Gene LTK (Human)

LTK

Species: Human
Alias: LTK, TYK1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 15q14-q15,

Classification

Group: TK
Family: ALK

Sequence

Name Sequence Type Origin Length Description Download
LTK.NA RNA Sugen Kinome 3143 None Fasta, JSON
LTK.AA Protein Sugen Kinome 864 None Fasta, JSON
LTK.kin_dom Protein Kinase Domain Sugen Kinome 270 None Fasta, JSON

Protein domain

Protein domains of LTK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LTK.AA ALK 510-779 73 2.5e-230 771.47 In-house 1-273 (273) Show / Hide 
Range on Protein: 510-779
Range on HMM: 1-273/273
Sequence Identity: 73% (201 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHL
.||.||||||||||||.|.....||||.|.|||.|||||.||.|||.||.|||||..||.|||.|||.|......|..|.||.|.|||||||||..||| 
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLRECRPHP

G--QPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDI-YRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDS
.  |||.|.|.||||...|.||||||||||||||||||||||||.|.||.|||||.|||||||| |||.|||.|.||..||||||||||..||||||||.
ESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGGRAMMPVKWMPPEAFMDGIFTSKTDV

WSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQY
||||||.||||||||||||||.||||..||. ||||||||.||.||||||||||||.||.||.|..|||..||
WSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRNCPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase LTK.AA Pkinase_Tyr 510-777 44 2.2e-136 462.54 Pfam 1-270 (270) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-270/270
Sequence Identity: 44% (124 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQD--ELDFLMEALIISKF-RHQNIVRCVGLSL-RATP--RLILLELMSGGDMKSFLR
.|... ||.|||||||.|   |  .|.  ..||.|.|.| .....    ||. || | ... .|.||||..|  . .  |   .| .|.| .||....||
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

HSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYY-RRGDRALLPVKWMPPEAFLEGIFTS
  |    .. || | |||| ...||.|. |||....||||.||||||...   ..|.||.|||.|||||  .|| | .. . ||.|||.||.. .|.||.
KHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTT

KTDSWSFGVLLWEIFSLGYMP-YPGRTNQEVLDFV-VGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERL
|.| ||||||.||||..| .| ||| .|.||....   |.||..|..|| ..|..|.|||...|| ||.|. |.|.|
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase LTK.AA TyrKc 510-777 40 1.9e-126 427.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-280/280
Sequence Identity: 40% (123 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKF--RHQNIVRCVGLSLRA-------TPRLILLELMSGGDMKS
.||.. ||.|||||||.|  .        .|||.|.| | .    . ||. || | .|.  .|.||||..|  .          | .|..|.|..|| |.
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRA-------SYYRR----GDRALLPVKW
.|| .||.      | |.|||. . .||.|. ||.....||||.||||||..  .   ..||.|||..||||         .|||     | ...||..|
YLRKHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPG-----RTNQEVLDFVVGGGRMDPPRG--------CPGPVYRIMTQCWQHEPELRPSFASILER
|.||.. .|.||.|.| |||||..||||..| .||||      .||||. .|  |.||..|          ||  .|.||.|||...|| ||.|. | |.
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase LTK.AA TK 510-777 24 1e-116 393.03 In-house 1-486 (486) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-486/486
Sequence Identity: 24% (120 aa)

VTLLRALGHGAFG---EVYEGLVIGLP--------------------GDSSPLQVAIKTLPELCSPQDEL-------------DFLMEALIISKFR----
.||.. ||.|.||   |||.|...|..                    ..  . .||.|.| | .. ..|              |||.||.......    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HQNIVRCVGLSLRA------------TPRLILLELMSGGD----MKSFLRHSRPHLGQ-----------------------------------------
 |.||||..| ...              | .|..|.|..||     ...|| .||.  .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------PSPLVMRDLLQ-------------------LAQDIAQGCHYLEEN------HFIHRDIAARNCLLSCAGP--------SRVAKIGDFG----
        |.|| ..||||                    ...||.|. ||...      .|.|||.||||||..  ..         .|.||.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----MARDIYRASYYRRGD------------------------RALLPVKWMPPEAFLEGI---------FTSKTDSWSFGVLLWEIFSLGYMPYPG-RT
    .|||||. ..|.| .                        .. ||..||.||......         ||.|.| ||||||.||||..| .||.|  .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------QEVLDFVVGG--------------GRMDPPRGCP--------------GPVYRIMTQCWQHEPELRPSFASILERL
|         |||..... |               || .| .||                .|..|.|||...|| ||.|. ..|.|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LTK.AA Sev 510-777 46 1.2e-109 366.47 In-house 1-277 (277) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-277/277
Sequence Identity: 46% (128 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSS-PLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPH
 .|.| || ||||||||| ..   | .. . .||||||      |.   || || . |||.| |||  .|  |   |  | .|.| |||  ..||  |  
LKLRRFLGSGAFGEVYEGQAKDIDGVGEEEQRVAIKTLRKGSTDQEKQEFLKEAHLMSKFKHPNIVCQMGVCLDNEPQYIIMEHMEGGDLLCYLRAARMT

LGQPSP----LVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSC-AGPS---RVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIF
  | .     |   ||. .  ||. || |||. ||.||| |.|||| |   . .   || |||||| |||||   |||     |||| || ||  . |.|
TFQNPQPTAGLTLMDLVEMCIDISKGCEYLEDMHFVHRDLACRNCLVSVKDYTTHRRRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLMDGYF

TSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERL
|.  | |.||.| ||| .||  ||| . | ||| .|  ||| ..|| ||  .. .|.|||. .|. ||||  . . |
TTQSDVWAFGILCWEIMTLGHQPYPAHSNFEVLNHVQAGGRLQQPRMCPDDLWMMMRQCWRQDPWQRPSFHMCQNML
Kinase LTK.AA InsR 510-779 38 1.7e-105 355.37 In-house 1-278 (278) Show / Hide 
Range on Protein: 510-779
Range on HMM: 1-278/278
Sequence Identity: 38% (109 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPL--QVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRP
..|.| .| |.|| ||||.  |.. |      ..||||. |  |  . ..||.|| .  .| . ..||  |   |  | ..  |.|  || ||.||  ||
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

HLG-QPSPLV-------MRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGI
  . .  ..          ...| | .|. |  ||. . |.||| |.|||. .    .   |||||||.||||   |||.| . .||| ||.||   .|.
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNH---DFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGV

FTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFV-VGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQY
||.. | |||||.|||. .||  || |  | .||...  .|. ..|| .||  .. .| .|||. | .||.|  |.. |. 
FTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase LTK.AA UTK 510-777 37 1.8e-97 330.11 In-house 1-296 (296) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-296/296
Sequence Identity: 37% (110 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLP-ELCSPQDEL---DFLMEAL---IISKFR-HQNIVRCVGLSLRATPRLILLELMSGGDMKSF
| |.| ||.||||||... .   .. .  ..||.|..  .  ..|..    ||..||    . ..|. |.|..| ||. ..  | .|..|.|..||. |.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRHSRPHLG-QPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAG----PSRVAKIGDFG---MARDIY---------RASYYRRGDRAL
|| .|| .. .|  | ....|. | ||| | .||.. .|.|||.||||||.   .      .|.||.|||   |.|...          . ||.. ..  
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVKWMPPEAFLEG-IFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGG--RMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERL
.|..|| |||. ..  ||.|.| |||||..|||.. | .|||| .|..|. .|. ||  || .|..|| ||||.|..||. .|. ||.|  .....
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase LTK.AA TK-Unique 510-777 35 4.1e-87 295.73 In-house 1-294 (294) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-294/294
Sequence Identity: 35% (106 aa)

VTLLRALGHGAFGEVYEGLVIGLP-GDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFR-HQNIVRCVGLSLRAT-PRLILLELMSGGDMKSFLRHSR
..... .| ||||.|. | | |.. ... . .||.|.| .  ...|. ||| |. . ..   |.|||.|.| . . . | .|..| ...|.  ..|| .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-------------------PHLGQPSPLVMRDLLQLAQDIAQGCHYLEE--NHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIY-RASYYRRGDRAL
                   |.  ...|. ..||.. | .||.|  ||..   ...|||..|||.||.      |.||.|||||||.| .  | . . .  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE---DKVCKICDFGMARDVYTNGVYSMMCSQGR

LPVKWMPPEAFL--EGIF-TSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGC-PGPVYRIMTQCWQHEPELRPSFASILERL
.|..||.||...  .|.. |.|.| ||||||.||||.|| .||||  . .... .  | ||. | .| .  .| .| .|||.||| ||||..|. ||
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase LTK.AA Trk 510-777 37 2e-83 282.66 In-house 1-275 (275) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-275/275
Sequence Identity: 37% (106 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHL
. | . || |||| |. .    |...  .. ||.||| .    .   ||  || .  .  ||.||.  |.     | |.  | |  ||.. .||   |  
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

-----GQP----SPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYR-ASYYRRGDRALLPVKWMPPEAFLEGI
     .||     ||.. ..|  |..|| |  |. . ||.|||.|.||||    |   . ||||||| ||.|    ||| | .  ||. |||||. .   
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCL---VGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRK

FTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGR-MDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERL
||   | ||||| .||.|. |  |. .  |.|| ...  |   .. ||.||  || ||  ||| ||. | .  .| ...
FTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase LTK.AA Src 510-777 40 4.7e-79 268.22 In-house 1-255 (255) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-255/255
Sequence Identity: 40% (109 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHL
..|.| || | ||||..|.  |        .||.||| .     .  .|| || |  |.||...|.      .  | .|  |.|| |    .|..     
IKLCRKLGQGQFGEVWMGYWNGN------TKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----D

GQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIY--RASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSW
|. . | ...|. .|  .|.|  |||.. .|||| |||| | .      |.|..||| || |      |  | . | .|.||. |||...| || |.| |
GEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN---VCKVADFGLARLIKEDDDEYCARHG-AKFPIKWTAPEAINYGRFTIKSDVW

SFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYR-IMTQCWQHEPELRPSFASILERL
|||.||.||.. | .|||| ||.|||. |  | ||  |..||  .|  ||.|||. .|| || |. . . |
SFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase LTK.AA CTKB 510-779 39 8.9e-76 258.06 In-house 1-269 (269) Show / Hide 
Range on Protein: 510-779
Range on HMM: 1-269/269
Sequence Identity: 39% (109 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFR-HQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPH
. |   || | || || |    .  |     |||| | .  |     ||. |  |.      | ||| .|.  | || |. ||||  ||.|  || ||| 
IVLKQKLGEGHFGVVYAGEAKKIMPDQAVTPVAIKMLQDSSS-EATNDFMKEVKIMQTIDGDQKIVRLLGICTRETPFLMVLELMAKGDLKTLLRNSRPK

LGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWS
  .|| |  | |  .| |.| |  |.     .||| ||||||       .   |||||. ||.|   ||     . ||. || ||.   |..|.  | ||
TSKPSALSPRRLALMAADVADGMAYIASKRIVHRDLAARNCLVHQNWRVC---IGDFGISRDVYMREYYKMQASNPLPIRWMSPESINDGVYTTQSDVWS

FGVLLWEIFSLGYMPYPG-RTNQEVLDFVVGG-GRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQY
.|...|||   . ||||.  ||.||   .  .  ||  |..||  .|  |.|||  ||. |.||    |..  
YGIVIWEIMTFAKMPYPEYETNMEVVERICDEDYRMWQPKECPDEFYDLMMQCWDEEPDDRISFKELHEKTLL
Kinase LTK.AA Fer 510-778 33 1.7e-73 249.59 In-house 1-283 (283) Show / Hide 
Range on Protein: 510-778
Range on HMM: 1-283/283
Sequence Identity: 33% (96 aa)

VTLLRALGHGAFGEVYEG---LVIGLPGDSSP--LQVAIKTL-PELCSPQDELDFLMEALIISK-FRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFL
|||   || ||||||| |   | ..... . .  . |. |..  |. .     .|. || |. . . | |.|.. | .    | .|..|...||. .|.|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAK--IGDFGMARD--IYRASYYRRGDRALLPVKWMPPEAFLEG
...         . ...... . ..|.|  ||.... |||||||||||..      . |  | ||||.|.   |  .|. .     .|..|..||..  |
KKNKNK-----TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYH--KDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTG

IFTSKTDSWSFGVLLWEIFSLGYMPYPG----RTNQEV-----LDFVVGGGRMDPPRGCPGPVYRIMT-QCWQHEPELRPSFASILERLQ
|...||| |||||..||||. |. ||||     .. .|        ...| .| .| ..| ....||. ||||..|| ||....| ..| 
IYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase LTK.AA S_TKc 510-779 22 9.5e-36 126.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 510-779
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSG--GDMKSFLRHSRP
 ..|| .|.||||.|| .  ..     .  .|||| ..         ... |  | .| .| |||.. .     .   . .|...|  ||....... ..
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

HLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTS-KTDS
| .. .|.   .   ... |...  |. ....||||.   | ||.      . ||.|||.|| .         .       .|.|| .    ..  | | 
HGLR-FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDW

WSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILE-------RLQY
||.|..|.| .. || |.|  . |.... ..           . ..  .. .|.| .|| ||.   .|.           
WSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LTK.AA Pkinase 510-777 18 3.1e-21 76.16 Pfam 1-293 (293) Show / Hide 
Range on Protein: 510-777
Range on HMM: 1-293/293
Sequence Identity: 18% (59 aa)

VTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDEL---DFL-MEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGG----DMKSF
 ...| .| |.||.||..  .| .      .||.|...   .  ..    ... .|. |  ...| ||||. .   . .   . .|.. ||    | ...
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LR-HSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVA---KIGDFGMARDIYRASYYRRGDRALLPV---KWMPPEA
.. ...  .   . . ....   .  |..|  |. .. .||||.   |.|..      ..   ||.||| |. ..    | ..  .  ..    .|.|| 
ISTWRHGCF---Y-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEV

FL-EGIFTSKTDSWSFGVLLWEIFSLGYMPYPGR----TNQEVLDFVVGGGRMDPPRGCP-----------------------GPVYRIMTQCWQHEPEL
 .     ..| | ||.|..|.| .. |. |.||.    .  . .  ..  .. .... .|                        .   ... |..  |. 
IRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK

RPSFASILER--L
||... ||.   .
RPTAEQILQHPWF