Gene NEK6 (Human)

NEK6

Species: Human
Alias: NEK6, SID6-1512
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 9q34.1,

Classification

Group: Other
Family: NEK
Subfamily: NEK6

Sequence

Name Sequence Type Origin Length Description Download
NEK6.NA RNA Sugen Kinome 2810 None Fasta, JSON
NEK6.AA Protein Sugen Kinome 347 None Fasta, JSON
NEK6.kin_dom Protein Kinase Domain Sugen Kinome 261 None Fasta, JSON

Protein domain

Protein domains of NEK6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NEK6.AA NEK6 79-330 87 3.7e-215 715.02 In-house 1-252 (252) Show / Hide 
Range on Protein: 79-330
Range on HMM: 1-252/252
Sequence Identity: 87% (221 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLI
||||||||.|||||||.|.||.|.|.||||||||||||||||||||.|||.|||||||||.|||..||||.||||||||||||||.|.|||.||||||||
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDMSRMIKHFKKQKRLI

PERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ
||||.||||||||||.|||||.||||||||||||||||.|.||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||
PERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ

SPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDI
||||||||||.|||.|||||||||||..||||.||.||.|||.|||..||||
SPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQLVCMCIHPDPEWRPDI
Kinase NEK6.AA NEK 79-330 42 2.1e-145 489.38 In-house 1-277 (286) Show / Hide 
Range on Protein: 79-330
Range on HMM: 1-277/286
Sequence Identity: 42% (118 aa)

FQIEKKIGRGQFSEVYKATCLLDRKT-----VALKKVQIFEMMDAKARQDCV-KEIGLLKQLNHPNIIKYLDSFIEDN--ELNIVLELAD-AGDLSQM--
..| ||||.|.|..|||. .  | |      ...||.. ...|. | .|... .|. .||||.||||.|| |||||..   |.|| | ..  |||.|.  
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-IKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR-----RVMHRDIKPANVFITATGV----VKLGDLGLGRFFSSETTAAHS-LVGTPYYMSPERIHEN
 ||  |... ...|...|..|.|.|.|. .||.|     ...||||||.|.|.|. .     ||.||.|. . ....|..|.. .|||||||||| ... 
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

GYNFKSDIWSLGCLLYEMAALQS--PFYG-DKMNLFSLCQKIEQC-DYPPLPGEH-YSEKLRELVSMCICPDPHQRPDI
.||.|||||||||.||||..|..  ||.. | ||. ||. || .. .|||.|  . ||..|..|.|.....||.|||..
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWD-MNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSC
Kinase NEK6.AA S_TKc 79-344 30 2.4e-95 323.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 79-344
Range on HMM: 1-231/231
Sequence Identity: 30% (84 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADA--GDLSQMIKYFKKQK-
..| .|||.| |..|||..   . . ||.|..           ..  .|| .||. .||||.|..|.| . ..| .|.|..|   ||| ..||  .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-RLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNF-KSDIWSLGCLLYE
 . .|| ....|. |.|.|.|..||....|||.||.|....   ..|..| || |..       ....|||.||.|| .   ||.. |.|.||.||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQ--VAKQMHIWM
|.. . ||.    ... . .||             |. ...... | . || .|| .  . |  ..  .| |.
MLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK6.AA NEK8 116-329 43 1.4e-90 258.82 In-house 39-268 (278) Show / Hide 
Range on Protein: 116-329
Range on HMM: 39-268/278
Sequence Identity: 43% (101 aa)

MDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPER----------------TVWKYFVQLCSAVEHMHS
|. | ||.   || .|. |.||||| |.|.|.||| | |..| || | | |||    . | . .||                ..  ||.| |||| |||.
MSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQH-QQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQ

RRVMHRDIKPANVFITAT-GVVKLGDLGLGRFFSSETTAAHS--LVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIE
  . |||.|..|.| |   .|||.|| |.    .... .. .  .||||||||||      ||.|||.|.||| ||||. |   | ..  ||  |. || 
HNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEAS--NLPALVWKIM

QC-DYPPLPGEHYSEKLRELVSMCICPDPHQRPD
||  | |.. .|||  .| ||. |   || |||.
QCRAYEPIS-DHYSNEMRMLVHNCLQQDPEQRPS
Kinase NEK6.AA Pkinase 79-330 28 9.9e-81 279.31 Pfam 1-284 (293) Show / Hide 
Range on Protein: 79-330
Range on HMM: 1-284/293
Sequence Identity: 28% (81 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCV-KEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAG----DLSQMIKYFKK
..|..|||.| |..|||..   ..|.||.|..   .  . | ...    || ..| ||||||....|.| ..... .|.|... |    ||. .|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

QKRLI--PERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVV----KLGDLGLGRFF-SSETTAAHSLVGTPYYMSPERIH-ENGYNFKSDIW
... .  .|... .|. |.....|..||....|||.||.|..|  .|..    |..| || ..|     . .....|||.||.|| |   ..|  |.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGCLLYEMAALQSPFYGD----KMNLFSLCQKIEQCDYPPLPGEHYS-------------------EKLRELVSMCICPDPHQRPDI
|.||.||||.  . ||.|.    ...   . ..| .....    . .|                   | ...... |.|.||..|| .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA
Kinase NEK6.AA NEK1 79-342 36 4.2e-79 269.1 In-house 1-276 (276) Show / Hide 
Range on Protein: 79-342
Range on HMM: 1-276/276
Sequence Identity: 36% (104 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNE--LNIVLELADAGDLSQMIKYFKKQKR
. . |.|| | |  .....   |... ..|  .. .| . | |.. ..|  .|. . ||||.|| .||.|     | || | .|.||| | |.  | .  
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQE-KEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGK

LIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFIT--ATG---------------VVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYN
|..| .   .|.|.| |. |.|.|...|||||. |.| |    |               .||||| |  |  ....  |   .||||| ||| .   .||
LFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYN

FKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMHI
 ||||||||| |||  .|  || . ..    |  || |  |||.|  |||..|..|||     .|  ||    |.|. ..  |
NKSDIWSLGCVLYELCTLKHPFEANNWK--NLVLKICQGTYPPIP-PHYSYELQSLVSQMFKRNPRHRPS---VNQILERPFI
Kinase NEK6.AA STE 79-329 24 6.4e-74 251.9 In-house 1-347 (359) Show / Hide 
Range on Protein: 79-329
Range on HMM: 1-347/359
Sequence Identity: 24% (88 aa)

FQIEKKIGRGQFSEVYKATCLL---------------DRKTVALKKVQIFEM--------------MDAKARQDCVKEIGLLKQLN--HPNIIKYLDSFI
... .|||.| | .|||| .                   . .| |.. . .               .. . .|.  ||| ..|..|  ||||.||.....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------NELNIVLELADAGDLSQMIK-YFKKQKRL---------IPERTVWKYFVQLCSA-VEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGR
 .       .||.|..|. |.| |...|| .....|.|         .||  . .. .|.. .  .. || ...||||||||...     ||| | |.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FFSSE--------------TTA--AHSLVGTPYYMSPERIHE------NGYNFKSDIWSLGCLLYEMAALQSPFYG-DKM-NLFSLC--QKIEQ------
 ....              |..    ..|||| .|.||.|        .||..|.|||||||.. |||  . |.     | ..|     ....|      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---CDYPPLPG------------------EHYSEKLRELVSMCICPDPHQRPD
    . ||||                   ...|..... .. |   ||..||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase NEK6.AA ULK 79-327 26 1.6e-68 234.0 In-house 1-312 (324) Show / Hide 
Range on Protein: 79-327
Range on HMM: 1-312/324
Sequence Identity: 26% (83 aa)

FQIEKKIGRGQFS-EVYKATCLLD---RKTVALKKVQIFEMMDAKAR-------QDCVKEIGLLKQLN---HPN--IIKYLDSFIED--NELNIVLELAD
... ...| |.|   |||...  .    . || |......| . | .       |   .|| ..|.|.   |||  |.|..| | ..  | . |..|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGDLSQMIKYFKK-----QKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITAT------------GVVKLGDLGLGRFFS---SETTAAHS
 |||.| ||  ||      |. ..|  . ..| |.|..  ..|.. ..||||||.|  |.              ||.|..| |.....     | .  ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

LV------GTPYYMSPERIHENG----YN-FKSDIWSLGCLLYEMAALQSPFYGDKMNLF----SLCQK-------IEQ--CDYPPL-PGEHYSEKLREL
.|      |||.||.|. ....|    |. .|.|||||||..|||   . ||........    .| ..       |..   ..|.  .. . |.....|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VSMCICPDPHQR
 . ... |. .|
IRRMLQYDEKDR
Kinase NEK6.AA CAMK 84-330 20 7.8e-68 217.42 In-house 1-416 (425) Show / Hide 
Range on Protein: 84-330
Range on HMM: 1-416/425
Sequence Identity: 20% (84 aa)

KIGRGQFSEVYKATCLLDR------------KTVALKKVQIFEMMD-------------------------AKARQDCVKEIGLLKQ-------LNHPNI
..|||.|..|....  ..             . || | .    . |                         .| |.   .|| ..|.       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKYLDSFIE-------------------DNELNIVL---ELADAG----DLSQMIKYFKKQK-----------RLIPERTVWKYFVQLCSAVEHMHSRRV
|| .. .                     |... .|.   |... |    || ..|.  ..             . ..|| . .|| |.||||...||. .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDIKPANVFITAT-----------------GVVKLGDLGLGRFFSS-----------------------ETTAAHSLVGTPYYMS-PERIH-------
.|||.|| |. ..                   . .|. | |. ..| .                       |.   .  .|||.||. || .        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------ENGYNFKSDIWSLGCLLYEMAALQSPFYGD-----------KMNLFSLCQKIEQCDYPPLPGE----------------------HYSEKLRE
       . .|..|.|.||.|..|| |    .|||||           .||.  |..|| ...|   | .                      . |.  . 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVSMCICPDPHQRPDI
|.. . ..|| .|. |
LIRKMLQVDPEKRMTI
Kinase NEK6.AA ULK 79-327 25 9e-68 231.46 In-house 1-317 (329) Show / Hide 
Range on Protein: 79-327
Range on HMM: 1-317/329
Sequence Identity: 25% (80 aa)

FQIEKKIGRGQFSEVYKATCLLDR----KTVALKKVQIFEMMDAKARQD-------CVKEIGLLKQLN--------HPNIIKYLDSFIED--NELNIVLE
... ...| |.|  |||...  .     . || |......|   .  |.         .|| ..|.|.        ||||.|..| | ..  | . |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LADAGDLSQMIKYFKK------QKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITAT------------GVVKLGDLGLGRFFSSE---TT
. . |||.| ||  ||       |. ..|  . ..| |....  ..|.....||||||.|. |.              ||.|..| |........     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

AAHSLV------GTPYYMSPERIHENG----YN-FKSDIWSLGCLLYEMAALQSPFYGDKMNLF-----SLCQK---------IEQCDYPPL-PGEHYSE
 ... |      |||.||.|. ....|    |. .|.|||||||..|||   . |||. .. ..     .| ..          .. ..|.  .. . |.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

KLRELVSMCICPDPHQR
....| . ... |. .|
ECKDLIRRMLQYDEKDR
Kinase NEK6.AA NEK2 79-330 34 1.7e-66 222.93 In-house 1-310 (319) Show / Hide 
Range on Protein: 79-330
Range on HMM: 1-310/319
Sequence Identity: 34% (107 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFI--EDNELNIVLELADAGDLSQMIKYFKKQKR
 .. . ||.| |  ..|     | |  . |  .  . |. | .|  | |. .|.|| ||||..| |  |  .   | || |    ||||||||  .|...
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEIC-YGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQ

LIPERTVWKYFVQLCSAVEHMHS---------------------RRVMHRDIKPANVFITATGV------------------------------------
 ..|  .|. . |||.|    |                      . ..||||||||.|  . .                                     
YMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYS

---VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELV
   ||||| || |    .|  ||. |||||||||| .|   || ||||||.|||.|||.||  || .   |   |  || |  . ..| . ||. | |..
QVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQA--TNQAQLQEKIKQGHFRRIP-YQYSRHLNEII

SMCICPDPHQRPDI
.  |  |. .|| |
HFMINVDHYHRPSI
Kinase NEK6.AA NEK4 79-342 35 3.9e-63 216.05 In-house 1-257 (257) Show / Hide 
Range on Protein: 79-342
Range on HMM: 1-257/257
Sequence Identity: 35% (94 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSF-IEDN-ELNIVLELADAGDLSQMIKYFKKQKR
... | .|.| . ||.      |.|   .||..     . . |..  .|. || || ||||..| .|. ||..  | ||.   . ||| .  |  ..   
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFL-KNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLK--QQKNQ

LIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA
...|. |   |||   |   || ....||| |  |.|.| . ..|.||.|. |        |  ..|||||||||      |..||||||||| .|||. 
FLEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMIT

LQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMHI
|   |    ||  ||  .| |   ||.|   ||. | .||   .   | .|| |    .. ..  |
LKHAFDAKDMN--SLIYQIIQGQPPPMP-PNYSQDLQNLVYQMLEKQPTKRPSI---FDIFQMPYI
Kinase NEK6.AA TyrKc 79-337 22 4e-31 110.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 79-337
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL--NHPNIIKYLDSFIED-------NELNIVLELADAGDLSQMIK
 . .||.|.|.| ||||.|      .|| |...         |.|  .|. ....|  .||||.. .   ...         | ||.|... ||| . ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

YFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSE--------TTAAHSLVGTP-----YYMSPERIHEN
. ...   .. ..  .. .| ..  |. ||... |||.   |. ... ..|| .| || |.  ..        .  . .  |.        |.|| | ..
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYNFKSDIWSLGCLLYEMAALQSPFYGD----KMNLFSLCQKIEQCDYPPLPGE-------HYSEKLRELVSMCICPDPHQRPDIGYVHQVA
 ...|||.|| | ...|.  .  . | .    .|. . . ....| ...| | .       . .... .. ..|   ||..||    .|.  
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase NEK6.AA Pkinase_Tyr 79-274 28 1.2e-25 87.47 Pfam 1-207 (270) Show / Hide 
Range on Protein: 79-274
Range on HMM: 1-207/270
Sequence Identity: 28% (60 aa)

FQIEKKIGRGQFSEVYKATCL----LDRKTVALKKVQIFEMMDAKA--RQDCVKEIGLLKQL-NHPNIIKYLDSFI-EDNE--LNIVLELADAGDLSQMI
 .. ||.|.|.| ||||.|.      .. .|| |..   |  . ..  |.|  .|. ..||| .||||....   . ..    . ||.|..  |||    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL---

KYFKKQ---KRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF--SSET-TAAHSLVGTPYYMSPERIHENGYNFKS
.| .|.   |. ..  .  .. .| ... |. .|..  |||.   |. .| ..||| .| || |     ..  .....       |.|| |... .. ||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS

DIWSLGCLLYEM
|.|| | |..|.
DVWSFGVLMWEI