Gene IRAK3 (Human)
IRAK3
Sequence
Protein domains of IRAK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Death | IRAK3.AA | Death | 26-106 | 28 | 6.5e-20 | 69.1 | Pfam | 1-87 (87) | Show / Hide |
Range on Protein: 26-106 Range on HMM: 1-87/87 Sequence Identity: 28% (25 aa) GELCAVL-DSCDGALGWRGLAERLSSSWLDVRHIEKYVDQGK---SGTRELLWSWAQK---NKTIGDLLQVLQEMGHRRAIHLITNYG .||..| .... || ||..| |. ....|| . .... | |...|| | |. | |...|...|..||.|.....|... QKLCRLLDPDHHPGKDWRRLARKLGMSDNEIDQIEHD-QNPHDLRSQTYQMLWKWEQRHGKNATVDHLIEALRKMGRRDCAEKIQSWL |
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Kinase | IRAK3.AA | IRAK | 165-443 | 44 | 1.4e-173 | 582.92 | In-house | 1-317 (317) | Show / Hide |
Range on Protein: 165-443 Range on HMM: 1-317/317 Sequence Identity: 44% (142 aa) FHKDFLIGEGEIFEVYRVEIQNLT--YAVKLFKQEKKMQCKKHWKRFLS---ELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVG-D ||||..||||....|||....|.| ||||..|....|....||.||.. ||.|.....||||..|..|.||....||.||||.||.|.|||.| . . FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ TAP--LPWHIRIGILIGISKAIHYLHNVQPC-SVICGSISSANILLDDQFQPKLTDFAMAHFR---SHLEHQSCTINMTSSSSKHLWYMPEEYIR--QGK ..| |.||.|. |..|....|..||...|| ..|.| |.|||||||..|.||..||....|. ||.|.|..|..||| ...||||.|.|| ||. CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ LSIKTDVYSFGIVIMEVLTGCRVVLDD-PKHIQLRDLLRELMEKRG-LDSCLS----------------------FLDKKVPPCPRNFSAKLFCLAGRCA |..||||||||||..|||||||.|.|| |.|..|.||..|.||..| ||||.| |.|...||||.|........|..|. LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQCACCCG ATRAKLRPSMDEVLNTL ..||..|..|..|...| HHRANRRCDMAWVMQQL |
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Kinase | IRAK3.AA | TKL | 171-443 | 20 | 8.1e-62 | 211.69 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 171-443 Range on HMM: 1-364/364 Sequence Identity: 20% (76 aa) IGEGEIFEVYRVEIQN----------LTYAVKLFKQ------EKKMQC-----------------KKHWKRFLSELEVLLLFHHPNILELAAYFTETEK- ||.| |||. . .. . ||| ||. .|..|. .. ... |. ... ..||||. . .| .. .. IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG ------------FCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQP-----CSVICGSISSANILLDDQFQ------------- .|... |. .|.|...|. || |. . ..|.....|||. .| . .| . |.|||.|. .. CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW -PKLTDFAMAHFRSHLEHQSCTINM------------TSSSSK-HLWYMPEEYIR----------------QGKLSIKTDVYSFGIVIMEVLTGCRVVLD .|..|| . | |. .....| .. |... .. .|. | .| ... | |.||||||||. |.||.||. | CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD DP-KHIQLR---DLLRELMEKRGLDSCLS------FLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTL .| .... .. .. ..|| . . | . ... .. . |. .| .. .. |||..|.| .| YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | IRAK3.AA | TK | 165-443 | 13 | 1.9e-26 | 85.03 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 165-443 Range on HMM: 1-486/486 Sequence Identity: 13% (67 aa) FHKDFLIGEGE---IFEVYRVEIQNL---------------------------TYAVKLFKQEKKMQCKKHWK-------------RFLSELEVLL--LF . .|||. |||. | ... . ||| | . |. . . ....|..... |. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG HHPNILELAAYFTET------------EKFCLIYPYMRNGT----LFDRLQ-CVGDTAP----------------------------------------- |||||. | .. |. | .... || .| | | |. | ... . HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -------------------------------LPWHIRIGILIGISKAIHYLHNVQPC----SVICGSISSANILLDDQFQ-----------PKLTDFAMA |. | .. . |... ||| ..| .. . . |.|.... . |..|| .. DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHS-KNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS ------HFRSHLEHQSCTINMTSSSSKHLW----------------------YMPEEYIR---------QGKLSIKTDVYSFGIVIMEVLTGCRVVLDDP . | . ... . . . .. .| .|. | .. || ..|.||.|||... |..| ... RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG KHIQL----RDLLRELMEKRGLDSCLSF-------LDKKVPPCPRNFS--------------AKLFCLAGRCAATRAKLRPSMDEVLNTL . | ..|.||. . | . .. .|.| . . . .. | .| . .. ||....... | MSNQDVWKDG-DNQEVMEYLRRGGRL-CRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | IRAK3.AA | TKL-Unique | 170-372 | 25 | 9e-22 | 73.67 | In-house | 4-226 (290) | Show / Hide |
Range on Protein: 170-372 Range on HMM: 4-226/290 Sequence Identity: 25% (58 aa) LIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFH-HPNILELAAYFT----ETEKFCLIYPYMRNGTLFDRLQ-------CVG .||||. .||... .|.| |. . . .. . | .|. .. .| ||||. . .| . ..|.. |. |.| | |. KIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN DTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQ-----FQPKLTDFAMAHFRSHLEHQSCTINMT-----SSSSKHLWYMPEEYIR . .|.. |. . | |... .|||. .| .| . . | |.|.| .. |. || . |.| |.|. .. . . .|. | .| NNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKM--TNNEHKGTRNQTRCGSFRWMAPEVLR Q--GKLSIKTDVYSFGIVIMEVLTGCR . . |.| |||||||| | .|... MNFCQYSEKSDVYSFGIVLWEIATRKI |
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Kinase | IRAK3.AA | TK-Unique | 209-369 | 21 | 1.2e-18 | 60.99 | In-house | 50-234 (294) | Show / Hide |
Range on Protein: 209-369 Range on HMM: 50-234/294 Sequence Identity: 21% (40 aa) FLSELEVLLLFH-HPNILELAAYFTET-EKFCLIYPYMRNGTLFDRLQCVGDT-----------------------APLPWHIRIGILIGISKAIHYLHN ||.|.... ||||. . . |.. | ...|..|...|.| . |. ... .|. . . ....| .. ||. FLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLAS VQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIR--QGKL-SIKTDVYSFGIVIMEVLT |.. .. . ... |.|| . .. |..|| || .... ...|.|.. .. .|. |... .| ..|.||.|||... |..| -QRKKIVHRDLCARNVLLTEDKVCKICDFGMA---RDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT |
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Kinase | IRAK3.AA | Pkinase | 165-370 | 22 | 1.8e-15 | 55.8 | Pfam | 1-208 (293) | Show / Hide |
Range on Protein: 165-370 Range on HMM: 1-208/293 Sequence Identity: 22% (50 aa) FHKDFLIGEGEIFEVYRVEIQNLT--YAVKLFKQEKKMQCKKHWKRFL-SELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNG----TLFDRLQCVG .|. ||.| .||. .. .||| .| . . ..|. ... ||..... ..||||..| .|.. . ... .|...| |||... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-W DTAPL--PWHIRIGILIGISKAIHYLHNVQPCSVICGSIS-----SANILLDDQFQP----KLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYI . .. ... . .. | ... |.|. .| ..|||.|.. .. |..|| | . . . ..| . . . .|||. | | RHGCFYFSEWECKFYMYQILRGLEYCHSM--------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGT----PWYMAPEVI R-QGKLSIKTDVYSFGIVIMEVLTG | . . . | |..|.|... |.|.| RGGQYYGPKVDMWSCGCILYEMLCG |
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Kinase | IRAK3.AA | TyrKc | 165-443 | 18 | 1.2e-14 | 14.05 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 165-443 Range on HMM: 1-280/280 Sequence Identity: 18% (58 aa) FHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLF--HHPNILELAAYFTET-------EKFCLIYPYMRNGTLFDRLQC ... .|||. |||. . .. ||| | .. . |..|.... . |||||. | .. |. | ... || .| | |.|. ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK VGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSC------TINMTSSSSKHLW------YMPE ... |.. . . . |.. ||| .| . |.|...... | .|| .. .. . . .....|. |. HRPK--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLS-----RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP EYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKH--IQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRN--------FSAKLFCLAGRCAATRAKLR | |. || ..|.||.|||... |..| . .. . ..... ... . . |.| | ..... . .| . .. | ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRM------------PQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR PSMDEVLNTL |.. |. . PTFSEIHECF |
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Kinase | IRAK3.AA | S_TKc | 165-452 | 19 | 1.1e-13 | 23.6 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 165-452 Range on HMM: 1-231/231 Sequence Identity: 19% (57 aa) FHKDFLIGEGEIFEVYRVEIQN--LTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRN--GTLFDRLQCVGDTA ... .||.| .||.. . .|.| | .....|...| ||||| | .| . ...... |. . |.|||... | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG P---LPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSI-KTD . .| .. | .|. |.|. . .| . .|||||. . |..|| .| . .. .|||. | . . . | | LRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCD VYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYF ..|.|... | |.|. |. ... .. | . . .| . ||. |.|. . . .| WWSCGCILYEMLCGYPPFP------QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | IRAK3.AA | Ciliate-E2-Unclassified | 165-370 | 15 | 1.7e-12 | 39.71 | In-house | 1-266 (352) | Show / Hide |
Range on Protein: 165-370 Range on HMM: 1-266/352 Sequence Identity: 15% (43 aa) FHKDFLIGEGEIFEVYRVEI--QNLT----YAVKLFKQEKKMQCKKHWKRFLSELEVLLL------------------FHHPNILELAAYFTETEKFCLI ... ||.| .||... |.. |. | .. .| . .|. ....|. . . ||.|. . .|. ....... YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV YPYMRNGTLFDRLQ---------------------------CVGDTAPLPWHIRI---GILIGISKAIHYLHNVQPCSVICGSISSANILLDDQ---FQP . |...|.|.. .. .. . .. | ... ||| . .| | |||.|.. ... MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKY-----------KKAKFYFAQILQGLEYLHHKN--NIIHRDIKPENILFDNNGKNYYI KLTDFAMAHFRSHLEHQSCT----------INMTSSSSKHLWYM----PEEYIRQGKLS----IKTDVYSFGIVIMEVLTG |..|| . . . . | .|... . . || . |.... . . .| |..|.|... | |.| KIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG |
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Kinase | IRAK3.AA | RIPK | 243-370 | 35 | 2e-12 | 38.6 | In-house | 83-224 (290) | Show / Hide |
Range on Protein: 243-370 Range on HMM: 83-224/290 Sequence Identity: 35% (51 aa) YMRNGTLFDRLQCVG--DTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFR--SHLEHQSC-TINMTSSSSKH || || | . |. |.|| | .. || . .|||. .| .| .|||.| | |. || | .. ||. | |. || YMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNPP-IIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKN ----LWYMPEEYIR--QGKL----SIKTDVYSFGIVIMEVLTG | ||| | .| . | . | |||||.||. ||||. RWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQ |
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Kinase | IRAK3.AA | TKL-ciliate2 | 165-286 | 28 | 3.7e-10 | 29.52 | In-house | 1-118 (273) | Show / Hide |
Range on Protein: 165-286 Range on HMM: 1-118/273 Sequence Identity: 28% (35 aa) FHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPW . | || .|. .. ||| || . | . . |..| . . |||| |. ||.| | | |. || . .| | LEIQNKITEGGYGIIYKAKWREIVVAVKKFKMDHDNQ--QQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQN--QDVRLTW HIRIGILIGISKAIHYLHNVQP | | . | . .|||| .| EDRRRIALDIARGVHYLHSSNP |
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Kinase | IRAK3.AA | UTK | 208-285 | 29 | 1.1e-08 | 25.81 | In-house | 52-138 (296) | Show / Hide |
Range on Protein: 208-285 Range on HMM: 52-138/296 Sequence Identity: 29% (26 aa) RFLSELE---VLLLFH-HPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAP-----LPWHIRIGILIGISKAIHYLHNVQ .|. | .. || |||.| | .. | | ..... ||.|| | . |. ..|.| | | |.. |. . .|||. . DFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG |
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Kinase | IRAK3.AA | Pkinase_Tyr | 203-283 | 26 | 1.3e-08 | 29.84 | Pfam | 42-129 (270) | Show / Hide |
Range on Protein: 203-283 Range on HMM: 42-129/270 Sequence Identity: 26% (23 aa) KKH--WKRFLSELEVLLLF-HHPNILELAAYFT-ETEK--FCLIYPYMRNGTLFDRLQCV-GDTAPLPWHIRIGILIGISKAIHYLHN ... .. |..|.... . |||||. | . | . | ... .|| .| | | |. | ||. . ... . |.|. ||.. HEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES |
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Kinase | IRAK3.AA | MLK | 171-312 | 20 | 3e-08 | 24.85 | In-house | 7-177 (291) | Show / Hide |
Range on Protein: 171-312 Range on HMM: 7-177/291 Sequence Identity: 20% (36 aa) IGEGEIFEVYRVEIQNLT-----YAVKLFKQEKKMQCKKH---WKRFLSELEVLLLFHHPN----ILELAAYFTETEK-FCLIYPYMRNGTLFDRL---Q ||.| .|.. . .| . ||| ..... . . | | . | . ||| | .. . ..... ||.. |...| |.. | . IGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGAR CVGDTA--------PLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDD------QFQPKLTDF .. | . . . . .....||||. .| .| . | |||.|. . . | .|| SKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDF |
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Kinase | IRAK3.AA | MLK | 346-370 | 48 | 1.1e-05 | 15.86 | In-house | 208-232 (291) | Show / Hide |
Range on Protein: 346-370 Range on HMM: 208-232/291 Sequence Identity: 48% (12 aa) IRQGKLSIKTDVYSFGIVIMEVLTG .| .| |.| ||.|.|.|. |.||. FRCEKYSEKCDVWSWGVVLWEMLTR |
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Kinase | IRAK3.AA | UTK | 339-370 | 37 | 1.3e-05 | 15.16 | In-house | 205-236 (296) | Show / Hide |
Range on Protein: 339-370 Range on HMM: 205-236/296 Sequence Identity: 37% (12 aa) WYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTG |. || .. . . ..|.||.|||.| .|..|. WMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW |
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Kinase | IRAK3.AA | Pkinase_Tyr | 346-372 | 40 | 2.4e-05 | 18.73 | Pfam | 186-212 (270) | Show / Hide |
Range on Protein: 346-372 Range on HMM: 186-212/270 Sequence Identity: 40% (11 aa) IRQGKLSIKTDVYSFGIVIMEVLTGCR |. || ..|.||.|||... |..| .. INYGKFTTKSDVWSFGVLMWEIFTYGE |
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Kinase | IRAK3.AA | TKL-ciliate2 | 294-367 | 32 | 0.00036 | 9.17 | In-house | 145-211 (273) | Show / Hide |
Range on Protein: 294-367 Range on HMM: 145-211/273 Sequence Identity: 32% (24 aa) ISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEV | | |.|.|| | ||||| . || | | | |. | ||.|..|.. |. INSLNVLVDDNFRCKLTDFGWTRVKPQDNY------MTNKIGTYQWMAP-EVIKAFYYTEKADVFSYSIILWEI |
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Kinase | IRAK3.AA | TKL-ciliate2 | 408-444 | 35 | 0.000385 | 9.07 | In-house | 237-273 (273) | Show / Hide |
Range on Protein: 408-444 Range on HMM: 237-273/273 Sequence Identity: 35% (13 aa) PPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLE | |.| .. | || ||||..|.. || PTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE |
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Kinase | IRAK3.AA | TKL-Unique | 433-443 | 54 | 0.187671 | 1.11 | In-house | 280-290 (290) | Show / Hide |
Range on Protein: 433-443 Range on HMM: 280-290/290 Sequence Identity: 54% (6 aa) RPSMDEVLNTL ||| ||... | RPSFDEIIHRL |
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Kinase | IRAK3.AA | MLK | 433-443 | 36 | 0.286055 | 0.32 | In-house | 281-291 (291) | Show / Hide |
Range on Protein: 433-443 Range on HMM: 281-291/291 Sequence Identity: 36% (4 aa) RPSMDEVLNTL |||..... | RPSFRQIVQHL |
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Kinase | IRAK3.AA | Pkinase_Tyr | 409-443 | 28 | 6.074057 | 0.43 | Pfam | 236-270 (270) | Show / Hide |
Range on Protein: 409-443 Range on HMM: 236-270/270 Sequence Identity: 28% (10 aa) PCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTL |||.| .... | .| . .. ||.. |... | PCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |