Gene PRKX (Human)

PRKX

Species: Human
Alias: PRKX, PKX1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: Xp22.33,

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
PRKX.NA RNA Sugen Kinome 6056 None Fasta, JSON
PRKX.AA Protein Sugen Kinome 358 None Fasta, JSON
PRKX.kin_dom Protein Kinase Domain Sugen Kinome 255 None Fasta, JSON

Protein domain

Protein domains of PRKX.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PRKX.AA PKA 49-303 61 1.6e-202 679.13 In-house 1-263 (263) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-263/263
Sequence Identity: 61% (163 aa)

FDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIR-LFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSST
|....|.|||.||||.|...|. ....|.|........||||..||||||..|....|||... . ||..|.|.|||.||||||||.|||||..||||. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

TGLFYSA-EIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSK-GHGRAVDWWALGILIFEMLSGFPPFF
...|| | .|..|.|||||..|.||||||||||.|..||||.||||||||..||||||||||||||||.|||| |||..||||||||||.|||.|.|||.
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

DD--NPFGIYQKILAGKIDFPRHLDFHV---KDLIKKLLVVDRTRRLGNMKNGANDVKHHRWF
|.  .|..||.||..|||.||||.| ..   ||||||||.||.|.|.||||||.||.|.|.||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase PRKX.AA AGC 49-303 32 5.4e-180 470.24 In-house 1-395 (395) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-395/395
Sequence Identity: 32% (130 aa)

FDTLATVGTGTFGRVHLVKEK------TAKHFFALKVMSIPD-VIRLK--QEQHVHNE------------KSVLKEVS----------HPFLIR-LFWTW
|. | ..|.|.||.|.||..|      . ....|.||..  . ....|  ...|...|            . .|....          |||... |. ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

HDERF--LYMLMEYVP---------GG-ELFSYLR---NRGRFSSTTGLFYSAE-------IICAIEYLHS-KEIVYRD-LKPENILLDRDGHIKLTDFG
.|..   ||..|||.|         || |||..|.   ..|||.  .  || ||       |..|.||||| . |..|| |||||||||.||||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKKLV-----------------------------------------------------DRTWTLCG--TPEYLAPEVIQSKGHGRAVDWWA--LGILIF
..|...                                                     |||||.||  ||||.|||..    .|.|.|||.  ||.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLSGFPPFFDDN----------PFGIYQKILAG------KIDFP----------RHLDFHVKDLIKKLLVVDRTRRLGNMKN-----GANDVKHHRWF
|||.| |||..||          |. ..|||. |      |. ||          |...   ||||||||..|...|||...|     ||...| | ||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PRKX.AA SGK 49-303 40 1.1e-122 380.85 In-house 1-283 (283) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-283/283
Sequence Identity: 40% (115 aa)

FDTLATVGTGTFGRVHLVKEKTA------------------KHFFALKVMSIPDVI-------RLKQEQHVHNEK-SVLKEVSHPFLIRLFWTWHDERFL
|| | ..| | ||.| .|| |                    . |.|.|| .   .|       . |.. |.  |.  .|| ..|||.. |      .  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAK---KLVDRTWTLCGTPEYLAPEVIQSK
|. |.|| |||.|..|. ...|.     || |||.||.|||||. |.|||||||||||| .||..||||| .|   |  | | | |||||||||||.. .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWF
.|.|.|||| ||.. .||..| |||.. |    |..|. ... .|.      .|||. ||  |.. |||  |... ..| | .|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLG-TKRDFMEIKNHPFF
Kinase PRKX.AA Akt 49-303 45 4.5e-119 382.29 In-house 1-264 (264) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-264/264
Sequence Identity: 45% (119 aa)

FDTLATVGTGTFGRVHLVKEKTAKHFF-ALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSST
|| |   | |.||.| |||.|  . .. |.|| .    |  .| .|.  |. .|. . |||.. |     ..  ||. |.|..|||||..|. ..|||  
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

TGLFYSAEIICAIEYLHSKEIVYRD-LKPENILLDRDGHIKLTDFGFAKKL-VDR---TWTLCGTPEYLAPEVIQSKGHGRAVDWWA-LGILIFEMLSGF
.  || ||||.|||.|||| |.||| |||||||.|.||||.||||| .|.  . .   | |.||||||||||... .||..|||||. ||....||. |.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFFDDNPFGIYQKILAGKIDFP--RHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWF
|||....    ..||. ... ||  . ..   ||||..||  |...|||. .|.|...| | ||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase PRKX.AA AktR 49-303 42 4.3e-115 388.65 In-house 1-268 (268) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-268/268
Sequence Identity: 42% (113 aa)

FDTLATVGTGTFGRVHLVKEK-TAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLK-EVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSS
|. ..  | |.||.| ||..| . . ..|.|. .  . |...|..|. .|. ... ...|||...|. .. ... |. .|||.||||||..|.....|| 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

TTGLFYSAEIICAIEYLHSK-EIVYRDLKPENILLDRDGHIKLTDFGFAK---KLVD--RTWTLCGTPEYLAPEVIQS-KGHGRAVDWWALGILIFEMLS
 . .||.|.|. |.||||..  |.|||||||||||| |||.|.|||| .|   . ..  .. ..||||||.|||.|.  |||...|||||.||.|.||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GFPPFFDDNPFGIYQKILAGK-IDFPRHLDF--HVKDLIK-KLLVVDRTRRLGNMKNGANDVKHHRWF
| |||...|   ..|||.    . || . .|  . ||||. |||  . . |||  .||. ..| | ||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase PRKX.AA PKG 49-303 48 1.7e-110 373.39 In-house 1-260 (260) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-260/260
Sequence Identity: 48% (126 aa)

FDTLATVGTGTFGRVHLVKEKTAK-HFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSST
.. .|| | | |||| ||. .  |   ||||.|    ..  .|..|. .|| .. | . .| .||. |. |....|||||   |||| . || ||.|   
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

TGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLV--DRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFF
|  || | .. | .|||.| |.||||||||..||..| .|| |||||||.    .||| |||||| |||.|  ||| |.||.||||||..| | | ||| 
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

DDNPFGIYQKILAG--KIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWF
  .|  .|. || |  ...|||.     ...||||     | |||. ||| ||.|.|.||
GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF
Kinase PRKX.AA S_TKc 49-303 36 1.2e-100 341.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPG--GELFSYLRNRGR---
.. | ..| |.||.|.....|  .. .|.|...          .|. .| ..||.  ||....|. ...|  .||| |||..|  |.||.|...|||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGR-AVDWWALGILIFEMLS
   |.  .  || ..|.||.||.||. |..|||||||||||.  |||..|||.|..|     |.||||.|.||||.   |.|. ..|||..|....|||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGA--NDVKHHRWF
| |||   ... ...||.          .  .||.|.|.|..| ..|..  .  .   |.| | ||
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PRKX.AA Ciliate-E2b 49-303 35 1.8e-99 302.84 In-house 1-272 (272) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-272/272
Sequence Identity: 35% (98 aa)

FDTLATVGTGTFGRVHLVKE-KTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRG--RFS
..     | | || | ||.. |. | ..|.|. |.  .|    | |  .||.||. . |||..... .  |....|..||.. |.|||...|. |   .|
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

STTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVD------RTWTLCGTPEYLAPEVIQ-----SKGHGRAVDWWALGILI
    .|| |.|. ..||||...|.|||.|||||..| .|..|| |.| || . .      || |..|||.|.|||.||      || . .|| |..||  
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

FEMLSGFPPFFDD--NPFGIYQKILAG--KIDFPRHLDFHVK--DLIKKLLVVDRTRRLGNMKNGANDVKHHRWF
.|...| .|.  |  .|  |||.|. .  .|.|| ..   ..  .|. ..|      |||      .  | | ||
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGS---YSWLKSHPWF
Kinase PRKX.AA RSK 52-303 39 5.1e-96 325.3 In-house 1-278 (278) Show / Hide 
Range on Protein: 52-303
Range on HMM: 1-278/278
Sequence Identity: 39% (109 aa)

LATVGTGTFGRVHLVKEK---TAKHFFALKVMSIPDVIRLKQ-EQHVHNEKSVLKEVS-HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGR---
|   |.| .| | |....    ... .| || .   ... .    |.  | ..|...  |||...|. . ..|  ||. |||..|||||  |.....   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDR---DGHIKLTDFGFAKK-LVD---RTWTLCGTPEYLAPEVIQ----SKGHGRAVDWWALGI
|| ..  || |||..|.|.||.. |..|||||||||.|    .||||||||||.|.   |   .| | |.| ||.|||..      .||..|.||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIFEMLSGFPPFFD---DNPFGIYQKILAGK--IDFP--RHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWF
|..|||.|.|||     .|.  | ..|. ||   ..|    |    ||||.|.| .|  .|||  ...|...| | ||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PRKX.AA Pkinase 49-303 31 5.5e-92 316.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

FDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVH-NEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGG----ELFSYLR--NR
. .. ..| |.||.| . ..|   . .|.|... ..    |...|.. .| ...|...||. .||. ...|.. .|| |||..||    .||.|..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRF--SSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHI----KLTDFGFAK---KLVDRTWTLCGTPEYLAPEVIQ-SKGHGRAVDWWALG
|.|  |  .  ||  .|....||.||. |..|||||||||.|..|||    |..|||.||      ....|.||||.|.|||||. ....|..||.|..|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

ILIFEMLSGFPPFFDD------NPFGIYQKILAGKIDFPRHLD---------------------FHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWF
....|||.| ||| ..      ..  ....|. ....|..  .                        ||.||..| .| ..|..     | ....| ||
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase PRKX.AA p70 49-303 36 7.9e-90 304.73 In-house 1-299 (299) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-299/299
Sequence Identity: 36% (110 aa)

FDTLATVGTGTFGRVHLVKEKT---AKHFFALKVMSIPDVIR-LKQEQHVH-------------------------NEKSVLKEVSHPFLIRLFWTWHDE
|  |  .| | .| | .|.  |   .   .| ||.    ..|  |  .|                            | ..| || |||.. |.   ...
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

RFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDR-------------TWTLCG
  || . || .|||||  |   | .  .|  || .|||||.|.||.. |.||||||||..|.  ||..|||||  |. .               |.|.||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGK--IDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWF
|.|| |||..  .||..|||||.||.|.. || | |||  .|.  .  ||| ||  .  |  |    .|||||||  . | |.|   . | |.. | .|
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase PRKX.AA Ciliate-E2 49-303 26 1.8e-88 300.2 In-house 1-365 (365) Show / Hide 
Range on Protein: 49-303
Range on HMM: 1-365/365
Sequence Identity: 26% (102 aa)

FDTLATVGTGTFGRVHLVKE-----------------------KTAKHFFALKVMSIPDVIRLKQEQHVH----------NEKSVLKEVSHPFLIRLFWT
.. .   |.|.|| | ..|                        |... ..|.|.|.  ... .|||.|.           |||..|....||..|.....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WH--DERFLYMLMEYVPGGELFSYLRNR-----------GRFSSTTGL---------------FYSAEIICAIEYLHSKE-IVYRDLKPENILLDRDGHI
.   |.  .|. |||. ||.||.|..|.           ..|.    .               || |.||.|.||||||  |..||.||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGFAKKLV----------------------------------DRTWTLCGTPEYLAPEVIQSKG---------HGRAVDWWALGILIFEMLSGFPP
|..|||..||.                                   . ..|.||||.|.|||....|.         .. ..|.|.||....|||.| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FFDDNPFGIYQKILAGKIDFPRHL-------------DF-----HVKDLIKK----LLVVDRTRRLGNMKNGANDVKHHRWF
|        .|.|. .|||||                ..      .||||||    .|..|   |..    |..... | ||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF
Kinase PRKX.AA S_TK_X 304-358 20 8.7e-17 63.02 SMART 1-79 (79) Show / Hide 
Range on Protein: 304-358
Range on HMM: 1-79/79
Sequence Identity: 20% (16 aa)

RSVDWEAVPQ--RKLKPPIVPKIA----GDGDTSNFE-TYPENDWDTAAPVPQ------------------KDLEIFKNF
|..||... .  ....||..|||     ...|||||.  ..|.... . |...                  . .. ...|
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase PRKX.AA TyrKc 49-297 20 3.8e-14 6.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 49-297
Range on HMM: 1-280/280
Sequence Identity: 20% (58 aa)

FDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEV--SHPFLIRLFWTWHDE-------RFLYMLMEYVPGGELFSYLR
   . . | | ||.|.. . |      | |..          ..  ..| ......  .|| ..||.    ..         |...|||.|.| | .|||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NRGR-FSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDR-------TWTLC----GTPE-----YLAPEVIQSKGHG
.... ..  . | ..  | |  |||||| .. |||   |.|.......| .||| .... |                 |.        .|||.|. .   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

RAVDWWALGILIFEMLS-GFPPFFD-----DNPFGIYQKILAG-KIDFPRH--------LDFHVKDLIKKLLVVDRTRRLGNMKNGANDV
 . | |. |....|... | .|  .      ... ..... .|   . | .            . ...|.    |   |  ....   . 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-TFSEIHECF
Kinase PRKX.AA Pkinase_Tyr 122-244 28 1e-10 36.94 Pfam 82-216 (270) Show / Hide 
Range on Protein: 122-244
Range on HMM: 82-216/270
Sequence Identity: 28% (39 aa)

LYMLMEYVPGGELFSYLRN----RGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL-------VDRTWTLCGTPEY
.|. |||.|.| | .|||.    .....  . | ....| .. |||.|| .. |||   |.|.......| .||| |. .       . |. .       
IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKW

LAPEVIQSKGHGRAVDWWALGILIFEMLS-GFPP-F
.|||.|. .    . | |. |.|..|... |  | .
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTY