Gene PSKH1 (Human)

PSKH1

Species: Human
Alias: PSKH1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 16q11-q22.1,

Classification

Group: CAMK
Family: PSK

Sequence

Name Sequence Type Origin Length Description Download
PSKH1.NA RNA Sugen Kinome 3505 None Fasta, JSON
PSKH1.AA Protein Sugen Kinome 424 None Fasta, JSON
PSKH1.kin_dom Protein Kinase Domain Sugen Kinome 258 None Fasta, JSON

Protein domain

Protein domains of PSKH1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PSKH1.AA PSK 98-355 81 4.5e-225 726.72 In-house 1-258 (258) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-258/258
Sequence Identity: 81% (209 aa)

YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATR
||||||||.||||||||||||.|||||||||.|||.|||||.||.||..||||||..||||.||||||.|||||||.|||||.||||.|||.||||||||
YDIKALIGKGSFSRVVRVEHRVTRQPYAIKMVETKCREGREFCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDATR

VLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPF
||||||||.||||||.|||||||||||||||||..|||.|||||||..|||..|..||||||||||||||||.|||||.||||||.|||||||.||.|||
VLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIMPF

EDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV
.||.||||||.||.|||.|.|.||||||.|||||||.||....|.||||.||..||||
DDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase PSKH1.AA CAMK1 98-355 45 3.5e-140 410.24 In-house 1-276 (276) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-276/276
Sequence Identity: 45% (126 aa)

YDIKALIGRGSFSRVVRVEHRAT---RQPYAIKMIE-TKYREG-----REVCESELRVLRRV---RHANIIQLVEVFETQERVYMVMELATGGELFDRII
| ..  ||||.|| |....|. |    ..||||.|.  |  ..     .|  | |. ....|    | |||.. |..|. . .|.|||| |||||||||.
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

AKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKII--ITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVR---KPYTNSVDM
 ||..||.|| .. . .|. | |.|..|| |||||||||||| .  ||||   | ||||.   . ... |||| ||||.|.||||| .   ||| ...||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN-LMKTACGTPGYVAPEVLECKKDKPYDKACDM

WALGVIAYILLSGTMPFEDDN-RTRLYRQILRGKYSYSGEPWPSVSNL-AKDFIDRLLTVDPGARMTALQALRHPWV
|  ||| |||| |  || |.|    |...|....| .    | ..|.  |||||  .|.|||  | |. |.|.|||.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase PSKH1.AA CAMK 103-355 27 3.8e-125 405.45 In-house 1-425 (425) Show / Hide 
Range on Protein: 103-355
Range on HMM: 1-425/425
Sequence Identity: 27% (117 aa)

LIGRGSFSRVVRVEHRATR------------QPYAIKMIETK----------------------------YREGREVCESELRVLRR-------VRHANI
 .|||||. | ...|. |             | .|||.|..|                              . |.  ..|......       ..| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLVEVFE------------TQER--------VYMVM---ELATGGEL----FDRIIAKGS---------------FTERDATRVLQMVLDGVRYLHALG
|.| ||.|            | ..        .||||   |...||||    ||.|...|.               ||||.| |. . ....|.|.| ..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ITHRDLKPENLLYYHPGTDS--------------KIIITDFGLASARKKGD----------------------DCLMKTTCGTPEYIA-PEVLVR-----
| ||||||||.|. . ..||              .| |.|||.|   ..|.                      . .||| ||||||.| |||| .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KPYTNSVDMWALGVIAYILLSGTMPFEDD-------------NRTRLYRQILRGKYSYSGEP------------WPSVSNL--------AK
         ..|. ..|||..||| ||.|.|..||..|             |  .|...|..|||..  ..            | ..|.         .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFIDRLLTVDPGARMTALQALRHPWV
|.| ..|.|||  |||. |.|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PSKH1.AA RAD53 98-355 35 9.79999999999e-112 334.18 In-house 1-305 (305) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-305/305
Sequence Identity: 35% (110 aa)

YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKY--------REGREVCESELRVLRRVRHANIIQLVEVFET-QERVYMVMELATGGELFDRIIAKG
|..   .|.| |. | ..  . |.| .||| |..|         .  ..  ..|...|... | .||.. ..|.| |. .|||.||.||||||..|.. .
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

S----FTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDS---------------KIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVL
     |.| .. . .   .|.|.||| .||.|||||||| |. |.. .                .| ||||||...   |.. .||| |||| | ||||.
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFV--GEGSFMKTMCGTPQYVAPEVI

VRK---------------PYTNSVDMWALGVIAYILLSGTMPFEDD-----NRTRLYRQILR-GKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQ
. |                || .||.| .|.| ||.|.|. || ||       . |. ||.. |||... . | ..|. |||.|...|.||| .| |. .
TSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDE

ALRHPWV
||.||| 
ALNHPWM
Kinase PSKH1.AA S_TKc 98-355 35 4.6e-103 349.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATG--GELFDRIIAKGS------
|.|  .||.|.|..| .. |. | . .|||.|        |  ..|...|.. .| ||..| .||.. ...|||||.. |  |.|||.|  .|.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTN-SVDMWALGVIAY
|.| .| .... ..... |.| .|| ||||||||.|  .      | |.|||||           .| ||||.|.|||||   .|.  ..|.|..|.| |
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALR-------HPWV
..|.|  ||.  .  .....|.              |  |||||...|..||  |.|| .||.       |||.
EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PSKH1.AA CAMKL 98-355 34 3.4e-98 313.98 In-house 1-297 (297) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-297/297
Sequence Identity: 34% (106 aa)

YDIKALIGRGSFSRVVRVEH-RATRQPYAIKMIETKYREGREVCES---------------ELRVLRRVR---HANIIQLVEVFETQER------VYMVM
|.|   .|.|||. |   .| | |.. .|||.|. |    ......               | . .....   | |||.| ||.||.|       .|.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELATGGE--LFDRIIAK----GSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASA-RK--KGDDCLMKTTCGTPEY
|.. |||  |||.|...    |...|..| |  . ....| |.| .|| |||.||||.|  . |   .| |.|||..   |.  .|.. ..|| ||.|.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

IAPEVLVR--KPYT-NSVDMWALGVIAYILLSGTMPFEDD--------NRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRH
 |||.. .  |||    ||.|..||| | .. |..||.||        |  .||..| .| | .   .|..||  ..|.| ..|.|.|  |.|. | ..|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

PWV
||.
PWM
Kinase PSKH1.AA Pkinase 98-355 33 2.4e-93 321.22 Pfam 1-293 (293) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-293/293
Sequence Identity: 33% (100 aa)

YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCES-----ELRVLRRVRHANIIQLVEVFETQERVYMVMELATGG----ELFDRII--A
| |.  ||.|||..| .  |. |.. .|.| |. . .|  .....     |.....|..| ||..| ..||.  ..|||||.. ||    .|||.|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KGSF--TERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYY-HPGTDSKIIITDFGLAS-ARKKGDDCLMKTTCGTPEYIAPEVLV-RKPYTNSVDMW
.|.|  .|... ...  .| |. |.|. || ||||||||.|.  .. .|... |.|||||  ..    .  |.| ||||.|.||||.  ...|. .||||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

ALGVIAYILLSGTMPFEDD------NRTRLYRQILRGKYSYSGEPWPSVS-----------------NLAKDFIDRLLTVDPGARMTALQALRHPWV
..|.| |..|.|  || ..      .   ....|........ . | |.|                   .||||...|..||  | || |.| |||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PSKH1.AA CAMK-Unique 98-355 25 4e-92 304.42 In-house 1-363 (363) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-363/363
Sequence Identity: 25% (93 aa)

YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYRE-GREVC-------------------ESELRVLRRVRHANIIQLVEV----FETQE-------
|.   .|| |.|. | ..  |.|.  .|.||.. .. .  . .                    . |......| | |||.|...    |.. .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RVYMVMELATGGELFDRIIA--------------------KGSFTE--RDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGT-----
        . |.|||...||.||| |..                    .|.|.|  .|.... | .|  | |.| ..| |||||.||.... ..      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------DSKIIITDFGLASARKKGDDC-LMKTTCGTPEYIAP--------------EVLVRKPYTNSV----DMWALGVIAYILLSGTMPFEDDNRT-
        ...| ..||||.        | .|.|.||||.|.||              ||. . .|   .    | |.||||.|..|.| .||. ..   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------RLYRQILRGKY-SYSGEPWPS---VSNLAKDFIDRLLTVDPGARMTALQALRHPWV
       .... |. |.| ... . | .   .|. ||||.....||||  | .| ..| |.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase PSKH1.AA DCAMKL 98-355 38 1.6e-91 285.0 In-house 1-279 (279) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-279/279
Sequence Identity: 38% (109 aa)

YDIKALIGRGSFSRVVRVEHRATR-QPYAIKM-----------------IETKYREGRE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGG
|.| ..|| | |. |  . || |. . || |.                 |. .   | |   ..|........| .||||.|...|..  |.|||...||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYH--PGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTN
 ||| |.  . |||||| . .  .    .||| ..| |||.|||||| .    |    .   |||||   .. |  .. | |||| |.|||.|  . |  
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSLKLCDFGLACHVNG-DFGPLYTVCGTPTYVAPEILMETGYGC

SVDMWALGVIAYILLSGTMPF--EDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV
 ||.||.||| |||| |  ||  .|.. ..|  ||. ||...    |  .|  ||| | ..| ||| .| || | . ||||
KVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase PSKH1.AA CDPK 98-355 41 1.1e-89 275.26 In-house 1-271 (271) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-271/271
Sequence Identity: 41% (112 aa)

YDIKALIGRGSFSRVVRVEHR-ATRQPY-AIKMIETKYREGREV---C-ESELRVLRRVRHANIIQLVEVFETQERVYMVME--LATGGELFDRIIAKGS
|.||  .|.|.|. | .| |. .| |   |.|.|. | |   .    .   |. .|.   | |||.. |... .  .| |||  . |||||||.||.||.
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIP-KSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH

FTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDS----KIIITDFGLASARKKG---DDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWA
|||..|  . . .|  | | |  .|.||||||||.|.    .||     | . |.|..   ..    .|  |.. |||| ||||||| .| |  ..| | 
FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWS

LGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV
.||| ||||.|. ||  .|.   . ..  ||||. |. | ..|. ||| | ..|..||  ||.| ||| |||.
CGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase PSKH1.AA RSK 100-355 31 2.8e-88 299.61 In-house 1-278 (278) Show / Hide 
Range on Protein: 100-355
Range on HMM: 1-278/278
Sequence Identity: 31% (89 aa)

IKAL--IGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREV----CESELRVLRRVR-HANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGS---
.| |  .| |... . ...|..|.| || | .. . .  |..    .  | ..| |.. | .|..| ..|.|.. .|..||.  |||||...  ...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTD-SKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLV---RKP-YTNSVDMWALG
|.|..|  ..  .   |..|| .|| |||||||| || .   .   | .||||..  ..  .  ...| |.| ||.|||.|    ..  .. ..| | ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VIAYILLSGTMPFED---DNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMT-----ALQALRHPWV
|. | .|.|  ||     .||  . ..|..||.| ... |...|. |||.| ..|..||  | .     | . ..||| 
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PSKH1.AA RSK 98-355 35 3.2e-88 299.4 In-house 1-271 (271) Show / Hide 
Range on Protein: 98-355
Range on HMM: 1-271/271
Sequence Identity: 35% (97 aa)

YDIKALIGRGSFS---RVVRVEHRATRQPYAIKMIETKYREGR--EVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTE
|...  ||.||||    . ...|..|.| ||.| |. . |  .     | |  .|| . |..|..| .||.... |||.|... ||.||||. ....|.|
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSE

RDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHP-GTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILL
|..  ..  ..  . ||| .|| |||||||| ||    |. . | |.|||.|    .... . .| |.| .|.||||| |. .. ..| | .||. |. |
REVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQ-LRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

SGTMPFEDDNRTRLYRQILR---GKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTA-----LQALRHPWV
.|. ||   .| ..  .|.|   |..| ..  | ..|  ||| . ..|..||  | .|      |...|||.
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase PSKH1.AA TyrKc 98-358 20 9e-14 0.01 SMART 1-280 (280) Show / Hide 
Range on Protein: 98-358
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRV--RHANIIQLVEVFETQ-------ERVYMVMELATGGELFDRIIAKG
   .  .|.| | .|.. . .   .. |.||.       ||   .|.|.....  .| ||..|. |  .|       | ...|||.. .| | |.. ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

S-FTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKG-------DDCLMKTTCGTPE-----YIAPEVLVRKPYT
  .. .|       . .| .|||  .. ||||   | |. ...    . |.||||. . . .       |   .|.. |.         |||..  . .|
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

NSVDMWALGVIAY-ILLSGTMPFED-----DNRTRLYRQILRGKYSYSGEP-WP-----SVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSM
   | |. ||  . |.  | .| ..      . ....... .|..    .   |       . . .  . .    ||  | |  .      .  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI-----HECF
Kinase PSKH1.AA Pkinase_Tyr 98-219 23 3.9e-11 38.34 Pfam 1-137 (270) Show / Hide 
Range on Protein: 98-219
Range on HMM: 1-137/270
Sequence Identity: 23% (33 aa)

YDIKALIGRGSFSRVVRVEHR----ATRQPYAIKMIETKYREG----REVCESELRVLRRV-RHANIIQLVEVFE-TQER--VYMVMELATGGELFDRII
  .   .|.|.| .|.. . .     |..| |.||.  .. .     ..  . |.....   .| ||..|. |    .|   .|.|||.. .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

A----KGSFTERDATRVLQMVLDGVRYLHALGITHRDL
.    |...|  |     . . .|  ||.. .. ||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL