PSKH2

Species: Human
Alias: PSKH2
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 8q21.3,

Classification

Group: CAMK
Family: PSK

Sequence

Name Sequence Type Origin Length Description Download
PSKH2.NA RNA Sugen Kinome 1158 None Fasta, JSON
PSKH2.AA Protein Sugen Kinome 385 None Fasta, JSON
PSKH2.kin_dom Protein Kinase Domain Sugen Kinome 258 None Fasta, JSON

Protein domain

Protein domains of PSKH2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PSKH2.AA PSK 63-320 74 9.90000000001e-221 712.61 In-house 1-258 (258) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-258/258
Sequence Identity: 74% (192 aa)

YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVR
||||||||.||||||||||...|..|.|||..||..|||||.|..||..||||.|.||.||||.|||.|.||||||.|||||.|||..|.|.||||||.|
YDIKALIGKGSFSRVVRVEHRVTRQPYAIKMVETKCREGREFCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDATR

ILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPF
.||||.||.||||||.||||.||||||||||||.||||.||||||||..|||.||.|||.||||||||||||||||||..|||||.|||.|.|.||..||
VLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIMPF

DDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV
||...|||||.||.|||||.|.||||.||||||||||||....|.||.|.||..||||
DDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV

Kinase PSKH2.AA CAMK1 63-320 41 1.2e-128 376.11 In-house 1-276 (276) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-276/276
Sequence Identity: 41% (117 aa)

YDIKALIGTGSFSRVVRVEQKTT---KKPFAIKVME-TREREG-----REACVSELSVLRRV---SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLI
| ..  ||.|.|| |.....| |   .|..|||...  .  ..     .||   |......|   .|  |... |..|... .|.|||| |||||||| .
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

AQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKIL--ITDFGLAYSGKKSG-DW-TMKTLCGTPEYIAPEVLLR---KPYTSAV
  |..||.||..| . ... . |.|.. | || ||||||||| . |.|||   | ||||.   |. . |  .||| ||||.|.||||| .   |||  |.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLS---KIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKAC

DMWALGVITYALLSGFLPFDDES-QTRLYRKILKGKYNYTGEPWPSISHL-AKDFIDKLLILEAGHRMSAGQALDHPWV
|||  ||||| || |. || ||. .  |..||.|..|..    | .||   ||||| ..| ..   | .. |.|.|||.
DMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase PSKH2.AA CAMK 68-320 24 8.3e-117 378.08 In-house 1-425 (425) Show / Hide
Range on Protein: 68-320
Range on HMM: 1-425/425
Sequence Identity: 24% (103 aa)

LIGTGSFSRVVRVEQK-TTK-----------KPFAIKVMETR----------------------------EREGREACVSELSVLRR-------VSHRYI
 .|.|||. | ....| ||.           . .|||.....                            . . |.   .|......       ..|. |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLMEIFE------------TEDQ--------VYMVM---ELATGGEL----FDRLIAQGS---------------FTERDAVRILQMVADGIRYLHALQ
..| |..|            | ..        .||||   |...||||    ||.....|.               ||||.| |. . ......|.| . 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ITHRNLKPENLLYYHPGEES--------------KILITDFGLAYSGKKSGDWT----------------------MKTLCGTPEYIA-PEVLLR-----
| || |||||.|. . ...|              .| |.|||.|   ... . .                      ||| ||||||.| ||||..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KPYTSAVDMWALGVITYALLSGFLPFDDE-------------SQTRLYRKILKGKYNYTGEP------------WPSISHL--------AK
         ..|. ..|||..|||.|..|.|..||...             .. .|..||.||||..  ..            | .||          .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFIDKLLILEAGHRMSAGQALDHPWV
|.| |.|  .  .||.. |.|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase PSKH2.AA RAD53 63-320 33 3.9e-100 298.98 In-house 1-305 (305) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-305/305
Sequence Identity: 33% (102 aa)

YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMET--------REREGREACVSELSVLRRVSHRYIVQLMEIFET-EDQVYMVMELATGGELFDRLIAQG
|..   .|.| |. | ..  |.| . .|||  ..        ...  ..   .|. .|....|. |... .||.| ....|||.||.||||||.......
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

S----FTERDAVRIL-QMVADGIRYLHALQITHRNLKPENLLYYHPGEES---------------KILITDFGLAYSGKKSGDW-TMKTLCGTPEYIAPE
     |.| .. ... ||. |...||| . |.|| ||||| |. |..||                .| ||||||.   | .|.   |||.|||| | |||
RCQMGFDEDTCKYYFYQMC-DAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS---KFVGEGSFMKTMCGTPQYVAPE

VLLRK---------------PYTSAVDMWALGVITYALLSGFLPFDDE-----SQTRLYRKILK-GKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSA
|.. |                ||..||.| .|.|.| .|.|..||.|.     . . |. .|.. |||... . | .||  |||.|...|...  .| ..
VITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTI

GQALDHPWV
 .|| ||| 
DEALNHPWM

Kinase PSKH2.AA S_TKc 63-320 33 1.4e-96 328.13 SMART 1-231 (231) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATG--GELFDRLIAQGS------
|.|  .|| |.|..| ..  | |.. .|||..        |   .|...|..  | .||.| ..|.. | .|||||.. |  |.|||..  .|.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTS-AVDMWALGVITY
|.| .| .... ..... |.| ..| || |||||.|  .      | |.|||||           .|.||||.|.|||||   .|.  ..|.|..|.| |
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALD-------HPWV
 .|.|  ||.   . ....||.              |. |||||.|.|  .  .|..| .||        |||.
EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase PSKH2.AA MLCK 63-320 34 4e-94 248.27 In-house 1-257 (257) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-257/257
Sequence Identity: 34% (92 aa)

YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQG-SFTERDAV
|.|. ..| | |. |.|...|.|.| .| |.. .|... .|  . | ....   |. ..|. . ||| ... |.||. .|||||.| ....  .|||. .
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI

RILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAY----SGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLS
...  . .|....|  .| | .||||| ..  . . ..| | |||||      .||      |...||||..||||  . | . . |||..|||.| |||
HYMRQICEGVHHMHWQNIVHLDLKPENIMCQTR-TSHQIKIIDFGLARKYDPDEKK-----VKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLS

GFLPF--DDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV
|. ||  |.. .|  . ....... .  | .. ||  |||||..||. .   ||.| ..|.||| 
GLSPFMGDNDRET--MNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL

Kinase PSKH2.AA DCAMKL 63-320 36 8.1e-91 282.74 In-house 1-279 (279) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-279/279
Sequence Identity: 36% (102 aa)

YDIKALIGTGSFSRVVRVEQKTTK-KPFAIKV-----------------METREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGG
|.| ..|| | |. |  . ...|. . .| |.                  . |   | |  . .|.|......| .|.||.| ..||.. |.|||...||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYH--PGEESKILITDFGLAYSGKK-SGDWTMKTLCGTPEYIAPEVLLRKPYT
 ||| ..  . ||||||....  ..  ..||| . | || .|||||| .    | |  .   |||||   ..  |   . | |||| |.|||.|  . | 
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSLKLCDFGLACHVNGDFG--PLYTVCGTPTYVAPEILMETGYG

SAVDMWALGVITYALLSGFLPFDDE--SQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV
  ||.||.|||.|.|| || ||  .  .|..|  .|. ||...    |  ||  ||| | ..|  .   | .|.| ..||||
CKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV

Kinase PSKH2.AA CAMK-Unique 63-320 24 2.9e-86 284.75 In-house 1-363 (363) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-363/363
Sequence Identity: 24% (90 aa)

YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMET--REREGREA------------------CVSELSVLRRVSHRYIVQLMEI----FETED-------
|.   .||.|.|. | ..  ..|.| .|.|. .    ... . .                     |......|.|  |..|...    |....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------QVYMVMELATGGELFDRLIA--------------------QGSFTE--RDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGE-----
          |.|||...||.||| ...                    ||.|.|  .|. .| | ..  . |.| ..| ||.||.||.... ..      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------ESKILITDFGLAYSGKKSGDWT-MKTLCGTPEYIAP--------------EVLLRKPYTSAV----DMWALGVITYALLSGFLPFDDESQT-
         ..| ..||||.     .   . |.| ||||.|.||              ||. . .| . .    | |.||||.| .|.| .||| |.   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------RLYRKILKGKY-NYTGEPWPS---ISHLAKDFIDKLLILEAGHRMSAGQALDHPWV
       .....|.||.| |.  . | .   ||  ||||..... ..  || || ..|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase PSKH2.AA CAMKL 63-320 30 3.6e-86 274.98 In-house 1-297 (297) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-297/297
Sequence Identity: 30% (94 aa)

YDIKALIGTGSFSRVVRVEQ-KTTKKPFAIKVME---TREREGREA------------CVSELSVLRRVS---HRYIVQLMEIFETEDQ------VYMVM
|.|   .|.|||. |   .  .||..  |||...   .....  ..               | . .....   |  |..|.|..||..       .|.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELATGGE--LFDRLIAQ----GSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA--YS-G-KKSGDWTMKTLCGTPE
|.. |||  |||.....    |...|..| |. . . ... |.| . | || .||||.|  . | . .| |.|||..  |  . ...|. ..|| ||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQ-KLKTFCGSPP

YIAPEVLLR--KPYT-SAVDMWALGVITYALLSGFLPFDDE--------SQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALD
| |||....  |||   .||.|..||| ||.. | |||||.         . .||.|| .| |...  .|...|  ..|.| |.|     .|... | . 
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HPWV
|||.
HPWM

Kinase PSKH2.AA Pkinase 63-320 32 7.8e-84 289.61 Pfam 1-293 (293) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVS-----ELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGG----ELFDRLI--A
| |.  || |||..| .   | | | .|.|... | .|  . ...     |.....|..| .||.| ..||..| .|||||.. ||    .|||..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

QGSF--TERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEE-SKILITDFGLA--YSGKKSGDWTMKTLCGTPEYIAPEVLL-RKPYTSAVDM
.|.|  .|... ...  .. |. |.|.  | || |||||.|. . |.  ... |.|||||  ..     .  |.|.||||.|.||||.. ...|...|||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WALGVITYALLSGFLPFDDE------SQTRLYRKILKGKYNYTGEPWPSIS-----------------HLAKDFIDKLLILEAGHRMSAGQALDHPWV
|..|.| | .|.| .||...      .|  ....|..... .  . | |||                   .||||...| .    | .| |.| |||.
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase PSKH2.AA RSK 65-320 31 3e-78 266.27 In-house 1-278 (278) Show / Hide
Range on Protein: 65-320
Range on HMM: 1-278/278
Sequence Identity: 31% (87 aa)

IKAL--IGTGSFSRVVRVEQKTTKKPFAIKVMETREREGR----EACVSELSVLRRVS-HRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGS---
.| |  .| |... . ..... |.. .| || . ...  |    . .  | ..| |.  |  ||.| . |.||. .|..||.  |||||..|  ...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYH-PGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL---RKP-YTSAVDMWALG
|.|..|  ..  ..  ...|| ..| || ||||| || .   .|  | .||||..  .. .    ..| |.| ||.|||.|    ..  .. |.| | ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VITYALLSGFLPFDD---ESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMS-----AGQALDHPWV
|. | .|.|..||     ...  . ..|.|||.. |.. |...|. |||.| |.|  .   | .     | . ..||| 
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase PSKH2.AA Ciliate-E2 63-320 22 1.9e-75 257.0 In-house 1-365 (365) Show / Hide
Range on Protein: 63-320
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

YDIKALIGTGSFS-----RVVRVEQ------------------KTTKKPFAIKVMETREREGREACVSELS-------------VLRRVSHRYIVQLMEI
|..  .||.|.|.     .| .| .                  |...| .|.|.|. .. |  .   ...              .|....| .|... | 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TEDQVYMVMELATGGELFDRLI------------AQGSFTERDAVRILQMVAD---------------GIRYLHALQ-ITHRNLKPENLLYYHPGE
|.  ... .|.|||.. ||.|||...            . ..|||. . .| . ...               ...|||    | ||..||||.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

ESKILITDFGLAY--------------SGKKSGDW-----------------TMKTLCGTPEYIAPEVLLRKP---------YTSAVDMWALGVITYALL
   | |.||||.               ....                     . .|.||||.| |||.| .|.         |. ..|.|.|||| | .|
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

SGFLPFDDESQTRLYRKILKGKYNYTGE--------------PWPSISHLAKDFIDK----LLILEAGHRMS-AGQALDHPWV
.| .||        ...|...|...  .               | ..|  .||.| |    .|  .   |.. . |.|.||| 
FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase PSKH2.AA Pkinase_Tyr 63-184 24 7.9e-14 47.46 Pfam 1-137 (270) Show / Hide
Range on Protein: 63-184
Range on HMM: 1-137/270
Sequence Identity: 24% (34 aa)

YDIKALIGTGSFSRVVRVEQK----TTKKPFAIKVM--ETRERE-GREACVSELSVLRRV-SHRYIVQLMEIFE-TEDQ--VYMVMELATGGELFDRLIA
  .   .| |.| .|.. . |     || | |.|..   . ...  ||.  .|.....   .|  ||.|. .    ...  .|.|||.. .| | | | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----QGSFTERDAVRILQMVADGIRYLHALQITHRNL
    ....|  | . . . .|.|  ||.. .. || |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase PSKH2.AA TyrKc 63-296 19 1.2e-13 -2.2 SMART 1-280 (280) Show / Hide
Range on Protein: 63-296
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRV--SHRYIVQLMEIFETE-------DQVYMVMELATGGELFDRLIAQG
   .  .| | | .|.. . |    . |.|..       ||.  .|.......  .|  ||.|  .  ..       .....|||.. .| | |.| . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

S-FTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKS------GDWTMKTL--CGTP----EYIAPEVLLRKPYT
  .. .| . .   .|.| .|||  .. || |   | |. ...    . |.||||.  ..        .|  .|.   .|         |||..  . .|
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

SAVDMWALGVITYALLS-GFLPFDD-----ESQTRLYRKILKGKYNYTGEP--------------------W-------PSISHLAKDF
.. | |. ||  . ... |  |  .      | ....... .|..    .                     |       |. | . ..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase PSKH2.AA Pkinase_Tyr 230-277 27 1.289308 2.71 Pfam 182-232 (270) Show / Hide
Range on Protein: 230-277
Range on HMM: 182-232/270
Sequence Identity: 27% (14 aa)

APEVLLRKPYTSAVDMWALGVITYALLS-GFLP-FDDESQTRLYRKI-LKG
|||..  . .|.. | |. ||  . ... |  | . . | ...|..|  .|
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG