Gene MST4 (Human)

MST4

Species: Human
Alias: MST4, MASK, LOC51765, RP6-213H19.1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: Xq26,

Classification

Group: STE
Family: STE20
Subfamily: YSK

Sequence

Name Sequence Type Origin Length Description Download
MST4.NA RNA Sugen Kinome 3352 None Fasta, JSON
MST4.AA Protein Sugen Kinome 416 None Fasta, JSON
MST4.kin_dom Protein Kinase Domain Sugen Kinome 251 None Fasta, JSON

Protein domain

Protein domains of MST4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MST4.AA YSK 24-274 78 5.6e-239 727.79 In-house 1-257 (257) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-257/257
Sequence Identity: 78% (202 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA---GPFDEFQ
|||.|.||.||||||.||||||||.||||||||||.||||||||||||..||||||.|.|||||||||..||||||||.||||.|||...   |.||| .
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQ--SAYDSKADIWSLGITAIELAKGEPP
||..|.||||||||||||.|||||||||||||||.|||||.|||||||.||||||||||||||.|||||||.|  |.||.|||||||||||.|.||||||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

NSDMHPMRVLFLIPKNNPPTLVG-DFTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
..|.|||||.|||||||||.| | ...|.||||...||||||..||.||||||||||
YCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase MST4.AA STE20 24-274 52 7.50000000001e-169 567.25 In-house 1-288 (288) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-288/288
Sequence Identity: 52% (151 aa)

FTKLERIGKGSFGEVFKGIDNRTQQV----VAIKIIDLEEAE---DEIEDIQQEITVLSQCDSSYVTKYYGSYLKG----SKLWIIMEYLGGGSALDLLR
...||.||.||.|.|.|.....|...    ||||...||...   ||.||||.|| ...||.. ...||||||||.    ..|||.|||.||||..|...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

-----AG-----PFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD----TQI-KRNTFVGTPFWMAPEVIQQ----
      .     |..| |||....|.|.|||||||...|||||||.|.||.|.|.||||||||..|||.    |.  |||||||||.||||||||.    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-SAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIP--KNNPPTLVG----DFTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
 . ||.|.|||||||||||.|.||||..||||||..|.||  .| |||| .     ....|..|.| ||.|||..||||..||||.||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MST4.AA MST 24-274 52 1.4e-144 462.55 In-house 1-254 (254) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-254/254
Sequence Identity: 52% (135 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYL--KGSKLWIIMEYLGGGSALDLLRAG--PFDEF
|...|..| ||.| |.| |.  | ..||||..  .|    ...|  ||. ..||.| |. ||||||.  | . .||.||| |.||..|. ..   .. | 
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNE---DLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQ

QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN
|||. |.  |.||.|||. |||||||||.| ||.. |  |||||||.||||||. ||||..|||.||||||||.. ||.|||||||||||||.| |.|| 
QIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPY

SDMHPMRVLFLIPKNNPPTLV--GDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
|| ||||..|.||.. |||.     .   |  |.  || |.|. |.||..||.| ||
SDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase MST4.AA STE 24-274 38 1.4e-141 476.61 In-house 1-359 (359) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-359/359
Sequence Identity: 38% (140 aa)

FTKLERIGKGSFGEVFKGIDN------RTQQV---------VAIKIIDLEEAE----------------DEIEDIQQEITVLSQCD--SSYVTKYYGSYL
....|.||||.||.|.|....      .|..|         .|||...||. .                .|...|..|| ....|.  . .. ||||.|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KG-------SKLWIIMEYLGGGSALDLLRA---------------GPFDEFQIATMLKEILKG-LDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAG
|.       ..|||.|||..|||. |...                ..|.| |||.....|||| |.|||| ..||||||.||.||     |||.||||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTD---------------TQI-KRNTFVGTPFWMAPEVIQQ------SAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKN-----------
||||               |.  ||||||||| |||||||||      . || |.||||||.|.||.| |.|| .||||||..|.||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----NPPTLVG-------------------DFTKSFKEFIDACLNKDPSFRPTAKELLK--HKFI
    .||.|                      ....||.||. ||.|||. ||||..|||  |.||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MST4.AA FRAY 24-274 45 9.69999999999e-110 342.09 In-house 1-277 (277) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-277/277
Sequence Identity: 45% (125 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAE-DEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLR----AGP---
.   | ||.|  . |.| .    |  .|||.|.||  .   ....  || . .||    | .|. |..    ||..| ||..|| ||...    .|    
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

---FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD-----TQIKRNTFVGTPFWMAPEVIQQSA-YDSKADIWSLG
   |||  ||| |||.||||.|.|.  .||||||| |.|. | | . .||||| . | .     ..  | |||||| ||||||. |   || ||||||.|
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG

ITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGD---------FTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
|||||||.| .|  .  || || |.  |.||.| .|         . .|||. |. || |||| |||| ||||||| 
ITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase MST4.AA PAKA 24-274 43 1.5e-104 353.67 In-house 1-260 (260) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-260/260
Sequence Identity: 43% (113 aa)

FTKLERIGKGSFGEVFKGIDNRTQQV--VAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGP------
....| ||.|. |||..... .|.|   |||| ..... .. .| |  || |. .|    . .|. |||  ..||..|||..||.  |.. .        
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKG
.|| |||  ..|.|.||...||.. ||||||  |.||  .|.||..||| . |||. | |||| |||| |||||||..  || | ||||||| |||.. |
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

EPPNSDMHPMRVLFLIPKN-NPPTLVGD-FTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
|||  .. | | ..|| .|  |. .  | ....|..| |.||..|.  |..|.|||.| |.
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase MST4.AA KHS 24-274 48 1.2e-102 346.06 In-house 1-258 (258) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-258/258
Sequence Identity: 48% (126 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA-GPFDEFQIA
.  | |.| | .|.|.|  | ......|.|.| . |..|... |||||... .|  . .  |.||||.  ||||.||| ||||  |. .. ||  | |||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKM-EPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIA

TMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPN
 . .|.|.||.||||..|.||||| ||.||..|||||||||||..|.| |  ||  |.|||.||||||    ..  |.   |||..||||||||   || 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

SDMHPMRVLFLIPKNN--PPTLV--GDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
 |.||||.|||. | |  ||.|     ....| .|.  .| |.|  ||||. ||.|.|.
FDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase MST4.AA PAKL 24-274 45 1.1e-101 344.18 In-house 1-256 (256) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-256/256
Sequence Identity: 45% (116 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKG-SKLWIIMEYLGGGSALDLLR--AGPFDEFQ
|   |  | ||.| |.|.|   |  . ||| | . |.  ||.||. || .|  | . ..  |.||   . ...|| |.|   ||  |..      ..| |
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESN-EIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQ

IATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQI-KRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN
|.  |.  |||| ||||   |||||||||.||.| ..||.|||||  || |.     |  .|||.|||||.| .  |..|.|||||||||||.| |.||.
ISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPH

SDMHPMRVLFLIPKNNPPTLVG--DFTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
.|| ||| .  ||   |||.    .. . |  |.. |. |||  |. . .|| | ||
YDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase MST4.AA S_TKc 24-274 33 6.2e-99 335.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-231/231
Sequence Identity: 33% (89 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGG--GSALDLLRAGP------
...|. ||||.||.|.|.....|...||||||.        |.|..|| .|.. .  .. |.|...   ..|...|||..|  |. .|...  .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDS-KADIWSLGITAIELA
 |.| ... ....|...|.|.|| . ||||.| .|.||.|   .|..|||.| ||       .||.|||..|||||.    |.  |.|.||.|.. .|..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

KGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLK-------HKFI
 |.|| .  ...... .|            ....|.||. ||.|||. |||| |.|.       | ..
CGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MST4.AA Pkinase 24-274 29 7.6e-92 316.23 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQ---EITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGG----SALDLLR---A
......||.||||.|.|...  |...||.|||........ . .     || ..  ... .. ..|...  .......|||..||    .  |...    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPF--DEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDV----KLADFGVAGQL-TDTQIKRNTFVGTPFWMAPEVIQ-QSAYDSKADIWSL
|.|  .| ..  ....||.||.|.||.. ||||.| .|.|....|..    |..|||.| |. .  .   .||.|||..||||||. .. |..|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITAIELAKGEPPNSDM----HPMRVLFLIPKNNPPTLVGDFT-----------------------KSFKEFIDACLNKDPSFRPTAKELLKHKFI
|.. .|.. |.|| ..     . .. ...| .. .| |  |.                        ...|.||. ||.|||. ||||...|.|...
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MST4.AA MSN 24-274 46 2.1e-91 302.05 In-house 1-265 (265) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-265/265
Sequence Identity: 46% (125 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQ-CDSSYVTKYYGSYLKGS------KLWIIMEYLGGGSALDLLRA---
|   | .|.| .|.|.||.  .| |..|||..|..|  || |.|.||| .| .      .  ||| ..| |      .||..||. | ||  ||..    
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE--DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKG

GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQ-----QSAYDSKADIWSLGIT
    |  || . .|||.|| .||..| ||||||  |||| .. .||| ||||. ||  |  .||||.|||.|||||||.     . .||...|.||.|||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL-VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
|||.| |.||  |||||| |||||.| ||.|    ..| |..|.. || |. ..||.....||| ||
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase MST4.AA Ste20-DD1 24-274 42 5.8e-85 288.58 In-house 1-268 (268) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-268/268
Sequence Identity: 42% (115 aa)

FTKLERIGKGSFGEVFKG-------IDNRTQQVVAIKIIDLEE-AEDEIEDIQQEITVLSQC-DSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLR--
|  .| || |||| |          ..    .|.|.| . ..     |      ||..|    |  |. || | |.| . | |.|||  ||| || .   
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMC

AGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQ----SAYDSKADIWSLGIT
     | |||  .  | ||| |||| . .|||||| |||. . |  |||||||   .  .  | || .| |.||.||.|        ||.||||||||||
SKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGIT

AIELAKGEPPNSDMHPMRVLFLIPKNNPPTLV--GDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
|||.|   ||  .. | || | ||   ||||   ..    |  ||  |||..|  || | .|| | ||
AIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase MST4.AA Pkinase_Tyr 24-274 30 4.8e-41 139.63 Pfam 1-270 (270) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-270/270
Sequence Identity: 30% (83 aa)

FTKLERIGKGSFGEVFKGIDN----RTQQVVAIKIIDLEEAEDE---IEDIQQEITVLSQC-DSSYVTKYYGSYL-KGSK--LWIIMEYLGGGSALDLLR
 |... .|.|.||||.||. .     |.. ||.|..  | | .|   .||  .|. ...|  .   . ..||  . .|    ..|.|||  .|. || ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AG-----PFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQL--TDTQ-IKRNTFVGTPFWMAPEVIQQSAYDSKADIWS
.      |..  ..  |  .| ||..||.| . ||||. | |.|..|.. || .||| |  .  .|.   ||       .|||||.|. . . .| |.||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGITAIELAK-GEPP-NSDMHPMRVLFLI-PKNNPPTLVGDF--TKSFKEFIDACLNKDPSFRPTAKELLKHKFI
 |..  |.   || |   .| . .|. .|  ...   .      ..   . .  | ..||. ||| .|.  | ..
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase MST4.AA TyrKc 24-274 24 1.5e-33 118.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

FTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQC--DSSYVTKYYGSYLKG-------SKLWIIMEYLGGGSALDLLRAG
 |... .| | ||||.||. .   . ||.| .  .     .||. .|. ....   .   . . ||  ...         |.|.|||  .|. .| ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

P--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDT-------QIKRNTF-VGTP-----FWMAPEVIQQSAYDSK
   .   .   .   | .| .|||| . ||||. | |.|..|.. || .||| .  ..|        . .| .   |.       |||||.|. . . .|
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

ADIWSLGITAIELA-KGEPPNSD-----MHPMRVLFLIPKNNPPTLVGD--------FTKSFKEFIDACLNKDPSFRPTAKELLKHKFI
 |.|| |..  |.   |..| ..     | . .|. .. . . .    .         ..   . .  | . ||. ||| .|.  |...
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF