Gene NEK7 (Human)

NEK7

Species: Human
Alias: NEK7
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 1q31,

Classification

Group: Other
Family: NEK
Subfamily: NEK6

Sequence

Name Sequence Type Origin Length Description Download
NEK7.NA RNA Sugen Kinome 4136 None Fasta, JSON
NEK7.AA Protein Sugen Kinome 302 None Fasta, JSON
NEK7.kin_dom Protein Kinase Domain Sugen Kinome 252 None Fasta, JSON

Protein domain

Protein domains of NEK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NEK7.AA NEK6 34-285 91 1.3e-217 723.27 In-house 1-252 (252) Show / Hide 
Range on Protein: 34-285
Range on HMM: 1-252/252
Sequence Identity: 91% (230 aa)

FRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLI
|.||||||.|||||||||.||.|...|||||||||..||||||.||||||||||||||||||||||||||.||||||||||||||.||||||||||||||
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDMSRMIKHFKKQKRLI

PERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ
||||.||||||||||||||||.||||||||||||||||.|.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ

SPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDV
||||||||||||||||||||||||||.|||||.|||||.|||.||||.|||.
SPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQLVCMCIHPDPEWRPDI
Kinase NEK7.AA NEK 34-286 41 1.6e-145 489.76 In-house 1-278 (286) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-278/286
Sequence Identity: 41% (115 aa)

FRIEKKIGRGQFSEVYRAACLLDGVP-----VALKKVQIFDLMDAKARADCI-KEIDLLKQLNHPNVIKYYASFIEDN--ELNIVLELAD-AGDLSRM--
..| ||||.|.|..||.. .  ||       ...||.. .. |. | . ... .|. .||||.|||..||| ||||..   |.|| | ..  |||...  
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-IKHFKKQKRLIPERTVWKYFVQLCSALEHMHSR-----RVMHRDIKPANVFITATGV----VKLGDLGLGRFFSSKTTAAHS-LVGTPYYMSPERIHEN
 ||. |... ...|...|..|.|.|.|| .||.|     ...||||||.|.|.|. .     ||.||.|. . ....|..|.. .|||||||||| ... 
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

GYNFKSDIWSLGCLLYEMAALQS--PFYG-DKMNLYSLCKKIEQC-DYPPLPSDH-YSEELRQLVNMCINPDPEKRPDVT
.||.|||||||||.||||..|..  ||.. | ||..||..|| .. .|||.|| . ||..|..|.......|||.||...
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWD-MNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCN
Kinase NEK7.AA NEK8 71-285 43 5.7e-95 271.58 In-house 39-269 (278) Show / Hide 
Range on Protein: 71-285
Range on HMM: 39-269/278
Sequence Identity: 43% (102 aa)

MDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPER----------------TVWKYFVQLCSALEHMHS
|. | | .   ||..|. |.|||.| || .|.||| | |..| || | | .|| |  . | . .||                ..  ||.| |||. |||.
MSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQH-QQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQ

RRVMHRDIKPANVFITAT-GVVKLGDLGLGRFFSSKTTAAHS--LVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIE
  . |||.|..|.| |   .|||.|| |.    ..|. .. .  .||||||||||      ||.|||.|.||| ||||. |   | ..  ||  |. || 
HNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEAS--NLPALVWKIM

QC-DYPPLPSDHYSEELRQLVNMCINPDPEKRPDV
||  | |. ||||| |.|.||  |   |||.||..
QCRAYEPI-SDHYSNEMRMLVHNCLQQDPEQRPSA
Kinase NEK7.AA S_TKc 34-299 31 5.6e-94 319.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-299
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

FRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADA--GDLSRMIKHFKKQK-
..| .|||.| |..||..    .|  ||.|..            . ..||..||. .|||..|.| .| . ..| .|.|..|   ||| ..||. .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-RLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNF-KSDIWSLGCLLYE
 . .|| ....|. |.|.|||..||....|||.||.|....   ..|..| || |..       ....|||.||.|| .   ||.. |.|.||.||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYD--VAKRMHACT
|.. . ||.    ... . |||             |.|...... | . |||||| .  .    .. ..|   
MLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK7.AA Pkinase 34-283 28 1.6e-78 271.93 Pfam 1-282 (293) Show / Hide 
Range on Protein: 34-283
Range on HMM: 1-282/293
Sequence Identity: 28% (81 aa)

FRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCI-KEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAG----DLSRMIKHFKK
..|..|||.| |..||..    .|  ||.|..   .  . | ...    || ..| |||||....| .| ..... .|.|... |    ||...|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

QKRLI--PERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVV----KLGDLGLGRFF-SSKTTAAHSLVGTPYYMSPERIH-ENGYNFKSDIW
... .  .|... .|. |....||..||....|||.||.|..|  .|..    |..| || ..|   . . .....|||.||.|| |   ..|  |.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGCLLYEMAALQSPFYGD----KMNLYSLCKKIEQCDYPPLPSDHYS-------------------EELRQLVNMCINPDPEKRP
|.||.||||.  . ||.|.    ... . . ..| .....   .  .|                   ||...... |...||.|||
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP
Kinase NEK7.AA STE 34-286 25 9.3e-76 258.0 In-house 1-349 (359) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-349/359
Sequence Identity: 25% (91 aa)

FRIEKKIGRGQFSEVYRAACLL---------------DGVPVALKKVQIFD------------LMDA--KARADCIKEIDLLKQLN--HPNVIKYYASFI
... .|||.| | .||.|..                  |. .| |.. . .            |..   . . . .|||...|..|  |||..||| ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------NELNIVLELADAGDLSRMIK-HFKKQKRL---------IPERTVWKYFVQLCSA-LEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGR
 .       .||.|..|. |.| |. .||  ....|.|         .||  . .. .|.. . |.. || ...||||||||...     ||| | |.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FFSSK--------------TTA--AHSLVGTPYYMSPERIHE------NGYNFKSDIWSLGCLLYEMAALQSPFYG-DKM-NLYSLC--KKIEQ------
 ....              |..    ..|||| .|.||.|        .||..|.|||||||.. |||  . |.     | ...     ....|      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---CDYPPLPSD------------------HYSEELRQLVNMCINPDPEKRPDVT
    . ||||..                  ..|.|... .| | . ||.|||...
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTAS
Kinase NEK7.AA NEK1 34-286 37 2.7e-75 256.48 In-house 1-268 (276) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-268/276
Sequence Identity: 37% (102 aa)

FRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNE--LNIVLELADAGDLSRMIKHFKKQKR
. . |.|| | |  .. .    || . ..|  ..   |  | | .  .|  .|. . |||..||. ||.|     | || | .|.||| . |.  | .  
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMK-MQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGK

LIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFIT--ATG---------------VVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYN
|..| .   .|.|.| || |.|.|...|||||. |.| |    |               .||||| |  |  .. .  |   .||||| ||| .   .||
LFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYN

FKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVT
 ||||||||| |||  .|  || . ..    |  || |  |||.|. |||.||. ||    . .|. || |.
NKSDIWSLGCVLYELCTLKHPFEANNWK--NLVLKICQGTYPPIPP-HYSYELQSLVSQMFKRNPRHRPSVN
Kinase NEK7.AA CAMK 39-283 20 5.5e-71 227.75 In-house 1-414 (425) Show / Hide 
Range on Protein: 39-283
Range on HMM: 1-414/425
Sequence Identity: 20% (87 aa)

KIGRGQFSEVYRAACLLDG------------VPVALKKVQIFDLMD-------------------------AKARADCIKEIDLLKQ-------LNHPNV
..|||.|..|...   ...            . || | .    | |                         .| |.   .||...|.       |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKYYASFIE-------------------DNELNIVL---ELADAG----D-LSRMIKH-----------FKKQKRLIPERTVWKYFVQLCSALEHMHSRR
|| |  .                     |... .|.   |... |    | ... ..|           .  ... ..|| . .|| |.|||....||. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

VMHRDIKPANVFITAT-----------------GVVKLGDLGLGRFFSSK-----------------------TTAAHSLVGTPYYMS-PERIH------
..|||.|| |. ..                   . .|. | |. ..| ..                       .   .  .|||.||. || .       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ENGYNFKSDIWSLGCLLYEMAALQSPFYGD-----------KMNLYSLCKKIEQCDY--PPLP------------SDHYSEE--------LR
        . .|..|.|.||.|..|| |    .|||||           .||.| |..|| ...|  || .             |. |.|         .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

QLVNMCINPDPEKRP
.|.. . ..|||||.
DLIRKMLQVDPEKRM
Kinase NEK7.AA ULK 34-282 25 1.5e-63 217.41 In-house 1-312 (324) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-312/324
Sequence Identity: 25% (80 aa)

FRIEKKIGRGQFS-EVYRAACLLD---GVPVALKKVQIFDLMDAKARAD------CIK-EIDLLKQLN---HPN--VIKYYASFIED--NELNIVLELAD
. . ...| |.|   ||.. .  .   .. || |..... . . | ...       .| || ..|.|.   |||  ..|.|  | ..  | . |..|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGDLSRMIKHFKK-----QKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITAT------------GVVKLGDLGLGRFFS---SKTTAAHS
 |||.  ||  ||      |. ..|  . ..| |.|... ..|.. ..||||||.|  |.              ||.|..| |.....       .  ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

LV------GTPYYMSPERIHENG----YN-FKSDIWSLGCLLYEMAALQSPFYGDKMNLY----SLCKK-------IEQ--CDYPPL-PSDHYSEELRQL
.|      |||.||.|. ....|    |. .|.|||||||..|||   . ||.......|    .| ..       |..   ..|.  .... |.|...|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VNMCINPDPEKR
   ..  |...|
IRRMLQYDEKDR
Kinase NEK7.AA NEK4 34-285 37 3.6e-63 216.18 In-house 1-248 (257) Show / Hide 
Range on Protein: 34-285
Range on HMM: 1-248/257
Sequence Identity: 37% (96 aa)

FRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLM--DAKARADCIKEIDLLKQLNHPNVIKYYASF-IEDN-ELNIVLELADAGDLSRMIKHFKKQ
. . | .|.| . ||.      |.    .||..   |   . . | .  .|. || || |||...|  |. ||..  | ||.   . ||| |  |  | |
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMF---LKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQ

KRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEM
  ...|. |   |||   ||  || ....||| |  |.|.| . ..|.||.|. |    .   |  ..|||||||||      |..||||||||| .|||
--FLEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEM

AALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDV
. |   |    ||  ||  .| |   ||.| . ||..| .||   ..  |.||| .
ITLKHAFDAKDMN--SLIYQIIQGQPPPMPPN-YSQDLQNLVYQMLEKQPTKRPSI
Kinase NEK7.AA ULK 34-282 24 6.7e-63 215.29 In-house 1-317 (329) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-317/329
Sequence Identity: 24% (78 aa)

FRIEKKIGRGQFSEVYRAACLLD----GVPVALKKVQIFDLMDAKARAD-------CIKEIDLLKQLN--------HPNVIKYYASFIED--NELNIVLE
. . ...| |.|  ||.. .  .    .. || |..... .   .  ..        ..||...|.|.        |||..|.|  | ..  | . |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LADAGDLSRMIKHFKK------QKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITAT------------GVVKLGDLGLGRFFSSK---TT
. . |||.  ||  ||       |. ..|  . ..| |..... ..|.....||||||.|. |.              ||.|..| |.......      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

AAHSLV------GTPYYMSPERIHENG----YN-FKSDIWSLGCLLYEMAALQSPFYGD--KMNLYSLCKKIEQ------------CDYPPL-PSDHYSE
 ... |      |||.||.|. ....|    |. .|.|||||||..|||   . |||.   . .|. . | |..             ..|.  .... |.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ELRQLVNMCINPDPEKR
|...|   ..  |...|
ECKDLIRRMLQYDEKDR
Kinase NEK7.AA Ciliate-E2 34-284 23 8.8e-63 214.33 In-house 1-354 (365) Show / Hide 
Range on Protein: 34-284
Range on HMM: 1-354/365
Sequence Identity: 23% (85 aa)

FRIEKKIGRGQFSEVYRAACLLDG--------------------VPVALKKVQIFDLMDAKARAD---CIKEID----------LLKQLNHPNVIKYYAS
. . ||||.|.|. ||..   ...                    | . .. . |.   . ..       ..||.          .|.||||||.||.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FI--EDNELNIVLELADAGDLSRMIKHF-KKQKRLIP------ERTVWKYFVQLCS---------------ALEHMHSRR-VMHRDIKPANVFITATGVV
|.   || . .|.|... |||   ||.. ||..  |.      |. . ... |...               |||..||.  ..|||||| |...     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLGDLGLGRFFSSKTT-------------------------------AAHSLVGTPYYMSPERIH---------ENGYNFKSDIWSLGCLLYEMAALQSP
|. |.|| .... .                                  .....|||.||.|| .          ..||..|.||||||..||||   . |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYGDKMNLYSLCKKIE-QCDYPPL--------------PSDHYSEELRQLVNM----CINPDPEKRPD
|         . .... ..|.|.                 .. |.|  .| .     ... |||||..
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT
Kinase NEK7.AA TyrKc 34-292 22 5.3e-34 120.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-292
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQL--NHPNVIKYYASFIED-------NELNIVLELADAGDLSRMIK
 . .||.|.|.| |||..      ..|| |...         |.| ..|. ....|  .|||... |.  ...         | ||.|... |||   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

HFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSK--------TTAAHSLVGTP-----YYMSPERIHEN
  ...   .. ..  .. .| ..  |. ||... |||.   |. ... ..|| .| || |.  ..        .  . .  |.        |.|| | ..
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYNFKSDIWSLGCLLYEMAALQSPFYGD----KMNLYSLCKKIEQCDYPPLPSD-------HYSEELRQLVNMCINPDPEKRPDVTYVYDVA
 ...|||.|| | ...|.  .  . | .    .|. . . ....| ...| | .       . ..|. |.  .| . |||.||  . ...  
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase NEK7.AA Pkinase_Tyr 34-283 26 5.1e-30 102.3 Pfam 1-261 (270) Show / Hide 
Range on Protein: 34-283
Range on HMM: 1-261/270
Sequence Identity: 26% (70 aa)

FRIEKKIGRGQFSEVYRAACL----LDGVPVALKKVQIFDLMDAKA--RADCIKEIDLLKQL-NHPNVIKYYASFI-EDNE--LNIVLELADAGDLSRMI
 .. ||.|.|.| |||.. .      ...||| |..   .  . ..  |.| ..|. ..||| .|||....|.  . ..    . ||.|..  |||    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF--SSKT-TAAHSLVGTPYYMSPERIHENGYNFKSDIW
.  . .|. ..  .  .. .| ....|. .|..  |||.   |. .| ..||| .| || |     .   .....       |.|| |... .. |||.|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGCLLYEMAAL-QSP-FYGDKMNLYSLCKKI-EQCDYPPLPSDHYSEELRQLVNMCINPDPEKRP
| | |..|.  . ..| ..|  |  . ....| |.  |   . .. ..|. .|  .| ..|||.||
SFGVLMWEIFTYGEQPTYPG--MSNEEVYEYIYED-GYRMPCPENCPDEIYDLMKQCWHYDPEDRP