Gene PLK2 (Human)

PLK2

Species: Human
Alias: PLK2, SNK
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 5p12-q11.2,

Classification

Group: Other
Family: PLK
Subfamily: PLK2

Sequence

Name Sequence Type Origin Length Description Download
PLK2.NA RNA Sugen Kinome 2955 None Fasta, JSON
PLK2.AA Protein Sugen Kinome 685 None Fasta, JSON
PLK2.kin_dom Protein Kinase Domain Sugen Kinome 253 None Fasta, JSON

Protein domain

Protein domains of PLK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PLK2.AA PLK2 82-334 75 1.1e-231 753.84 In-house 1-257 (257) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-257/257
Sequence Identity: 75% (194 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSR----RSMAHILKARKVL
|||||.|||||||.||||||.....|||.||.|||||||||||||...|||||| |.|.|.|||.|.|||..|||||||||||    .||||..|.|..|
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

TEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGR
||||||||.|||||||.|||.|.|.||||||||||||..||.|.|||||||||||.||..||.||||||..|||||.|||.||||||||||.|||||.||
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNRQGHSCESDIWALGCIMYTMLCGR

PPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
|||||.||||||||||...|.||..|..||.||||.|||..||||||||.|||||||
PPFETANLKETYRCIRHNHYHMPTHLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase PLK2.AA PLK 82-334 59 5.3e-192 630.4 In-house 1-258 (258) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-258/258
Sequence Identity: 59% (153 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR-KVLTEP
|.||..||||||||||||||. ...|||.|..|.|...|||||||...|||.|| |||...|.|.|.|||.||.||.||||..||..|..|.| |.||||
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVL--NKQGHGCESDIWALGCVMYTMLLGRP
|||||..|||.||||||...|.||||||||.|.|. |..|.||||||.|||. ..|..|.|||||| .||||  |||||..|.|.|.|||.|||.| |.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETTNLKETYRCIREARYTMPSS--LLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
|||| ..||||..|....|..|..  . ..||.||..||..||..||..| |..|.||
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase PLK2.AA PLK-Unclassified 82-334 50 2.6e-134 452.5 In-house 1-264 (264) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-264/264
Sequence Identity: 50% (132 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR-------
| ||. ||||||||||..... ..|.||||||| |   |  .|.|   ||..|  ||||..|.|.| ||| ||.|||||||.  .. ...| |       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVL-NKQ-GHGCESDIWALGCVMYT
|.|||.||..|. ||| .|||||   | |||||||| |.|. ||.| .|||||..||  . ...|||||||| .||.| .|. ||. |.|.|..||. ||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

MLLGRPPFETTNLKETYRCIREARYTMP--SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
.| |.|||||   | ||. |.  .|  |  . .   || || . |. ||. ||..| |  |.|.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase PLK2.AA PLK1 82-334 52 2.8e-130 430.57 In-house 1-253 (253) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-253/253
Sequence Identity: 52% (134 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPE
| .|. |||||||.|||..|   ..|.|.|..| | . |.|||.|. .||..|| |||.|.|.|.|.||||.|.||.|| |.|||.  . | || .||||
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

VRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFE
 |||..||| | .|||...|.|||||||| |.|. ...|.|||||| ..|    |..|.||||||. ||||||.||  | |||..||.||..|.|.||||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFE

TTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
|  |||||  |... |..||.. .||..|| .|| ..|. ||  . ... .||
TKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase PLK2.AA S_TKc 82-334 31 1.2e-98 334.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSR--RSMAHILKARKV---
|  ....|||.|.|.|  ..   ....| |||.          |.| .||....  ||...|..| .|.| ...|. .|||.    .. ...| |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGC-ESDIWALGCVMYT
   ..| ..|.|..||...|.|.|.. |.|||||  | ...|  ..|..|||||..|       .|.||||.|..||||   |.|. ..|.|..||..| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIR-------HDFF
|| |.|||.  ....... |.            .||..|  .| |.||.||.  .. .       | .|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PLK2.AA CAMK 87-334 20 5.8e-94 303.14 In-house 1-425 (425) Show / Hide 
Range on Protein: 87-334
Range on HMM: 1-425/425
Sequence Identity: 20% (86 aa)

VLGKGGFAKCYEMTDLTNN------------KVYAAKIIPHSRVAK-------------------------PHQREKIDKEIELHRI-------LHHKHV
.||.|.|.| .. ..  ..            . .|.|||. ... .                         |. |... .|||...        |.|...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQFYHYFED-------------------KENIYILL---EYCSRR----SMAHILKAR---------------KVLTEPEVRYYLRQIVSGLKYLHEQEI
...|...||                   ....|. .   ||||       .   ....               . .|| |.|.| |||.|...|.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLKLGNFFINEAM-----------------ELKVGDFGLAARLEPLE-----------------------HRRRTICGTPNYLS-PEVLNK------
 |||||. |  ... .                  .|. |||.|....| |                       .  .| |||| | . |||||.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------QGHGCESDIWALGCVMYTMLLGRPPFETT-------------NLKETYRCIREARYTMPSSLLAP------------------------AKH
        ...| ..|.|..|...|.|| |.|||.               |..|... |....|..|.. . |                        .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIASMLSKNPEDRPSLDDIIRHDFF
|| .|| ..||.|...... .| ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PLK2.AA AGC 82-334 21 1.4e-89 231.08 In-house 1-395 (395) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-395/395
Sequence Identity: 21% (85 aa)

YCRGKVLGKGGFAKCYEMTDL------TNNKVYAAKIIPHSR--------VAKPHQREK-------IDKEIELHRILH----------HKHVVQ-FYHYF
.   ||.|||.| |.|   .       ...|.|| |..  ..          .  ..|        . .| .    ..          |  .|.  .. |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDKEN--IYILLEYCS----------R-RSMAHILK--ARKVLTEPEVRYYLRQ-------IVSGLKYLHE-QEILHRD-LKLGNFFINEAMELKVGDFG
.||..  .|...||..             .. |. .   .....|...|.|. .       ||..| |||. . | ||| ||. |  ..|   .|  |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAARLEP--------------------------------------------------LEHRRRTICG--TPNYLSPEVLNKQGHGCESDIWA--LGCVMY
|. ..                                                     ..|  |.||  ||.|..||.|    .| . |.|.  |||.||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

TMLLGRPPFETTNLK----------ETYRCIR------EARYTMP----------SSLLAPAKHLIASMLSKNPEDRPS----------LDDIIRHDFF
 || |.|||   |            |..  |.      . . ..|          ...   ||.||  .| |.||.|.            ..| .| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PLK2.AA Pkinase 82-334 28 2.2e-87 301.42 Pfam 1-293 (293) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-293/293
Sequence Identity: 28% (83 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID-KEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRR----SMAHILK--AR
|..|...|.|.|...|. ..  ..|..| |||. ..  .  .....   ||.... |.|...|..|..|||| .||. .|||       . .....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KVL--TEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMEL----KVGDFGLAARL-EPLEHRRRTICGTPNYLSPEVLN-KQGHGCESDIWAL
...  .| |.. |..||..||.|.|.. |.|||||. |..|.. ...    |..|||||. . .   .   |.||||.|..|||..  |..| ..|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVMYTMLLGRPPFETT------NLKETYRCIREARYTMPSSLL---------------------APAKHLIASMLSKNPEDRPSLDDIIRHDFF
||..| ||.|||||         . .. .. |.....  ... .                      ..|..| ..| |.|..||. ..|  |..|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PLK2.AA CAMKL 82-334 28 1.8e-83 266.22 In-house 1-297 (297) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

YCRGKVLGKGGFAKCYEMTD-LTNNKVYAAKIIPHSRVA-KPHQREK-----------IDKEIELHRILH---HKHVVQFYHYFEDKEN------IYILL
|  ||.||||.|.|    |. .|... .| |||  ..   .|. . .           | .||.... |.   |......|. .|..|.      ||. .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCSRRS--MAHILKAR----KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAM--ELKVGDFGLAARLEPL----EHRRRTICGTPNYL
||||  .  . . ....    . ..|.| | | |||||...|.|.. | |||.|. |  . | .   .|. |||...  .|     ..  .| ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEVLNK--Q-GHGCESDIWALGCVMYTMLLGRPPFETTNLK-------ETYRCIREARYTMP--SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
.||....  .  .| . |||..| ..|.|. |. ||.  ...       . |. |..  | .|  ...  ....|| .|| .|||.||....| .| ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase PLK2.AA SAK 82-334 40 3.4e-78 265.89 In-house 1-254 (254) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-254/254
Sequence Identity: 40% (102 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR-KVLTEP
|  ...|||||||  |    .   .  | |.|    . |    ... .|.|.|  | |  ... | ||||   .|. || |    |   .| | .. || 
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

EVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPF
| | ...||| |. |||  .|.|||| | |  .   |..|. |||||. |.  . .  |.||||||.|||.  .  || .||.|.|||..||.|.|||||
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPF

ETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
.|   |.|   .  | | ||. |   |. ||  || |||..| .|. .. | | 
DTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase PLK2.AA MARK 82-334 32 2.6e-75 245.67 In-house 1-262 (262) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-262/262
Sequence Identity: 32% (86 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFE--DKEN-IYILLEYCSRRSMAHILKAR--KV
|  .|..|.|..|| .  ...  .. .| ||..  .  .|......  |||... |.|.......|..|  .... ||. .||.|. .. . .||.    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAM--ELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQG-HGCESDIWALGCVMYTM
|.|.| | . |||||...|.|.. | |||.|. |  | | .    |  |||.... .| . .  | |||| | .||...|.   | . |||.|| |.|.|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPP-GQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LLGRPPFE--TTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
. |. ||.  | ..|| |. |.  .|. |. . . ...|| ..|  |||.||....| .| ..
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase PLK2.AA ULK 82-334 26 3e-68 233.04 In-house 1-324 (324) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-324/324
Sequence Identity: 26% (86 aa)

YCRGKVLGKGGFA-KCYEMTDLTN---NKVYAAKIIPHS-RVAKPHQRE------KIDKEIELHRILH---HKH--VVQFYHYFEDK--ENIYILLEYCS
||  ..|||| |. | |. ..  .   |...|.|.|. .    |....|      ....||.. ..|.   |..  .|..|..||..   |||| .||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

RRSMAHILKARKV---------LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEA------------MELKVGDFGLAARLEP---LEHRRRT
     ...| .|          |.|.|.. ...||..|.|.||.. | |||.|. |  |..               ||..|||.|  ..     .  . |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IC------GTPNYLSPEVLN----KQGHG-CESDIWALGCVMYTMLLGRPPFETTNLKETY----------------RCIREARYTMPS---SLLAPAKH
..      ||| | .|..|.    .. ..  ..||| |||..| || |..||..    ..|                 . .  .. .|.    .    | 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIASMLSKNPEDRPSLDDIIRHDFF
||  || ....|| | ..|. | .|
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase PLK2.AA TyrKc 82-334 21 1.9e-16 43.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 82-334
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRIL--HHKHVVQFYHYFEDK-------ENIYILLEYCSRRSMAHILK
   ||.|| | | . |. |        | | . ..       || . .|... . |  ||...|..| .  ..       | ..|..||..  .  . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ARKV-LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL--------EHRRRT-ICGTP----NYLSPEVLNKQGHG
...  |. ..  ..  || .|  |||.. . ||||   |  ..|    |..||||.  ..            | ..  .|        ..||..|.    
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

CESDIWALGCVMYTML-LGRPPFET-----TNLKETYRCIREARYTMPSSLL-------APAK--HLIASMLSKNPEDRPSLDDIIRHDFF
 .||.|. | .|. .. .| .| .       . .| ...... .. ..           .|..   .. .    .|||||.  .|  |..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PLK2.AA Pkinase_Tyr 137-334 26 5.8e-15 51.3 Pfam 60-270 (270) Show / Hide 
Range on Protein: 137-334
Range on HMM: 60-270/270
Sequence Identity: 26% (58 aa)

L-HHKHVVQFYHYFE-DKEN--IYILLEYCSRRSMAHILKA----RKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAA
| ||...|..|     ..|   ||| .||.   .. . |..    .. || ..   . .|| .|. ||... . ||||   |  ..| .  |..||||| 
LGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

RL-------EPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLL-GRPP-FETTNLKETYRCIREARYTMPSSLLAPAK--HLIASMLSK
 .          .. .  |  .    .||..|      .||.|. | .|. ..  |. | ..     | |. | | .| ||   ..|..  .|. .   .
DIYNDDYYYRKRGGGKLPIKWM----APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHY

NPEDRPSLDDIIRHDFF
.|||||.  .|  | ..
DPEDRPTFSEI--HEQL
POLO_box PLK2.AA POLO_box 510-573 33 4.3e-25 94.48 Pfam 1-74 (74) Show / Hide 
Range on Protein: 510-573
Range on HMM: 1-74/74
Sequence Identity: 33% (25 aa)

YSNKYGFGYQLSDHTVGVL-FNNGAHMSLLPDKK-TVHYYA--ELGQCSVFPATD------APEQFISQVTVLK
|..|||..||||..||.|. || . .. |.|..| .|.|..  . .|....| ..       ||.. ...|.||
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK
POLO_box PLK2.AA POLO_box 606-677 34 5.5e-27 100.78 Pfam 1-74 (74) Show / Hide 
Range on Protein: 606-677
Range on HMM: 1-74/74
Sequence Identity: 34% (26 aa)

LKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYIN--EDRISTTFRLTTLLMSGC-SSELKNRMEYAL
.... ..|.....||.||||..||||||.|.. . |..|||.  ... ..|..|.|.| .|| ...|.....|. 
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMK-YAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK