Gene NDR1 (Human)

NDR1

Species: Human
Alias: STK38, NDR, NDR1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards ,
Annotation: Consensus chromosomal location: 6p21.1-p21.3,

Classification

Group: AGC
Family: NDR
Subfamily: NDR

Sequence

Name Sequence Type Origin Length Description Download
NDR1.NA RNA Sugen Kinome 3593 None Fasta, JSON
NDR1.AA Protein Sugen Kinome 465 None Fasta, JSON
NDR1.kin_dom Protein Kinase Domain Sugen Kinome 294 None Fasta, JSON

Protein domain

Protein domains of NDR1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NDR1.AA NDR 89-382 54 1.6e-237 741.24 In-house 1-350 (350) Show / Hide 
Range on Protein: 89-382
Range on HMM: 1-350/350
Sequence Identity: 54% (190 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEAD--SLWVVKMFYSFQDKLNLYLIMEFLPGGDMMT---LLMKKDT
||..|.||.||||||.||.||||||.|||||.||..|..|.||.|.||||||..|||  . ||||..|||||| .|||.||..|||||||   ||||.|.
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTG---------------------LKKAHRTEFYRNLNHSLPSDFT----
.||....|||||.|.||.|.|..|.|||||||||.|.|..||.||.|||||||                     ... |....|.|...  |.||     
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

FQNMNSKR-----------------KAETWKRNRRQLAFSTVGTPDYIAPEVFMQ-TGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKET
 ..||.|.                 ....||.|||.||.||||||||.|||||.| ||||..|||||||.||||||.|||||||.|||||..|.||||.|
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

L-----TFPPEVPISEKAKDLILRFCC-EWEHRIGA--PGVEEIKSNSFF
.     .||||...|..|.||| |.|| ...||.|.   ||.|||| .||
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase NDR1.AA AGC 89-382 33 1.3e-188 493.02 In-house 1-395 (395) Show / Hide 
Range on Protein: 89-382
Range on HMM: 1-395/395
Sequence Identity: 33% (136 aa)

FESLKVIGRGAFGEVRLVQKK------DTGHVYAMKILRKAD--------MLEKEQVGH-------IRAERDILVEAD----------SLWVVK-MFYSF
|| |||||.|.||.|.||.||      |||..||||.|.|..        |.|. .. |       ...||.||....          . ..|| ..|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDKLN--LYLIMEFLP---------GG-DMMTLLM---KKDTLTEEETQFYIAE-------TVLAIDSIHQ-LGFIHRD-IKPDNLLLDSKGHVKLSDFG
||| .  ||..||..|         || .... |.   |. ...||...||.||       .|||....|. .|.|||| .||.|.|||..||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCTG----------------LKKAHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNR-----------RQLAFSTVG--TPDYIAPEVFMQTGYNKLC
||.                 ... |.... . ..     ...  . |. .....|.||.           |... . .|  ||.|.|||..    |.| |
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS-----NMD--T-NK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKAC

DWWS--LGVIMYEMLIGYPPFCSETPQ----------ETYKKVM------NWKETL------TFPPEVPISEKAKDLILRFCC-EWEHRIGA-P------
||||  ||..|||||.|||||....||          |...|.|      |||...      .||... .|. ||||| ...| . |.|.|. .      
DWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDK

GVEEIKSNSFF
|.||||.  .|
GAEEIKNHPWF
Kinase NDR1.AA DMPK 89-234 53 5e-114 283.15 In-house 1-147 (270) Show / Hide 
Range on Protein: 89-234
Range on HMM: 1-147/270
Sequence Identity: 53% (78 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKD-TLTEE
|| |||||||.|||| .|. | |. |||||.. |..|| ....   . ||||.| ..| |... .| |||. .||..||. ||||. ||. . .  . |.
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

ETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLC
 ..||.|| ||||.||||.|..|||||||| |||. ||.|| ||| |
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC
Kinase NDR1.AA RSK 92-382 36 6.4e-100 338.26 In-house 1-278 (278) Show / Hide 
Range on Protein: 92-382
Range on HMM: 1-278/278
Sequence Identity: 36% (114 aa)

LKVIGRGAFGEVRLVQKK---DTGHVYAMKILRKADMLEKEQ-VGHIRAERDILVEAD-SLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDT---
||| |.|..|.| |..|.   |||..||||.|.|| .  ..  . | ..||.|| .   .  .|. .|.||... ||||||...||.. | | |. .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDS---KGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNR-RQLA
..|.| .||.|| |||.. .||.|.||||.||.| |.|.    ||.||.|||.|  .                                   |..  |..
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----------------------------------RCDHNQWT

FSTVGTPDYIAPEVFM----QTGYNKLCDWWSLGVIMYEMLIGYPPFCS---ETPQETYKKVMNWKETLTFPPEVPISEKAKDLILR-FCCEWEHRIG--
 . ..| .|.|||. .    | |..| ||||||||.||||| |.||| .   ....|. |.... | .||.|    .|. ||||| . .. . . |.|  
MTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCG

APGVEEIKSNSFF
  ..||||....|
PQDAEEIKQHPWF
Kinase NDR1.AA S_TKc 89-382 31 7.4e-99 335.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 89-382
Range on HMM: 1-231/231
Sequence Identity: 31% (98 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPG--GDMMTLLMKKDT---
.| |..||.||||.|.....|.||...|.||..           ||| |..|| . .  ..||....|||  .||..||...|  ||..... |. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAF
   ..| ...||......|.. .|..|.||||.||.|.|||.  |.|..||||.. |                                           
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------T

STVGTPDYIAPEVFMQTGYNK-LCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCC-EWEHRIGAPGVEE---
. .|||.|.||||.   ||.|  |||||.|.|.|||| |||||.  ..|...||..              |. |||.| . .. . |.|..|  . .   
TFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

-IKSNSFF
 ||.  .|
DIKCHPWF
Kinase NDR1.AA AktR 89-382 36 2.3e-89 303.18 In-house 1-268 (268) Show / Hide 
Range on Protein: 89-382
Range on HMM: 1-268/268
Sequence Identity: 36% (109 aa)

FESLKVIGRGAFGEVRLVQKK-DTGHVYAMKILRKADMLEKEQVGHIRAERDILV-EADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTE
|. .|..|.||||.| ||||| |.. .||||...| .. |..|  |.. ||.|.  ...    ||..|.||.| .|..|||. |||.. . | || ...|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EETQFYIAETVLAIDSIHQL-GFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGT
|...||.|. .||..  ||    | ||.||.|.|||. ||||..||||                                      .. ....| | .||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK---------------------------------LQFMMHYDEKAYSFCGT

PDYIAPEVFMQ-TGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILR--FCCEWEHRIG--APGVEEIKSNS
| |.|||. ..  |.|| .|||..|.  |||..|.||| ..  .. ..|  .    . ||. ...|...|||| |  .|   ..|.|  ..| |||||  
PEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHP

FF
.|
WF
Kinase NDR1.AA MAST 89-233 46 1.3e-77 236.48 In-house 1-148 (337) Show / Hide 
Range on Protein: 89-233
Range on HMM: 1-148/337
Sequence Identity: 46% (69 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQD--KLNLYLIMEFLPGGDMMTLLMKKD-TLT
|| .|.|..||.| | ||..|.|.  .|||.... |.. | || ....||.||....  .|||||||||   |  |...||.. |||  .||     .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGL
|.....|||||||... .|  | .|||.||||.|.||.||.|| ||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGL
Kinase NDR1.AA MAST 89-233 48 5e-76 244.5 In-house 1-145 (334) Show / Hide 
Range on Protein: 89-233
Range on HMM: 1-145/334
Sequence Identity: 48% (70 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEE
||  |.|..||.| | || .|.|.  .|||...|.||. | .| . ..||.|| .... .||||||||| | .|...||.. |||  .||    .. |. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

TQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGL
...|||||||... .|. | .|||.||||.|.||.||.|| ||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGL
Kinase NDR1.AA Akt 89-234 44 7.3e-71 225.73 In-house 1-148 (264) Show / Hide 
Range on Protein: 89-234
Range on HMM: 1-148/264
Sequence Identity: 44% (66 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVY-AMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEE
|. |||.|.|.|| | ||.||||. .| |||.|.|   ..| || |. .|| ||.  ..  .|.. ||||.. .||..|.. .||.  ..| .| . .|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

ETQFYIAETVLAIDSIHQLGFIHRD-IKPDNLLLDSKGHVKLSDFGLC
.. ||.|| .|||.  |. . | ||  || |.|.|..||..| |||||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC
Kinase NDR1.AA GEK 89-239 55 2.6e-70 235.14 In-house 1-152 (269) Show / Hide 
Range on Protein: 89-239
Range on HMM: 1-152/269
Sequence Identity: 55% (85 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMK-KDTLTEE
|| ||||||||||||  |. |.|..||||||| | .|| .  .   | |||.||. |. |. .. | |||  .|||.|..  |||..||| | .| | |.
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

ETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKK
  .||||| |.||||.|||...||||||||.||| .||..| ||| |  ..|
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSCLRMNK
Kinase NDR1.AA ROCK 89-234 51 4.1e-64 217.21 In-house 1-145 (263) Show / Hide 
Range on Protein: 89-234
Range on HMM: 1-145/263
Sequence Identity: 51% (75 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEE
|. .|||||||||||.|| .| . .|||||.| | .|. .        ||||.  | | |.|...| |||.  ||..|...||||.. |. . | . |  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNYD-VPEKW

TQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLC
..|| .| |||.|.|| .||||||.||||.|||..||.|| ||| |
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTC
Kinase NDR1.AA DMPK 283-382 48 4.3e-61 149.27 In-house 162-270 (270) Show / Hide 
Range on Protein: 283-382
Range on HMM: 162-270/270
Sequence Identity: 48% (53 aa)

VGTPDYIAPEVF--MQTG----YNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNW-KETLTFPPEVP--ISEKAKDLILRFCCEWEHRIGAPGV
|||||||.|||   | ..    | . |||||.||.||||| |  ||  ..  ||| | ||  |. | ||....  .||.||||| .. |. |.|.|  |.
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

EEIKSNSFF
|..|   ||
EDFKCHPFF
Kinase NDR1.AA Pkinase 89-234 30 1.6e-48 172.31 Pfam 1-159 (293) Show / Hide 
Range on Protein: 89-234
Range on HMM: 1-159/293
Sequence Identity: 30% (49 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIR-AERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGG----DMMTLLM--KK
.. ...||.|.||.|.. ..|.||...|.||..| .  ..... |.| .|  |. . ..  .|.....|.|| ..|..||...||    | .....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DTL--TEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHV----KLSDFGLC
 ..  .|.| .||. ... ... .|. |.||||.||.|.|.|..||.    |..||||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase NDR1.AA MAST 283-382 43 3.4e-43 129.38 In-house 229-337 (337) Show / Hide 
Range on Protein: 283-382
Range on HMM: 229-337/337
Sequence Identity: 43% (47 aa)

VGTPDYIAPEVFMQTG-YNKLCDWWSLGVIMYEMLIGYPPFCSETPQE-TYKKVMNWKETLTFPPE------VPISEKAKDLILRF-CCEWEHRIGAPGV
.||||||||||   .| |.|  ||||.|.|||| |.|.|||  .||.| .  .. | .. . .|.|       ..|. |.||| ..       |.|| |.
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

EEIKSNSFF
.|||.  ||
DEIKQHPFF
Kinase NDR1.AA MAST 283-382 40 8e-40 125.84 In-house 225-334 (334) Show / Hide 
Range on Protein: 283-382
Range on HMM: 225-334/334
Sequence Identity: 40% (44 aa)

VGTPDYIAPEVFMQTG-YNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWK-ETLTFPPE------VPISEKAKDLILRF-CCEWEHRIGAP-G
.||||||||||  ..| ..|  ||||.|.|||| |.|.|||. .||.|.. .. | .     .|..        .|. |.||| ..  .  . |.||  |
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

VEEIKSNSFF
..|.|.  ||
ADEVKQHPFF
Kinase NDR1.AA ROCK 283-382 50 9.5e-38 125.96 In-house 160-263 (263) Show / Hide 
Range on Protein: 283-382
Range on HMM: 160-263/263
Sequence Identity: 50% (52 aa)

VGTPDYIAPEVFMQTG----YNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKS
|||||||.|||    |    | . ||||| || .||||.|  ||  ..   || |.|. |. |.||..| ||..||||| .|  . |.|.|  ||..|| 
VGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQ

NSFF
  ||
HKFF
Kinase NDR1.AA GEK 283-382 50 2.4e-37 122.66 In-house 162-269 (269) Show / Hide 
Range on Protein: 283-382
Range on HMM: 162-269/269
Sequence Identity: 50% (54 aa)

VGTPDYIAPEVF--MQTG---YNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVP---ISEKAKDLILRFCCEWEHRIGAPGVE
|||||||.||.   |. |   | . ||||||||.||||| |  || .|   ||| |.||.|. . ||...    .||.||||| .  |. |||.|  |..
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ

EIKSNSFF
. |   ||
DFKKHPFF
Kinase NDR1.AA Akt 284-382 38 1.4e-27 85.21 In-house 164-264 (264) Show / Hide 
Range on Protein: 284-382
Range on HMM: 164-264/264
Sequence Identity: 38% (40 aa)

GTPDYIAPEVFMQTGYNKLCDWWS-LGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCE--WEHRIG-APG-VEEIKS
||| |.|||.  ..|. | .|||. ||..||||. | ||| ..  .. .|| .|  . . ||.   || ..|||| . ...   ..| | .|. ..|||.
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKN--QPVKFPDKDWISPECKDLISG-LLNKDPKKRLGGGPNDAQEIKR

NSFF
  .|
HPWF
Kinase NDR1.AA Pkinase 283-359 29 1.1e-18 67.15 Pfam 172-272 (293) Show / Hide 
Range on Protein: 283-359
Range on HMM: 172-272/293
Sequence Identity: 29% (30 aa)

VGTPDYIAPEVFM-QTGYNKLCDWWSLGVIMYEMLIGYPPFCSE------TPQETYKKVMNWKETLTFPPEVPIS-----------------EKAKDLIL
.|||.|.|||| . ...| . .|.||.|.|.|||| |.|||...      .... ....|  .    .| . .||                 | .||.| 
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

R
.
W
Kinase NDR1.AA Pkinase_C 400-449 24 3.6e-11 42.59 Pfam 1-46 (46) Show / Hide 
Range on Protein: 400-449
Range on HMM: 1-46/46
Sequence Identity: 24% (12 aa)

EIKSIDDTSNFDEFPESDILKPTVATSNHPETDYKNKDWVFINYTYKRFE
..||..||||||.. ..   . |.   . ..   ..... |...||....
QVKSPTDTSNFDPEFTDEPPMDTP---PDWR-MSSGDQEPFRGFTYVNPD
Kinase NDR1.AA TyrKc 89-381 20 1.9e-10 -53.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 89-381
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEA--DSLWVVKMFYSFQDK-------LNLYLIMEFLPGGDMMTLLM
 . .|..|.||||||.. . |      | | |..        .  .. |  |. .   .   .|...    ..         |...||. |.||    | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKDT-LTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKA-HRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQ
|.   |. ..   .        . .|. ..||||.   | |......|| |||||.  ..   ..                    ... .  . ..... 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG------------------ESKDYYRKKEHKGGKT

-LAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEML-IGYPPFCS-----ETPQETYKKVMNWKETLTFPPE------VPISEKAKDLILRFCCE-
 |           |||...   ..   | || || |.|..  | .|         ..|| ...|..  . .  ||.      |  ...  ..... . | 
MLPIR------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ-GYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHED

WEHRIGAPGVEEIKSNSF
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PEDR---PTFSEI-HECF
Kinase NDR1.AA S_TK_X 383-447 27 2.8e-05 22.0 SMART 1-79 (79) Show / Hide 
Range on Protein: 383-447
Range on HMM: 1-79/79
Sequence Identity: 27% (22 aa)

EGVDWEHIR----ERPAAISIEIK----SIDDTSNFD-EFPE-----SDILKPTVATSNHP--ETDYKNKDWVFINYTYKR
 |.||....    | .. .  .||    |  |||||| ||.|     ... .| ..... .  ||     .  |...||..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETE--IPPDPFRGFTYVF
Kinase NDR1.AA Pkinase_Tyr 161-234 29 3.2e-05 18.31 Pfam 81-158 (270) Show / Hide 
Range on Protein: 161-234
Range on HMM: 81-158/270
Sequence Identity: 29% (23 aa)

NLYLIMEFLPGGDMMTLLMK----KDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLC
..|..||. |.||. . | |    |. || ..   . ..   . .  .. ..||||.   | |......|| .||||.
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase NDR1.AA Pkinase_Tyr 89-105 47 0.022417 8.67 Pfam 1-17 (270) Show / Hide 
Range on Protein: 89-105
Range on HMM: 1-17/270
Sequence Identity: 47% (8 aa)

FESLKVIGRGAFGEVRL
 . .|..|.||||||..
ITFGKKLGEGAFGEVYK
Kinase NDR1.AA Pkinase_Tyr 290-336 28 0.083263 6.74 Pfam 182-231 (270) Show / Hide 
Range on Protein: 290-336
Range on HMM: 182-231/270
Sequence Identity: 28% (14 aa)

APEVFMQTGYNKLCDWWSLGVIMYEMLI-GYPP-FCSETPQETYKKV-MN
|||...   ..   | || || |.|..  |  | .   ...| |...  .
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED