Gene PCTAIRE3 (Human)
PCTAIRE3
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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PCTAIRE3.NA | RNA | Sugen Kinome | 3212 | None | Fasta, JSON |
PCTAIRE3.AA | Protein | Sugen Kinome | 504 | None | Fasta, JSON |
PCTAIRE3.kin_dom | Protein Kinase Domain | Sugen Kinome | 282 | None | Fasta, JSON |
Protein domains of PCTAIRE3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | PCTAIRE3.AA | PCTAIRE | 174-455 | 79 | 4.5e-243 | 813.81 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-291/291 Sequence Identity: 79% (230 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVK |.|||||||||||||.|.|||||.||||||||||||||||||||||||||||.|||||||||||.|||...|||||||.|.|||||.|.|||.|.||||| YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNVK IFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPG .|.|||||||||||.||||||||||||||||||||||||||||||||||||||||.|||||||||||||.|||.|||.|||||||||.|||.|||||||| LFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFPG ST------VKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLD---TDGIHLLSSLLLYESKSRMSAEAALSHSYF || ||..||.|||.||||.|.|||||....|||||.||.|..||||||||||| .....||..||.||||.|.|||.|..|.|| STDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF |
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Kinase | PCTAIRE3.AA | PFTAIRE | 174-455 | 60 | 2.3e-191 | 642.06 | In-house | 1-287 (287) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-287/287 Sequence Identity: 60% (174 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVK |.||.|||||.||||.||.|.... .||||||||. |||.|.|||||.||||||||||||.||| |||.. ||.||||.. ||.||.| . . | ..||. YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNVR IFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPG |.|||||||.|||.|..|||||||||||| . |||||||||||||||||..|||.||||||||||||||||||||| .|||||||| || .|.|.||| LFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFPG S-TVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFP--CYLPQPLINHAPRLD--TDGIHLLSSLLLYESKSRMSAEAALSHSYF .. . | .||..||||||.|||||. . ... . |. | |..| . ||.. .. |.. .| .| . |.||..|..| || MKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF |
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Kinase | PCTAIRE3.AA | CDK5 | 174-455 | 56 | 2.3e-180 | 575.11 | In-house | 1-287 (287) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-287/287 Sequence Identity: 56% (163 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNV | |..|.|||||.||.|.| | |. .||||..||. | || |.|||||..||| ||| ||| ||| ||... ||||||..| ||| |.| |. |.|| . YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII KIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMA-TGRPLF | ||.|||.|||.||....||||||||||||| .||||||||||||| .| ..|| |||||||||||||.|| |||.|||| .||| ||| .||||| KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF PGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFR--TYSFPCYLPQP-LINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF ||. |...| .||...|||.|..||..| .... .| | ... . .. |.|| | ||. .| .. . |.||.||| | || PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF |
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Kinase | PCTAIRE3.AA | CDK | 174-455 | 48 | 2e-176 | 569.1 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-284/284 Sequence Identity: 48% (154 aa) YVKLDKLGEGTYATVFKGRSKLTE-----NLVALKEIRLEH-----E-EGAPCTAIREVSLLKNLKHANIVTLHDLIHTD-----------RSLTLVFEY | ||.|.|||||..|.|.|.|.| ..||||.||.|. | || |.|||||.||||.| |.|||.||| .||. ..|..|||| YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY LDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGE-----LKLADFGLARAKSV------PTKTYSNEVVTLWYRPPD .| |||.|.| .| .|.||||||.|||...|.||||||||.|||..|| ||.||||||||... |..||..||||||||.|. MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE VLLGSTEYS--TPIDMWGVGCIHYEMAT---GRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSL .||||..|| ||||||.|||| .||.| ..|||||.. . |..|||..|||||..||||| . .. .||... LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM LLYESKSRMSAEAALSHSYF | |. | |.|||.||.| || LCYDPKKRISAEQALQHPYF |
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Kinase | PCTAIRE3.AA | CDC2 | 174-455 | 50 | 1.1e-153 | 476.01 | In-house | 1-301 (301) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-301/301 Sequence Identity: 50% (152 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGA---PCTAIREVSLLKNLK-HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLD-HCG--NL | |. |.||||| |.|.. . | .|||| ||||.|. | ||||| |.||.|| | |||.||| || ..| .|||||| |||.|.| . YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH MSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYS--NEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEM |. ..|| .|.|.|.|...||.|.|.||||||||.||.. |..|.|||||||| ..| .|| ||||||||.| .|||. ||||.||| .||| .|| MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM ---ATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPR---------LDTDGIHLLSSLLLYESKSRMSAEAALSH .| .|||.| ..| ||| ||||.|.|||||| . .. . .||.. || | .. |. || .|| ||...| |. | ||..||.| FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKN-TFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQH SYF || PYF |
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Kinase | PCTAIRE3.AA | CMGC | 174-455 | 27 | 2.7e-137 | 454.19 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-513/513 Sequence Identity: 27% (139 aa) YVKLDKLGEGTYATVFKGRSKLTE--------------NLVALKEIRLE----------HEEGAPCTAIREVSLLKNLK-----------------HANI | ...|.|||||..|.|.| |.|. ..||.| |... ...| |..|.||...||.|. | || YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI VTLHDLIHTDR-----------------SLTLVFEYLDSDLKQYLDHCG---------NLMSMH-----------NVKIFM------FQLLRGLA--YCH |.|.| .... .| |||||.| ||.||.... .| | |.| || .|.||||. ||| VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH HRK--ILHRDLKPQNLLINERGEL--------------------KLADFGLARAKSVP---------------------TKTYSNEVVTLWYRPPDVLLG .. |.||||||.|.|||...|| |..||||||. ... ...|...|||.|||.| .||| SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG STEYS---------TPIDMWGVGCIHYEMATG--------RPLFPGSTV-----------KEELHLIFRLLGTPT---------------EETWPGVTAF ...|. ||||||.|||| .|| || .|||||.. . |..||..||||| ||.||... WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL SEFRT-------------YS------------FPCYLPQPLINHAPR-----------------------------------LDTDGIHLLSSLLLYESK .. . .| || . |.|. | |. .| ..|.||. .| |. . PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD SRMSAEAALSHSYF |..|| ||.| || KRITAEQALQHPYF |
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Kinase | PCTAIRE3.AA | CDK7 | 174-455 | 38 | 3.4e-111 | 297.44 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-288/288 Sequence Identity: 38% (110 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIR-----LEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMS | |....|||..|||.|.. . |. || |.|. | . | |||||. .|. ..| |.. | | . .. |||...| || .. YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT MHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGR ..| .| ..|.|| ||| |||||||| |||.|| |.||.|||||||. | . |. ||| ||| | | | | | .||| |||| | PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV PLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTY-SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF | .|| | ||. |||||||.||..... .. . .|| | || . | ..|.. ... . |... .|.. || PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF |
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Kinase | PCTAIRE3.AA | PITSLRE | 174-455 | 39 | 6.8e-98 | 331.52 | In-house | 1-295 (295) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-295/295 Sequence Identity: 39% (116 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE---HEEGAPCTAIREVS-LLKNLKHANIVTLHDLI--HTDRSLTLVFEYLDSDLKQYLDHCG--- ...|.. .|||| |.... |.|. |||| . .| || | |..||.. .|. |.| |||.. . . . .|.||.. ||| .. FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN NLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEM . .| .| ||||| .. | .|.||||| |||.. | ||..|||||| | | |. ||||||| | .|||. .||||.||| |||| |. QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF ATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS-FPCYLPQPLINHAP---RLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF |..|||.|. .... || ..||||| |||.| . .. || | . | .. | .. | || .| | | |..|..|| | .| ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF |
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Kinase | PCTAIRE3.AA | CDK4 | 174-455 | 44 | 1.1e-94 | 320.88 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-290/290 Sequence Identity: 44% (131 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEE--GAPCTAIREVSLLKNLK---HANIVTLHDLIH---TDR---SLTLVFEYLDSDLKQYLD |... .||| | ||.. |. | . |||| .| || | | |||.|... |. |.||| | | | ||| .|.||| | ||..||| YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD HCGN-LMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCI | |. .| |.|||||. . | | ||||||||.|.. |..||||||||| | .. . ||||||| | ||| |. | ||.||| |||| KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMALTPV-VVTLWYRAPEVLLQSY-YNTPVDMWSVGCI HYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF || ||||.|. |. || || . |.|.|. || . .|| . |.|. | .. |. || | |. . ||||...|.|.|| FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP---WDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF |
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Kinase | PCTAIRE3.AA | S_TKc | 174-455 | 28 | 5.7e-94 | 319.42 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-231/231 Sequence Identity: 28% (84 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDS---DLKQYLDHCGNL---- | .|.|.|.|....|.|.| | | .||.|.|. ....||...||. .| |||.|.| ... .| .|.||.| ||..|....| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -MSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST-PIDMWGVGCIHYEM .. .. .| |....|.||| ..|.||||||.|.|..| ..|..|||||| . ..|.||..| || |.. ..|.| .||| ||| PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM ATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALS-------HSYF ..|.|.|| .....|...| . ....... .| .. . |..| || | .| LCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | PCTAIRE3.AA | Pkinase | 174-455 | 32 | 2.1e-88 | 304.81 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-293/293 Sequence Identity: 32% (99 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEG-APCTAIR--EVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDS-----DLKQYLD---H |... |.|.|....|.|.. | |. .||.|.|...||. . |..| |....|.|.| |||.|.| ...... .|.||.. ||. |. | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH CGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGEL----KLADFGLARAK-SVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGV .. ..|.. .| .| |.||||.||| ..|.||||||.|.||...|.. |..|||||. . . .. ..|.||..| |..|...|....|||.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GCIHYEMATGRPLFPGS----TVKEELHLIFRLLGTPTEETWPGVTA---FSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAAL ||| |||..|||.|||. . .....|.| .|.|... || |. ||. . . . .... .........| . |.| .|| .| GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL SHSYF | .| QHPWF |
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Kinase | PCTAIRE3.AA | CRK7 | 174-399 | 36 | 1.9e-85 | 290.15 | In-house | 1-281 (343) | Show / Hide |
Range on Protein: 174-399 Range on HMM: 1-281/343 Sequence Identity: 36% (102 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE----EGAPCTAIREVSLLKNLKHANIVTLHDLIHTD---------R-SLTLVFEYLDSDLKQY | ... ||||| | | . | |. .|||| .|...| || | |||||. .|. |.|.|||.|.. . . . | .|||| | || YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL LDHC-GNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPT--KTYSNEVVTLWYRPPDVLLGSTEY-------- |. | ..| || ||| |..||| ...||||.| |.|.| .||.|.||||||| . | | |.||||||| ||| ..| LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE ------------------------------STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVT . ||||..||| | .|..|.|.|. . | .|... |.|. . || |. LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVM |
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Kinase | PCTAIRE3.AA | Pkinase_Tyr | 174-319 | 30 | 1.6e-16 | 56.56 | Pfam | 1-160 (270) | Show / Hide |
Range on Protein: 174-319 Range on HMM: 1-160/270 Sequence Identity: 30% (50 aa) YVKLDKLGEGTYATVFKGRSK----LTENLVALKEIRLEHEEGAPCTA------IREVSLLKNL-KHANIVTLHDLIH-TDRS--LTLVFEYLDS-DLKQ ... ||||| . .|.||. | |. || | .. ||| . .||....|.| .| ||| |. . ... . .|.|| ||. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD YLDHC---GNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARA || .. .|. . .| .|..| . ... |||| | |..| . | .||||||. YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD |
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Kinase | PCTAIRE3.AA | TyrKc | 174-455 | 21 | 9.8e-13 | -16.77 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 174-455 Range on HMM: 1-280/280 Sequence Identity: 21% (67 aa) YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAI-REVSLLKNL--KHANIVTLHDLIHTD-------RSLTLVFEYLDS-DLKQYLDH ....||||| . .|.||. | || | .. .. .. || .....| .| ||| |. . .. | .|.|| . |||.|| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK CGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVP------TKTYS-----NEV--VTLWYRPPDVLLGSTEYS ... .| |..| .| .| |.... |||| | |..|.. | .||||.|. ...|. .. . . .| .. ... HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT TPIDMWGVGCIHYEMAT-GRPLFPG--------STVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYES | | | | .|. | | . || . | | . .|. | . | . .. .. . .. .. TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MS---------------------FVCCPDEMYQIMKQCWHEDP KSRMSAEAALSHSYF ..| . .. |..| EDRPTFSEI--HECF |
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Kinase | PCTAIRE3.AA | CRK7 | 431-455 | 40 | 0.000288 | 10.39 | In-house | 319-343 (343) | Show / Hide |
Range on Protein: 431-455 Range on HMM: 319-343/343 Sequence Identity: 40% (10 aa) LLSSLLLYESKSRMSAEAALSHSYF || .| . | |..|| .| | .| LLDKMLCLDPKKRFTAEECLQHDWF |