Gene KHS1 (Human)
KHS1
Sequence
Protein domains of KHS1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | KHS1.AA | KHS | 20-277 | 86 | 1.2e-204 | 686.21 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-258/258 Sequence Identity: 86% (224 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAY |||.|||||||||||||||.....||||||.||.||||||..|||||.|.|.|.|.||||||||||.|.||||||||||||||||||||||||||||||| YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIAY VCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMF |||||||||.|||..||||||||||||||||.||||||||||.|.||||||||||||||||||||||||||..|||||||||||||||||||.||||||| VCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPMF DLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV |||||||||||.||||||||||||.|||.|||.|||.|||||||||||||.||.|.|| DLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV |
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Kinase | KHS1.AA | STE20 | 20-277 | 51 | 1e-165 | 556.87 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-288/288 Sequence Identity: 51% (149 aa) YELVQRVGSGTYGDVYKARNVHTGEL----AAVKIIKLEPG----DDFSLIQQEIFMVKECKHCNIVAYFGSYLSR----EKLWICMEYCGGGSLQDIYH |||....|.|.||.||||....|||. .|.|...||. |.. .||.|| . |.||| |||.|.|||| ..|||.|||||||||.||.. YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK ---VTG------PLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITA----TIA-KRKSFIGTPYWMAPEVAAVEKN- ..| |..| ||||.|||.||||.||| ....|||||..|||||..|.||||||||.|..| |.. ||..|.|||||||||| . ... HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP -GGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKD--KTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV .||.. ||||..||||||. | .||.||.|||||.|.. |.. .||.||| ..|||. ||.||. |.|.|.|||||. ||.| |. DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI |
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Kinase | KHS1.AA | STE | 20-277 | 34 | 3.9e-132 | 445.27 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-359/359 Sequence Identity: 34% (126 aa) YELVQRVGSGTYGDVYKARNVH---------------TGELAAVKIIKLEPG-----------------DDFSLIQQEIFMVKECK--HCNIVAYFGSYL .|.....|.|..| ||||.|.. |||. |.|...||. ... |..|| . |.|. | ||| |.|.|. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF -------SREKLWICMEYCGGGSLQDIYH---VT-----------GPLSELQIAYVCRETLQG-LAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAA ....|||||||..|||| ||.. . ....| ||||.||..|.| |.||| ....|||||.||||| |||.||||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG KITATIA----------------KRKSFIGTPYWMAPEVAAVEKNG---GYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSN---------- ..| ..| ||..|.||| |||||| ...| ||. |||| .|.|.||. . .||..|.|||||.|.. ... QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ---FQPPKLKD-----------------KTKWSSTFHNFVKIALTKNPKKRPTAERLLT--HTFV ..||.|.| ..|||. |..|.. |.|.|.|||||. || | |. IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | KHS1.AA | YSK | 20-277 | 48 | 4.2e-127 | 384.88 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-257/257 Sequence Identity: 48% (126 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPG-DDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVT--GPLSELQ . ..| | .|.|||. ...|.. |.||| || |. .|||||. .|. .| |.|||| |||| ||||||||. | |.. | . FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY IAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKN-GGYNQLCDIWAVGITAIELGELQ || . || |.|| ||| | ||||| ||.||. ||||||.|||||..|| | || |.|||||||||| . .. .|. ||| .||||.|. . IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEV--ICQEVSYYDFKADIWSLGITAYEMAKGE PPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV || |.||||..|| |.| ||||... ..| | .|| . | |.|..||.|. || | |. PPYCDYHPMRVMFLIPKNN--PPKLEGR-SYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI |
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Kinase | KHS1.AA | MST | 20-277 | 47 | 1.2e-120 | 385.2 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-254/254 Sequence Identity: 47% (125 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYL--SREKLWICMEYCGGGSLQDIYHVTG-PLSELQ ...| . | | || |||| . ||.. |.|... . |.. | || . ..|| .|| |.|||. . .||.|||||.||. || |. .|.| | FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN--EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQ IAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQP || ... |||||.||| |.||||| .|||| | |||||||.. | | ||| ..||||||||||| . .|. |||. ||||||. | | IACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVI---QEIKYDCKADIWSLGITAIEMAEGMP PMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV | .|.|||||.|. .. ||..|| ..||. | .||. |.||| .|.|||.|| |.|. PYSDIHPMRAMFMIPQKP--PPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI |
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Kinase | KHS1.AA | PAKA | 20-277 | 41 | 2.5e-99 | 336.29 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-260/260 Sequence Identity: 41% (111 aa) YELVQRVGSGTYGDVYKARNVHTGEL--AAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTG-----PL |. .. .| | | ||.| |..|.. |.| .... . || || . ||||| ||| | ||| ..||. ||| .||.| |. . .. YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM SELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELG .| ||||||||.|||| ..| |. ||||| |||| |.||..||| .| .| ||.. |||||||||| . .. |.. ||| || |||. DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEV--IRRK-QYDEKVDIWSLGIMAIEMI ELQPPMFDLHPMRALFLMSKSNFQ-PPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV | .|| . | ||..| .. . |..||..|||..|..|.. | .....|..|. ||.| | EGEPPYLNEPPLRAMYLIAT---NGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL |
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Kinase | KHS1.AA | MSN | 20-277 | 49 | 1.4e-95 | 316.05 | In-house | 1-265 (265) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-265/265 Sequence Identity: 49% (134 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKE-CKHCNIVAYFGSYL------SREKLWICMEYCGGGSLQDIYHVT--G .|||. || |||| ||| | | ||.|||.|..... |. |.||| |.| | ||..|.| .. ...||. ||.|| ||. |. . | FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVR-EDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKGQ PLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKN--GGYNQLCDIWAVGITA | | |||.||| |.|||.||.. .|||||| |.|||. .||| ||||.|.. |. .| .|||||||||||| | . | | . |.|.||||| SLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITA IELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV ||. | |||. |.||||||||. . ||||| ||| ||||. | || ..||..|..| | |. IEMAEGQPPLCDMHPMRALFLIPRN--PPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI |
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Kinase | KHS1.AA | SLK | 20-277 | 42 | 7.3e-92 | 310.2 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-259/259 Sequence Identity: 42% (110 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIY-HVTGPLSELQIA .|.. .| | .| ||||.. .. .|| |.|... ... . || .. |||| ||| ...| .|||. .|.|.|| . | . || | ||. WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ YVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVE--KNGGYNQLCDIWAVGITAIELGELQP |||......| .|| . .|||.| |||.| |||.||||||.|| . |. || .|||||||||||| . | | | |||..||| ||. .. | YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP PMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV | .. ||| |. . || .||.|. .||. |..|.|..| |.|..|.|...|. | .| PHHEMNPMRVLLKIQKS--EPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV |
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Kinase | KHS1.AA | S_TKc | 20-277 | 29 | 2.1e-90 | 307.58 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-231/231 Sequence Identity: 29% (82 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGG--GSLQDIYHVTGP------ ||... .|.|..| |||.|...||.. |.|||| |..|| . |. .| ||| ..... . ..|...||||.| |.| |. . |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP LSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQ-LCDIWAVGITAIE ..| ............|.|.| .| .|||.| .||||.. .|..|||.|... ..|.|||..||||| ||. ||.|..|.. .| FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYE LGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLT-------HTFV . .|| .... . .. |. . .|.. |.|.|.||||| .|. | .. MLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | KHS1.AA | PAKL | 20-277 | 40 | 1.4e-81 | 277.34 | In-house | 1-256 (256) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-256/256 Sequence Identity: 40% (107 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSR-EKLWICMEYCGGGSLQDIYHVTG-PLSELQI .|. | | || |||| |. |.| | . . . |. || . | || ||| |||| . ..|| |.|| || |. ... | | || FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI AYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIA-KRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQP . . . || || ||| |. ||||| |||||. ..||.||||| .. . .. ||||||||||. . || |||| ||||||. . | SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEII---NKQNYNNKCDIWSLGITAIEMADGFP PMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV | |. ||||. | ||.... .|| | .|. ..| | ||. . ||.| | PHYDMPPMRAMYMI--PNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI |
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Kinase | KHS1.AA | NinaC | 20-277 | 40 | 1.7e-77 | 263.79 | In-house | 1-267 (267) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-267/267 Sequence Identity: 40% (110 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKE-CKHCNIVAYFGSYLSREK-----LWICMEYCGGGSLQDI----YHVT .| . .| |||| |.|. | |..||||| | . | | .. | | |.| ..| | .| ||. |||| ||| |. . WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEE-IEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCG GPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEK--NGGYNQLCDIWAVGIT ..| |||. .|.. || || .|||.|| ||||| | ||| |||| | .. | .| .|||.|||||| | .. . | ||.|. ||| RRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGIT AIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV ||||| ||..|.|||||.| ||.| ..|. | |. |.|. |||. .| | |. AIELGDGDPPFADMHPMRAMFKIPRNP--PPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI |
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Kinase | KHS1.AA | Pkinase | 20-277 | 29 | 5e-73 | 253.71 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 20-277 Range on HMM: 1-293/293 Sequence Identity: 29% (89 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQ-----EIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGG----SLQDIYH--V |......|||..| |||.... ||.. ||||||.. ... . |. || . |...|.||| ..... .. .....||||.|| .| |. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR TGPL--SELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDV----KLADFGVAAKI-TATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDI |.. || .. .....|.||.|.| .| .|||.| .|||. ..|.. |..|||.|... . ..| |||..||||| . .. .| . .|. HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVDM WAVGITAIELGELQPPMFDL---HPMRALFLMSKSNFQPPKLKDKTKWS--------------------STFHNFVKIALTKNPKKRPTAERLLTHTFV |..|.. .|. .|| . .. . | . . .|| | .|. ... |.| |.|.|||||||| .| | .. WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | KHS1.AA | Pkinase_Tyr | 20-207 | 26 | 2.6e-17 | 59.23 | Pfam | 1-203 (270) | Show / Hide |
Range on Protein: 20-207 Range on HMM: 1-203/270 Sequence Identity: 26% (55 aa) YELVQRVGSGTYGDVYKARNV----HTGELAAVKIIKLEPGDD---FSLIQQEIFMVKEC-KHCNIVAYFGSYL-SREK--LWICMEYCGGGSLQDIYHV .. . |.| .|.|||.. |. |||..| .. .|. . |. .| ||| . | . .| ..| |||. .|.| | . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK ----TGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKI-----TATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLC .||. .. |.. .|..||. |. |||. |.|.|. . || .||| | | . .. .. |||||. . | .. HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECINYGK---FTTKS DIWAVGIT |.|. |.. DVWSFGVL |
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Kinase | KHS1.AA | TyrKc | 20-276 | 23 | 1.4e-16 | 45.37 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 20-276 Range on HMM: 1-280/280 Sequence Identity: 23% (68 aa) YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKEC--KHCNIVAYFGSYLSR-------EKLWICMEYCGGGSLQDIYHVTG .| . |.| .| |||.. . ||| .| . . .|. . .. .| |||. .| .. | |.| |||. .|.|.| . .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR P-LSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITAT-------IAKRKSF-IGTP-----YWMAPEVAAVEKNGGYN | |. . . | .| .||| |. |||. |.|... . || .||| . .|. .||. |. |||||. . | .. PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFT QLCDIWAVGIT---AIELGELQPPM-----FDLHPMRALFLMSKSNFQPPK-----LKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTF |.|. |.. .|. .| . .... . ||| .. .. | .|..||| . . . | TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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CNH | KHS1.AA | CNH | 511-826 | 34 | 2.2e-145 | 490.19 | SMART | 1-375 (375) | Show / Hide |
Range on Protein: 511-826 Range on HMM: 1-375/375 Sequence Identity: 34% (129 aa) CATSWIHPDTKDQ----YIIFGTEDGIYTLNLNEL----HEATMEQLFPRK---CTWLYVINNTLMSLSVGKTFQLYSHNLIALFEHAKKPGLAAHIQTH |...|.|| |.|| ....|||.|||.||.|.. ||.|.|....|. |.|.|..||.||..| ||...||||.|..||......|...|||.| CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMIS-GKKPHLYSHPLVWLFQKYRTQGMTPHIQDH RFPDRILPRKFALTTKIPDTKG-CHKCCI-VRNPYTGHKYLCGALQSGIVLL-QWYEPMQKFMLIK--------------HFDFPLPSPLNVFEMLVIPE .......|||...||||||||| ||.||. .....||...||.|.|. .... |||.||.|||..| ||.||...|..||....... MCNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHDS QEYPMVCVAISK---GTESNQVVQFE-------------TINLNSASSWFTEIGAGSQQL--DSIHVTQLER------DTVLVCLDKFVKIVNLQGKLKS .|.|..|....| |......||.. |.|.|..|.||... . .||. ....|.|... |..|.| |.|...||..| ... FERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYG-SEW SKKLASELSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEV-TQEISDE----TRVFRLLG----SDRVVVLESRP .......|...|..|..........|||..|.|. ..|..|. ||.| |. .| ||||. .||.....|.| RRWRNPILHWEFMPEYFAYHYPYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP |
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CNH | KHS1.AA | CNH | 516-816 | 28 | 1.3e-106 | 365.27 | Pfam | 1-336 (336) | Show / Hide |
Range on Protein: 516-816 Range on HMM: 1-336/336 Sequence Identity: 28% (99 aa) IHPDTKDQYIIFG-TEDGIYTLNL----NELHEATMEQLFPRKCTWLYVIN--NTLMSL--SVGKTFQLYSHNLIALFEHA--K-KPGLAAHIQTHRFPD ..|.| .|....| |..|.|..|. ...|.....|.|.|..|..|||. | |... . .|. .||.|.| .|.. . .. .|..|||. . VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSRRVTQIYVIEEFNILIMISGC-DKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRI-E RILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQS-----GIVLLQWYEPMQKF-------------MLIKH-FDFPLPSPL-NVFEMLVIPEQ ||.|||||...|.||||.||..|..||.|.....||.|. . .|....||.||.|| ..... |..||| |. ..|.|.. | | RIMPRKFAMWQKLPDTKHCHFFCWIRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRECFYIPLP-PMTECFSMHWLP-Q EYPMVCVAISKGTESNQVVQFETINLN--SASSWFTEIGAGSQQLDS---------IHVTQLERD-TVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFR |.|..||. ..|. .||. ....|. . |.|.| |.......| ..|.| | ....||.||...|.| . .|. ... EKPKLCVGC--------QKGFHIVNLDGTGQPWWLHDPADHSVQQDFMARRENCKPICMHRINDDEEFLLCYDECCVYVNKQGWPRSRK-HDWEIMWEGM IESVVCLQDSVLAFWKHGMQGKSFKSD-EV---TQEISDETRVFRLLGS ..|..|.....|||....... .... |. .|.|..... |...|| PQSFACCYPYLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS |