QVKSPTDTSNFDPEFTDEPPMDTP------PDWR-MSSGDQEPFRGFTYVNPD |
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Kinase | SGK1.AA | Pkinase_Tyr | 193-340 | 25 | 3.1e-08 | 28.5 | Pfam | 1-159 (270) | Show / Hide |
Range on Protein: 193-340 Range on HMM: 1-159/270 Sequence Identity: 25% (42 aa) FHFLKVIGKGSFGKVLLARHK------AEEVFYAVKVLQKKAILKKKE--EKHIMSERNVLLKNV-KHPFLVGLHFSFQ-TADK--LYFVLDYINGGELF .|.|..|.|.||.| ... | .| |||.| | ... . |.| .. .|. .|| .| |. . .| |. | .| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV--AVKML--KEGAMHEQNCREDFMREAKI-MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL YHLQR----ERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCK .|.. .. . .. ....||... ||.| |.. ||| |.|....... .||||.. DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |
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Kinase | SGK1.AA | Pkinase_Tyr | 359-404 | 25 | 6.457225 | 0.34 | Pfam | 181-228 (270) | Show / Hide |
Range on Protein: 359-404 Range on HMM: 181-228/270 Sequence Identity: 25% (12 aa) LAPEVLHKQPYDRTVDWWCLGAVLYEMLY-GLPP-FYSRNTAEMYDNI .|||... . | | | ...|.. | | .. .|.|. | MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI |