LMR3

Species: Human
Alias: LMTK3, TYKLM3, LMR3, KIAA1883
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 19q13.43,

Classification

Group: TK
Family: Lmr

Sequence

Name Sequence Type Origin Length Description Download
LMR3.NA RNA Sugen Kinome 4972 None Fasta, JSON
LMR3.AA Protein Sugen Kinome 1460 None Fasta, JSON
LMR3.kin_dom Protein Kinase Domain Sugen Kinome 320 None Fasta, JSON

Protein domain

Protein domains of LMR3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LMR3.AA Lmr 133-411 65 1.1e-227 762.65 In-house 1-283 (283) Show / Hide
Range on Protein: 133-411
Range on HMM: 1-283/283
Sequence Identity: 65% (186 aa)

LSYLQEIGSGWFGKVILGEIFS---DYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPE
|.|.||||.||||||.|||..|   ....||||||||||||.|.||..|..|.||||.|||||||||||.||||.|.||.||||..||||.|||..||.|
LNYIQEIGNGWFGKVLLGEVHSLHPGMSKAQVVVKELRASASPQEQMQFLQEVQPYRELQHPNVLQCLGQCVETIPYLLVMEFCPYGDLKNYLRKCRPME

GLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPER-LWIPLRWAAPELLGELHGTFMVVDQS
...|..|||...|||||..|||.||||.|.|..||||||||||.|..||||.||||||||..||||||.|... .|.||||.||||..|.|....||||.
HMMPDKPPRQTMTLQRMACEIACGLAHMHQHHFVHSDLALRNCQLCADLTVKIGDYGLAHCQYKEDYYITKDQCHWVPLRWIAPELMDEFHQNLLVVDQT

RESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYL
..|||||||||.||||||.||||.|.|||.|||.|||.|..||..|.|.|||.|.||.|.|.||..|.|||.|.|....||||
KYSNIWSLGVTMWELFEFAAQPYPHHSDEQVLAQVVREQDIKLPKPQLQLPYSDRWYEIMQFCWMQPDQRPTAEDVHRLLTYL

Kinase LMR3.AA TK 133-408 18 9.5e-88 294.17 In-house 1-486 (486) Show / Hide
Range on Protein: 133-408
Range on HMM: 1-486/486
Sequence Identity: 18% (92 aa)

LSYLQEIGSGWFG---KVILGEIFS-----------------------DYTPAQVVVKELR--ASAGPLEQRK--------------FISEAQPYRS--L
. .....|.|.||   .| .|| ..                       . .. .| || |.  ... . |..               . .|..  ..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHPNVLQCLGLCVET------------LPFLLIMEFCQLGD----LKRYLRAQRPPEGL-----------------------------------------
.|||.....| |..              |....||....||    |. |||. ||..                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------SPELPPRDLRTLQR----------------MGLEIARGLAHLHSH------NYVHSDLALRNCLLTSDLT-----------VRIGDYG----
        .|.|. .||  ...                | . ||.|...|||.      |.|| ||| ||||......           ..|.|.|    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LAHSNYKEDYYLTPE------------------------RLWIPLRWAAPELLGELHGTFM--VVDQSRESNIWSLGVTLWELFEFG-AQPYRHLS
    ||   |..|.| . .                        . ..|.|| ||| | . . .        . .| .||.||..||.| .| ...|  .|
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

D---------EEVLAFVVR----------QQHVKLARPRLKLPYA-------------DYWYDILQSCWRP-PAQRPSASDLQLQL
.         .||. ...|          ..  .. .|. ..                . .||..|.||.. |..||. |.|. ||
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase LMR3.AA Pkinase_Tyr 133-408 32 1.1e-75 257.01 Pfam 1-270 (270) Show / Hide
Range on Protein: 133-408
Range on HMM: 1-270/270
Sequence Identity: 32% (94 aa)

LSYLQEIGSGWFGKVILGEIF--SDYTPAQVVVKELRASAGPLE--QRKFISEAQPYRSL-QHPNVLQCLGLCV-ETLP--FLLIMEFCQLGDLKRYLRA
.. ....|.| ||.| .|. .   | |  .| || |. .| . .  ...|..||.  ..| .|||.....| |. .  |   ...||....|||. |||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

QRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYY-LTPERLWIPLRWAAPELLGELHGTFM
.|      .. .| .. .|  | ..||.|...|.|.|..| ||| ||||.|....|.|.| |||   |..|||  . .   .| .| ||| . .      
HR------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK----

VVDQSRESNIWSLGVTLWELFEFGAQP-YRHLSDEEVLAFVVRQQHVKLARPRLKLPY--ADYWYDILQSCW-RPPAQRPSASDLQLQL
    . .| .|| ||..||.| .|.|| |  .|.|||.... ..      . |.. |    |  ||....||   |..||. |... ||
---FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED------GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase LMR3.AA TyrKc 133-408 30 2.1e-71 244.43 SMART 1-280 (280) Show / Hide
Range on Protein: 133-408
Range on HMM: 1-280/280
Sequence Identity: 30% (94 aa)

LSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSL--QHPNVLQCLGLCVET-------LPFLLIMEFCQLGDLKRYLR
.. ....|.| ||.| .|.        || || |...|    .. |..||.  ..|  .|||.....| |..         | ...||.. .|||| |||
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

AQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKE-------DYYLT----PERLWIPLRWAAP
. ||            ...|  . . ||.| ..|||.|..| ||| ||||.....||.|.| ||.   | .       ||| .     .. ..|.|| ||
KHRPK---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

ELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRH-----LSDEEVLAFVVRQQHVKLARPRLKLP-----YADYWYDILQSCWRP-PAQRPSA
| .   .|.|     . .| .|| ||..||.| .|.|||       .|..||...| .     . .|   .|       |  |.| ..||.  |..||. 
ECI--NYGKF-----TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY--RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF

SDLQLQL
|..  ..
SEIHECF

Kinase LMR3.AA UTK 133-408 27 8.6e-69 234.45 In-house 1-296 (296) Show / Hide
Range on Protein: 133-408
Range on HMM: 1-296/296
Sequence Identity: 27% (83 aa)

LSYLQEIGSGWFGKVILGEIFSDY---TPAQVVVKELR-ASAGPLEQR---KFISEAQ---PYRSLQ-HPNVLQCLGLCVETLPFLLIMEFCQLGDLKRY
.  ....|.| || | ...   .    . ..| ||...  .... |..   .|. ||.    .  .. |||||. .|.|.   |.....|... |||  |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSD-------LTVRIGDYG---LAHSNYK--------EDYYLTPE-R
|| .||  .  ..    .|...  | . ||||...|||...|| ||| ||||....       ....|.|.|   ...  .         |.|| ..  .
LRRHRPTPP--ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQ

LWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRP-PAQRPSA
  .|.|| ||| | .        . .. | .||.||..||.. .|..|| ..|...|...|... .  ...|.      .  |.....||.. |. ||..
DRWPIRWMAPEALTHHT------RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPW---DCPHPVYRLMHRCWHYDPQERPDF

SDLQLQL
 ||  |.
EDLVQQM

Kinase LMR3.AA TK-Unique 133-360 33 1.4e-56 193.65 In-house 1-249 (294) Show / Hide
Range on Protein: 133-360
Range on HMM: 1-249/294
Sequence Identity: 33% (86 aa)

LSYLQEIGSGWFGKVILGEIFS----DYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQ-HPNVLQCLGLCVETL-PFLLIMEFCQLGDLKRYLRAQR
|  ...||.| || |. ||...    .  . .|.|| |...| ......| .|.| ...|  |||..|||| |...  |...|||.|. |.|  |||  |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

P------------------PEGLSPE-LPPRDLRTLQRMGLEIARGLAHLHS--HNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTP-ERLW
|                  |.. ..| . |.|| .    . .||.|...|.|  .. || ||. ||.|||.|... |.|.|.|   |..  | .  ..  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYH---FAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR

IPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVL
||.|| ||| | . ||..     . .|..||.||..||.| .||.||. .......
IPIRWMAPESLKCYHGMYH----TTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIM

Kinase LMR3.AA InsR 133-410 33 5.6e-56 186.46 In-house 1-278 (278) Show / Hide
Range on Protein: 133-410
Range on HMM: 1-278/278
Sequence Identity: 33% (97 aa)

LSYLQEIGSGWFGKVILG---EIFSDYTPA--QVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRP
.  ..| | | ||.| .|    | .|   .  .. .| . ..|   |   | .||       . .|   || |    | . .||. ..|||| |||. ||
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

PEG-LSPELP----PRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTF
 |.   | ..    .  |  .  |  ||. |.| | . ..|| ||| |||.   |.|| ||| |..   |  |||    .   | || ||| | .  | |
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKD--GVF

MVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYA--DYWYDILQSCWRP-PAQRPSASDLQLQLTY
        | .||.|| |||   .|.|||  || |.|| .. .   |      |. |    .||... . ||.  |  ||.. |.   |  
TT-----HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNV------LRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD

Kinase LMR3.AA Trk 133-408 32 1.9e-50 169.23 In-house 1-275 (275) Show / Hide
Range on Protein: 133-408
Range on HMM: 1-275/275
Sequence Identity: 32% (92 aa)

LSYLQEIGSGWFGKVILGE---IFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPE
.   .|.| | ||||.|.|   .  .  .  | || |.  .     . |  ||.    |||... .  |.|..  |.|.. |. . |||..|||.. |  
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

GLSPELPP------RDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYK-EDYYLTPERLWIPLRWAAPELLGELHGTF
 .  . .|        .  .     .|| |.  . |  .|| |.| ||||   .| |.|||.|.    |   |||    .   | ||  ||    .  .|
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESI--MYRKF

MVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCW-RPPAQRPSASDLQLQL
 .     || .||.||..|| |..| ||.  ||  ||  ..  |  ..| ||| . |     |||.  || | | || .. |.   .
TY-----ESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIH-QGRHRLERPR-RCPQE--VYDIMLGCWQREPQQRMNIKDIHDII

Kinase LMR3.AA CTKA 133-408 32 2.2e-42 140.15 In-house 1-290 (290) Show / Hide
Range on Protein: 133-408
Range on HMM: 1-290/290
Sequence Identity: 32% (99 aa)

LSYLQEIGSGWFGKVILGEIFSDYT--------PAQVVVKELRASAGPLEQRKFISEAQPYRS---LQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRY
.    .||.| .| |       |             | || |.. |   . | |  ||   .|   . |||||  ||.|    | . |||. |.|||. |
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAF-VLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCY

LRAQRPPE----------GLSPELPPRDLRTLQR--MGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKE-DYYLTPERLWIPLR
||| ||             .     |  ...     |  .|| |   | .   || ||| ||||| .  .. | | |..     |  ||    .  .| |
LRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVR

WAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLAR--PRLKLPY--ADYWYDILQSCWRP-PAQRPSASD
| ||| | .  |.|     |  | .|. || |||.. .|  |.||.|| ||   .       ..    ||..|   ..  |   | ||.. |.|||.   
WMAPEALCF--GKF-----SCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAY-------TSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFET

LQLQL
||  |
LQRML

Kinase LMR3.AA DDR 133-408 28 3.7e-41 141.24 In-house 1-306 (306) Show / Hide
Range on Protein: 133-408
Range on HMM: 1-306/306
Sequence Identity: 28% (89 aa)

LSYLQEIGSGWFGKVILGEIFSDYT------PAQ--------VVVKELRASAGPLEQRKFISEAQPYRSLQ-HPNVLQCLGLCVETLPFLLIMEFCQL-G
|  .  ||.| || | | |...         . .        | || ||. |     . | .|.    ..  |||.   .| |..  | ..|||.    |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLKRYLRAQRPPEGLSPELP---------PRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYG--LAHSNYKEDYYLTPE----
||. .. .. ...  . ...           .   . ...  || |...| | | || ||| ||||   .....| | |  .. . |  |||        
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

-RLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFG-AQPYRHLSDEEV-----LAFVVRQQHVKLARPRLKLPYADYWY-DILQSCWR
 |   |.|| |.| .  | | |     .  | .|. |||.|| | |  .||| .|.|| |     . |     .| |..|..     .  | . . .|||
QRHHMPIRWMAWESI--LLGKF-----TTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPM---CPYEIYNQLMCRCWR

P-PAQRPSASDLQLQL
  . |||| . . . |
RDQSQRPSFEEIHKFL

Kinase LMR3.AA Musk 133-363 31 5.1e-41 133.13 In-house 1-241 (282) Show / Hide
Range on Protein: 133-363
Range on HMM: 1-241/282
Sequence Identity: 31% (79 aa)

LSYLQEIGSGWFGKVILG---EIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRP--
  | ..|| | || |          .     | || |.. |    |  |  ||.      |||. . || |    |  | .|.   |||  .|..  |  
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHR

PEGLSPELP----------PRDLRTLQR--MGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELL
   .. . .          |  |... .  |  .|| |.| |    .|| ||| ||||  .   |.| |.||..  | .|||   |   || || .|| .
TCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESI

GELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFV
  .   |     . || .|. || |||.| .. |||  .. |||. ..
--WYNQF-----TYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYI

Kinase LMR3.AA Pkinase 133-408 18 3.8e-25 89.99 Pfam 1-293 (293) Show / Hide
Range on Protein: 133-408
Range on HMM: 1-293/293
Sequence Identity: 18% (58 aa)

LSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRAS-AGPLEQRKFIS--EAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLG----DLKRYLRAQ
.  .. |||| ||.| ..   ..    .|.||... . . . ...  .   |.|  ..|.|||...... . .     ..||.|. |    ||..|... 
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-

RPPEGLSPELPPR--DLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTV----RIGDYGLA--HSNYKEDYYLTPERLWIP---LRWAAPEL
        .  .   . ...... ..|.|||...||.. .| || . |.|. .. ..    .|.| |||  ..      |   . .. .   ....|||.
-------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEV

LGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHL----SDEEVLAFVVRQQHVKLARPRLKLPY------------------ADYWYDILQSCW
.          . .... .||.|..|.|..  |  |...     .  . .. ..|  . .| ... ..                     .   |.. .|.
IR------GGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

RP-PAQRPSASDLQLQ--L
.. |..||.| ..     .
CKDPKKRPTAEQILQHPWF

Kinase LMR3.AA Ror 250-351 45 9.1e-25 88.61 In-house 128-222 (308) Show / Hide
Range on Protein: 250-351
Range on HMM: 128-222/308
Sequence Identity: 45% (46 aa)

IARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQ
|| |   | || .|| ||| ||||    ..|.| | ||.   |  |||  . . | | || .||    . | |     | .| ||| ||.||| . .| |
IAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAI--MYGKF-----SEDSDIWSFGVVLWEIWSYGMQ

PY
||
PY

Kinase LMR3.AA S_TKc 133-1351 4 2.3e-15 48.43 SMART 1-231 (231) Show / Hide
Range on Protein: 133-1351
Range on HMM: 1-231/231
Sequence Identity: 4% (58 aa)

LSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQL--GDLKRYLRAQRPP--
   |..||.| |||| ..   .  |  .| .|...        .....| |  .. .|||. .... ...   . ..||.|    |||..|.. ....  
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-EGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQ
  ....          ...  .|...|...|||. .| ||   | ||..  .. |.| |||              .   . . |||.|            
RFPFPE-H-------ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----------GY

SR-ESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPPPPPP
.. .. .||.|..|.|..  |  |..   .....  ...                                                             
GKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG-------------------------------------------------------------

RDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPV
                                                                                                    
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ISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPA
                                                                                                    
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EVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPA
                                                                                                    
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SAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPE
                                                                                                    
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PPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGV
                                                                                                    
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TVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRA
                                                                                                    
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PGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGG
                                                                                                    
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PGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKA
                                                                                                    
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RLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPL
                                                                                            . .|   .
--------------------------------------------------------------------------------------------SPEAKDFI

RGLLK-SPR---GADEPEDSELERK-RKMV
|..|.  |.   .| |   .|.. |    .
RKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LMR3.AA Ror 133-218 28 2e-13 49.86 In-house 1-89 (308) Show / Hide
Range on Protein: 133-218
Range on HMM: 1-89/308
Sequence Identity: 28% (25 aa)

LSYLQEIGSGWFGKVILGEIFSDY---TPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDL
.. . |.| . ||||  |. ..     ..  |..| ..  | | ..  |  |..   .|.|||.   || |    | . . |..  |||
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDL

Kinase LMR3.AA Musk 385-408 28 0.007225 5.05 In-house 258-282 (282) Show / Hide
Range on Protein: 385-408
Range on HMM: 258-282/282
Sequence Identity: 28% (7 aa)

YDILQSCW-RPPAQRPSASDLQLQL
| ..  || . || ||.  ...  .
YQLMRRCWQKNPADRPFFCQIHHCI

Kinase LMR3.AA TK-Unique 385-408 36 0.046199 3.05 In-house 270-294 (294) Show / Hide
Range on Protein: 385-408
Range on HMM: 270-294/294
Sequence Identity: 36% (9 aa)

YDILQSCWRP-PAQRPSASDLQLQL
| ...|||.  | .||| ...  .|
YNLMKSCWQWEPEERPSFRQIKHRL