Gene MPSK1 (Human)
MPSK1
Sequence
Protein domains of MPSK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | MPSK1.AA | MPSK | 20-290 | 65 | 1.9e-227 | 761.86 | In-house | 1-281 (281) | Show / Hide |
Range on Protein: 20-290 Range on HMM: 1-281/281 Sequence Identity: 65% (184 aa) YLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAY-CLRERG-----AKHEAWLLLPFFKRGTLWNEIERL |.|.|.|||||||||||||.||||||||||||.||||||...|||||.||..|.||||.|||.. ||..|. .|||.||.||.||.||||....|. YYFMQRLGEGGFSYVDLVENLHDGHFYALKRIQCHEQQDQNQAQREAEMHCQFDHPNIIRLVDWGCLKGREDIVINTKHEIWLVLPYFKHGTLWDHLQRM KDKGNFLTEDQILWLLLGICRGLEAIH---AKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHC ||||...|||||.|..||.|.||.||| .|.|||||.|||||.|||..|||.|||||||.|||.|.|.|||..||||||.||...|||||||.||||| KDKGDCMTEDQIWWIFLGVCEGLKAIHEAMPKPYAHRDMKPTNICLGDDFQPVIMDLGSMNEACIQVKGQRQACALQDWAAERCSMVYRAPELFHVQSHC VIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQN-QLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQL |||||||.||||||||||.....||||..|.||||.||||| ...||...|.|....||...||.|||..||||...|.|. VIDERTDIWSLGCVLYAMCYFHSPYDMIYQRGDSVHLAVQNRNFNIPENSRYSQDMHQLISYMMRVDPMERPHIFWVLNQT |
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Kinase | MPSK1.AA | NAK | 20-290 | 37 | 1.9e-148 | 498.72 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 20-290 Range on HMM: 1-299/299 Sequence Identity: 37% (113 aa) YLFIQKLGEGGFSYVDLVE---------GLHDGHFYALKRILCH-EQQDREEAQREADMHRLFNHPNILRLVAY-CLRERG---AKHEAWLLLPFFKRGT | ....|.|||||||.||. ....|..|||||..|| ..|| ....||..|.....|.|..... . .. || ..|..||......|. YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS LWNEIERLK-DKGNFLTEDQILWLLLGICRGLEAIH----AKGYAHRDLKPTNILLGD---EGQPVLMDLGSMNQACIHVEGSRQALT---LQDWAAQRC ||..... . |||...|||.||......|.|..|.| .|...|||.|..||||.. .|...|.|.|||..|.|..|....|. .|||..... LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYT TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQN---QLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQL |..|||||.. ..|.|.|||..|.|.|||.||.|.|.. |.....|..||..||.|| ..|||...|.|.....| |.|.||.|||.|. .|.|| TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL |
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Kinase | MPSK1.AA | NAK-Unclassified | 20-292 | 21 | 1.7e-66 | 227.19 | In-house | 1-405 (405) | Show / Hide |
Range on Protein: 20-292 Range on HMM: 1-405/405 Sequence Identity: 21% (86 aa) YLFIQKLGEGGFSYVDLV---------E-----GLHDGHFYALKRILCHEQQDREEAQREADMHRLFN-HPNILRLVAYCLR--ERG-AKHEAWLLLPFF | . |.|||||.| || .. . |.|||..| ... ... || | ..|. |||| . . .. | .|... YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC KRGTLWNEIE-----RLKD-KGNFLTEDQILWLLLGICRGLEAIHAKGY----------------------------------------------AHRDL .||.| . .. ......| .| ...|.|. . |. .|||. SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI KPTNILLG----------------------------------------------------------DEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAA |. |.|. ..| ..|.|.|| .. | .| . ... |||| KIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIENRQEMQYLQDWIN QRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKG-DSVALAVQN---QLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLL . .| |||||.. . |.|||. |.|.||| || |.|. | .| | . ||.... . ..| ...|. | .| | .|| |||.| .| MHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQVL SQLEA .. NHICQ |
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Kinase | MPSK1.AA | S_TKc | 20-297 | 22 | 3.2e-45 | 157.48 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 20-297 Range on HMM: 1-231/231 Sequence Identity: 22% (64 aa) YLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKR--GTLWNEIERLKDKG | ...|.|.|.|. | .. ..|. .|.|.| | ..|| .... .|||| .| .. .. .. . . |.| |.. . .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHG NF--LTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDE- . ..| .. .. ||..|| .| .| |||||| |||| . . . | |. | . | |.|||.. . LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL------GYGKC RTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLS--QLEALQPPA . |.||.||.|| |. |. |.. ... .. . |. ...... ....|| .|| . .| .. .. | KCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | MPSK1.AA | Pkinase | 20-290 | 20 | 1.2e-39 | 141.29 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 20-290 Range on HMM: 1-293/293 Sequence Identity: 20% (66 aa) YLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQD--REEAQR--EADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRG----TLWNEIE | ...|.|.|.|. | . .|. .|.|.| ... . .... | |. ... .|||||.|| .. . | . .. ... | |. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLF---D RLK-DKGNFL--TEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQP----VLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELF ... .... . .|... .. |.|||| .|..| |||||| |||. ..|.. . | |. |. . .|. |.|||. YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYMAPEV- SVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGD----------SVALAVQNQLSIPQSPRHS-------------------SALRQLLNSMMTV .... .. . |.||.||.|| |..|. |. |. ... . .|. . . .| .......... .. -IRGGQYYGPKVDMWSCGCILYEMLCGR----PPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK DPHQRPHIPLLLSQ--L ||..|| .. .| . DPKKRPTAEQILQHPWF |
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Kinase | MPSK1.AA | TKL | 26-290 | 16 | 3.3e-33 | 116.66 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 26-290 Range on HMM: 1-364/364 Sequence Identity: 16% (61 aa) LGEGGFSYVDLVEGLHDG----------HFYALKRILCHE---------------------------QQDREEAQREADMHRLFNHPNILRLVAYCLRER .|.|||. | . | | |.. |. .. |.. .|. |.. ..||||.....||.... IGSGGFG--EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPP G--AKHE-------AWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHA--------KGYAHRDLKPTNILLGDEGQ---------- . . .. .. . ..|.|.. . .|.. . |.|.||.. |. .. .|||||. |||. . .. CGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN ----PVLMDLGSMNQACIHVEGSRQALTLQDWAA------------QRCTISYRAPELFS---VQSHCV----------IDERTDVWSLGCVLYAMMFGE . . |.| . . . .... | . |. |. . |||.. ...| .|..||.| | ||. .. .. ADWCCKICDFGLSRFMSQSGNMNDTMTTMME--SAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC GPY---DMVFQKGD-------SVALAVQNQLSIPQSPRH-------SSA---LRQLLNSMMTVDPHQRPHIPLLLSQL || .. ... ... .... || ... ... ...|. . ||..|| .|..| RPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | MPSK1.AA | Ciliate-E2 | 20-281 | 19 | 7.1e-30 | 99.73 | In-house | 1-353 (365) | Show / Hide |
Range on Protein: 20-281 Range on HMM: 1-353/365 Sequence Identity: 19% (72 aa) YLFIQKLGEGGFS-----YVDLVEGL------------------HDGHFYALKRILCHEQQDREEAQREADMHR----------------LFNHPNILRL | ||.|.|.|.|. |..| . .. .||.|.. .... |. .| .. | . |||||... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIM---KKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKM VAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFL-------TEDQILWLLLGICR---------------GLEAIHAKG-YAHRDLKPTNILLG . . . .. | . ... |.|. |. | | |. || .|. . |.. .|| .| |. |||.|| |||. YECFQEK--DDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF- DEGQPVLMDLGS------MNQACIHVEGSRQALTLQD------------------WAAQRCTISYRAPELFSVQS------HCVIDERTDVWSLGCVLYA . . |.| || ..| .. .. . .| | ||| .. .. . |. |.||||..|| ----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE MMFGEGPYDMVFQKGDSVALAVQN-QLSIP----------------QSPRHSSALRQLLNS----MMTVDPHQRP |.||. |. .. ....| .| .|.. |. .|| .|. MLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRI |
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Kinase | MPSK1.AA | STE | 20-293 | 19 | 6.8e-26 | 88.48 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 20-293 Range on HMM: 1-359/359 Sequence Identity: 19% (72 aa) YLFIQKLGEGGFS--YVDLVEG---LH----------DGHFYALKRILCHEQ-----------------QDREEAQREADMHRLFN--HPNILRLVAYCL . .|.|.|.|.| | . .| | ..| |.. .. ..... ..| .... .| |||| . ... WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF RE---RGAKHEAWLLLPFFKRGTLWNEIERLKDKGN----------FLTEDQILWLLLGICRG-LEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMN .| ....| |. . . |.| |.. . .|. .. |.|| . . |..| |. .| ... |||.|| |||| | | | KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG QACIHVEGSRQALTLQDWA---------AQRC-----TISYRAPELFSVQSHC---VIDERTDVWSLGCVLYAMMFGEGPY---DMV---FQKGDSV--- | .. .. | . .|.. | . ||| . .... |.. |.|||||.. | |. |. |.. .. QLTDSMANI-Q-S-----NNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQ ----ALAVQNQLSIPQSPRH--------------------SSALRQLLNSMMTVDPHQRPHIPLLLSQ-LEAL | ... .|. | | |. ... .| . ||..|| ||. . . QQFEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | MPSK1.AA | BIKE | 24-290 | 29 | 1.5e-24 | 84.85 | In-house | 5-267 (267) | Show / Hide |
Range on Protein: 24-290 Range on HMM: 5-267/267 Sequence Identity: 29% (80 aa) QKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREAD-MHRLFNHPNILRLVAYCLRERGAK-HEAWLLLPFFKRGTLWNEIERLKDKGNFLT ..| ||||. | || . |.| .|||| ..| . . || |. . | || | | | .| .. .. . | . . .| ..| EQLAEGGFAMVFLVRD-HKGNKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGVWECMILMEYCRH-QVVNMMNQRLQQGQYFT EDQILWLLLGICRGLEAIHAKGY--AHRDLKPTNILLGDEG--QPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTD |. .| .| .| ||||| |||| |.| || | || .. .| . |..|||||. | | . | EQEVLQIFCDVCEAVSRLHHCQTPIIHRDLKVENILLHDHGPPHYVLCDFGSATNKFLNPQ-KHGVNYVKDEIEKYTTMCYRAPEMIDLYSGKEITTKAD VWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQN-QLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQL .| ||| || . | |. | | ||... . .|| ... | ...| |. .|. .|| | |.. IWALGCMLYKLCFFCLPF------GES-QLAICDGNFTIPDNSKYSREMHCLIRYMLEPDMEKRPDI-YQVSHV |
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Kinase | MPSK1.AA | Ciliate-E2-Unclassified | 20-281 | 18 | 2.6e-24 | 81.22 | In-house | 1-341 (352) | Show / Hide |
Range on Protein: 20-281 Range on HMM: 1-341/352 Sequence Identity: 18% (67 aa) YLFIQKLGEGGFSYVDLVEGLHDGHFY-----ALKRILCH----EQQDREEAQREADMHRL------------------FNHPNILRLVAY--------- | .|...|.|||. | ... .. .| . | . .. ...| |. . . | .. ..||.|.... . YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI ------------CLRERGA---KHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQIL-----WLLLGICRGLEAIHAKG-YAHRDLKPTNILLGDEG-- ....|. | |.. . . ... .|| |.. .. |. ||| .| |. |||.|| |||. ..| VMEYCEGGDLWQYIKKRKKQKQK---------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKN -QPVLMDLGSMN------------QACIHVEGSRQALTLQDWAAQRC-TISYR----APELFSVQSHCVIDER----TDVWSLGCVLYAMMFGEGPYDMV .. . |.|. | ... . |. . ..| |..| |||.. | . |.. |.||||..||.|.||. |.. YYIKIIDFGISKKYQQNNNCDTNQQ-------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNY---DHSKAYKCDIWSLGVILYEMLFGYYPFYDN FQKG---------------DSVALAVQNQLSIPQSP------RHSSALRQLLN----SMMTVDPHQRP .. |.....| .| . | ..| .|. ..| .|. NCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI |
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Kinase | MPSK1.AA | CAMK | 25-283 | 15 | 2.6e-24 | 74.65 | In-house | 1-416 (425) | Show / Hide |
Range on Protein: 25-283 Range on HMM: 1-416/425 Sequence Identity: 15% (64 aa) KLGEGGFSYVDLVEGLHDG------------HFYALKRILCH----------------------------EQQDREEAQREADMHRL-------FNHPNI .||.|.|. | |.. ... . .| | | ...||.. .|| ..... .|||| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LRLVAYCL--------RERG-AKHE--------AWLLL---PFFKRGTLWNE-IERLKDKGNF--------------LTEDQILWLLLGICRGLEAIHAK ..| . .. . .. . . | | . ......|.. .||.. . || ... .| . IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH GYAHRDLKPTNILL-GDE----------------GQPVLMDLGSMNQACI---------HVEGSRQALT-------LQDWAAQRCTISYRA-PELFSVQS . .|||||| |||| .. .. . | | |. . .|. . . | . | .| | ||... .. NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG -----------HCVIDERTDVWSLGCVLYAMMFGEGPYD-----MVFQKGDSVA-----------LAVQNQLS-IPQSPRHSSA---------------- . ... .|.||.|..||.| |. |.. . .. . . . . . .| ..|. HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D---EWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH -----LRQLLNSMMTVDPHQRPHI ..|...|..||| .|. | FVSQECKDLIRKMLQVDPEKRMTI |
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Kinase | MPSK1.AA | TyrKc | 20-290 | 20 | 2.4e-12 | -23.02 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 20-290 Range on HMM: 1-280/280 Sequence Identity: 20% (62 aa) YLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLF--NHPNILRLVAYCLRE--RGAK---HEAWLLLPFFKRGTLWNEIER ...||||| | | . . | | . . ||. ||| . . . .||||.||...|. . . . .... . . | | .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDL---KDY LKDKGNFLTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIH------VEGSR-------QALTLQDWAAQR--CTIS |..... |. .. | . |..| | .| |.. |||| |.|.|... .. | .. . . . . | LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR YRAPELFSVQSHCVIDERTDVWSLGCVLY-AMMFGEGPYD-MVF--QKGDSVALAVQNQLSIPQSPR--------HSSALRQLLNSMMTVDPHQRPHIPL ||| . ... . .|||| | ... . .|. || |.. . . | |.. || | .... |. . ||..|| WMAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE LLSQL . ... IHECF |
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Kinase | MPSK1.AA | NEK | 20-77 | 30 | 4e-10 | 32.24 | In-house | 1-66 (286) | Show / Hide |
Range on Protein: 20-77 Range on HMM: 1-66/286 Sequence Identity: 30% (20 aa) YLFIQKLGEGGFSYVDLVEGLHDGHF-----YALKRILCHE--QQDREEAQ-READMHRLFNHPNI | |.|.|.| |. | .|. || |..|.| . ......|| |. . .|||| YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNI |
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Kinase | MPSK1.AA | NEK | 103-160 | 29 | 1e-09 | 30.76 | In-house | 90-156 (286) | Show / Hide |
Range on Protein: 103-160 Range on HMM: 90-156/286 Sequence Identity: 29% (20 aa) R-GTLWNE---IERLKDKGNFLTEDQILWLLLGICRGLEAIHAK-----GYAHRDLKPTNILLGDEG . |.| . |.. |.|| .. |.||.. . .| .| .| . |||.|| || | ... GGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNN |
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Kinase | MPSK1.AA | Pkinase_Tyr | 56-149 | 26 | 1.3e-05 | 19.58 | Pfam | 42-137 (270) | Show / Hide |
Range on Protein: 56-149 Range on HMM: 42-137/270 Sequence Identity: 26% (26 aa) QQD--REEAQREADMHRLF-NHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDK---GNFLTEDQILWLLLGICRGLEAIHAKGYAHRDL ... ||. ||| . . . .||||.||.. |..... . . .. ... . | | . |... .. || ..| . |..|.| ..|.. |||| HEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDL---LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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Kinase | MPSK1.AA | NEK | 213-226 | 64 | 2.6e-05 | 15.1 | In-house | 202-215 (286) | Show / Hide |
Range on Protein: 213-226 Range on HMM: 202-215/286 Sequence Identity: 64% (9 aa) DERTDVWSLGCVLY ... |.|||||||| NNKSDIWSLGCVLY |
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Kinase | MPSK1.AA | NEK | 262-292 | 32 | 0.001414 | 8.92 | In-house | 256-286 (286) | Show / Hide |
Range on Protein: 262-292 Range on HMM: 256-286/286 Sequence Identity: 32% (10 aa) SSALRQLLNSMMTVDPHQRPHIPLLLSQLEA |. |..|...| ..||.||| . .|.. SQDLQNLISQMLQKDPEQRPSCNQILEMPFI |