Gene EphA10 (Human)

EphA10

Species: Human
Alias: MGC43817, FLJ33655, EPHA10, FLJ16103, EphA10
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 1p34.3,

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
EphA10.NA RNA Sugen Kinome 5526 None Fasta, JSON
EphA10.AA Protein Sugen Kinome 1008 None Fasta, JSON
EphA10.kin_dom Protein Kinase Domain Sugen Kinome 255 None Fasta, JSON

Protein domain

Protein domains of EphA10.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ephrin_lbd EphA10.AA Ephrin_lbd 35-211 63 6.2e-136 423.79 Pfam 1-190 (190) Show / Hide 
Range on Protein: 35-211
Range on HMM: 1-190/190
Sequence Identity: 63% (121 aa)

EVILLDSKASQAELGWTALPSNG---------WEEISGVDEHDRPIRTYQVC-NVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE
||.|.|.|. ...||||. |.||         |||.||.||..||||||||| || ||||.|||.|.||.|.  |||.|||.||.|||.|.||.||||||
EVVLMDTKTATSDLGWTTYPYNGRDDFWMEPQWEEVSGMDENGRPIRTYQVCDNVMEPNQNNWLRTNWIERRGAQRIYVELKFTMRDCNSFPGVAGTCKE

TFNVYYLETEA--DLGRGRPRLGGSRPRKIDTIAADES-FTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQC
|||.||.|...  |.|. .|..  .. .|||||||||| |||.|.|.|.||||||||.|||||.|||.|||||.|||.|||||||||| |
TFNLYYYESDHYDDAGKEHPNWMENQYTKIDTIAADESRFTQRDFGSRWMKLNTEVRSIGPLSKRGFYLAFQDQGACMALVSVRVYYKKC
EPH_lbd EphA10.AA EPH_lbd 35-211 62 2.4e-114 387.08 SMART 1-184 (184) Show / Hide 
Range on Protein: 35-211
Range on HMM: 1-184/184
Sequence Identity: 62% (115 aa)

EVILLDSKASQAELGWTALPSNG--WEEISGVDEHDRPIRTYQVCNVLE---PNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAG-TCKETFNV
||.|.|.|. ..|||||. |..|  |||.||.|||..|||||||||| |   |||.|||.|.||.|.  |||.|||.||.|||.|.||.|| .||||||.
EVVLMDTKTETGELGWTTYPPHGGTWEEVSGMDEHHNPIRTYQVCNVMEINEPNQNNWLRTHWIYRRGAQRIYVELKFTMRDCNSMPGVAGVSCKETFNL

YYLETEADLG-RGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQC
|| |...| .   .|    .. .||||||||||||| |.|.|.||.|||||..||||..|| |||||.|||.|||||||.|| |
YYYESDNDHATAHTPFWMENPYIKIDTIAADESFTQRDFGDRVMKMNTEVRSFGPLSKKGFYLAFQDQGACMALVSVRVFYKKC
NCD3G EphA10.AA NCD3G 282-308 37 0.000405 14.2 Pfam 28-54 (54) Show / Hide 
Range on Protein: 282-308
Range on HMM: 28-54/54
Sequence Identity: 37% (10 aa)

CEACPPGFYKVSPRRPLCSPCPEHSRA
|. ||.| |  ..    | ||||. ..
CIPCPEGEYSNTTDSYTCTPCPEDQWP
FN3 EphA10.AA FN3 338-435 18 1.2e-07 32.71 SMART 1-69 (69) Show / Hide 
Range on Protein: 338-435
Range on HMM: 1-69/69
Sequence Identity: 18% (21 aa)

PSAPRD---LQYSLSRSP-----LVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPG----ARYTVRV
|..|..   |. .   |        ..|.| ||        |.|.                                   .|. .|.||     .|..||
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------------------YTVTGLKPGQYPWTEYEFRV

AALNG-VSGPA
.| ||   |. 
RAVNGNDAGEG
FN3 EphA10.AA FN3 451-537 24 3.3e-11 44.48 SMART 1-69 (69) Show / Hide 
Range on Protein: 451-537
Range on HMM: 1-69/69
Sequence Identity: 24% (24 aa)

PGAPWEEDEIRRDRVEPQ------SVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPA----TRYVFQIRAAS---PGPS
||.|    ..|   | .       ||.||| .|             ...|                   .|||.|||     |.|.|..|| .    |..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Kinase EphA10.AA Eph 645-900 57 2.6e-183 615.28 In-house 1-264 (264) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-264/264
Sequence Identity: 57% (153 aa)

VTLERSLGGGRFGELCCGCLQLP-GRQEL---LVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEG
...|...|.|.|||.|||.|.|| |..|.   .||...|.......||. ||.|| ..|||||..|.|||||||.....||||||| .|.|| |||.|.|
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

QLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKIS--GFGRGPRDRS--EAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIM
|....||.|.|.|.||.|||||.|.||||.||||..||.|.||||.|  |..|...|..  ||.|||..|..|..|.|||......|.|||||||.||.|
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVM

WEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
||||..|||||||||.||||||.|.|.|||||..||. ||.|||||||||. .||.|.||.|||
WEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase EphA10.AA TK 645-900 22 1.5e-100 337.86 In-house 1-486 (486) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-486/486
Sequence Identity: 22% (111 aa)

VTLERSLGGGRFG---ELCCGCLQLPGR----------------------QELLVAVHMLR--DSASDSQRLG-----------FLAEALTLGQFD----
.||.. || | ||   | . | .. ...                      ..  ||| ||.  |..|. ...            ||.||. . ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HSHIVRLEGVVTRGST------------LMIVTEYMSHGA----LDGFLRRHEG---------------------------------------------
 | .|||| ||.|.| .            .|||.|||.||     |. .||.. .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------QLVAGQLMGLLPGLASAMKYLSEM------GYVHRGLAARHVLVSSDLV-----------CKISGFG---
                              ||   ||.     .|..| ||...      ..||| |||| .||....|           |||. ||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RGPRDRSEAVYTTMS-------------------------GRSPALWAAPETLQ---------FGHFSSASDVWSFGIIMWEVMAFG-ERPYWDM
     .  .. |.  |...|                         |. |  | |||.|.         .|.|...|||||||. |||.. .| | .|..|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SG---------QDVIKAVEDG--------------FRLPPPRNCP--------------NLLHRLMLDCWQKDPGERPRFSQIHSIL
|          |.|.. ...|              .|.|.| .||               ....||..||..|| .||.|||.|. |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase EphA10.AA Pkinase_Tyr 645-900 40 5.4e-99 335.89 Pfam 1-270 (270) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-270/270
Sequence Identity: 40% (110 aa)

VTLERSLGGGRFGELCCGCLQ-LPGRQELLVAVHMLRDSASDSQ--RLGFLAEALTLGQF-DHSHIVRLEGVVT-RGST--LMIVTEYMSHGALDGFLRR
.|. . || | ||| . | .  .|. ... ||| ||...|...|  |  |..|| .. |. .| .|||| ||.| .|    ..||.||| || |. .||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H---EGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDR-SEAVY-TTMS-GRSPALWAAPETLQFGHFSSASDVWS
|   ...|   .| .     |..| ||......|| |||| .||....|.||. ||   ||  ..  | .. . |. |  | ||| ...| |...|||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL-ARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGIIMWEVMAFGERP-YWDMSGQDVIKAV-EDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
||. |||.. .|| | |..|| ..|.... ||| |.|.|.|||  ...||..||..|| .||.||.||..|
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase EphA10.AA TyrKc 645-900 36 2.4e-91 310.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-280/280
Sequence Identity: 36% (107 aa)

VTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQF--DHSHIVRLEGVVTRG-------STLMIVTEYMSHGALDGFL
.||.. || | ||| . | .       . ||| ||...|    |  |. ||  . ..  .| .|||| ||.| .         ||||.|||.||.|. .|
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

RRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG---RGPRD----RSEAVYTTM---SGR--SPALWAAPETLQFGHF
|.|...|   .|       |. | ||......|| |||| .||......||| ||    .  |     |. .|...   .|.   |  | |||....| |
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SSASDVWSFGIIMWEVMAFGERPYWD-----MSGQDVIKAVEDGFRLPPPRN--------CPNLLHRLMLDCWQKDPGERPRFSQIHSIL
...|||||||. |||.. .|. ||..     || |.||. |..|.|.|.| |        ||  ....|..||. || .||.||.||...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase EphA10.AA UTK 645-900 34 7.5e-77 261.63 In-house 1-296 (296) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-296/296
Sequence Identity: 34% (103 aa)

VTLERSLGGGRFGELCCGCLQLPG--RQELLVAVHMLRDSASDSQRLG----FLAEAL---TLGQFD-HSHIVRLEGVVTRGSTLMIVTEYMSHGALDGF
| | | || |.||| . . .. .   ..|..|||. .. .|.. |       |. ||     ..||. | ...|| ||.|... .|||||||. | |. .
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRRHEGQLV-------AGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSD-------LVCKISGFG------RGP-------RDRSEAVYTTMSGR
||||  ..          |...     |..| ||...|.||| |||| .|| ..       .||||..||      | .       .. |. .. .  .|
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

SPALWAAPETLQFG-HFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDG--FRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
 |  | ||| |  . .|...|||||||. .||....| .|| .|| ..|...|..|   |.|.|. ||  . |||..||..|| |||.| .. . .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase EphA10.AA TK-Unique 645-900 32 1.2e-76 260.94 In-house 1-294 (294) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-294/294
Sequence Identity: 32% (96 aa)

VTLERSLGGGRFGELCCGCLQLPG---RQELLVAVHMLRDSASDSQRLGFLAEALTLGQFD-HSHIVRLEGVVTRGS-TLMIVTEYMSHGALDGFLRRHE
.......| |.||. . | .  .     .   ||| ||.|.|.| ..  || |.  . . . | .||...|. |. .   ||. ||.. | |...||.  
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

GQ-------------------------LVAGQLMGLLPGLASAMKYLSE--MGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTM-S-GRSPA
..                         .  ..|   . ..|..|.||..  .. ||| |.||.||...|.||||..||. .. . . || .| | || | 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

LWAAPETLQ--FGHF-SSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNC-PNLLHRLMLDCWQKDPGERPRFSQIHSIL
 | ||| |.   |.. .. |||||||..|||.. .|..|| .|.  |......||.|.| | .| .. .. ||  |||..| ||| |.|| ..|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase EphA10.AA Src 645-900 38 1.5e-72 245.78 In-house 1-255 (255) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-255/255
Sequence Identity: 38% (102 aa)

VTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLR-RHEGQ-L
..|.| || | |||   |      ...  |||  |.      .   ||.|| .. ...| ..|.|  |....    ||||||||| |  .|. . ||. |
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL

VAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRS--EAVYTTMSG-RSPALWAAPETLQFGHFSSASDVWSFGIIMWEV
   ||  .    |. |.||..| |.|| |||| |||. ..|||.  ||   |     . .|.  .| . |  | ||| ...|.|.  |||||||| ..|.
HLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLA-RLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEI

MAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHR-LMLDCWQKDPGERPRFSQIHSIL
. .|  ||  |. ..|...|| |.|.| |.|||  |.  .|| ||.||| .|| |  ... |
VTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase EphA10.AA Abl 645-900 34 2.5e-64 213.31 In-house 1-252 (252) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-252/252
Sequence Identity: 34% (90 aa)

VTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLV-
....  |||| .||   |  .   | .. |||  |.. . . .   ||.||  . .  |  .|.| || || .   |.||.|..| |  .||. . ... 
IMMKHKLGGGQYGEVYEGVWK---RHDCTVAVKTLKEDTMEVHE--FLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELP

AGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSG-RSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAF
|  |. .   .||.|.|| .  ..|| ||||  ||. . . |.  ||   |   . .||   | . |  | ||| | . .||| |||| ||...||.  .
AVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLA-RMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATY

GERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
|  ||  .  ..| . .|.|.|.  |. ||.   .||. ||| .. .||.| .||  .
GMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase EphA10.AA SrcB 645-901 38 2.2e-63 213.27 In-house 1-251 (251) Show / Hide 
Range on Protein: 645-901
Range on HMM: 1-251/251
Sequence Identity: 38% (100 aa)

VTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEG-QLV
. |.. || | |||   |  .    ..  |||  ... .   .   |||||  . .  | ..|||  |||.   . |.|||| .|.|  ||.  || .| 
LKLVKKLGAGQFGEVWMGYYN----NHMKVAVKTMKQGTMSPE--AFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLS

AGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSG-RSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAF
  .|. .   .|  | |. .| |.|| | |  .|||  |.|||  ||   |   .  ||   | . |  | ||| ..|| |   ||||||||.. |.. .
LPKLIDMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLA-RIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTY

GERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILS
|  ||  |.  .||...| |.|.| | |||. | ..|  ||.. | ||| |  ..|.| 
GRIPYPGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase EphA10.AA Trk 645-900 34 1.1e-61 207.89 In-house 1-275 (275) Show / Hide 
Range on Protein: 645-900
Range on HMM: 1-275/275
Sequence Identity: 34% (96 aa)

VTLERSLGGGRFGELCCG-CLQLPGRQE-LLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRH----
. | . || | ||  . . | .|.. |. ..|||  |.| ||.. |  |  ||  | . .| |||.. || | .  |..| ||| || |  .|| |    
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKD-ASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

-----------EGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSGRS--PALWAAPETLQFGHFSS
            | |. .|.       || | |. .  .||| .|.|  ||  .|. ||. ||   .  |   | .. ..   |  |  ||  ..  |. 
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTY

ASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFR-LPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
 |||||||..|||.. .|  |.. .| . ||  .  |   |  || ||  .  .|| |||..| .|    .|| |.
ESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase EphA10.AA CTKA 758-900 45 9.9e-56 185.68 In-house 144-290 (290) Show / Hide 
Range on Protein: 758-900
Range on HMM: 144-290/290
Sequence Identity: 45% (67 aa)

MKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSGRS--PALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDV
| ||.||| ||| ||.| .|. .  . ||. || |   |.|. | ..| ..  |  | |||.|.|| ||.|||||.||...||.| .|| |.  || | |
MNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEV

IKAVEDG--FRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
 .|.  .   |||.|||||  |  .|  ||.  | .|| | ..   |
CQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase EphA10.AA Musk 755-900 37 2.6e-48 157.61 In-house 136-282 (282) Show / Hide 
Range on Protein: 755-900
Range on HMM: 136-282/282
Sequence Identity: 37% (55 aa)

ASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSGRS-PALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQ
|  | ||||| .||| || |  |. .  . ||. ||   .  ..  |        |  | .|| .    |. .||||..|...||.  ... ||. |.  
ACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHE

DVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
.||. . .|..|  | |||  .. ||  |||| | .|| | ||| ..
EVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase EphA10.AA S_TKc 645-904 19 5e-17 63.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 645-904
Range on HMM: 1-231/231
Sequence Identity: 19% (52 aa)

VTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSH--GALDGFLRRHEGQ-
 .. | .| | ||. ...          .||. ...          .. |   | . .| .||.| .|    . | .|.||...  | |  ..... .. 
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSS-ASDVWSFGIIM
    .   .   ..  ...|..|. ..| .|| |    .|...  . ||. ||   .         ..      . ||| |   ...  ..|.||.|.|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

WEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHS-----ILSKMV
.| .. |. |..    | ..| .            .  .  ..  |.|||| .||   ..        .   .
YEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase EphA10.AA Musk 645-736 36 2e-16 50.57 In-house 1-94 (282) Show / Hide 
Range on Protein: 645-736
Range on HMM: 1-94/282
Sequence Identity: 36% (34 aa)

VTLERSLGGGRFGE--LCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLR
.  .|..| | ||          .|. .|..||| ||.| ||.     |  ||  . .|||  ||.| ||   |  .    |||. | |. ||.
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLH
Kinase EphA10.AA CTKA 673-737 38 1.9e-15 48.25 In-house 36-102 (290) Show / Hide 
Range on Protein: 673-737
Range on HMM: 36-102/290
Sequence Identity: 38% (26 aa)

LVAVHMLRDSASDSQRLGFLAEALTLG--QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRR
.||| ||.| | . .|  ||.|| .|   .|.|  ..|| ||.|.   .  ..|.|. | |  .||.
DVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYLRA
Kinase EphA10.AA Pkinase 812-891 18 3.1e-10 37.25 Pfam 177-282 (293) Show / Hide 
Range on Protein: 812-891
Range on HMM: 177-282/293
Sequence Identity: 18% (20 aa)

WAAPETLQ-FGHFSSASDVWSFGIIMWEVMAFGERPYWDM----SGQDVIKAVEDGFRLPPPRNCP-----------------------NLLHRLMLDCW
..||| ..   . ....|.||.|.|..|..  |. |...     .  | .. ..   . |.....|                         .  .. .|.
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

QKDPGERP
.||| .||
CKDPKKRP
Kinase EphA10.AA Pkinase 645-738 21 1.3e-05 20.93 Pfam 1-100 (293) Show / Hide 
Range on Protein: 645-738
Range on HMM: 1-100/293
Sequence Identity: 21% (22 aa)

VTLERSLGGGRFGELCCGCLQLPGRQELLVAV-HMLRDSASDSQRLGFLA--EALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHG----ALDGFLR-
 ...| .| | ||.  . |     ..  .|||  . .........   .   |.  .  ..| .|||| ....... . .|.||. .|     |  ... 
YHIGRKIGSGSFGCV-YKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-RH
 ||
WRH
SAM_1 EphA10.AA SAM_1 931-995 31 3.4e-19 70.94 Pfam 1-66 (66) Show / Hide 
Range on Protein: 931-995
Range on HMM: 1-66/66
Sequence Identity: 31% (21 aa)

TFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVS-LGISLAEHREALLSGISALQ
.  .| .|. |||.... .|.|.|..||| .......||..||.. .|. |. ||  ... |  | 
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGVTLPGHRKKIMYSIQMLK
SAM_2 EphA10.AA SAM_2 930-995 29 2.4e-18 65.8 Pfam 1-71 (71) Show / Hide 
Range on Protein: 930-995
Range on HMM: 1-71/71
Sequence Identity: 29% (21 aa)

STFPSFGSVGAWLEALDL-CRYKDSFAAAGYGSLEAV-AEMTAQDL--V-SLGISLAEHREALLSGISALQ
  ...| .|..||..... |.|||.| ..|. ..|.. | ||..||     .||... ||  ....|  ..
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
Sam7 EphA10.AA sam7 933-995 25 6.4e-18 61.56 In-house 1-70 (70) Show / Hide 
Range on Protein: 933-995
Range on HMM: 1-70/70
Sequence Identity: 25% (18 aa)

PSFGSVGAWLEALDL---CRYKDSFAAAGY----GSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQ
..| .|. |||....   ..|.|.| ..|.     .......|| .|| ..||..  ||  ... |  ..
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM EphA10.AA SAM 930-997 26 1.4e-17 65.68 SMART 1-67 (67) Show / Hide 
Range on Protein: 930-997
Range on HMM: 1-67/67
Sequence Identity: 26% (18 aa)

STFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQAR
   ... .|..|||....|.||| |...|. . . ..... .|| ..||... ||  .|..|. ....
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ