Gene NIM1 (Human)

NIM1

Species: Human
Alias: NIM1, MGC42105
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 5p14,

Classification

Group: CAMK
Family: CAMKL
Subfamily: NIM1

Sequence

Name Sequence Type Origin Length Description Download
NIM1.NA RNA Sugen Kinome 2326 None Fasta, JSON
NIM1.AA Protein Sugen Kinome 436 None Fasta, JSON
NIM1.kin_dom Protein Kinase Domain Sugen Kinome 252 None Fasta, JSON

Protein domain

Protein domains of NIM1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NIM1.AA NIM1 74-325 71 4.6e-252 748.7 In-house 1-258 (258) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-258/258
Sequence Identity: 71% (185 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILD--KTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEP
||..||||.||||.||||.|.||||||||||.|  |||.||||||.|||||..||..|||||.|||||||||...|||||||.||||...|..||||.|.
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

ESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKK----GEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTG
..|.||.||||||||||...|.|||.|||||.||||.||||||||||...|.    ..|||||||||||||||||.||||||.|||.||||.|||||.||
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

TMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM
.||||||||.|.||.||.|.|..|..||.||||||||.|..|||.||.||..||..||
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase NIM1.AA CAMKL 74-325 40 5.1e-142 456.11 In-house 1-297 (297) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-297/297
Sequence Identity: 40% (121 aa)

YRIRGEIGSGNFSQVKLGIH-SLTKEKVAIKILD--KTKLDQKTQRL-----------LSREISSMEKLH---HPNIIRLYEVVETLSK------LHLVM
|||  ..| |.|..|||..| ..|.|||||||.|  |...|.....            . |||. |..|.   |||||.||||.|| ..      ..|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAGGGE--LFGKISTE----GKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNT--CVKVGDFGFSTVSKK-----GEMLNTFCGSPPYA
||..|||  || .|  .    |...|.| . .| ||||||...|.. |.|||.|.||.  ..|    .|. |||||.  ..     |..|.||||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFRD--EHYIGIYVDIWALGVLLYFMVTGTMPFRAETVA---------KLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM
|||.| .  ..|.|  ||||..||.||.||.|..||...|..         ..|. .. . . ...||| .|..|||. ||  |..|. |. |||..||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase NIM1.AA MARK 74-325 47 1e-125 412.84 In-house 1-262 (262) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-262/262
Sequence Identity: 47% (124 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQ-KTQRLLSREISSMEKLHHPNIIRLYEVVE--TLSK-LHLVMEYAGGGELFGKISTE--GK
|..  .|| |....|||..| .|..||||||..|.||.  .. . . |||. | ||.|||||.|..|.|  | .. ..|.||||.||||.. |     |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNT--CVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMV
|.|.| . ||.||||||. .|.. |.|||.|.||.   .|.   .|  |||||.  . |..||||||.|||.|||.|  . | |  ||||.|||.|||||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGTMPFRAET--VAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM
.|. ||.. |    .|.| || | |..|.|||  |. ||. .|.  | ||  |. ||...||
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase NIM1.AA CAMK 79-325 26 1e-121 394.2 In-house 1-425 (425) Show / Hide 
Range on Protein: 79-325
Range on HMM: 1-425/425
Sequence Identity: 26% (115 aa)

EIGSGNFSQVKLGIHSLTK------------EKVAIKILDKTKLD--------------------------QKTQRLLSREISSMEK-------LHHPNI
..|.|.|..|||.|| .|.            .||||||.||.||.                          .|... . |||. | |       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYEVVE------------TLSK--------LHLVM---EYAGGGEL----FGKISTE---------------GKLSEPESKLIFSQIVSAVKHMHENQ
|.|||| |            | ||        ...||   ||. ||||    | .|                  |...| | . .| ||.|||...|.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKAENVFYTSNT-----------------CVKVGDFGFSTVSKK------------------------GEMLNTFCGSPPYAA-PELFRD-----
|.||||| ||. ...|                   .|. ||||... ..                        |....||||.|.|.| ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EHYIGIYVDIWALGVLLYFMVTGTMPFRAE-------------TVAKLKKSILEGTYS-VPPH-----------------------VSEPCH
        . |.|  .|.|..||.||.|..|..||...             .  .|.. |..| |.  ||.                       ||. | 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

RLIRGVLQQIPTERYGIDCIMNDEWM
 |||. ||  |..|. |. ..|..||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase NIM1.AA AMPK 74-325 46 5.9e-116 345.71 In-house 1-254 (254) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-254/254
Sequence Identity: 46% (117 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKL-DQKTQRLLSREISSMEKLHHPNIIRLYEVV-ETLSKLHLVMEYAGGGELFGKISTEGKLSEP
| |   || | |  ||.|.| ||.||||||||.|.|. ||...  ..|||. . .. ||.||.||||. || . . .||||. |||||  |   |.|.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

ESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPF
|..  | ||.|.|  .|.. | ||||| ||.    | ..|. ||| | . |.||.| | |||| |||||.     | | .||||  || || |. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

RAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM
  | ...| | |..| |..| ..|. .. ||.. ||  |..|. |. |.|..| 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase NIM1.AA QIK 74-325 42 1.8e-109 369.95 In-house 1-272 (272) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-272/272
Sequence Identity: 42% (115 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGK------
| |   || |||  |||. |  ||.||||||.||..||..    . ||.  |  | ||.||.||.| || . . .|.||. .||.|  .   |.      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVD
              ..|.| . .|.||.|||.. |. .|.||||||||.   .|  .|. |||||  .|.|..|.|.||||||||||.|  . | |  ||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

IWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM
|| .||.|| .|.| .||  .|. .|....|.| . .|. .|. |  |||  |   |. || |. |..  ||
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase NIM1.AA NuaK 74-325 43 1.1e-99 262.71 In-house 1-252 (252) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-252/252
Sequence Identity: 43% (109 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQ-RLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPE
|..    |.| .  |||..   |  .||||   | | . .   .   |||  |  |.||.||  ||| |  .|. .||||| ||||.  ||  ..|.| |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

SKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFR
 . .| ||||||   | ..|.||||| ||.    |  .|. ||| | . .....|.|||||| || ||    . | |  || |.|||||| || ||||| 
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

AETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM
 .   .|.| | .| |  |.. |. |  |||  |.  |. |  |  | .  |.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase NIM1.AA S_TKc 74-325 31 1.1e-90 308.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-231/231
Sequence Identity: 31% (84 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGG--GELFGKISTEGK----
|.|  .||.| |..|....|  |...|||||..         . . |||. ..| |||||..||.| .. ..|..||||..|  |.||  |   |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI-YVDIWALGVLLYFM
  ..| . . .. ||..|....|...||||||| ||.. ..  ..|..|||....       .||||.| | |||..      |   .|.|..|..|| |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

VTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMN-------DEWM
..|  ||.  ..... | |.          |...  .||. ||  |..|...  ...       ..|.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NIM1.AA Pkinase 74-325 31 9.9e-85 292.59 Pfam 1-293 (293) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSR--EISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGG----ELFGKIS--TE
|.| . ||||.|..|....|  | ..||.||..| . . . .. . |  ||. | .|.||||.|||...|. .....||||..||    .||  ||   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--SEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCV----KVGDFGFSTV--SKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWAL
|..  || | | .. ||.......|.. ||||||| ||... .|  .    |..|||.. .    ... ..||||.|.|.|||. |.  |.|  ||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYFMVTGTMPFRAE----------TVAKLKKSILEGTYSVPPHVS-----------------EPCHRLIRGVLQQIPTERYGIDCIMNDEWM
|..|| |..|  ||. .           ... .. .|.  .. .  .|                 |.|  .|.. |.. |..|.....|....|.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase NIM1.AA TSSK 74-325 34 5e-76 249.01 In-house 1-289 (289) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-289/289
Sequence Identity: 34% (100 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEK----------------VAIKILDKTKLDQK-TQRLLSREISSMEK-LHHPNIIRLYEVVETLS-KLHLVMEYAG
|     ||.|... |... .  .| |                ||||| |..|     ... | |||. | | |.|||||..||  || . |  .||||| 
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGELFGKISTE------GKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGE------MLNTFCGSPPYAAPELF
.| |. .| .       | |.|..... |.|.|||||..|   . ||||| ||..   . ..| .||||. . ....      .. |||||  ||||| .
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

RDEHYIGIYVDIWALGVLLYFMVTGTMPFRA--ETVAKLKKSIL--EGTYSV--PPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM
|   | .  .|.|..|| || ||.|.|||      . |. . .   . ..     ...|. |  |||  ||. |..|. |. |....||
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase NIM1.AA MELK 74-325 39 1.4e-74 254.05 In-house 1-254 (254) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-254/254
Sequence Identity: 39% (100 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPES
| .  |||.| |..|||  | || ..|||||.|| .| .   |.   |. .. .|.| .| .|| ..||  |. .||||  |||.|  |  . .|.| |.
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLPRVKT-EMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEET

KLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEM----LNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTM
. .| |||||. ..|     ||||| ||.... .  .|. |||.   . ||..    |.| |||| |||||| .  .|||   |.|..|.||| .. | .
RHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM
||  . .  . | |. | | .|...|    .|.| .||  |. |  .  ..| .|.
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase NIM1.AA RSK 74-325 31 1.4e-73 250.8 In-house 1-278 (278) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-278/278
Sequence Identity: 31% (89 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQK--TQRLLSREISSMEKLH-HPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGK---
 .  |..| | .....  .|. |.   | |.|.| |..|.  ..|   .|.. .|    ||.|..|... .| .||.|.|||  ||||| ....|.    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTS---NTCVKVGDFGFSTV-SKK-GEMLNTFCGSPPYAAPELFR----DE-HYIGIYVDIWAL
.|| | . ....||.||.|.|. .||||||| ||. |..   .  .|. ||||.   . . .....|||..  |.|||. .    .. |  .  .|.| |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGH--DKACDWWSL

GVLLYFMVTGTMPFRA---ETVAKLKKSILEGT--YSVP--PHVSEPCHRLIRGVLQQIPTERYG-----IDCIMNDEWM
|||.| | ||  ||..   .. ... | |..|.   . |  . .|...  |||. |.  |  |.|     .. | ...|.
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase NIM1.AA Pkinase_Tyr 74-216 30 4.4e-23 78.8 Pfam 1-156 (270) Show / Hide 
Range on Protein: 74-216
Range on HMM: 1-156/270
Sequence Identity: 30% (48 aa)

YRIRGEIGSGNFSQVKLGIHS----LTKEKVAIKILDKTKLDQKT--QRLLSREISSMEKL-HHPNIIRLYEVVE-TLSK--LHLVMEYAGGGELFGKIS
 ..  ..|.|.| .|..|.       || .||.|.| | . ...   .. . ||.. | .| |||||.||| |.        . .||||. .| |     
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----EGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFG
.    ...|. ..   .  || ..  . .....||||| | |.  |.| .||..|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase NIM1.AA TyrKc 74-324 22 1.1e-16 46.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 74-324
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKL--HHPNIIRLYEVVETL-------SKLHLVMEYAGGGELFGKI-S
 .   ..|.|.| .| .|. .   ..||.| | . .     .. . ||.. | ||  |||||.||| |. .          | .||||. .| |   . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKG-------EMLNT-F--CGS--PPYA--APELFRDEHYIG
...||. ..   .  || .   . |....||||| | |. ...| .||..||| |   . .       ..  .    .|    |.   ||| ...  .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-T

IYVDIWALGVLLYFMVTGTMPFRAE------TVAKLKKSILEGTYSVPPHV---------SEPCHRLIRGVLQQIPTERYGIDCIMNDEW
.  |.|. ||... . |  ..   .      . . . . . .| .  .|.          ..  .....   .  | .|     |  ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
UBA_CAMKL NIM1.AA UBA_CAMKL 354-391 19 2.2e-05 17.69 In-house 1-41 (41) Show / Hide 
Range on Protein: 354-391
Range on HMM: 1-41/41
Sequence Identity: 19% (8 aa)

ENEVKSTLEHL--GITEEHIRNNQGRDAR-SSITGVYRIIL
. |.   ....  |...|.|..    . .   ||. |...|
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL