Gene GPRK7 (Human)

GPRK7

Species: Human
Alias: GRK7, GPRK7
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 3q22-q23,

Classification

Group: AGC
Family: GRK
Subfamily: GRK

Sequence

Name Sequence Type Origin Length Description Download
GPRK7.NA RNA Sugen Kinome 1746 None Fasta, JSON
GPRK7.AA Protein Sugen Kinome 553 None Fasta, JSON
GPRK7.kin_dom Protein Kinase Domain Sugen Kinome 264 None Fasta, JSON

Protein domain

Protein domains of GPRK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RGS GPRK7.AA RGS 55-176 20 1e-19 72.73 SMART 1-121 (121) Show / Hide 
Range on Protein: 55-176
Range on HMM: 1-121/121
Sequence Identity: 20% (25 aa)

NFHSLCEQQPIGRRLFRDFLATVPTF-RKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPGNPQPFLSQAVATKCQAATTEEERVAAVTLAKAE
.||.||...|||||.||.|| . .        |........ .|.     .. . .  .  | .||   ........ ..||.. .. .   .   |...
SFHHLCDNDPIGRRYFREFLKQEFCEYKENLEFWLACEEFKKMED-EERRQKAREIYDKYISPNAPCEHCVNIDHHTREQCQQCLCN-PHPDCFDEAQRH

AMAFLQEQPFKDFVTSAFYDKFL
 . .... ....|. | .|...|
VYQLMEKDSYPRFLRSDYYKRYL
RGS GPRK7.AA RGS 55-105 30 1.5e-09 33.53 Pfam 1-55 (124) Show / Hide 
Range on Protein: 55-105
Range on HMM: 1-55/124
Sequence Identity: 30% (17 aa)

NFHSLCEQQPIGRRLFRDFLAT-VPTFRKAATFLEDVQNWELA---EEGPTKDS-A
.||.||. |||||||||.|| .  . .  .  |..... .. .   ..  ...  |
SFHHLCNDQPIGRRLFRQFLESEFCEY-ENIEFWLACEDFKKMFSDSDEKMHQKDA
RGS GPRK7.AA RGS 124-175 13 0.005526 11.89 Pfam 72-124 (124) Show / Hide 
Range on Protein: 124-175
Range on HMM: 72-124/124
Sequence Identity: 13% (7 aa)

PFLSQAVATKCQAATTE-EERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKF
.... .. ..||.  .. ..   .   |...   .... ..  |. | .|..|
HNIDHDTREHCQDNLEQAQPTPDCFDEAQRHIYTLMEKDSYPRFLKSDYYQRF
Kinase GPRK7.AA GRK 191-454 62 1.5e-209 702.49 In-house 1-265 (265) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-265/265
Sequence Identity: 62% (165 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVG-TRGLD
|...|||||||||||||.||..||||||||||.|||.||..||.|||.||.|||||.|.|.||||||.|.|..|||||..||||||||||||.| ..|.|
FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEQMALNEKQILEKVHSRFVVSLAYAYETKDALCLVMTIMNGGDLKFHIYNMGENPGFD

MSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEMVAGRT
..|.|||.|.|.||. |||...||||||||||.||||.|..|.||||||||...|..|..|.||.||||||...... |....||...||.||||..||.
EERAIFYAAEICCGLEHLHRERIVYRDMKPENILLDDHGHIRISDLGLAVEIPEGQMIRGRVGTVGYMAPEVVKNER-YTFSPDWWGLGCLIYEMIEGRS

PFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRLFLAKKPEQRLGSREK-SDDPRKHHFF
||...||||..|....|...|..|..|..|.||||||||..|.|.||||||.||. .|..|.|.||
PFRQRKEKVKREEVDRRVKEDPEKYSHEKFSEEAKDICRMLLHKDPEQRLGCREEGCDEVRQHPFF
Kinase GPRK7.AA GRK 191-454 56 1e-205 654.81 In-house 1-272 (272) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-272/272
Sequence Identity: 56% (154 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSP---FIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGT--
|...|||||||||||||.||..||||||||.|||||.||..||.|||.||.|||||.|.   |||..|||.|.|..|||||..||||||..||||.|   
FRQYRVLGKGGFGEVCACQVRATGKMYACKCLDKKRIKKRKGETMALNEKQILEKVHSRDCPFIVCMAYAYETKDALCLVMTIMNGGDLHYHIYNMGNNE

RGLDMSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQR-AGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEM
.|.|..|..||.|.|.||. |.|...|||||.||||.|||| |..|.||||||.|...|.|.... .||.||||||.|.....|....||...||.||||
PGFDEERMRFYAAEICCGLEHMHRRRIVYRDLKPENILLDDHGHVRISDLGLACEIPEGQPMIHGRVGTHGYMAPEVLQNERAYDFSPDWWSLGCMIYEM

VAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRLFLAKKPEQRLGSREK---SDDPRKHHFF
..|..||...||||..|....|...|.||.. |.|.|||||||. .|.|.||||||.|..   ......|.||
IEGHSPFRQHKEKVKREEVDRRVKEDPVKYP-DKFSEEAKDICEMLLQKDPEQRLGCRGGTCGAQEVKEHPFF
Kinase GPRK7.AA AGC 191-454 27 1.6e-140 365.81 In-house 1-395 (395) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-395/395
Sequence Identity: 27% (108 aa)

FTEFRVLGKGGFGEVCAVQVK------NTGKMYACKKLDKKR---LKKKGGEKMALLE------------KEILEKVS----------SPFIVS-LAYAF
|   .|.|||.||.|. |. |       |||.||.|.|.||.   .|||  ..... |            ..||||..          .||||. | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ESKTH--LCLVMSLMN---------GG-DLKFHIYNV-GTRGLDMSRVIFYSAQ-------IACGMLHLHE-LGIVYRD-MKPENVLLDDLGNCRLSDLG
..|.|  |..|| .|.         || .| .|.... . . .| .|. || |.       |.... .||. .||..|| .||||.|||. |...|.| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAVEMK---------------------------------------------------GGKPITQRAG--TNGYMAPEILMEKVSYSYPVDWFA--MGCSI
|. |..                                                   ...  .   |  |  |||||||     |....|| .  .|| .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YEMVAGRTPFKD------------YKEKVSKEDLKQRTLQDEVKFQH---------DNFTEEAKDICRLFLAKKPEQRLGSREK------SDDPRKHHFF
|||..|..|| .             .|.  |    .......||| .         ..|..||||... .| | ||.|||....       .. ..| .|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase GPRK7.AA S_TKc 191-454 31 5.9e-84 286.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNG--GDLKFHIYNVGTRG-
..  |..|||.||.|. .. |.||. .|.|...          .... | .||.|   |.|| | ..|.. .||..|| ...|  |||. .| . |..| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDMSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPEILMEKVSYSY-PVDWFAMGCSIYE
   ..  .. || .||.|.. ..|..||..|| ||||.|||.  .  ..| ||| ..      |   ||  |||||.|    .|.. ..|| . || .||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRLFLAKKPEQRLGSREKSD---DPRKHHFF
|..|..||         . . .. .           ..||||. |  | | ||.|..  |      | ..| .|
MLCGYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GPRK7.AA BARK 191-454 41 1.1e-74 254.47 In-house 1-264 (264) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-264/264
Sequence Identity: 41% (111 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSP----FIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTR
|   |..|.||||||       |||||| | |||||.| | || .|| |. .|. ||      ||| ..|||..   || .. ||||||| .|.   |  
FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGV-

GLDMSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEMVA
      ..|| | |  |. |.|.  .||||.|| |.|||. |  |.|||||| .    ||     || ||||||.|   ..|    |||..|| .| .. 
-FSEQEMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHAS-VGTHGYMAPEVLQKGTAYDSSADWFSLGCMLYKLLR

GRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRLFLAKKPEQRLGSREK-SDDPRKHHFF
|  ||.  | |  |... . ||  .|..  |.| .| .|.    | .  ..||| . . ... ..| ||
GHSPFRQHKTK-DKHEIDRMTLTMNVELP-DSFSKEMRDLLEGLLQRDVSKRLGCMGRGAQEVKEHPFF
Kinase GPRK7.AA SGK 191-454 32 2.2e-70 216.43 In-house 1-283 (283) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-283/283
Sequence Identity: 32% (95 aa)

FTEFRVLGKGGFGEVCAVQVKNT------------------GKMYACKKLDKKRLK-------KKGGEKMALLEK-EILEKVSSPFIVSLAYAFESKTHL
|    |.|||.||.|  |. | .                  .|.|| | | |.          ||  .|  . |.  || ....||||.| |||  |. |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAV-EMKGGKPITQRAGTNGYMAPEILM
 .||  .|||.. .|.     . .  .|. || |.|.| . .||.. |.||| ||||.|||. |.|.| | ||.  ..|  .  .  .||  |.|||.| 
YFVMDYVNGGEMFYHLQR--EKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL-

EKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFF
 |  ..  |||. .||  |||  |  ||    .   |. . .  .  . .. . ... .|.|.  . |.| |..|||... . . ..| ||
RKQPHDRTVDWWCLGCVLYEMMYGLPPF----YSRNKQQMYDNIINQPLQIPP-QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase GPRK7.AA Pkinase 191-454 27 5e-70 243.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-293/293
Sequence Identity: 27% (84 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALL--EKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGG----DLKFHIY---
..  |..|.|.||.|.  . |.|||..|.|...|.  .|.. .. ...  | .|. ....|.|| | ..||.|.|...|| ...||    ||. .|    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

NVGTRGLDMSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNC----RLSDLGLAVE--MKGGKPITQRAGTNGYMAPEILMEKVSYSYPVDWF
. .   ...  ..||  ||..|. ..|. ||..||.||||.|.|. |..    ...| |||       .   | ..|| .|||||....   |...||..
HGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

AMGCSIYEMVAGRTPFKDY---KEKVSKEDLKQRTLQDEVKFQHDNFT--------------------EEAKDICRLFLAKKPEQRLGSREKSDDPRKHH
..|| .|||. ||.||..    .. ...  . .|... ...|. ..                      ||.||...  |.|.|..|..     ..  .| 
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHP

FF
.|
WF
Kinase GPRK7.AA AktR 191-454 34 2.5e-67 229.99 In-house 1-268 (268) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-268/268
Sequence Identity: 34% (94 aa)

FTEFRVLGKGGFGEVCAVQVK-NTGKMYACKKLDKKRLKKKGGEKMALLEKEILE-KVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGL
|.  ..||||.||.|  || | ...|.|| | ..|| ....  .. ...|. |.| ... |||| | |.|..|..| ..|. . ||.| .|. . ..  .
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKK--F

DMSRVIFYSAQIACGMLHLHEL-GIVYRDMKPENVLLDDLGNCRLSDLGLAV--EMKGGKPITQR-AGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEM
. ... ||.|||  .  .||.   |.|||.|||| |||  |. ...| ||.    |.   ....   ||. |||||....|. . ..||| | |. ||||
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

VAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQH-DNFTEEAKDICR-LFLAKKPEQRLG-SREKSDDPRKHHFF
|.| .||  | ..   . .|... |  .||.   .|....||..    | | |..||| ...  .. ..| .|
VTGCPPF--YHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase GPRK7.AA Ciliate-E2 191-454 20 1.2e-65 224.37 In-house 1-365 (365) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-365/365
Sequence Identity: 20% (79 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKM-----------------------YACKKLDKKRLKKKGGEKMAL----------LEKEILEKVSSPFIVSLAYA
.   ...|.|.|| |. ..|....|.                       || | . |. .. .  |.  .           ||.|||....|.|. . ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--SKTHLCLVMSLMNGGDLKFHIYNV----------GTRGLDMSRVIFYSAQIAC---------------GMLHLHELG-IVYRDMKPENVLLDDLGN
|.  ..... ||| . .||||. .|.|           .   ...  ......||.                .. .||. . |..|| ||||.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

CRLSDLG-------------------LAVEMKGGKPITQR--------------AGTNGYMAPEILM-EKVS-------YSYPVDWFAMGCSIYEMVAGR
. ..|.|                   .  . |. . .|..              .|| ||||||||. .| .       |.| .|....|. .|||. |.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

TPFKDYKEKVSKEDLKQRTLQDEVKFQ-----------------HDNFTEEAKDICRL----FLAKKPEQRLGSREKSDDPRKHHFF
.||             |  .| ...|.                 ... ..|.||...      | |.||.|..     ..  .|..|
PPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase GPRK7.AA Ciliate-E2-Unclassified 191-454 21 2e-64 220.37 In-house 1-352 (352) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-352/352
Sequence Identity: 21% (77 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKMY-----ACKKLDKKRLKKKGGEKMALLEKEILEKVS-------------------SPFIVSLAYAFESKTHLCL
..  ...|.||||.|. .| |...  |     ..|. ..|.....  .   ..|...... .                   .|||| . |.|..| ....
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMSLMNGGDLKFHIYNVGT---------------RGLDMSRVI-----FYSAQIACGMLHLHELG-IVYRDMKPENVLLDDLG---NCRLSDLGLA----
|| ...||||...| . ..               . ..   ..     || ||| .|  .||. . |..|| ||||.|.|. |   .....|.|..    
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--VEMKGGKP-----------ITQRAGTNGYM----APEILMEKVSYS---YPVDWFAMGCSIYEMVAGRTPFKDYKEKV------------SKEDLKQR
  .. . ..            .....||..||    |||.|...  .    | .|....|. .|||. |. ||.|....              .. |.| 
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

TLQDEVKFQH-------DNFTEEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFF
 .| ...|..       ..  .||||... .| |... ....|   ..  .|..|
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GPRK7.AA RSK 194-454 30 3.9e-64 219.37 In-house 1-278 (278) Show / Hide 
Range on Protein: 194-454
Range on HMM: 1-278/278
Sequence Identity: 30% (85 aa)

FRVLGKGGFGEVCAVQVK---NTGKMYACKKLDKKRLKKKGG-EKMALLEKEILEKVS-SPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRG-
 .|||.||.|.|  .. .   .||. || | |.|. ....    . .. | .||| .  .||||.| |||. ...| |.| ...||.|  |... .. | 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDMSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDD---LGNCRLSDLGLAVEM--KGGKPITQRAGTNGYMAPEILM---EKVSYSYPVDWFAMGC
.. ... || |.|.. . |||..||..|| ||||.|.||    |  .|.| |.. ..  . ...     .|  |||||.|.    .. ..  .||.  |.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

SIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDE--VKFQ-HDNFTEEAKDICRLFLAKKPEQRLGS-REKSDDPRKHHFF
 .||| .|..||.   .. ..... .| .. .  ...   .. ..||||. |  | . |..|||. ..  .. ..| .|
LMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase GPRK7.AA Eta 191-454 37 6.2e-58 196.92 In-house 1-261 (261) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-261/261
Sequence Identity: 37% (102 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSS-PFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLD
|.  .||||| || |   ..|.|. .|| | | |  . .       . || ||      ||. .|  .|  |  |  ||  .||||| |.|    .|  |
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQR--ARKFD

MSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVE-MKGGKPITQRAGTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEMVAGR
 .|  || | . | .  ||. |..|||.| .|.|||  | |.| | |.  | .  |.  |   ||  |.||||| | . |   |||.|||  .|||..|.
EPRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQE-MEYGPSVDWWAMGVLMYEMMCGQ

TPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRLFLAKKPEQRLGSRE---KSDDPRKHHFF
 ||    |    .|| .  |.|.| .      .||  | . |. | |..|||. .     .. |.| ||
PPFEADNE----DDLFESILHDDVLYPV-WLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase GPRK7.AA TyrKc 191-454 22 1.1e-14 14.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 191-454
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKV--SSPFIVSLAYAFESK-------THLCLVMSLMNGGDLKFHI-
 |  ..|| | ||||.  . |    . | |.| .        ... . | .|. |.  . | || |  .  ..         |..|| .| .|||| .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

YNVGTRGLDMSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGG-------KPITQRA--GTNG-----YMAPEILMEKV
.. ..  | |.  . .. |||||| .||. ... ||    |.|... . .. || ||. . . .       . ....   |...      |||| .....
KHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

SYSYPVDWFAMGCSIYEMVA-GRTPFKD---YKEKVSKEDLKQRTLQDEVKFQHDN--------FTEEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFF
 ..   | .. |  ..|.   | .|  .      ..| ... ..  | .   | .|         ..|  .| .   . .||.|   .|       |..|
-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase GPRK7.AA S_TK_X 455-534 20 1.3e-05 24.94 SMART 1-79 (79) Show / Hide 
Range on Protein: 455-534
Range on HMM: 1-79/79
Sequence Identity: 20% (18 aa)

KTINFPRLEA--GLIEPPFVPDPSVVYAKDIAEIDDFS--EVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETG----LFEELNDPN
. |.. .|..  . |||||.|... ||| .   .  |   . ...          ... .......||.| .||.     |....  .
RGIDWDKLYNQQKEIEPPFKPKIKEVYA-SPTDTSNFDPEFTEETPM-------LTPDDPPLSNSMWQNE-METEIPPDPFRGFTYVF
Kinase GPRK7.AA Pkinase_Tyr 263-338 28 1.9e-05 19.04 Pfam 81-158 (270) Show / Hide 
Range on Protein: 263-338
Range on HMM: 81-158/270
Sequence Identity: 28% (22 aa)

HLCLVMSLMNGGDLKFHIYNV--GTRGLDMSRVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLA
....|| .| .|||. .  .   . . |.|.. . ...|||.|| .|.. ... ||    |.|... . .. .| |||
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA