Gene QIK (Human)

QIK

Species: Human
Alias: SNF1LK2, DKFZp434K1115, QIK, SIK2, LOH11CR1I, KIAA0781, Hs.42676
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 11q23.1,

Classification

Group: CAMK
Family: CAMKL
Subfamily: QIK

Sequence

Name Sequence Type Origin Length Description Download
QIK.NA RNA Sugen Kinome 5730 None Fasta, JSON
QIK.AA Protein Sugen Kinome 926 None Fasta, JSON
QIK.kin_dom Protein Kinase Domain Sugen Kinome 252 None Fasta, JSON

Protein domain

Protein domains of QIK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase QIK.AA QIK 20-271 72 5.70000000001e-210 703.85 In-house 1-272 (272) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-272/272
Sequence Identity: 72% (198 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGR------
|||| |.||||||||||.|||||||.||||||||||||. ||.|.||||||||||.|||||||||||||..|.|.||||..|||.||||..|||      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLD
              ..|.||||.||||.|||.||| |.||||||||||.|||||||||||||||.|.||.|.||.||||||||||||.|||..|.||..|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

IWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
||||||||||||||||||||.||. ||||||.|.||||.|||.|||||||.|||.||..|.||.||..|.||
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase QIK.AA CAMKL 20-271 47 6.5e-167 536.83 In-house 1-297 (297) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-297/297
Sequence Identity: 47% (143 aa)

YDIEGTLGKGNFAVVKLGRH-RITKTEVAIKIID--KSQLDAVNLEK-----------IYREVQIMKMLD---HPHIIKLYQVMETKSM------LYLVT
|.|. |||||.|..|||..| |.|...|||||||  | ..| ... .           |.||.||||||.   ||.|||||.|.||...      .|||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAKNGE--IFDYLANH----GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNM--NIKIADFGFGNFFKS-----GELLATWCGSPPYA
||. .||   |||. .|    ||. |.|||| |.||.|||.||| ..|||||.|.||.|||.|.  ||||.||||.|...      |..| |.||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVFEG--QQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLP---------ILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
|||.|.|  ..|.||. ||||.||.||..|||.||||..|..          ...... ....|.|..| ||..|||.||. .|.|| || ||..|.||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase QIK.AA AMPK 20-271 51 4.2e-151 451.81 In-house 1-254 (254) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-254/254
Sequence Identity: 51% (131 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNL-EKIYREVQIMKMLDHPHIIKLYQVM-ETKSMLYLVTEYAKNGEIFDYLANHGRLNES
| |. |.|.| |  ||.| | .|...|||||..|  .  .   |.| ||..|.|.. |||||.||.|  ||.. ...|.||. .|| ||| . ||||.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPF
||.| | ||.|.|.|||  .||||||| |||||| |.||||.|||  |  | ||.| | |||| |||||. .|. |.||. |||| ||.||...|| |||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
| .  | | .....|.. ||.|.|.... ||..||  || ||.|| .|..|.| 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase QIK.AA MARK 20-271 49 8.4e-151 496.01 In-house 1-262 (262) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-262/262
Sequence Identity: 49% (130 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDA-VNLEKIYREVQIMKMLDHPHIIKLYQVME--TKSM-LYLVTEYAKNGEIFDYLANH--GR
| .  |.|.|..|.|||..|. |...|||||..| .|.   ......||..|||.||||.||||..|.|  |..  .||. ||| .|| .||. .|  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNM--NIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLV
| |.|||| | ||.||| ||| . |||||.|.||.|.| |.  ||||.||||.. ...|..| | ||.|||.|||.|... |.||  ||||.|||||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGALPFDGPT--LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
|| .|||| |  .  |....| |...||...| .|..||.|.|...|..| || .| .|.||
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase QIK.AA CAMK 25-271 30 4.3e-142 461.03 In-house 1-425 (425) Show / Hide 
Range on Protein: 25-271
Range on HMM: 1-425/425
Sequence Identity: 30% (131 aa)

TLGKGNFAVVKLGRHRITK------------TEVAIKIIDKSQLD--------------------------AVNLEKIYREVQIMKM-------LDHPHI
|||.|.|..|||..|. |.            ..||||||||..|.                          ........||..|||.       ||||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYQVME------------TKSM--------LYLVT---EYAKNG----EIFDYLANH---------------GRLNESEARRKFWQILSAVDYCHGRK
||||.|.|            | |.        .|.|.   ||. .|    ..|||.  |               ||..|.|||| |.||.|||.||| ..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKAENLLLDNNM-----------------NIKIADFGFGNFFKS------------------------GELLATWCGSPPYAA-PEVFEG-----
||||||| ||.|||.|.                 ||||.|||| |.|..                        |... |.||.|.|.| |||..|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QQYEGPQLDIWSMGVVLYVLVCGALPFDGP-------------TLPILRQRVLEGRFR-IPYFMSE-----------------------DCE
        ..| ||. |.||.||.||...|| .||.|.             ... | .....|... .|...|.                       .| 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

HLIRRMLVLDPSKRLTIAQIKEHKWM
.|||.||. ||.||.||.|...|.||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase QIK.AA NuaK 20-271 47 1.6e-131 348.24 In-house 1-252 (252) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-252/252
Sequence Identity: 47% (120 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQL-DAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESE
|... ||||| .  |||.. . |  ||||| | |.   |   . .| ||..||  |.|||||. | | | |. . .| |||  || .||. . ..| | |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFD
||. | || ||| |||  .|.||||| || |||.| |.||||||  |... ...| | |||| || ||. .|| |.||  | ||.||.||..| | .|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
|     | . . .|... |   |. |. ||| ||  .| .| || .| .| |.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase QIK.AA NIM1 20-271 43 5e-116 342.33 In-house 1-258 (258) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-258/258
Sequence Identity: 43% (111 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIID--KSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNES
| . | .| |||  |||| |  ||  |||||.|  |  .|.  .    ||.| |  . || |..|| | || . ..||.|||  || . .  . | | | 
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

EARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKS----GELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCG
..   | ||.|||   | | |||||.|||| ..  |  .|..||||    |     .. | | |||||||||| |  . | |.  |.|  |. ||  . |
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

ALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
  ||  .| | .   .|.| . || . |. |  |||.||  .|  | || |.. | ||
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase QIK.AA BRSK 20-271 50 6.6e-111 374.75 In-house 1-254 (254) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-254/254
Sequence Identity: 50% (128 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLD--AVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNES
| .| |||||    |||| | .|   |||||| |  |      | |. ||. |||. ||||..|.| | |.|  |||. |.   || ||||   |||   
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPF
|||. | || ||.|.|| . | ||||| ||||||.  |||||||| .     . .| | |||| || |||  | .| | . |.|| ||.|| |  |||||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
|   |  |  .|  | | .| |   ||  | | |.  ||.||.....|..| | 
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase QIK.AA S_TKc 20-271 36 6.7e-104 352.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKN--GEIFDYLANHGR----
|.|  ..||| |..|...||. |. .||||||.         |.|.||.||.|. .||.|.||| |... . ||.|.||. .  |. |||. ..||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLV
  ..| .||. ..||..|..||| ..|.||||| ||.|||.  .|||.|||.  ..       | ||.| | ||||.   .| ..  |.|| |..|| ..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

CGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKE-------HKWM
||  ||.  ..  . ....          |... ..||..|. ||.||.|. .. .       | |.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase QIK.AA TSSK 20-271 37 2.1e-103 340.23 In-house 1-289 (289) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-289/289
Sequence Identity: 37% (107 aa)

YDIEGTLGKGNFAVVKLGRHRITKTE----------------VAIKIIDKSQLDAVNLEK-IYREVQIMKM-LDHPHIIKLYQVMETKS-MLYLVTEYAK
|. . ..|.|..| |...... .| .                |||||||.    . .|.| . || |||.. |.||.||..|.  || . . |.| ||| 
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

NGEIFDYLANH------GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGE------LLATWCGSPPYAAPEVF
.|  ..|  ..      |.| |..||. |.|. |||.|||.. .|||||| ||.||| . |||..||||.. .....      |. | |||  |||||..
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

EGQQYEGPQLDIWSMGVVLYVLVCGALPFDG--PTLPILRQRVL--EGRFRI--PYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
 |  | . . |.|||||.||..||| .|||     .. . ...   .  |..    . |..| .|||.|| ..|..|..| .|..| ||
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase QIK.AA Pkinase 20-271 35 1.8e-99 341.6 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-293/293
Sequence Identity: 35% (104 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYR--EVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNG----EIFDYLA--NH
| |....|.|.|..|....|. |  .||.|||.|.  .   ..   |  |.||||.|.||.|..|| ..|.|. .|.|.||. .|    . |||.   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNI----KIADFGFGNF--FKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM
|..   | |... ..|||....||| ..|.||||| ||.|.|||..|    ||.|||.  .    ... . | ||.|.|.||||  |.|| ||  |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLYVLVCGALPFDGP------TLPILRQRVLEGRFRIPYF---------------------MSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
|..|| ..|| .||.|       .   . .|....... ...                     .||.| ..|...| .||.||.|..||..|.|.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase QIK.AA SNRK 20-271 44 1.3e-94 310.25 In-house 1-254 (254) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-254/254
Sequence Identity: 44% (112 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGR-LNESE
||.| |||.| |||||| ||  |   ||.|.||| ..|.|   ....||. ||.  || |..|| |..|.  |||. |    ....||.  | . |.|. 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMN-IKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPF
||. | ||. |.|||| ...|||||| || .  . .  .|. |||| | |. || | | |||  |.|||.  | .|. | .||||.||.||.|||| .||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

DGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
.         .... .. .|  .|..|  || .||| || || .. .|..| |.
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase QIK.AA Pkinase_Tyr 20-162 33 2.4e-28 96.62 Pfam 1-156 (270) Show / Hide 
Range on Protein: 20-162
Range on HMM: 1-156/270
Sequence Identity: 33% (52 aa)

YDIEGTLGKGNFAVVKLGRHR----ITKTEVAIKIIDKSQLDAVN--LEKIYREVQIMKML-DHPHIIKLYQVME-TKSM--LYLVTEYAKNGEIFDYLA
  .  .||.|.| .|..|. .     ||..||.|.. | . .  .  .|.  ||..||| | .||.|..|| |    .    .|.|.||...|   ||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NH----GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFG
.|    ..|. ..     ||| .. .| . ....|||| | | |...|. .||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase QIK.AA TyrKc 20-271 24 8.3e-25 89.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-271
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKML--DHPHIIKLYQVMETK-------SMLYLVTEYAKNGEIFDYLAN
   . .|| |.| .| .|. .   ..||.| . ..      .| ..|| .||..|  .||.|..|| |  ..         |..|.||...|   ||| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HGR-LNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSG-------ELLATW---CGS--PPYA--APEVFEGQQYEG
|.. |. ..     ||| .  .| | ....|||| | | |...|  .||.|||   . ...       .   .    .|    |.   |||..    .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-T

PQLDIWSMGVVLY-VLVCGALPFDG-----PTLPILRQRVLEGRFRIPYFM---------SEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM
.. |.|| ||... ..  |. |  |      .   ....| .|. . .            ...   ....    ||..| | ..|  |. .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
UBA_CAMKL QIK.AA UBA_CAMKL 297-334 39 3.8e-14 48.82 In-house 1-41 (41) Show / Hide 
Range on Protein: 297-334
Range on HMM: 1-41/41
Sequence Identity: 39% (16 aa)

NEQVLRLMHSL--GIDQQKTIESLQNKSY-NHFAAIYFLLV
.|.....| ..  |.| ...||||.| .| ||  |.|.||.
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL