Gene HUNK (Human)

HUNK

Species: Human
Alias: HUNK
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 21q22.11,

Classification

Group: CAMK
Family: CAMKL
Subfamily: HUNK

Sequence

Name Sequence Type Origin Length Description Download
HUNK.NA RNA Sugen Kinome 7385 None Fasta, JSON
HUNK.AA Protein Sugen Kinome 714 None Fasta, JSON
HUNK.kin_dom Protein Kinase Domain Sugen Kinome 260 None Fasta, JSON

Protein domain

Protein domains of HUNK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase HUNK.AA CAMKL 61-320 40 4.6e-141 452.99 In-house 1-297 (297) Show / Hide 
Range on Protein: 61-320
Range on HMM: 1-297/297
Sequence Identity: 40% (121 aa)

YLIGSRKLGEGSFAKVREGLH-VLTGEKVAIKVIDKKRAKKDTYVTKN-----------LRREGQIQQMIR---HPNITQLLDILETENS------YYLV
| ||   ||.|||.||. ..|  .||||||||.||||....|....||           .||| ||..|..   |||| .|....||..       .|||
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MELCPGGN--LMHKIYEK----KRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN--NIKLIDFGLSNCAG-I-LGYSDPFSTQCGSPAY
||.|.||.  |...| ..    .|..|.||||| ||..|||...|. |.||||.| ||.||||..  |||.||||.||    .  |. . ..|.||||.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

AAPELLAR--K-KYGPKIDVWSIGVNMYAMLTGTLPFTVEP-------FSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRW
.|||....  |  .|||.|.||.|| .|||..|.|||  ..          . . ..|.. .. | . ..|  .....|..|...| |||.|.| .  .|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

L
.
M
Kinase HUNK.AA HUNK 61-212 70 2.8e-121 395.22 In-house 1-166 (433) Show / Hide 
Range on Protein: 61-212
Range on HMM: 1-166/433
Sequence Identity: 70% (117 aa)

YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKK--RL
||.|. |.|||||||||||.||||||||||||||||..|||.||.||||||.||.||.|||||..|....||.|.||||||.||||.||||..|||  ||
YLLGD-KIGEGSFAKVREGMHVLTGEKVAIKVIDKKKIKKDDYVHKNLRREAQIMQMMRHPNIVRLYEVMETDNNYYLVMEYCPGGDLMHKVCEKKGGRL

EESEARRYIRQLISAVEHLHRAGVVHRDLKIEN--------LLLDEDNNIK-----LIDFGLSNCAG
||..||||||||.|||.|.|..|||||||||||        ||||.|.|||     .||||||||.|
EEGVARRYIRQLVSAVHHMHHHGVVHRDLKIENLETYLSLSLLLDDDHNIKNYVAFIIDFGLSNCCG
Kinase HUNK.AA CAMK 67-320 26 2.2e-118 383.27 In-house 1-425 (425) Show / Hide 
Range on Protein: 67-320
Range on HMM: 1-425/425
Sequence Identity: 26% (114 aa)

KLGEGSFAKVREGLHVLTG------------EKVAIKVIDKKRAKKD------------------------TYVTKNLRREGQIQQM-------IRHPNI
.||.|||.||... | .|.            .|||||.||||..|..                         .  ||.||| .| ..       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TQLLDILE------------TENS--------YYLVM---ELCPGG----NLMHKIYEK---------------KRLEESEARRYIRQLISAVEHLHRAG
 .|... |            | .         .|.||   |.|.||     |  .| |.               .|..|.|||||.||..|||...|  .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKIENLLLDED-----------------NNIKLIDFGLSNCAGILG---------------------YSDPFSTQCGSPAYAA-PELLARKK---
.|||||| ||.|||..                 ||||.||||..|                           . ....|.||.|.|.| ||.| .|.   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YGPKIDVWSIGVNMYAMLTGTLPFTVEP-----------FSLRALYQKMVDKEMNPLPTQLST-----------------------GAI
           ||||.|.||.|| .|.||.|..||  .            .... |..|    . .  | ..|.                        ..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SFLRSLLEPDPVKRPNIQQALANRWL
...|..|..|| ||..|.|.|.  |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase HUNK.AA AMPK 62-320 44 1.7e-109 326.19 In-house 1-254 (254) Show / Hide 
Range on Protein: 62-320
Range on HMM: 1-254/254
Sequence Identity: 44% (115 aa)

LIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDIL-ETENSYYLVMELCPGGNLMHKIYEKKRLEE
 |   ..|||.| ||  | | |||||||||...|.. |... | . ..|| .| ...|||.|.|| ... ||.   ..|||  .|| |   |  ..||.|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVER-IQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

SEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKIDVWSIGVNMYAMLTG
 ||.|.. | ||.|| .|| ..|||||| ||||||...|||. ||||||   .    .  .| |||| |||||. . |.| ||..|.|| || .|||| |
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSN---MMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCG

TLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWL
.|||  .  . ..||.| .. |  ..|. ||. | . ....|..||.|| .|..  .  |.
YLPF--DDENTPTLYKKIKNGEY-YIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase HUNK.AA S_TKc 62-320 35 2.9e-99 336.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 62-320
Range on HMM: 1-231/231
Sequence Identity: 35% (98 aa)

LIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPG--GNLMHKIYEKKR--
    ||.|.|.|.||. . |. ||..||||.|.           ...||| || .. .|||| .|.|. .. ...|.|||.|.|  |.|.. | ...|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGP-KIDVWSIGVN
    . | .||.|..|...|.|..|. |..||||| ||.||||  .||..||||.            .|.||.| | |||.|   .||. |.|.||.|. 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

MYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALA-------NRWL
.| ||.|  ||      . ....|..           |  |..|.| .|. || ||| . .||.         |.
LYEMLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase HUNK.AA MARK 61-320 38 8.4e-99 323.56 In-house 1-262 (262) Show / Hide 
Range on Protein: 61-320
Range on HMM: 1-262/262
Sequence Identity: 38% (105 aa)

YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDT-YVTKNLRREGQIQQMIRHPNITQLLDILE--TENS-YYLVMELCPGGNLMHKIYEK-
| .. . .|.||.|||. ..|..||.|||||...|.  |..     ||..|| .| ... ||||..|... |  ||.   ||.||...||.|.. |... 
YKML-KTIGHGSYAKVKLACHKHTGRKVAIKIYEKF--KLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHP

-KRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN--NIKLIDFGLSNCA--GILGYSDPFSTQCGSPAYAAPELLARKKYG-PKIDVWSI
  ||.|.||||. ||..|||. .|. ..||||.| ||.|.||..  |||.||||.|.|   | .      .| ||.|.|.|||.. .|.|  ||.|.|| 
NGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-----LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSL

GVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWL
|| .|.|..|..||     ..  ||.|..  .    |. .|... .....|| ..| .|| |.. .  .|.
GVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase HUNK.AA Pkinase 62-320 30 3.7e-89 307.31 Pfam 1-293 (293) Show / Hide 
Range on Protein: 62-320
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

LIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGG----NLMHKIY--EK
.   ||.|.|||..|... |. ||..||.|.|.|...|..  .|. ...| || ....|||| .|.|. |.....|.|||.|.||     |.. |   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KRL--EESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNI----KLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA-RKKYGPKIDVWS
...  .| |...|..|.....|..|. |..||||| ||.|.|....|    |..||||. ..  .  .  ..| ||.| |.|||..  ...||||.|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGVNMYAMLTGTLPFTVEP-----FSLRALYQKMVD---KEMNPLPTQLS-----------------TGAISFLRSLLEPDPVKRPNIQQALANRWL
.|. .| ||.| .||  .       . ......  .   ..  | .   |                   ...|....|..|| |||...|.|   |.
CGCILYEMLCGRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase HUNK.AA HUNK 213-320 60 1.5e-80 260.71 In-house 321-433 (433) Show / Hide 
Range on Protein: 213-320
Range on HMM: 321-433/433
Sequence Identity: 60% (68 aa)

ILGYSDPFSTQCGSPAYAAPELLAR-KKYGPKIDVWSIGVNMYAMLTGTLPFTVEP--FSLRALYQKMVDKEMNPLPTQLS--TGAISFLRSLLEPDPVK
|.||.|.|.|.||||||||||...| |.||||.|||||||||||||||||||||||  |..|.|.||....|||..|.|..  |....|||..||||...
IFGYEDFFKTHCGSPAYAAPEIYCRGKDYGPKVDVWSIGVNMYAMLTGTLPFTVEPPEFNMRHLHQKIMKGEMNVHPKQMTHLTDCDMFLRRKLEPDKIQ

RPNIQQALANRWL
|.|.|.....||.
RVNLQNKMDHRWM
Kinase HUNK.AA CAMK1 61-263 42 1.5e-79 230.87 In-house 1-216 (276) Show / Hide 
Range on Protein: 61-263
Range on HMM: 1-216/276
Sequence Identity: 42% (93 aa)

YLIGSRKLGEGSFAKVREGLHVLT---GEKVAIKVID-KKRAKKDT--YVTKNLRREGQIQQ---MIRHPNITQLLDILETENSYYLVMELCPGGNLMHK
| .|. ..|.|.|..|... |  |   |...|||.|| ||  ||..     ..|..| .| .    | |||| .. .. |..| .||||||. || | ..
YEFGK-EIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

IYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLL---DEDNNIK--LIDFGLSNCAGILGYSD-PFSTQCGSPAYAAPELLAR---KKYGP
| ||.   | .||. ..|..||||..|  |.|||||| ||||.   |||  ||  ..|||||    |..  .   .|.||.| | ||| |..   | |. 
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSK---IFDHDENLMKTACGTPGYVAPEVLECKKDKPYDK

KIDVWSIGVNMYAMLTGTLPF
..|.|||||  | .|.|  ||
ACDMWSIGVITYILLCGYPPF
Kinase HUNK.AA QIK 61-320 36 7.8e-78 264.89 In-house 1-272 (272) Show / Hide 
Range on Protein: 61-320
Range on HMM: 1-272/272
Sequence Identity: 36% (104 aa)

YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKR---
| |. | .| | || |. . |  | .|||||.||| .  .. . .| . || ||  |..||.|. |....||..  |.|.| |..| . . . .. |   
YDIE-RTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEE-NLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGV

-----------------LEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDP-FSTQCGSPAYAAPELLARKK
                 ..|.||||   |..|||...|. ..|||||| ||.|||.. |||..|||.||    . ...   .| ||||.|||||..  |.
KMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSN----WFKQGQLLMTWCGSPPYAAPEMFEGKE

Y-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWL
| |||.|.||.|| .|.. .| |||  .  .|  | |...      .|  .|..  .. |  |  || .| .|.| .  ||.
YDGPKVDIWSMGVVLYVLVCGALPFDGK--TLQNLRQRVLSGKFR-IPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase HUNK.AA Ciliate-E2 62-320 23 7.2e-75 255.05 In-house 1-365 (365) Show / Hide 
Range on Protein: 62-320
Range on HMM: 1-365/365
Sequence Identity: 23% (87 aa)

LIGSRKLGEGSFAKVREGLHVLTGEKVAIKV-------------IDKKRAKKDTYVTKNLRREGQIQQMIR-------------------HPNITQLLDI
 .  .|.|.|.|..|... . ......|||.              ..|   . ..  ....   |.....|                   |||| .. . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--TENSYYLVMELCPGGNLMHKIYEK-----------KRLEESEARRYIRQLIS---------------AVEHLHRAG-VVHRDLKIENLLLDEDNNI
 .  ..|..|||||.| ||.|.. |...           |.. | |......|...               |.|.||  . ..|||.| ||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGLS-----------------------NCAGILGYS------DPFSTQCGSPAYAAPELLARKK---------YGPKIDVWSIGVNMYAMLTGTLP
|.||||||                       .  .  ||.      . | |.||.| | ||| | .||         |. |.|.||.|| .| ||.| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FTVEPFSLRALYQKMVDKEMNP-------------LPTQLSTGAISFLRS----LLEPDPVKRPN-IQQALANRWL
|      ..   |. .|   .               . ..|  .. ...     .|. || ||.. ..|.| . |.
F------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase HUNK.AA MELK 61-320 41 1.7e-72 247.04 In-house 1-254 (254) Show / Hide 
Range on Protein: 61-320
Range on HMM: 1-254/254
Sequence Identity: 41% (108 aa)

YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEE
| .   ..| | ||||.   |.||...||||..||..  .|      .. | .  . .|| .| ||  ..|||. ...||| ||||...  | ...||||
YEV-HDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHD---LPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEE

SEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPF--STQCGSPAYAAPELLARKKY-GPKIDVWSIGVNMYAML
.|.| . ||..||. ..|  |  ||||| ||||.||| ..|||||||  ||   |  |     | |||||||||||.  |.| |   ||||.|. .|...
EETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGL--CAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLM

TGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWL
 | |||  .   ....|.|..    .  |  ||  ..  || .|  || ||  ... |   |.
CGFLPF--DDDNMMIMYKKIMSGCYE-EPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase HUNK.AA TSSK 62-264 39 7.6e-72 235.08 In-house 1-230 (289) Show / Hide 
Range on Protein: 62-264
Range on HMM: 1-230/289
Sequence Identity: 39% (92 aa)

LIGSRKLGEGSFAKVREGLHVLTGEK----------------VAIKVIDKKRAKKDTYVTKNLRREGQIQQM-IRHPNITQLLDILETEN-SYYLVMELC
.. ..|.|.||.|||... .  .  |                ||||.||.|.|..| |. | | || ||  . ..|||| |.. ..||..   |.|||..
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTD-YLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYA

PGGNLMHKIYEK------KRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSN-CAGILGYSDPF----STQCGSPAYAAP
 .| |  .| ..      ..|.|..||.  ||..|||...|  .||||||| ||.|||...||||.||| .. ..   ....      .| ||| |||||
EHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPR--DDPGRCCHLSKTFCGSYAYAAP

ELLARKKYGPKI-DVWSIGVNMYAMLTGTLPFT
| |  ..| ||  |||| ||  |.|..|..||.
EILRGIPYDPKWYDVWSMGVILYIMVCGCMPFD
Kinase HUNK.AA Pkinase_Tyr 62-208 29 5.1e-20 68.43 Pfam 1-158 (270) Show / Hide 
Range on Protein: 62-208
Range on HMM: 1-158/270
Sequence Identity: 29% (47 aa)

LIGSRKLGEGSFAKVREGLHV----LTGEKVAIKVIDKKRAKKD-TYVTKNLRREGQIQQMI-RHPNITQLLDILE-TENS--YYLVMELCPGGNLMHKI
..  .|||||.| .|..|        |. .||.|.. |  | ..     . . || .|   . .|||| .|. .    . .  .|.|||..|.|.| .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

YE----KKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLS
 .    |..|  ..   . .|  .. |.|.. . .||||   | |..|.| .|  ||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase HUNK.AA TyrKc 62-319 22 5e-17 52.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 62-319
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

LIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMI--RHPNITQLLDILETE-------NSYYLVMELCPGGNLMHKI
.   .||||| | .|..|      ..||.|.. .          . ..|| .|  ..  .|||| .|. .  ..         ...|||..|.|.| . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

YEKKR-LEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSD------PFSTQC----GSP-----AYAAPELLA
 .... |  ..   .  |  .  |.||. ...||||   | |..|.. .|  |||||      .|.|                |.         ||| . 
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS----RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

RKKYGPKIDVWSIGVNMYAMLTGTLPFTVEP----FSLRALYQKMVDKEMNPLPTQ--------LSTGAISFLRSLLEPDPVKRPNIQQALANRW
 .|. .| |||| || |. ..|   .   ..     | . ....  . .. | |           ..   .  ..  . || .||. ..    ..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase HUNK.AA CAMK1 296-320 40 2.8e-09 23.04 In-house 252-276 (276) Show / Hide 
Range on Protein: 296-320
Range on HMM: 252-276/276
Sequence Identity: 40% (10 aa)

FLRSLLEPDPVKRPNIQQALANRWL
|.. .||.|| ||....|.|. .|.
FIKHMLEVDPKKRYTCEQCLNHPWI
Kinase HUNK.AA TSSK 289-320 28 5.8e-07 18.86 In-house 258-289 (289) Show / Hide 
Range on Protein: 289-320
Range on HMM: 258-289/289
Sequence Identity: 28% (9 aa)

LSTGAISFLRSLLEPDPVKRPNIQQALANRWL
.|. ... .|..|.|.| .||.|.. ... |.
ISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase HUNK.AA APH 175-208 21 0.00053 14.53 Pfam 165-202 (248) Show / Hide 
Range on Protein: 175-208
Range on HMM: 165-202/248
Sequence Identity: 21% (8 aa)

EHLHRAGVVHRDLKIENLLLD--EDNNIK--LIDFGLS
.|.......|.|..  |...|  .|..    .||.. .
AHWPPPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDA
UBA_CAMKL HUNK.AA UBA_CAMKL 344-382 24 1.2e-09 32.89 In-house 1-41 (41) Show / Hide 
Range on Protein: 344-382
Range on HMM: 1-41/41
Sequence Identity: 24% (10 aa)

SPSVVLHMTEKL-GYKNSDVINTVLSNRA-CHILAIYFLLN
 .... .| ... |..  ..|.....|..  || |.|.|| 
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL